Project name: 2J8Z

Chain sequence(s)	A: QSMLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.2879
• Maximal score value: 2.3219
• Average score: -0.6208
• Total score value: -204.2421

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
0	Q	A	-1.4888
1	S	A	-1.1952
2	M	A	0.0000
3	L	A	-0.5656
4	A	A	0.0000
5	V	A	0.0000
6	H	A	-1.0949
7	F	A	-1.9425
8	D	A	-2.6797
9	K	A	-3.0423
10	P	A	-2.5558
11	G	A	-2.0254
12	G	A	-1.8295
13	P	A	0.0000
14	E	A	-2.4863
15	N	A	-2.3310
16	L	A	0.0000
17	Y	A	-0.4943
18	V	A	-0.3588
19	K	A	-1.2738
20	E	A	-2.0735
21	V	A	-0.9696
22	A	A	-0.6751
23	K	A	-0.7924
24	P	A	-0.4810
25	S	A	-0.7636
26	P	A	-1.0920
27	G	A	-1.4110
28	E	A	-2.1742
29	G	A	-1.2937
30	E	A	-1.2696
31	V	A	0.0000
32	L	A	0.0000
33	L	A	0.0000
34	K	A	-1.0096
35	V	A	0.0000
36	A	A	0.0000
37	A	A	0.0000
38	S	A	0.0000
39	A	A	0.0000
40	L	A	0.0000
41	N	A	0.0000
42	R	A	-0.6187
43	A	A	0.0000
44	D	A	0.0000
45	L	A	0.0000
46	M	A	-1.1050
47	Q	A	0.0000
48	R	A	0.0000
49	Q	A	-2.2423
50	G	A	-2.2858
51	Q	A	-2.0384
52	Y	A	-1.5026
53	D	A	-2.4393
54	P	A	-1.5220
55	P	A	-1.2296
56	P	A	-0.9587
57	G	A	-0.7902
58	A	A	-0.8498
59	S	A	-0.8015
60	N	A	-1.6072
61	I	A	-0.3738
62	L	A	0.0000
63	G	A	0.0000
64	L	A	0.0000
65	E	A	0.0000
66	A	A	0.0000
67	S	A	0.0000
68	G	A	0.0000
69	H	A	-0.5527
70	V	A	0.0000
71	A	A	-0.5407
72	E	A	-1.0628
73	L	A	-0.4626
74	G	A	-1.1213
75	P	A	-0.9854
76	G	A	-0.7864
77	C	A	-0.3638
80	H	A	-1.2618
81	W	A	-0.9487
82	K	A	-1.1899
83	I	A	0.5313
84	G	A	-0.4719
85	D	A	-0.5398
86	T	A	-0.2870
87	A	A	0.0000
88	M	A	0.0000
89	A	A	0.0000
90	L	A	0.0000
91	L	A	0.0000
92	P	A	-0.7305
93	G	A	0.0000
94	G	A	0.0000
95	G	A	0.0000
96	Q	A	0.0000
97	A	A	0.0000
98	Q	A	-0.6674
99	Y	A	-0.4332
100	V	A	0.0000
101	T	A	-0.5081
102	V	A	0.0000
103	P	A	-0.9129
104	E	A	-0.7455
105	G	A	-1.0801
106	L	A	0.0000
107	L	A	0.0000
108	M	A	0.0000
109	P	A	-0.3264
110	I	A	-0.3574
111	P	A	0.0000
112	E	A	-2.0086
113	G	A	-1.2370
114	L	A	-0.4123
115	T	A	-0.1946
116	L	A	0.1782
117	T	A	0.1901
118	Q	A	0.2355
119	A	A	0.0000
120	A	A	0.0000
121	A	A	0.0000
122	I	A	0.0000
123	P	A	0.0000
124	E	A	-0.1674
125	A	A	0.0000
126	W	A	0.0000
127	L	A	0.0000
128	T	A	0.0000
129	A	A	0.0000
130	F	A	0.0000
131	Q	A	0.0000
132	L	A	0.0000
133	L	A	0.0000
134	H	A	-0.4052
135	L	A	0.4708
136	V	A	0.2973
137	G	A	0.0000
138	N	A	-1.3140
139	V	A	-1.0114
140	Q	A	-1.5424
141	A	A	-0.8609
142	G	A	-0.7973
143	D	A	0.0000
144	Y	A	0.2496
145	V	A	0.0000
146	L	A	0.0000
147	I	A	0.0000
148	H	A	0.0000
149	A	A	0.0840
150	G	A	0.0000
151	L	A	0.0000
152	S	A	-0.3845
153	G	A	0.0000
154	V	A	0.0847
155	G	A	0.0000
156	T	A	0.0000
157	A	A	0.0000
158	A	A	0.0000
159	I	A	0.0000
160	Q	A	0.0000
161	L	A	0.0000
