Project name: sona

Status: done

submitted: 2018-01-03 09:17:24, status changed: 2018-01-03 09:32:05
Settings
Chain sequence(s) A: AKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKLDARKIREILIKAKK
Distance of aggregation 10 Å
Dynamic mode No
Show buried residues

Minimal score value
-3.5045
Maximal score value
2.0754
Average score
-0.7218
Total score value
-377.5011

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
4 A A -0.8234
5 K A -1.8571
6 N A -1.1422
7 I A -0.9437
8 K A 0.0000
9 K A -2.1869
10 G A -1.0511
11 P A -0.3066
12 A A 0.2841
13 P A 1.2015
14 F A 2.0754
15 Y A 1.1292
16 P A 0.2342
17 L A -0.2331
18 E A -1.7790
19 D A -2.3932
20 G A -1.7557
21 T A 0.0000
22 A A 0.0000
23 G A 0.0000
24 E A -0.8255
25 Q A -1.1353
26 L A 0.0000
27 H A 0.0000
28 K A -1.6497
29 A A 0.0000
30 M A 0.0000
31 K A -0.9953
32 R A -1.3276
33 Y A 0.1552
34 A A 0.0000
35 L A 1.7352
36 V A 2.0004
37 P A 0.7416
38 G A -0.0235
39 T A 0.1224
40 I A -0.2052
41 A A 0.0000
42 F A 0.0000
43 T A 0.0000
44 D A 0.0000
45 A A 0.0000
46 H A 0.2007
47 I A 1.2677
48 E A -0.4729
49 V A 0.6614
50 N A -0.2749
51 I A -0.1964
52 T A -0.3801
53 Y A 0.0000
54 A A -0.4059
55 E A -1.5237
56 Y A 0.0000
57 F A 0.0000
58 E A -1.3638
59 M A 0.0000
60 S A 0.0000
61 V A 0.0000
62 R A -1.0753
63 L A 0.0000
64 A A 0.0000
65 E A 0.0000
66 A A 0.0000
67 M A 0.0000
68 K A -2.2099
69 R A -2.3790
70 Y A -1.1891
71 G A -1.4522
72 L A 0.0000
73 N A -1.8824
74 T A -1.4330
75 N A -1.7047
76 H A -1.3493
77 R A -0.9119
78 I A 0.0000
79 V A 0.0000
80 V A 0.0000
81 C A 0.0000
82 S A 0.0000
83 E A -0.4433
84 N A 0.0000
85 S A -0.1614
86 L A 0.0000
87 Q A -0.3383
88 F A 0.0000
89 F A 0.0000
90 M A 0.0000
91 P A 0.0000
92 V A 0.0000
93 L A 0.0000
94 G A 0.0000
95 A A 0.0000
96 L A 0.0000
97 F A 0.0000
98 I A 0.0000
99 G A 0.0000
100 V A 0.0000
101 A A 0.0000
102 V A 0.0000
103 A A 0.0000
104 P A 0.0000
105 A A 0.0000
106 N A -0.2369
107 D A -0.1701
108 I A 1.2270
109 Y A -0.6008
110 N A -2.1246
111 E A -2.9303
112 R A -3.3281
113 E A -2.0791
114 L A 0.0000
115 L A -2.0779
116 N A -1.1918
117 S A 0.0000
118 M A 0.0000
119 N A -1.6336
120 I A -0.8055
121 S A 0.0000
122 Q A -0.6635
123 P A 0.0000
124 T A 0.0000
125 V A 0.0000
126 V A 0.0000
127 F A 0.0000
128 V A 0.0000
129 S A 0.0000
130 K A -1.8950
131 K A -2.4273
132 G A 0.0000
133 L A 0.0000
134 Q A -1.8932
135 K A -1.9568
136 I A 0.0000
137 L A -1.1980
138 N A -1.9351
139 V A 0.0000
140 Q A -2.0318
141 K A -2.6767
142 K A -2.7616
143 L A 0.0000
144 P A -1.1249
145 I A -0.5250
146 I A 0.0000
147 Q A -1.2728
148 K A -0.8334
149 I A 0.0000
150 I A 0.0000
151 I A 0.0000
152 M A 0.0000
153 D A -1.1740
154 S A -1.4940
155 K A -2.1310
156 T A -1.8552
157 D A -2.3668
158 Y A -1.6715
159 Q A -1.6952
160 G A -1.2861
161 F A -0.8423
162 Q A -1.2526
163 S A 0.0000
164 M A 0.0000
165 Y A -0.6377
