| Chain sequence(s) |
A: NESISTAVIDAINSGATLKDINAIPDDMMDDIYSYAYDFYNKGRIEEAEVFFRFLCIYDFYNVDYIMGLAAIYQIKEQFQQAADLYAVAFALGKNDYTPVFHTGQCQLRLKAPLKAKECFELVIQHSNDEKLKIKAQSYLDAIQ Q: LIPELKAPKS B: SISTAVIDAINSGATLKDINAIPDDMMDDIYSYAYDFYNKGRIEEAEVFFRFLCIYDFYNVDYIMGLAAIYQIKEQFQQAADLYAVAFALGKNDYTPVFHTGQCQLRLKAPLKAKECFELVIQHSNDEKLKIKAQSYLDAIQ |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 8 | N | A | -2.3105 | |
| 9 | E | A | -2.7834 | |
| 10 | S | A | -1.3625 | |
| 11 | I | A | -0.6513 | |
| 12 | S | A | 0.0000 | |
| 13 | T | A | -1.0066 | |
| 14 | A | A | -1.1327 | |
| 15 | V | A | 0.0000 | |
| 16 | I | A | -0.6743 | |
| 17 | D | A | -2.1715 | |
| 18 | A | A | 0.0000 | |
| 19 | I | A | 0.0000 | |
| 20 | N | A | -1.3426 | |
| 21 | S | A | -1.0975 | |
| 22 | G | A | 0.0000 | |
| 23 | A | A | -0.1828 | |
| 24 | T | A | 0.0283 | |
| 25 | L | A | 0.3335 | |
| 26 | K | A | -1.2883 | |
| 27 | D | A | -0.5741 | |
| 28 | I | A | -0.5892 | |
| 29 | N | A | -1.1959 | |
| 30 | A | A | -0.7490 | |
| 31 | I | A | -0.6481 | |
| 32 | P | A | -1.4697 | |
| 33 | D | A | -2.7869 | |
| 34 | D | A | -3.2348 | |
| 35 | M | A | -1.7061 | |
| 36 | M | A | 0.0000 | |
| 37 | D | A | -2.4741 | |
| 38 | D | A | -2.2423 | |
| 39 | I | A | -0.4439 | |
| 40 | Y | A | 0.0000 | |
| 41 | S | A | -0.6413 | |
| 42 | Y | A | -0.0696 | |
| 43 | A | A | 0.0000 | |
| 44 | Y | A | -1.0558 | |
| 45 | D | A | -1.9267 | |
| 46 | F | A | -2.0151 | |
| 47 | Y | A | 0.0000 | |
| 48 | N | A | -2.7498 | |
| 49 | K | A | -3.1639 | |
| 50 | G | A | -2.7448 | |
| 51 | R | A | -3.5620 | |
| 52 | I | A | -2.1515 | |
| 53 | E | A | -2.3005 | |
| 54 | E | A | -1.6993 | |
| 55 | A | A | 0.0000 | |
| 56 | E | A | -0.5432 | |
| 57 | V | A | 0.9703 | |
| 58 | F | A | 1.2413 | |
| 59 | F | A | 0.0000 | |
| 60 | R | A | 0.4605 | |
| 61 | F | A | 1.5943 | |
| 62 | L | A | 0.0000 | |
| 63 | C | A | 0.0000 | |
| 64 | I | A | 2.1471 | |
| 65 | Y | A | 0.7307 | |
| 66 | D | A | 0.2369 | |
| 67 | F | A | 0.2109 | |
| 68 | Y | A | 0.0945 | |
| 69 | N | A | -0.3038 | |
| 70 | V | A | -0.0002 | |
| 71 | D | A | -0.7666 | |
| 72 | Y | A | 0.0000 | |
| 73 | I | A | 0.0000 | |
| 74 | M | A | -0.4114 | |
| 75 | G | A | 0.0000 | |
| 76 | L | A | 0.0000 | |
| 77 | A | A | 0.0000 | |
| 78 | A | A | 0.0000 | |
| 79 | I | A | 0.0000 | |
| 80 | Y | A | 0.0000 | |
| 81 | Q | A | 0.0000 | |
| 82 | I | A | 0.1766 | |
| 83 | K | A | -1.3159 | |
| 84 | E | A | -2.6047 | |
| 85 | Q | A | -1.9536 | |
| 86 | F | A | -1.7618 | |
| 87 | Q | A | -1.9633 | |
| 88 | Q | A | -1.6495 | |
| 89 | A | A | 0.0000 | |
| 90 | A | A | 0.0000 | |
| 91 | D | A | -0.7759 | |
| 92 | L | A | -0.2765 | |
| 93 | Y | A | 0.0000 | |
| 94 | A | A | -0.3220 | |
| 95 | V | A | 0.0000 | |
| 96 | A | A | 0.0000 | |
| 97 | F | A | 0.0000 | |
| 98 | A | A | 0.0000 | |