162	T	A	0.0000
163	R	A	-1.4036
164	M	A	-0.9105
165	A	A	-0.6727
166	G	A	-0.8319
167	A	A	0.0000
168	I	A	-0.1115
169	P	A	0.0000
170	L	A	0.0000
171	V	A	0.0000
172	T	A	0.0000
173	A	A	0.0000
174	G	A	-1.5340
175	S	A	-2.2212
176	Q	A	-2.7380
177	K	A	-2.8851
178	K	A	-2.3628
179	L	A	-2.1487
180	Q	A	-3.0564
181	M	A	-2.2118
182	A	A	0.0000
183	E	A	-3.0065
184	K	A	-2.8017
185	L	A	-1.4272
186	G	A	-1.5458
187	A	A	0.0000
188	A	A	-0.5912
189	A	A	0.0000
190	G	A	-0.7530
191	F	A	0.0000
192	N	A	0.0000
193	Y	A	-1.4589
194	K	A	-2.8939
195	K	A	-3.2879
196	E	A	-3.0368
197	D	A	-2.6539
198	F	A	0.0000
199	S	A	0.0000
200	E	A	-2.7895
201	A	A	-1.8899
202	T	A	0.0000
203	L	A	-1.6316
204	K	A	-2.3924
205	F	A	-0.8087
206	T	A	0.0000
207	K	A	-2.1749
208	G	A	-1.7002
209	A	A	-0.5019
210	G	A	0.0000
211	V	A	0.0000
212	N	A	-0.5867
213	L	A	0.0000
214	I	A	0.0000
215	L	A	0.0000
216	D	A	0.0000
217	C	A	0.0000
218	I	A	0.9403
219	G	A	0.0000
220	G	A	0.0000
221	S	A	-0.7119
222	Y	A	-0.4154
223	W	A	0.0000
224	E	A	-2.5098
225	K	A	-2.2511
226	N	A	0.0000
227	V	A	0.0000
228	N	A	-1.7907
229	C	A	0.0000
230	L	A	0.0000
231	A	A	0.0000
232	L	A	0.2039
233	D	A	-1.4961
234	G	A	0.0000
235	R	A	-0.7440
236	W	A	0.0000
237	V	A	0.0000
238	L	A	0.9748
239	Y	A	1.0590
240	G	A	1.0710
241	L	A	1.4913
242	M	A	1.2526
243	G	A	0.2844
244	G	A	-0.1615
245	G	A	-0.7127
246	D	A	-1.9313
247	I	A	-1.2924
248	N	A	-1.8159
249	G	A	-1.1985
250	P	A	-0.1204
251	L	A	0.7329
252	F	A	2.3219
253	S	A	1.3895
254	K	A	0.4475
255	L	A	1.0296
256	L	A	1.9704
257	F	A	2.0842
258	K	A	0.2184
259	R	A	-0.9437
260	G	A	-0.2941
261	S	A	-0.1837
262	L	A	0.8199
263	I	A	0.8767
264	T	A	0.7353
265	S	A	0.0000
266	L	A	0.8587
267	L	A	0.0000
268	R	A	0.0000
269	S	A	-0.8376
270	R	A	-1.8825
271	D	A	-2.9667
272	N	A	-2.7741
273	K	A	-2.7112
274	Y	A	-1.7411
275	K	A	0.0000
276	Q	A	-1.6508
277	M	A	-0.6850
278	L	A	0.0000
279	V	A	0.0000
280	N	A	-1.6786
281	A	A	-1.3029
282	F	A	0.0000
283	T	A	-1.7039
284	E	A	-2.7570
285	Q	A	-2.3215
286	I	A	0.0000
287	L	A	0.0000
288	P	A	-1.4470
289	H	A	-1.4194
290	F	A	0.0000
291	S	A	-1.2812
292	T	A	-1.3399
296	Q	A	-2.1695
297	R	A	-2.2823
298	L	A	0.0000
299	L	A	0.3851
300	P	A	0.0000
301	V	A	0.0000
302	L	A	0.0301
303	D	A	-0.8836
304	R	A	-1.0405
305	I	A	0.3328
306	Y	A	-0.4879
307	P	A	-0.6581
308	V	A	0.0000
309	T	A	-0.9266
310	E	A	-1.7655
311	I	A	0.0000
312	Q	A	-2.1596
313	E	A	-2.7051
314	A	A	0.0000
315	H	A	0.0000
316	K	A	-2.6391
317	Y	A	-1.9433
318	M	A	0.0000
319	E	A	-2.1165
320	A	A	-1.6857
321	N	A	-2.2216
322	K	A	-2.6184
323	N	A	0.0000
324	I	A	0.0000
325	G	A	0.0000
326	K	A	0.0000
327	I	A	0.0000
328	V	A	0.0000
329	L	A	0.0000
330	E	A	-0.8966
331	L	A	0.0000
332	P	A	-0.9588
333	Q	A	-1.4148