166 T A -0.7372
167 F A 0.0000
168 V A 0.0000
169 T A -0.2582
170 S A -0.4700
171 H A -1.0134
172 L A -0.8266
173 P A -0.7088
174 P A -0.5521
175 G A -0.7543
176 F A -0.9331
177 N A -1.8417
178 E A -1.2573
179 Y A -0.6297
180 D A -1.5410
181 F A 0.0000
182 V A 0.8557
183 P A -0.1572
184 E A -1.0041
185 S A -0.7323
186 F A -1.1679
187 D A -2.0829
188 R A -2.2326
189 D A -2.6135
190 K A -2.6812
191 T A -1.6392
192 I A -0.7407
193 A A 0.0000
194 L A 0.0000
195 I A 0.0000
196 M A 0.0000
197 N A -0.6379
198 S A -0.2907
204 L A 1.2306
205 P A 0.1970
206 K A -0.4536
207 G A 0.0000
208 V A 0.0000
209 A A 0.0000
210 L A 0.0000
211 P A 0.0000
212 H A 0.0000
213 R A -1.4704
214 T A 0.0000
215 A A 0.0000
216 C A 0.0000
217 V A 0.0000
218 R A 0.0000
219 F A 0.0000
220 S A 0.0000
221 H A 0.0000
222 A A 0.0000
223 R A 0.0000
224 D A 0.0000
225 P A -0.0550
226 I A 0.0772
227 F A 0.0000
228 G A -0.4306
229 N A -0.4606
230 Q A -0.1182
231 I A 0.6680
232 I A 1.3808
233 P A -0.1859
234 D A -1.5441
235 T A 0.0000
236 A A 0.0000
237 I A 0.0000
238 L A 0.0000
239 S A 0.0000
240 V A 0.0570
241 V A 0.0000
242 P A -0.2192
243 F A 0.0000
244 H A -0.6307
245 H A -0.8353
246 G A -0.3672
247 F A -0.0196
248 G A 0.0000
249 M A 0.0000
250 F A 0.0000
251 T A 0.0199
252 T A 0.0000
253 L A 0.0000
254 G A 0.0000
255 Y A 0.0000
256 L A 0.0000
257 I A 0.0000
258 C A 0.0000
259 G A -0.2313
260 F A 0.0000
261 R A -0.7092
262 V A 0.0000
263 V A 0.0000
264 L A 0.0000
265 M A 0.0000
266 Y A -0.5209
267 R A -1.6913
268 F A -1.0068
269 E A -1.9816
270 E A -1.9163
271 E A -2.4361
272 L A -1.8968
273 F A 0.0000
274 L A 0.0000
275 R A -3.1010
276 S A 0.0000
277 L A 0.0000
278 Q A -2.4051
279 D A -2.0672
280 Y A -1.3217
281 K A -2.3052
282 I A 0.0000
283 Q A -1.2938
284 S A 0.0000
285 A A 0.0000
286 L A 0.0000
287 L A 0.0000
288 V A 0.5701
289 P A 0.2152
290 T A 0.2940
291 L A 0.3780
292 F A 0.0000
293 S A -0.1935
294 F A 0.1581
295 F A 0.0000
296 A A -1.4702
297 K A -1.5832
298 S A 0.0000
299 T A -1.0675
300 L A -1.3664
301 I A 0.0000
302 D A -3.0359
303 K A -2.9980
304 Y A -2.7951
305 D A -3.0763
306 L A -2.2932
307 S A -1.3156
308 N A -1.5348
309 L A 0.0000
310 H A -1.4149
311 E A -0.8797
312 I A 0.0000
313 A A 0.0000
314 S A 0.0000
315 G A -0.0664
316 G A -0.0552
317 A A 0.0005
318 P A -0.1637
319 L A -0.7069
320 S A -1.5709
321 K A -2.7579
322 E A -3.0158
323 V A -1.7013
324 G A 0.0000
325 E A -3.5045
326 A A -2.6663
327 V A 0.0000
328 A A 0.0000
329 K A -2.9993
330 R A -2.7562
331 F A 0.0000
332 H A -2.3985
333 L A -1.5456
334 P A -1.2624
335 G A -1.6120
336 I A -0.8174
337 R A -0.5121
338 Q A 0.0000
339 G A 0.0000
340 Y A 0.0000
341 G A -0.0026
342 L A 0.2074
343 T A -0.1437
344 E A 0.0000
345 T A 0.0000
346 T A 0.0000
347 S A -0.0591
348 A A 0.0000
349 I A 0.0000
350 L A 0.0000
351 I A 0.0000
352 T A -0.6600
353 P A -0.9565
