Project name: 90a72fa9e02dd0e

Chain sequence(s)	A: IVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEYQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSA
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.8783
• Maximal score value: 1.8188
• Average score: -0.8477
• Total score value: -201.7447

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
16	I	A	0.0000
17	V	A	-1.2666
18	G	A	-1.0669
19	G	A	-0.9095
20	T	A	-0.9061
21	N	A	-1.4817
22	S	A	0.0000
23	S	A	-0.2579
24	W	A	0.2656
25	G	A	-0.5732
26	E	A	-0.6695
27	W	A	0.0000
28	P	A	-0.6423
29	W	A	0.0000
30	Q	A	0.0000
31	V	A	0.0000
32	S	A	0.0000
33	L	A	0.0000
34	Q	A	0.0000
35	V	A	0.0000
36	K	A	-2.0330
37	L	A	-0.3239
38	T	A	-0.3599
38A	A	A	-0.8795
38B	Q	A	-1.8863
39	R	A	-2.2342
40	H	A	0.0000
41	L	A	-0.4532
42	C	A	0.0000
43	G	A	0.0000
44	G	A	0.0000
45	S	A	0.0000
46	L	A	0.0000
47	I	A	-0.0674
48	G	A	-0.6602
49	H	A	-1.2029
50	Q	A	-1.3622
51	W	A	0.0000
52	V	A	0.0000
53	L	A	0.0000
54	T	A	0.0000
55	A	A	0.0000
56	A	A	0.0000
57	H	A	-0.4289
58	C	A	0.0000
59	F	A	0.0000
60	D	A	-0.8351
60A	G	A	-0.4422
60B	L	A	-0.0674
60C	P	A	-0.1767
61	L	A	0.0148
62	Q	A	-1.5562
65	D	A	-2.4261
65C	V	A	-1.0476
65D	W	A	0.0000
65E	R	A	-1.4356
66	I	A	0.0000
67	Y	A	0.0000
68	S	A	0.0786
69	G	A	-0.0324
70	I	A	0.2110
71	L	A	-0.1707
72	N	A	-0.9571
73	L	A	-0.9761
74	S	A	-1.2237
75	D	A	-2.2244
76	I	A	-1.3504
77	T	A	-1.9034
78	K	A	-2.7074
79	D	A	-2.7892
80	T	A	-1.5998
81	P	A	-0.7826
82	F	A	-0.2423
83	S	A	-0.7011
84	Q	A	-1.9629
85	I	A	0.0000
86	K	A	-3.4678
87	E	A	-2.7968
88	I	A	-0.5404
89	I	A	0.1847
90	I	A	0.3634
91	H	A	0.0000
92	Q	A	-1.7575
93	N	A	-2.0036
94	Y	A	-1.4329
95	K	A	-1.7460
96	V	A	0.0842
97	S	A	-0.4088
98	E	A	-1.0515
99	G	A	-0.9505
100	N	A	-1.4528
101	H	A	-1.2956
102	D	A	0.0000
103	I	A	0.0000
104	A	A	0.0000
105	L	A	0.0000
106	I	A	0.0000
107	K	A	-1.8818
108	L	A	0.0000
109	Q	A	-2.1771
110	A	A	-1.1633
111	P	A	-0.9973
112	L	A	-0.9523
113	N	A	-1.4613
114	Y	A	-1.1230
115	T	A	-1.1313
116	E	A	-1.7046
117	F	A	-0.3109
118	Q	A	-1.0202
119	K	A	-1.5753
120	P	A	-0.5671
121	I	A	0.0000
122	C	A	0.2820
123	L	A	0.0402
124	P	A	0.0000
125	S	A	-1.3911
126	K	A	-2.2502
127	G	A	-1.5524
128	D	A	-1.0836
129	T	A	-0.9976
130	S	A	-0.2130
131	T	A	0.5318
132	I	A	1.8188
133	Y	A	0.0000
134	T	A	-0.0822
135	N	A	-0.8596
136	C	A	0.0000
137	W	A	-0.3369
138	V	A	0.0000
139	T	A	0.0000
140	G	A	0.0000
141	W	A	0.0000
142	G	A	0.0000
143	F	A	-1.8361
144	S	A	-1.8214
145	K	A	-2.9922
146	E	A	-2.6732
147	K	A	-2.9772
148	G	A	-2.6196
150	E	A	-2.6737
151	I	A	-1.2447
152	Q	A	-1.0459
153	N	A	-1.5078
154	I	A	-0.7201
155	L	A	0.0000
156	Q	A	0.0000
157	K	A	-0.8301
158	V	A	0.0000
159	N	A	-0.8463
160	I	A	0.0000
161	P	A	-0.1366
162	L	A	0.5806
163	V	A	-0.0985
164	T	A	-0.8861
165	N	A	-2.2865
166	E	A	-3.1008
167	E	A	-2.6056
168	Y	A	0.0000
169	Q	A	-3.1426
170	K	A	-3.6357
171	R	A	-2.9236
172	Y	A	0.0000
173	Q	A	-3.0003
173A	D	A	-2.7949
174	Y	A	-1.8760
175	K	A	-2.5330
176	I	A	0.0000
177	T	A	-1.6359
178	Q	A	-2.0420
179	R	A	-1.5121
180	M	A	0.0000
181	V	A	0.0000
182	C	A	0.0000
183	A	A	0.0000
184	G	A	0.0000
184A	Y	A	-1.7813
185	K	A	-3.3732
186	E	A	-3.7481
186A	G	A	0.0000
186B	G	A	-2.2617
186C	K	A	-2.0429
189	D	A	0.0000
190	A	A	0.0000
191	C	A	0.0000
192	K	A	-2.3044
193	G	A	-0.9059
194	D	A	0.0000
195	S	A	-0.4143
196	G	A	0.0000
197	G	A	0.0000
198	P	A	0.0000
199	L	A	0.0000
200	V	A	0.0000
201	C	A	0.0000
202	K	A	-1.6262
203	H	A	-1.3991
204	N	A	-1.7704
205	G	A	-1.2382
208	M	A	-0.5225
208C	W	A	-0.5543
208D	R	A	-0.6546
209	L	A	0.0000
210	V	A	0.0000
211	G	A	0.0000
212	I	A	0.0000
213	T	A	0.0000
214	S	A	0.0000
215	W	A	-0.2560
216	G	A	-0.6782
217	E	A	-0.9457
219	G	A	-1.3874
220	C	A	0.0000
221	A	A	-2.2528
221A	R	A	-3.0614
222	R	A	-3.8783
223	E	A	-3.0764
224	Q	A	-2.2835
225	P	A	0.0000
226	G	A	0.0000
227	V	A	0.0000
228	Y	A	0.0000
229	T	A	0.0000
230	K	A	-0.8831
231	V	A	0.0000
232	A	A	0.0000
233	E	A	-1.5593
234	Y	A	0.0000
235	M	A	0.0000
236	D	A	-1.9793
237	W	A	0.0000
238	I	A	0.0000
239	L	A	-0.9767
240	E	A	-2.4667
241	K	A	-1.7114
242	T	A	-1.2220
243	Q	A	-1.7965
244	S	A	-1.3614
245	A	A	-0.8167