Project name: 926379c8fbe0e6
Status: done
submitted: 2018-06-29 08:15:56, status changed: 2018-06-29 08:25:08
Settings
Chain sequence(s)
|
A: MKYLFSPSLMCMNLIKLNEQISVLNSKADFLHVDIMDGHFVKNITLSPFFIEQIKSYVNIPIDAHLMVENPGDYIEICEKSGASFITIHAETINREAFRIIDRIKSHGLMVGIALNPATPISEIKHYINKIDKITIMTVDPGFAGQPFIPEVLEKIRDLKRLKDDNNYNYLIEADGSCNKNTFQVLKDAGCKVFVLGSSGLFNLSDDLGKAWEIMIGNFNG
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.3727
-
Maximal score value
-
2.0367
-
Average score
-
-0.6552
-
Total score value
-
-144.7913
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
M |
A |
0.3487 |
|
2 |
K |
A |
-0.9137 |
|
3 |
Y |
A |
-0.5094 |
|
4 |
L |
A |
0.0000 |
|
5 |
F |
A |
0.0000 |
|
6 |
S |
A |
0.0000 |
|
7 |
P |
A |
0.0000 |
|
8 |
S |
A |
0.0000 |
|
9 |
L |
A |
0.0000 |
|
10 |
M |
A |
0.4441 |
|
11 |
C |
A |
0.0966 |
|
12 |
M |
A |
0.0000 |
|
13 |
N |
A |
0.2395 |
|
14 |
L |
A |
1.6542 |
|
15 |
I |
A |
2.0367 |
|
16 |
K |
A |
0.2067 |
|
17 |
L |
A |
0.1446 |
|
18 |
N |
A |
-1.1556 |
|
19 |
E |
A |
-1.1108 |
|
20 |
Q |
A |
0.0000 |
|
21 |
I |
A |
0.0000 |
|
22 |
S |
A |
-0.7118 |
|
23 |
V |
A |
-0.5302 |
|
24 |
L |
A |
0.0000 |
|
25 |
N |
A |
-0.6276 |
|
26 |
S |
A |
-0.7595 |
|
27 |
K |
A |
-0.8557 |
|
28 |
A |
A |
-0.4947 |
|
29 |
D |
A |
-0.7222 |
|
30 |
F |
A |
0.0000 |
|
31 |
L |
A |
0.0000 |
|
32 |
H |
A |
0.0000 |
|
33 |
V |
A |
0.0000 |
|
34 |
D |
A |
0.0000 |
|
35 |
I |
A |
0.0000 |
|
36 |
M |
A |
0.0000 |
|
37 |
D |
A |
-0.8538 |
|
38 |
G |
A |
-0.9674 |
|
39 |
H |
A |
-1.8155 |
|
40 |
F |
A |
-1.3256 |
|
41 |
V |
A |
0.0000 |
|
42 |
K |
A |
-1.4888 |
|
43 |
N |
A |
0.0053 |
|
44 |
I |
A |
1.5029 |
|
45 |
T |
A |
1.1153 |
|
46 |
L |
A |
0.9013 |
|
47 |
S |
A |
0.8838 |
|
48 |
P |
A |
0.6103 |
|
49 |
F |
A |
1.4863 |
|
50 |
F |
A |
0.0000 |
|
51 |
I |
A |
0.0000 |
|
52 |
E |
A |
-1.3539 |
|
53 |
Q |
A |
-1.0306 |
|
54 |
I |
A |
0.0000 |
|
55 |
K |
A |
-1.2801 |
|
56 |
S |
A |
-0.8042 |
|
57 |
Y |
A |
0.0091 |
|
58 |
V |
A |
-0.4648 |
|
59 |
N |
A |
-1.1217 |
|
60 |
I |
A |
-0.5685 |
|
61 |
P |
A |
