Project name: 926379c8fbe0e6

Chain sequence(s)	A: MKYLFSPSLMCMNLIKLNEQISVLNSKADFLHVDIMDGHFVKNITLSPFFIEQIKSYVNIPIDAHLMVENPGDYIEICEKSGASFITIHAETINREAFRIIDRIKSHGLMVGIALNPATPISEIKHYINKIDKITIMTVDPGFAGQPFIPEVLEKIRDLKRLKDDNNYNYLIEADGSCNKNTFQVLKDAGCKVFVLGSSGLFNLSDDLGKAWEIMIGNFNG
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.3727
• Maximal score value: 2.0367
• Average score: -0.6552
• Total score value: -144.7913

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.3487
2	K	A	-0.9137
3	Y	A	-0.5094
4	L	A	0.0000
5	F	A	0.0000
6	S	A	0.0000
7	P	A	0.0000
8	S	A	0.0000
9	L	A	0.0000
10	M	A	0.4441
11	C	A	0.0966
12	M	A	0.0000
13	N	A	0.2395
14	L	A	1.6542
15	I	A	2.0367
16	K	A	0.2067
17	L	A	0.1446
18	N	A	-1.1556
19	E	A	-1.1108
20	Q	A	0.0000
21	I	A	0.0000
22	S	A	-0.7118
23	V	A	-0.5302
24	L	A	0.0000
25	N	A	-0.6276
26	S	A	-0.7595
27	K	A	-0.8557
28	A	A	-0.4947
29	D	A	-0.7222
30	F	A	0.0000
31	L	A	0.0000
32	H	A	0.0000
33	V	A	0.0000
34	D	A	0.0000
35	I	A	0.0000
36	M	A	0.0000
37	D	A	-0.8538
38	G	A	-0.9674
39	H	A	-1.8155
40	F	A	-1.3256
41	V	A	0.0000
42	K	A	-1.4888
43	N	A	0.0053
44	I	A	1.5029
45	T	A	1.1153
46	L	A	0.9013
47	S	A	0.8838
48	P	A	0.6103
49	F	A	1.4863
50	F	A	0.0000
51	I	A	0.0000
52	E	A	-1.3539
53	Q	A	-1.0306
54	I	A	0.0000
55	K	A	-1.2801
56	S	A	-0.8042
57	Y	A	0.0091
58	V	A	-0.4648
59	N	A	-1.1217
60	I	A	-0.5685
61	P	A	-0.3453
62	I	A	0.0000
63	D	A	0.0000
64	A	A	0.0000
65	H	A	0.0000
66	L	A	0.0000
67	M	A	0.0000
68	V	A	0.0000
69	E	A	-2.9025
70	N	A	-2.7036
71	P	A	0.0000
72	G	A	-1.9121
73	D	A	-2.2377
74	Y	A	-0.9685
75	I	A	0.0000
76	E	A	-1.3869
77	I	A	0.2286
78	C	A	0.0000
79	E	A	0.0000
80	K	A	-1.7470
81	S	A	-1.0011
82	G	A	-1.0536
83	A	A	0.0000
84	S	A	-0.0819
85	F	A	0.0000
86	I	A	0.0000
87	T	A	0.0000
88	I	A	0.0000
89	H	A	0.0000
90	A	A	0.0000
91	E	A	-1.3240
92	T	A	-1.7077
93	I	A	0.0000
94	N	A	-2.3103
95	R	A	-2.5918
96	E	A	-1.7593
97	A	A	0.0000
98	F	A	-0.4079
99	R	A	-2.0142
100	I	A	0.0000
101	I	A	0.0000
102	D	A	-2.0294
103	R	A	-1.8681
104	I	A	0.0000
105	K	A	-1.7287
106	S	A	-1.2325
107	H	A	-1.5469
108	G	A	-0.8304
109	L	A	-0.4353
110	M	A	-0.0760
111	V	A	0.0000
112	G	A	0.0000
113	I	A	0.0000
114	A	A	0.0000
115	L	A	0.0000
116	N	A	0.0000
117	P	A	-0.5576
118	A	A	-0.3354
119	T	A	-0.3534
120	P	A	-0.5554
121	I	A	-0.4692
122	S	A	-0.9162
123	E	A	-1.3006
124	I	A	0.0000
125	K	A	-1.7387
126	H	A	-1.6919
127	Y	A	0.0000
128	I	A	0.0000
129	N	A	-2.0805
130	K	A	-1.4394
131	I	A	0.0000
132	D	A	-0.9584
133	K	A	0.0000
134	I	A	0.0000
135	T	A	0.0000
136	I	A	0.0000
137	M	A	0.0000
138	T	A	0.0000
139	V	A	0.0000
140	D	A	-0.7290
141	P	A	0.0000
142	G	A	0.0000
143	F	A	0.9397
144	A	A	0.2048
145	G	A	-0.4032
146	Q	A	-0.4544
147	P	A	-0.4553
148	F	A	-0.3189
149	I	A	-0.3878
150	P	A	-1.1026
151	E	A	-2.3646
152	V	A	0.0000
153	L	A	-1.9220
154	E	A	-3.0998
155	K	A	-2.1645
156	I	A	0.0000
157	R	A	-2.8221
158	D	A	-2.4303
159	L	A	0.0000
160	K	A	-2.6695
161	R	A	-3.0298
162	L	A	-2.2446
163	K	A	-2.7376
164	D	A	-3.3727
165	D	A	-3.1981
166	N	A	-2.4570
167	N	A	-2.7823
168	Y	A	-1.9043
169	N	A	-1.7599
170	Y	A	0.0000
171	L	A	-0.2418
172	I	A	0.0000
173	E	A	0.0000
174	A	A	0.0000
175	D	A	0.0000
176	G	A	-0.2011
177	S	A	-0.6569
178	C	A	0.0000
179	N	A	-1.6225
180	K	A	-2.6301
181	N	A	-2.2196
182	T	A	0.0000
183	F	A	0.0000
184	Q	A	-2.1388
185	V	A	-0.9334
186	L	A	0.0000
187	K	A	-1.8758
188	D	A	-2.3524
189	A	A	0.0000
190	G	A	-1.8951
191	C	A	0.0000
192	K	A	-0.9884
193	V	A	0.0000
194	F	A	0.0000
195	V	A	0.0000
196	L	A	0.0000
197	G	A	-0.3117
198	S	A	-0.5012
199	S	A	-0.8578
200	G	A	0.0000
201	L	A	0.0000
202	F	A	-1.0878
203	N	A	-1.4503
204	L	A	-0.5788
205	S	A	-1.7007
206	D	A	-2.9016
207	D	A	-2.7912
208	L	A	0.0000
209	G	A	-1.5320
210	K	A	-2.0885
211	A	A	0.0000
212	W	A	-0.4872
213	E	A	-0.7181
214	I	A	-0.0129
215	M	A	0.0000
216	I	A	-0.3544
217	G	A	-0.9178
218	N	A	-1.6433
219	F	A	0.0000
220	N	A	-1.6292
221	G	A	-1.6536