Chain sequence(s) |
H: QVQLLETGGGLVKPGQSLKLSCAASGFTFTSYAMHWVRQPPGKGLEWVAVVSYDGNYKYYADSVQGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKDSRLRSLLYFEWLSQGYFNPWGQGTTLTVSS L: DIQMTQSPSSLSASVGDRVTITCRSSQSITSWNKNYLAWYQQKPGKAPKLLIYWGSYLESGVPSRFSGSGSGTDFTLTISSLQPEDFATYYCQQHYRTPPSFGQGTKVEIKG |
Distance of aggregation | 5 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
1 | Q | H | -1.0466 | |
2 | V | H | 0.3816 | |
3 | Q | H | -0.4861 | |
4 | L | H | 0.0000 | |
5 | L | H | 1.1773 | |
6 | E | H | -0.0032 | |
7 | T | H | -0.1496 | |
8 | G | H | -0.2595 | |
9 | G | H | -0.2830 | |
11 | G | H | 0.1096 | |
12 | L | H | 1.5184 | |
13 | V | H | 0.0000 | |
14 | K | H | -1.7425 | |
15 | P | H | -0.4927 | |
16 | G | H | -0.6971 | |
17 | Q | H | -1.1500 | |
18 | S | H | -0.3078 | |
19 | L | H | 0.1078 | |
20 | K | H | -1.1180 | |
21 | L | H | 0.0000 | |
22 | S | H | 0.0000 | |
23 | C | H | 0.0000 | |
24 | A | H | 0.0245 | |
25 | A | H | 0.0000 | |
26 | S | H | -0.1674 | |
27 | G | H | -0.2892 | |
28 | F | H | 0.2418 | |
29 | T | H | -0.0064 | |
30 | F | H | 0.0000 | |
35 | T | H | -0.0352 | |
36 | S | H | 0.0041 | |
37 | Y | H | 0.1666 | |
38 | A | H | 0.0000 | |
39 | M | H | 0.0000 | |
40 | H | H | 0.0000 | |
41 | W | H | 0.0000 | |
42 | V | H | 0.0000 | |
43 | R | H | 0.0000 | |
44 | Q | H | -0.1438 | |
45 | P | H | -0.1022 | |
46 | P | H | -0.3476 | |
47 | G | H | -0.8335 | |
48 | K | H | -1.8179 | |
49 | G | H | -0.4792 | |
50 | L | H | 0.0000 | |
51 | E | H | -0.5519 | |
52 | W | H | 0.0000 | |
53 | V | H | 0.0000 | |
54 | A | H | 0.0000 | |
55 | V | H | 0.0000 | |
56 | V | H | 0.0000 | |
57 | S | H | 0.0000 | |
58 | Y | H | 0.0856 | |
59 | D | H | -0.9360 | |
62 | G | H | -0.5192 | |
63 | N | H | -1.2301 | |
64 | Y | H | -0.0306 | |
65 | K | H | -0.4491 | |
66 | Y | H | 0.1571 | |
67 | Y | H | 0.1928 | |
68 | A | H | -0.3002 | |
69 | D | H | -1.8122 | |
70 | S | H | -0.4649 | |
71 | V | H | 0.0000 | |
72 | Q | H | -1.2851 | |
74 | G | H | -0.7478 | |
75 | R | H | -0.4606 | |
76 | F | H | 0.0000 | |
77 | T | H | -0.0808 | |
78 | I | H | 0.0000 | |
79 | S | H | -0.1384 | |
80 | R | H | -0.3591 | |
81 | D | H | -0.7786 | |
82 | N | H | -0.6975 | |
83 | S | H | -0.6118 | |
84 | K | H | -1.8643 | |
85 | N | H | -1.0401 | |
86 | T | H | 0.0000 | |
87 | L | H | 0.0000 | |
88 | Y | H | 0.2382 | |
89 | L | H | 0.0000 | |
90 | Q | H | -0.5687 | |
91 | M | H | 0.0000 | |
92 | N | H | -0.6605 | |
93 | S | H | -0.3227 | |
94 | L | H | 0.0000 | |
95 | R | H | -1.2497 | |
96 | A | H | -0.5127 | |
97 | E | H | -1.8091 | |
98 | D | H | 0.0000 | |
99 | T | H | -0.0131 | |
100 | A | H | 0.0000 | |
101 | V | H | 0.3962 | |
102 | Y | H | 0.0000 | |
103 | Y | H | 0.0000 | |
104 | C | H | 0.0000 | |
105 | A | H | 0.0000 | |
106 | K | H | 0.0000 | |
107 | D | H | 0.0000 | |
108 | S | H | -0.3302 | |
109 | R | H | -1.3402 | |
110 | L | H | 0.8949 | |
111 | R | H | -1.5596 | |
111A | S | H | -0.2938 | |
111B | L | H | 0.4424 | |
111C | L | H | 0.0000 | |
111D | Y | H | 1.5253 | |
111V | F | H | 1.1448 | |
111W | E | H | -0.8409 | |
111X | W | H | 0.4592 | |
111Y | L | H | 0.3798 | |
111Z | S | H | -0.1376 | |
112 | Q | H | 0.0000 | |