-0.3453 |
|
62 |
I |
A |
0.0000 |
|
63 |
D |
A |
0.0000 |
|
64 |
A |
A |
0.0000 |
|
65 |
H |
A |
0.0000 |
|
66 |
L |
A |
0.0000 |
|
67 |
M |
A |
0.0000 |
|
68 |
V |
A |
0.0000 |
|
69 |
E |
A |
-2.9025 |
|
70 |
N |
A |
-2.7036 |
|
71 |
P |
A |
0.0000 |
|
72 |
G |
A |
-1.9121 |
|
73 |
D |
A |
-2.2377 |
|
74 |
Y |
A |
-0.9685 |
|
75 |
I |
A |
0.0000 |
|
76 |
E |
A |
-1.3869 |
|
77 |
I |
A |
0.2286 |
|
78 |
C |
A |
0.0000 |
|
79 |
E |
A |
0.0000 |
|
80 |
K |
A |
-1.7470 |
|
81 |
S |
A |
-1.0011 |
|
82 |
G |
A |
-1.0536 |
|
83 |
A |
A |
0.0000 |
|
84 |
S |
A |
-0.0819 |
|
85 |
F |
A |
0.0000 |
|
86 |
I |
A |
0.0000 |
|
87 |
T |
A |
0.0000 |
|
88 |
I |
A |
0.0000 |
|
89 |
H |
A |
0.0000 |
|
90 |
A |
A |
0.0000 |
|
91 |
E |
A |
-1.3240 |
|
92 |
T |
A |
-1.7077 |
|
93 |
I |
A |
0.0000 |
|
94 |
N |
A |
-2.3103 |
|
95 |
R |
A |
-2.5918 |
|
96 |
E |
A |
-1.7593 |
|
97 |
A |
A |
0.0000 |
|
98 |
F |
A |
-0.4079 |
|
99 |
R |
A |
-2.0142 |
|
100 |
I |
A |
0.0000 |
|
101 |
I |
A |
0.0000 |
|
102 |
D |
A |
-2.0294 |
|
103 |
R |
A |
-1.8681 |
|
104 |
I |
A |
0.0000 |
|
105 |
K |
A |
-1.7287 |
|
106 |
S |
A |
-1.2325 |
|
107 |
H |
A |
-1.5469 |
|
108 |
G |
A |
-0.8304 |
|
109 |
L |
A |
-0.4353 |
|
110 |
M |
A |
-0.0760 |
|
111 |
V |
A |
0.0000 |
|
112 |
G |
A |
0.0000 |
|
113 |
I |
A |
0.0000 |
|
114 |
A |
A |
0.0000 |
|
115 |
L |
A |
0.0000 |
|
116 |
N |
A |
0.0000 |
|
117 |
P |
A |
-0.5576 |
|
118 |
A |
A |
-0.3354 |
|
119 |
T |
A |
-0.3534 |
|
120 |
P |
A |
-0.5554 |
|
121 |
I |
A |
-0.4692 |
|
122 |
S |
A |
-0.9162 |
|
123 |
E |
A |
-1.3006 |
|
124 |
I |
A |
0.0000 |
|
125 |
K |
A |
-1.7387 |
|
126 |
H |
A |
-1.6919 |
|
127 |
Y |
A |
0.0000 |
|
128 |
I |
A |
0.0000 |
|
129 |
N |
A |
-2.0805 |
|
130 |
K |
A |
-1.4394 |
|
131 |
I |
A |
0.0000 |
|
132 |
D |
A |
-0.9584 |
|
133 |
K |
A |
0.0000 |
|
134 |
I |
A |
0.0000 |
|
135 |
T |
A |
0.0000 |
|
136 |
I |
A |
0.0000 |
|
137 |
M |
A |
0.0000 |
|
138 |
T |
A |
0.0000 |
|
139 |
V |
A |
0.0000 |
|
140 |
D |
A |
-0.7290 |
|
141 |
P |
A |
0.0000 |
|
142 |
G |
A |
0.0000 |
|
143 |
F |
A |
0.9397 |
|
144 |
A |
A |
0.2048 |
|
145 |
G |
A |
-0.4032 |
|
146 |
Q |
A |
-0.4544 |
|
147 |
P |
A |
-0.4553 |
|
148 |
F |
A |
-0.3189 |
|
149 |
I |
A |
-0.3878 |
|
150 |
P |
A |
-1.1026 |
|
151 |
E |
A |
-2.3646 |
|
152 |
V |
A |
0.0000 |
|
153 |
L |
A |
-1.9220 |
|
154 |
E |
A |
-3.0998 |
|
155 |
K |
A |
-2.1645 |
|
156 |
I |
A |
0.0000 |
|
157 |
R |
A |
-2.8221 |
|
158 |
D |
A |
-2.4303 |
|
159 |
L |
A |
0.0000 |
|
160 |
K |
A |
-2.6695 |
|
161 |
R |
A |
-3.0298 |
|
162 |
L |
A |
-2.2446 |
|
163 |
K |
A |
-2.7376 |
|
164 |
D |
A |
-3.3727 |
|
165 |
D |
A |
-3.1981 |
|
166 |
N |
A |
-2.4570 |
|
167 |
N |
A |
-2.7823 |
|
168 |
Y |
A |
-1.9043 |
|
169 |
N |
A |
-1.7599 |
|
170 |
Y |
A |
0.0000 |
|
171 |
L |
A |
-0.2418 |
|
172 |
I |
A |
0.0000 |
|
173 |
E |
A |
0.0000 |
|
174 |
A |
A |
0.0000 |
|
175 |
D |
A |
0.0000 |
|
176 |
G |
A |
-0.2011 |
|
177 |
S |
A |
-0.6569 |
|
178 |
C |
A |
0.0000 |
|
179 |
N |
A |
-1.6225 |
|
180 |
K |
A |
-2.6301 |
|
181 |
N |
A |
-2.2196 |
|
182 |
T |
A |
0.0000 |
|
183 |
F |
A |
0.0000 |
|
184 |
Q |
A |
-2.1388 |
|
185 |
V |
A |
-0.9334 |
|
186 |
L |
A |
0.0000 |
|
187 |
K |
A |
-1.8758 |
|
188 |
D |
A |
-2.3524 |
|
189 |
A |
A |
0.0000 |
|
190 |
G |
A |
-1.8951 |
|
191 |
C |
A |
0.0000 |
|
192 |
K |
A |
-0.9884 |
|
193 |
V |
A |
0.0000 |
|
194 |
F |
A |
0.0000 |
|
195 |
V |
A |
0.0000 |
|
196 |
L |
A |
0.0000 |
|
197 |
G |
A |
-0.3117 |
|
198 |
S |
A |
-0.5012 |
|
199 |
S |
A |
-0.8578 |
|
200 |
G |
A |
0.0000 |
|
201 |
L |
A |
0.0000 |
|
202 |
F |
A |
-1.0878 |
|
203 |
N |
A |
-1.4503 |
|
204 |
L |
A |
-0.5788 |
|
205 |
S |
A |
-1.7007 |
|
206 |
D |
A |
-2.9016 |
|
207 |
D |
A |
-2.7912 |
|
208 |
L |
A |
0.0000 |
|
209 |
G |
A |
-1.5320 |
|
210 |
K |
A |
-2.0885 |
|
211 |
A |
A |
0.0000 |
|
212 |
W |
A |
-0.4872 |
|
213 |
E |
A |
-0.7181 |
|
214 |
I |
A |
-0.0129 |
|
215 |
M |
A |
0.0000 |
|
216 |
I |
A |
-0.3544 |
|
217 |
G |
A |
-0.9178 |
|
218 |
N |
A |
-1.6433 |
|
219 |
F |
A |
0.0000 |
|
220 |
N |
A |
-1.6292 |
|
221 |
G |
A |
-1.6536 |
|