354 E A -1.8215
355 G A -1.2629
359 P A -1.1348
360 G A -1.1153
361 A A -0.4056
362 V A 0.0000
363 G A 0.0000
364 K A -1.2206
365 V A 0.0000
366 V A 0.0000
367 P A 0.0000
368 F A 0.0783
369 F A 0.0000
370 E A -1.0787
371 A A 0.0000
372 K A -0.9359
373 V A 0.0000
374 V A 0.0000
375 D A -2.0527
376 L A -1.5688
377 D A -2.1438
378 T A -1.6741
379 G A -1.7848
380 K A -2.2811
381 T A -1.2380
382 L A 0.0000
383 G A -1.1651
384 V A -1.1285
385 N A -1.8684
386 Q A -1.9976
387 R A -2.0679
388 G A 0.0000
389 E A -1.0636
390 L A 0.0000
391 C A 0.0000
392 V A 0.0000
393 R A -1.1201
394 G A -0.4485
395 P A -0.3090
396 M A 0.0000
397 I A 0.0000
398 M A 0.0000
399 S A -0.5221
400 G A 0.0000
401 Y A -0.9059
402 V A -0.6057
403 N A -1.6509
404 N A -1.8135
405 P A -1.9331
406 E A -2.6071
407 A A -1.5424
408 T A -1.4700
409 N A -2.2766
410 A A -1.2456
411 L A -0.6544
412 I A -1.2410
413 D A -2.2926
414 K A -3.0483
415 D A -2.8969
416 G A -1.9938
417 W A 0.0000
418 L A 0.0000
419 H A -0.7075
420 S A -0.4318
421 G A -1.0324
422 D A -0.6789
423 I A 0.0206
424 A A 0.0000
425 Y A -0.7313
426 W A 0.0000
427 D A -2.1524
428 E A -3.0220
429 D A -3.0834
430 E A -2.5364
431 H A -1.7894
432 F A 0.0000
433 F A 0.0984
434 I A 0.6824
435 V A 0.8064
441 L A 1.0458
442 I A 0.0000
443 K A -1.6858
444 Y A 0.0000
445 K A -2.7619
446 G A -1.4768
447 Y A -0.4519
448 Q A -1.1175
449 V A 0.0000
450 A A -0.5370
451 P A -0.5156
452 A A -0.6712
453 E A -1.8122
454 L A 0.0000
455 E A -0.8267
456 S A -0.8247
457 I A -0.6395
458 L A 0.0000
459 L A 0.0686
460 Q A -0.8123
461 H A -0.4501
462 P A -0.4988
463 N A -0.7276
464 I A 0.0000
465 F A 0.4917
466 D A -0.2380
467 A A 0.0000
468 G A 0.0000
469 V A 0.0000
470 A A 0.0000
471 G A 0.0000
472 L A 0.0000
473 P A -1.4671
474 D A -2.6568
475 D A -3.3944
476 D A -3.3050
477 A A 0.0000
478 G A -2.8461
479 E A -2.3708
480 L A -1.8733
481 P A 0.0000
482 A A 0.0000
483 A A 0.0000
484 V A 0.0000
485 V A 0.0000
486 V A 0.0000
487 L A -0.3897
488 E A -0.8836
489 H A -1.3931
490 G A -1.4582
491 K A -1.3650
492 T A -0.7988
493 M A 0.0000
494 T A -1.2622
495 E A -1.6064
496 K A -2.9552
497 E A -2.8236
498 I A 0.0000
499 V A -2.1881
500 D A -3.0836
501 Y A -1.6487
502 V A 0.0000
503 A A -1.6412
504 S A -1.1914
505 Q A -1.4952
506 V A -0.9183
507 T A -0.5852
508 T A -0.6513
509 A A -1.0561
510 K A -1.6466
511 K A -1.8280
512 L A 0.0000
513 R A -2.2653
514 G A 0.0000
515 G A 0.0000
516 V A 0.0000
517 V A 0.4352
518 F A 0.6922
519 V A -0.5261
520 D A -2.1327
521 E A -2.2543
522 V A -1.4462
523 P A -1.7411
529 K A -1.7871
530 L A -1.2237
531 D A -2.7243
532 A A -2.3506
533 R A -3.4358
534 K A -3.3188
535 I A 0.0000
536 R A -2.7757
537 E A -3.4977
538 I A -1.7346
539 L A 0.0000
540 I A -1.5757
541 K A -2.2668
542 A A -1.1601
543 K A -1.5136
544 K A -2.2540

 

Laboratory of Theory of Biopolymers 2015