Project name: 5nhw:L
Status: done
submitted: 2019-03-21 13:06:39, status changed: 2019-03-21 13:18:15
Settings
Chain sequence(s)
|
L: SALTQPASVSGSPGQSITISCTGTSSDVGSYNYVNWYQQHPGKAPKLMIYGVSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCGTFAGGSYYGVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTEA
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.1844
-
Maximal score value
-
1.8546
-
Average score
-
-0.6954
-
Total score value
-
-149.5097
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
2 |
S |
L |
0.1207 |
|
3 |
A |
L |
0.2446 |
|
4 |
L |
L |
0.0000 |
|
5 |
T |
L |
-0.0684 |
|
6 |
Q |
L |
-0.2066 |
|
7 |
P |
L |
-0.3302 |
|
8 |
A |
L |
-0.5172 |
|
9 |
S |
L |
-0.6188 |
|
10 |
V |
L |
-0.3013 |
|
11 |
S |
L |
-0.6885 |
|
12 |
G |
L |
0.0000 |
|
13 |
S |
L |
-0.8738 |
|
14 |
P |
L |
-1.1991 |
|
15 |
G |
L |
-1.4566 |
|
16 |
Q |
L |
-1.7594 |
|
17 |
S |
L |
-1.0113 |
|
18 |
I |
L |
-0.2796 |
|
19 |
T |
L |
-0.0412 |
|
20 |
I |
L |
0.0000 |
|
21 |
S |
L |
-0.2262 |
|
22 |
C |
L |
0.0000 |
|
23 |
T |
L |
-0.4766 |
|
24 |
G |
L |
-0.4929 |
|
25 |
T |
L |
-0.6070 |
|
26 |
S |
L |
-0.6851 |
|
27 |
S |
L |
-0.4733 |
|
28 |
D |
L |
0.0000 |
|
29 |
V |
L |
0.0000 |
|
30 |
G |
L |
-1.0243 |
|
31 |
S |
L |
-0.5652 |
|
32 |
Y |
L |
-0.1273 |
|
33 |
N |
L |
-1.0099 |
|
34 |
Y |
L |
0.0000 |
|
35 |
V |
L |
0.0000 |
|
36 |
N |
L |
0.0000 |
|
37 |
W |
L |
0.0000 |
|
38 |
Y |
L |
0.0506 |
|
39 |
Q |
L |
0.0000 |
|
40 |
Q |
L |
-1.5237 |
|
41 |
H |
L |
-1.8073 |
|
42 |
P |
L |
-1.3394 |
|
43 |
G |
L |
-1.5078 |
|
44 |
K |
L |
-2.3392 |
|
45 |
A |
L |
-1.4188 |
|
46 |
P |
L |
-1.3376 |
|
47 |
K |
L |
-1.4483 |
|
48 |
L |
L |
-0.2305 |
|
49 |
M |
L |
0.0000 |
|
50 |
I |
L |
0.0000 |
|
51 |
Y |
L |
-0.5425 |
|
52 |
G |
L |
-0.8254 |
|
53 |
V |
L |
0.0000 |
|
54 |
S |
L |
-1.6170 |
|
55 |
K |
L |
-2.3032 |
|
56 |
R |
L |
-2.1194 |
|
57 |
P |
L |
-0.9678 |
|
58 |
S |
L |
-0.8630 |
|
59 |
G |
L |
-0.8457 |
|
60 |
V |
L |
-1.0589 |
|
61 |
S |
L |
-1.0867 |
|
62 |
N |
L |
-1.7435 |
|
63 |
R |
L |
-1.2210 |
|
64 |
F |
L |
0.0000 |
|
65 |
S |
L |
-1.1533 |
|
66 |
G |
L |
-0.9012 |
|
67 |
S |
L |
-0.9812 |
|
68 |
K |
L |
-1.1569 |
|
69 |
S |
L |
-0.8780 |
|
70 |
G |
L |
-1.0762 |
|
71 |
N |
L |
-1.0446 |
|
72 |
T |
L |
-0.7763 |
|
73 |
A |
L |
0.0000 |
|
74 |
S |
L |
-0.4082 |
|
75 |
L |
L |
0.0000 |
|
76 |
T |
L |
-0.2434 |
|
77 |
I |
L |
0.0000 |
|
78 |
S |
L |
-1.1188 |
|
79 |
G |
L |
-1.1912 |
|
80 |
L |
L |
0.0000 |
|
81 |
Q |
L |
-1.8097 |
|
82 |
A |
L |
-1.5517 |
|
83 |
E |
L |
-2.3107 |
|
84 |
D |
L |
0.0000 |
|
85 |
E |
L |
-1.8699 |
|
86 |
A |
L |
0.0000 |
|
87 |
D |
L |
-1.0049 |
|
88 |
Y |
L |
0.0000 |
|
89 |
Y |
L |
0.2088 |
|
90 |
C |
L |
0.0000 |
|
91 |
G |
L |
0.0000 |
|
92 |
T |
L |
0.0000 |
|
93 |
F |
L |
1.6067 |
|
94 |
A |
L |
0.9021 |
|
95 |
G |
L |
0.0545 |
|
96 |
G |
L |
-0.2060 |
|
97 |
S |
L |
0.1562 |
|
98 |
Y |
L |
1.1301 |
|
99 |
Y |
L |
1.5037 |
|
100 |
G |
L |
1.1869 |
|
101 |
V |
L |
1.5079 |
|
102 |
F |
L |
1.8546 |
|
103 |
G |
L |
0.0000 |
|
104 |
G |
L |
-0.0304 |
|
105 |
G |
L |
-0.2431 |
|
106 |
T |
L |
0.0000 |
|
107 |
K |
L |
-1.1056 |
|
108 |
L |
L |
0.0000 |
|
109 |
T |
L |
0.0000 |
|
110 |
V |
L |
0.0000 |
|
111 |
L |
L |
-0.7588 |
|
112 |
G |
L |
-0.9800 |
|
113 |
Q |
L |
-1.2658 |
|
114 |
P |
L |
-1.3540 |
|
115 |
K |
L |
-2.2882 |
|
116 |
A |
L |
-1.3470 |
|
117 |
A |
L |
-0.8056 |
|
118 |
P |
L |
-0.3112 |
|
119 |
S |
L |
-0.1496 |
|
120 |
V |
L |
0.0475 |
|
121 |
T |
L |
0.5709 |
|
122 |
L |
L |
0.9240 |
|
123 |
F |
L |
1.7222 |
|
124 |
P |
L |
0.6899 |
|
125 |
P |
L |
0.0000 |
|
126 |
S |
L |
-1.0451 |
|
127 |
S |
L |
-1.6728 |
|
128 |
E |
L |
-2.8764 |
|
129 |
E |
L |
-2.5204 |
|
130 |
L |
L |
-2.4491 |
|
131 |
Q |
L |
-2.6577 |
|
132 |
A |
L |
-2.2395 |
|
133 |
N |
L |
-2.9475 |
|
134 |
K |
L |
-3.0925 |
|
135 |
A |
L |
0.0000 |
|
136 |
T |
L |
-0.0993 |
|
137 |
L |
L |
0.0000 |
|
138 |
V |
L |
1.1489 |
|
139 |
C |
L |
0.0000 |
|
140 |
L |
L |
1.0567 |
|
141 |
I |
L |
0.0000 |
|
142 |
S |
L |
-0.5487 |
|
143 |
D |
L |
-1.5745 |
|
144 |
F |
L |
0.0000 |
|
145 |
Y |
L |
0.0000 |
|
146 |
P |
L |
0.0000 |
|
147 |
G |
L |
-1.0523 |
|
148 |
A |
L |
-0.3322 |
|
149 |
V |
L |
-0.0822 |
|
150 |
T |
L |
-0.1076 |
|
151 |
V |
L |
0.2186 |
|
152 |
A |
L |
-0.3412 |
|
153 |
W |
L |
0.0000 |
|
154 |
K |
L |
-0.8292 |
|
155 |
A |
L |
0.0000 |
|
156 |
D |
L |
-1.1084 |
|
157 |
S |
L |
-0.7585 |
|
158 |
S |
L |
-0.4837 |
|
159 |
P |
L |
-0.7457 |
|
160 |
V |
L |
-0.7797 |
|
161 |
K |
L |
-1.8162 |
|
162 |
A |
L |
-1.0278 |
|
163 |
G |
L |
-0.9175 |
|
164 |
V |
L |
-0.9681 |
|
165 |
E |
L |
-1.8094 |
|
166 |
T |
L |
-0.7035 |
|
167 |
T |
L |
-0.4615 |
|
168 |
T |
L |
-0.1276 |
|
169 |
P |
L |
-0.5497 |
|
170 |
S |
L |
-1.2670 |
|
171 |
K |
L |
-2.5631 |
|
172 |
Q |
L |
-2.0638 |
|
173 |
S |
L |
-1.6338 |
|
174 |
N |
L |
-2.3248 |
|
175 |
N |
L |
-2.4577 |
|
176 |
K |
L |
-2.2355 |
|
177 |
Y |
L |
-1.4463 |
|
178 |
A |
L |
-0.7025 |
|
179 |
A |
L |
0.0000 |
|
180 |
S |
L |
0.1171 |
|
181 |
S |
L |
0.0000 |
|
182 |
Y |
L |
0.2969 |
|
183 |
L |
L |
0.0000 |
|
184 |
S |
L |
-0.6707 |
|
185 |
L |
L |
-1.1061 |
|
186 |
T |
L |
-1.8791 |
|
187 |
P |
L |
-2.5741 |
|
188 |
E |
L |
-3.1844 |
|
189 |
Q |
L |
-2.3162 |
|
190 |
W |
L |
0.0000 |
|
191 |
K |
L |
-3.0597 |
|
192 |
S |
L |
-2.3900 |
|
193 |
H |
L |
-2.3155 |
|
194 |
R |
L |
-2.4189 |
|
195 |
S |
L |
-1.4139 |
|
196 |
Y |
L |
0.0000 |
|
197 |
S |
L |
0.0000 |
|
198 |
C |
L |
0.0000 |
|
199 |
Q |
L |
-0.5194 |
|
200 |
V |
L |
0.0000 |
|
201 |
T |
L |
-0.5198 |
|
202 |
H |
L |
0.0000 |
|
203 |
E |
L |
-2.2652 |
|
204 |
G |
L |
-1.4436 |
|
205 |
S |
L |
-0.8141 |
|
206 |
T |
L |
-0.4057 |
|
207 |
V |
L |
0.0805 |
|
208 |
E |
L |
-0.9466 |
|
209 |
K |
L |
-0.6573 |
|
210 |
T |
L |
-0.2897 |
|
211 |
V |
L |
0.0609 |
|
212 |
A |
L |
-1.1403 |
|
213 |
P |
L |
-1.3544 |
|
214 |
T |
L |
-1.4974 |
|
215 |
E |
L |
-1.8242 |
|
216 |
A |
L |
-1.0369 |
|