113 | G | H | 0.0000 | |
114 | Y | H | 0.0000 | |
115 | F | H | 0.0000 | |
116 | N | H | -0.3179 | |
117 | P | H | -0.0778 | |
118 | W | H | 0.1429 | |
119 | G | H | -0.2361 | |
120 | Q | H | -1.2157 | |
121 | G | H | -0.2725 | |
122 | T | H | -0.0257 | |
123 | T | H | -0.0147 | |
124 | L | H | 0.0000 | |
125 | T | H | 0.1695 | |
126 | V | H | 0.0000 | |
127 | S | H | -0.1548 | |
128 | S | H | -0.4497 | |
1 | D | L | -1.7894 | |
2 | I | L | 0.0000 | |
3 | Q | L | -1.1983 | |
4 | M | L | 0.0000 | |
5 | T | L | -0.0532 | |
6 | Q | L | 0.0000 | |
7 | S | L | -0.1819 | |
8 | P | L | -0.1806 | |
9 | S | L | -0.2701 | |
10 | S | L | -0.3298 | |
11 | L | L | 0.1746 | |
12 | S | L | -0.2717 | |
13 | A | L | 0.0000 | |
14 | S | L | -0.1289 | |
15 | V | L | 0.8602 | |
16 | G | L | -0.2479 | |
17 | D | L | -1.3510 | |
18 | R | L | -2.0356 | |
19 | V | L | 0.0000 | |
20 | T | L | -0.0643 | |
21 | I | L | 0.0000 | |
22 | T | L | -0.0198 | |
23 | C | L | 0.0000 | |
24 | R | L | -1.9390 | |
25 | S | L | 0.0000 | |
26 | S | L | -0.3110 | |
27 | Q | L | -0.6422 | |
28 | S | L | -0.2507 | |
29 | I | L | 0.0000 | |
30 | T | L | -0.0683 | |
31 | S | L | 0.1659 | |
34 | W | L | 0.9405 | |
35 | N | L | -1.1839 | |
36 | K | L | -0.9832 | |
37 | N | L | -0.3626 | |
38 | Y | L | 0.1524 | |
39 | L | L | 0.0000 | |
40 | A | L | 0.0000 | |
41 | W | L | 0.0000 | |
42 | Y | L | 0.0000 | |
43 | Q | L | 0.0000 | |
44 | Q | L | 0.0000 | |
45 | K | L | -0.3673 | |
46 | P | L | -0.4017 | |
47 | G | L | -0.8334 | |
48 | K | L | -1.7858 | |
49 | A | L | -0.3080 | |
50 | P | L | 0.0000 | |
51 | K | L | -1.4846 | |
52 | L | L | 0.0000 | |
53 | L | L | 0.0000 | |
54 | I | L | 0.0000 | |
55 | Y | L | 0.0000 | |
56 | W | L | 0.4542 | |
57 | G | L | 0.0000 | |
65 | S | L | 0.0416 | |
66 | Y | L | 1.3659 | |
67 | L | L | 0.6869 | |
68 | E | L | -0.2133 | |
69 | S | L | -0.3507 | |
70 | G | L | -0.4531 | |
71 | V | L | 0.1712 | |
72 | P | L | -0.1347 | |
74 | S | L | -0.3699 | |
75 | R | L | -0.7522 | |
76 | F | L | 0.0000 | |
77 | S | L | -0.1549 | |
78 | G | L | 0.0000 | |
79 | S | L | -0.2539 | |
80 | G | L | -0.3004 | |
83 | S | L | -0.2689 | |
84 | G | L | -0.1430 | |
85 | T | L | -0.2118 | |
86 | D | L | -1.0268 | |
87 | F | L | 0.0000 | |
88 | T | L | -0.0253 | |
89 | L | L | 0.0000 | |
90 | T | L | -0.0256 | |
91 | I | L | 0.0000 | |
92 | S | L | -0.3986 | |
93 | S | L | -0.1286 | |
94 | L | L | 0.0000 | |
95 | Q | L | -0.3639 | |
96 | P | L | -0.6389 | |
97 | E | L | -1.8648 | |
98 | D | L | 0.0000 | |
99 | F | L | 0.5222 | |
100 | A | L | 0.0000 | |
101 | T | L | -0.1614 | |
102 | Y | L | 0.0000 | |
103 | Y | L | 0.0000 | |
104 | C | L | 0.0000 | |
105 | Q | L | 0.0000 | |
106 | Q | L | 0.0000 | |
107 | H | L | 0.0000 | |
108 | Y | L | 0.0299 | |
109 | R | L | -0.8474 | |
114 | T | L | 0.0000 | |
115 | P | L | -0.0395 | |
116 | P | L | 0.0000 | |
117 | S | L | 0.0197 | |
118 | F | L | 0.2632 | |
119 | G | L | 0.0000 | |
120 | Q | L | -1.2077 | |
121 | G | L | -0.2741 | |
122 | T | L | 0.0000 | |
123 | K | L | -1.0737 | |
124 | V | L | 0.0000 | |
125 | E | L | -1.1859 | |
126 | I | L | 0.0555 | |
127 | K | L | -1.6789 | |
128 | G | L | -0.7842 |