| 99 | L | A | 0.1164 | |
| 100 | G | A | -0.7650 | |
| 101 | K | A | -1.3516 | |
| 102 | N | A | -2.3716 | |
| 103 | D | A | -2.9029 | |
| 104 | Y | A | 0.0000 | |
| 105 | T | A | -1.1559 | |
| 106 | P | A | 0.0000 | |
| 107 | V | A | 0.0000 | |
| 108 | F | A | 0.0000 | |
| 109 | H | A | -0.0975 | |
| 110 | T | A | -0.6443 | |
| 111 | G | A | 0.0000 | |
| 112 | Q | A | -0.5003 | |
| 113 | C | A | 0.0000 | |
| 114 | Q | A | -1.6142 | |
| 115 | L | A | -1.2509 | |
| 116 | R | A | -2.5265 | |
| 117 | L | A | -1.8660 | |
| 118 | K | A | -2.0572 | |
| 119 | A | A | -1.2147 | |
| 120 | P | A | -1.0683 | |
| 121 | L | A | -0.3162 | |
| 122 | K | A | -2.1451 | |
| 123 | A | A | 0.0000 | |
| 124 | K | A | -2.3158 | |
| 125 | E | A | -2.9151 | |
| 126 | C | A | -1.6366 | |
| 127 | F | A | 0.0000 | |
| 128 | E | A | -2.8057 | |
| 129 | L | A | -1.4776 | |
| 130 | V | A | 0.0000 | |
| 131 | I | A | -1.5126 | |
| 132 | Q | A | -1.6411 | |
| 133 | H | A | -1.8368 | |
| 134 | S | A | -2.6810 | |
| 135 | N | A | -3.1741 | |
| 136 | D | A | -3.5421 | |
| 137 | E | A | -3.4117 | |
| 138 | K | A | -2.8595 | |
| 139 | L | A | 0.0000 | |
| 140 | K | A | -1.9944 | |
| 141 | I | A | -0.0545 | |
| 142 | K | A | -0.9854 | |
| 143 | A | A | 0.0000 | |
| 144 | Q | A | -1.2439 | |
| 145 | S | A | -0.7431 | |
| 146 | Y | A | -0.7715 | |
| 147 | L | A | -1.6742 | |
| 148 | D | A | -2.3054 | |
| 149 | A | A | -1.0340 | |
| 150 | I | A | -0.5300 | |
| 151 | Q | A | -1.4317 | |
| 10 | S | B | 0.5571 | |
| 11 | I | B | 1.7948 | |
| 12 | S | B | 0.8335 | |
| 13 | T | B | 0.4857 | |
| 14 | A | B | 0.2676 | |
| 15 | V | B | 0.0000 | |
| 16 | I | B | 0.3249 | |
| 17 | D | B | -1.3183 | |
| 18 | A | B | 0.0000 | |
| 19 | I | B | 0.0000 | |
| 20 | N | B | -2.2218 | |
| 21 | S | B | -1.5565 | |
| 22 | G | B | -1.4833 | |
| 23 | A | B | -0.8188 | |
| 24 | T | B | -0.5595 | |
| 25 | L | B | 0.0000 | |
| 26 | K | B | -0.9991 | |
| 27 | D | B | -1.5229 | |
| 28 | I | B | 0.1012 | |
| 29 | N | B | -0.6737 | |
| 30 | A | B | -0.9143 | |
| 31 | I | B | 0.0000 | |
| 32 | P | B | -2.2429 | |
| 33 | D | B | -3.6298 | |
| 34 | D | B | -3.9069 | |
| 35 | M | B | -2.7336 | |
| 36 | M | B | 0.0000 | |
| 37 | D | B | -3.6450 | |
| 38 | D | B | -3.1035 | |
| 39 | I | B | 0.0000 | |
| 40 | Y | B | -1.2250 | |
| 41 | S | B | -0.8956 | |
| 42 | Y | B | -0.7294 | |
| 43 | A | B | 0.0000 | |
| 44 | Y | B | -0.1710 | |
| 45 | D | B | -1.9788 | |
| 46 | F | B | -2.0956 | |
| 47 | Y | B | -1.8101 | |
| 48 | N | B | -2.5369 | |
| 49 | K | B | -3.1693 | |
| 50 | G | B | -2.7018 | |
| 51 | R | B | -3.2665 | |
| 52 | I | B | -2.1430 | |
| 53 | E | B | -2.3768 | |
| 54 | E | B | -1.7421 | |
| 55 | A | B | 0.0000 | |
| 56 | E | B | -1.0939 | |
| 57 | V | B | 0.0000 | |
| 58 | F | B | 0.0000 | |
| 59 | F | B | 0.0000 | |
| 60 | R | B | -0.2537 | |
| 61 | F | B | 0.0000 | |
| 62 | L | B | 0.0000 | |
| 63 | C | B | 0.0000 | |
| 64 | I | B | 0.1825 | |
| 65 | Y | B | 0.0000 | |
| 66 | D | B | 0.0000 | |
| 67 | F | B | 0.0000 | |
| 68 | Y | B | -0.0852 | |
| 69 | N | B | -0.6538 | |
| 70 | V | B | -0.6551 | |
| 71 | D | B | -1.6040 | |
| 72 | Y | B | 0.0000 | |
| 73 | I | B | 0.0000 | |
| 74 | M | B | -0.3703 | |
| 75 | G | B | -0.1352 | |
| 76 | L | B | 0.0000 | |
| 77 | A | B | 0.0000 | |
| 78 | A | B | 0.0889 | |
| 79 | I | B | 0.0000 | |
| 80 | Y | B | 0.0000 | |
| 81 | Q | B | -0.7038 | |
| 82 | I | B | 0.6044 | |
| 83 | K | B | -0.8280 | |
| 84 | E | B | -2.0631 | |
| 85 | Q | B | -1.5450 | |
| 86 | F | B | -1.6543 | |
| 87 | Q | B | -2.1969 | |
| 88 | Q | B | -1.9795 | |
| 89 | A | B | 0.0000 | |
| 90 | A | B | -1.3587 | |
| 91 | D | B | -2.3447 | |
| 92 | L | B | 0.0000 | |
| 93 | Y | B | 0.0000 | |
| 94 | A | B | -0.5089 | |
| 95 | V | B | 0.0000 | |
| 96 | A | B | 0.0000 | |
| 97 | F | B | -0.7305 | |
| 98 | A | B | -0.6070 | |
| 99 | L | B | -0.6899 | |
| 100 | G | B | -1.8761 | |
| 101 | K | B | -2.6241 | |
| 102 | N | B | -3.1831 | |
| 103 | D | B | -3.2726 | |
| 104 | Y | B | 0.0000 | |
| 105 | T | B | -0.8976 | |
| 106 | P | B | 0.0000 | |
| 107 | V | B | 0.0000 | |
| 108 | F | B | 0.0000 | |
| 109 | H | B | -0.2756 | |
| 110 | T | B | -0.8471 | |
| 111 | G | B | 0.0000 | |
| 112 | Q | B | -0.7304 | |
| 113 | C | B | 0.0000 | |
| 114 | Q | B | -1.4239 | |
| 115 | L | B | -1.0808 | |
| 116 | R | B | -2.5223 | |
| 117 | L | B | -1.8047 | |
| 118 | K | B | -1.9754 | |
| 119 | A | B | -1.0038 | |
| 120 | P | B | -0.8276 | |
| 121 | L | B | -0.0108 | |
| 122 | K | B | -1.6588 | |
| 123 | A | B | 0.0000 | |
| 124 | K | B | -1.9171 | |
| 125 | E | B | -2.5682 | |
| 126 | C | B | 0.0000 | |
| 127 | F | B | 0.0000 | |
| 128 | E | B | -2.8749 | |
| 129 | L | B | -1.4787 | |
| 130 | V | B | 0.0000 | |
| 131 | I | B | -1.6846 | |
| 132 | Q | B | -1.8936 | |
| 133 | H | B | -2.2979 | |
| 134 | S | B | 0.0000 | |
| 135 | N | B | -3.3179 | |
| 136 | D | B | -3.3685 | |
| 137 | E | B | -3.2923 | |
| 138 | K | B | -2.8471 | |
| 139 | L | B | -1.8871 | |
| 140 | K | B | -1.9568 | |
| 141 | I | B | -0.1520 | |
| 142 | K | B | -1.2685 | |
| 143 | A | B | 0.0000 | |
| 144 | Q | B | -1.3476 | |
| 145 | S | B | -0.8390 | |
| 146 | Y | B | -0.9518 | |
| 147 | L | B | 0.0000 | |
| 148 | D | B | -2.2372 | |
| 149 | A | B | -1.0418 | |
| 150 | I | B | -0.7462 | |
| 151 | Q | B | -1.2916 | |
| 63 | L | Q | 2.1208 | |
| 64 | I | Q | 1.6606 | |
| 65 | P | Q | 0.0000 | |
| 66 | E | Q | -1.7381 | |
| 67 | L | Q | -1.5636 | |
| 68 | K | Q | -2.2715 | |
| 69 | A | Q | -1.5986 | |
| 70 | P | Q | -1.6628 | |
| 71 | K | Q | -2.5682 | |
| 72 | S | Q | -2.0484 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine