Project name: 2WCV [mutate: EA77Y, EB77Y, EC77Y, ED77Y, EE77Y, EF77Y, EG77Y, EH77Y, EI77Y, EJ77Y]

Status: done

submitted: 2017-09-13 11:07:23, status changed: 2017-09-13 11:56:17
Settings
Chain sequence(s) A: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
C: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
B: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
E: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
D: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
G: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
F: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
I: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
H: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
J: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
Distance of aggregation 10 Å
Dynamic mode No
Mutated residues EA77Y, EB77Y, EC77Y, ED77Y, EE77Y, EF77Y, EG77Y, EH77Y, EI77Y, EJ77Y
Energy difference between WD and mutated (by FoldX) -2.80423 kcal/mol
Show buried residues

Minimal score value
-3.7155
Maximal score value
1.5522
Average score
-0.4965
Total score value
-692.5936

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
1 M A 1.4699
2 L A 1.2603
3 K A -0.6434
4 T A -0.2068
5 I A 0.6701
6 S A 0.3480
7 P A 0.5483
8 L A 0.5338
9 I A 0.0000
10 S A -0.7339
11 P A -1.1126
12 E A -2.4394
13 L A 0.0000
14 L A -1.1468
15 K A -2.4379
16 V A 0.0000
17 L A 0.0000
18 A A -0.8463
19 E A -1.1282
20 M A 0.0000
21 G A 0.0000
22 H A 0.0000
23 G A -0.1127
24 D A 0.0000
25 E A -0.5856
26 I A 0.0000
27 I A 0.0000
28 F A 0.0000
29 S A 0.0000
30 D A 0.0000
31 A A -1.1218
32 H A -0.5910
33 F A 0.0000
34 P A 0.0000
35 A A 0.0000
36 H A -0.5908
37 S A -0.6831
38 M A -1.3013
39 G A -1.3265
40 P A -1.2596
41 Q A -0.9210
42 V A -0.3521
43 I A -0.8164
44 R A -1.2682
45 A A -1.0882
46 D A -2.1028
47 G A -1.4398
48 L A -0.6711
49 L A -0.4332
50 V A 0.0000
51 S A 0.0000
52 D A -0.7999
53 L A 0.0000
54 L A 0.0000
55 Q A -1.5741
56 A A 0.0000
57 I A 0.0000
58 I A -0.0982
59 P A -0.0745
60 L A 0.5163
61 F A 0.0000
62 E A -0.6156
63 L A -0.1599
64 D A 0.0000
65 S A -0.2697
66 Y A 0.0853
67 A A -0.2809
68 P A -0.4045
69 P A 0.0000
70 L A 0.0000
71 V A 0.0000
72 M A 0.0000
73 M A 0.0000
74 A A 0.0893
75 A A -0.3358
76 V A 0.0000
77 Y A -0.2158 mutated: EA77Y
78 G A -0.3130
79 D A -0.2785
80 T A -0.5424
81 L A -0.9936
82 D A -2.4725
83 P A -2.3103
84 E A -3.2420
85 V A 0.0000
86 E A -2.5409
87 R A -3.4238
88 R A -2.6470
89 Y A 0.0000
90 R A -2.8702
91 N A -2.5118
92 A A -1.8539
93 L A 0.0000
94 S A -0.9711
95 L A -0.6458
98 P A -0.0547
99 C A 0.0938
100 P A -0.3758
101 D A -1.4846
102 I A 0.0000
103 I A 0.4423
104 R A -0.0803
105 I A 0.2338
106 N A -0.2957
107 R A -0.0361
108 F A 0.3714
109 A A -0.3537
110 F A 0.0000
111 Y A -1.0121
112 E A -2.3907
113 R A -1.9767
114 A A 0.0000
115 Q A -2.6314
116 K A -2.7481
117 A A 0.0000
118 F A -0.7801
119 A A 0.0000
120 I A 0.0000
121 V A 0.0000
122 I A 0.0000
123 T A 0.0000
124 G A -1.3940
125 E A 0.0000
126 R A -2.0233
127 A A -1.6650
128 K A -1.4008
129 Y A 0.0000
130 G A 0.0000
131 N A 0.0000
132 I A 0.0000
133 L A 0.0000
134 L A 0.0000
135 K A -0.3940
136 K A 0.0000
137 G A 0.0000
138 V A -0.3368
139 T A -0.3938
140 P A -0.6023
1 M B 1.1348
2 L B 0.6132
3 K B -0.9852
4 T B -0.4162
5 I B 0.3374
6 S B 0.1015
7 P B 0.3459
8 L B 0.3711
9 I B 0.0000
10 S B -0.7259
11 P B -1.1244
12 E B -2.3087
13 L B 0.0000
14 L B -1.1400
15 K B -2.3601
16 V B 0.0000
17 L B 0.0000
18 A B -0.6292
19 E B -1.1127
20 M B 0.0000
21 G B 0.0000
22 H B -0.1528
23 G B 0.0437
24 D B 0.0000
25 E B -0.6055
26 I B 0.0000
27 I B 0.0000
28 F B 0.0000
29 S B 0.0000
30 D B 0.0000
31 A B -1.1413
32 H B 0.0000
33 F B 0.0000
34 P B 0.0000
35 A B 0.0000
36 H B -0.6496
37 S B -0.7770
38 M B -0.9071
39 G B -1.2981
40 P B -1.2666
41 Q B -1.0127
42 V B -0.4000
43 I B -0.8385
44 R B -1.2983
45 A B -1.0929
46 D B -2.0780
47 G B -1.3841
48 L B -0.4015
49 L B -0.2879
50 V B 0.0000
51 S B -1.1919
52 D B -0.7924
53 L B 0.0000
54 L B 0.0000
55 Q B -1.6738
56 A B 0.0000
57 I B 0.0000
58 I B 0.0000
59 P B -0.3163
60 L B 0.3338
61 F B 0.0000
62 E B -0.7257
63 L B -0.2177
64 D B 0.0000
65 S B -0.0679
66 Y B 0.3031
67 A B 0.1772
68 P B -0.3458
69 P B 0.0000
70 L B 0.0000
71 V B 0.0000
72 M B 0.0000
73 M B 0.0000
74 A B 0.0000
75 A B 0.0476
76 V B 0.7803
77 Y B 1.5522 mutated: EB77Y
78 G B 0.6534
79 D B 0.3103
80 T B 0.1253
81 L B -0.4989
82 D B -1.6785
83 P B -1.8125
84 E B -2.5843
85 V B 0.0000
86 E B -2.4460
87 R B -3.6020
88 R B -2.7948
89 Y B 0.0000
90 R B -3.1742
91 N B -2.7115
92 A B 0.0000
93 L B 0.0000
94 S B -1.1181
95 L B -0.5062
96 Q B -1.1063
97 A B -0.5519
98 P B -0.9230
99 C B -0.9962
100 P B -1.1384
101 D B -1.9933
102 I B 0.0000
103 I B -0.6720
104 R B -0.5195
105 I B 0.0000
106 N B -0.4237
107 R B -0.1279
108 F B 0.4033
109 A B 0.0000
110 F B 0.0000
111 Y B -0.2217
112 E B 0.0000
113 R B -0.8471
114 A B 0.0000
115 Q B -1.8040
116 K B -2.1561
117 A B 0.0000
118 F B 0.0000
119 A B 0.0000
120 I B 0.0000
121 V B 0.0000
122 I B 0.0000
123 T B 0.0000
124 G B -1.2970
125 E B 0.0000
126 R B -2.0708
127 A B -1.4515
128 K B -1.5110
129 Y B 0.0000
130 G B 0.0000
131 N B 0.0000
132 I B 0.0000
133 L B 0.0000
134 L B 0.0000
135 K B -0.3761
136 K B 0.0000
137 G B 0.0000
138 V B -0.2371
139 T B -0.3823
140 P B -0.5114
1 M C 1.5059
2 L C 1.2916
3 K C -0.6147
4 T C -0.1684
5 I C 0.7261
6 S C 0.4725
7 P C 0.6654
8 L C 0.6669
9 I C 0.0000
10 S C -0.6853
11 P C -1.0894
12 E C -2.3808
13 L C 0.0000
14 L C -1.1490
15 K C -2.4104
16 V C 0.0000
17 L C 0.0000
18 A C -0.8181
19 E C -1.0591
20 M C 0.0000
21 G C 0.0000
22 H C 0.0000
23 G C -0.1906
24 D C 0.0000
25 E C -0.7013
26 I C 0.0000
27 I C 0.0000
28 F C 0.0000
29 S C 0.0000
30 D C 0.0000
31 A C -1.0331
32 H C 0.0000
33 F C 0.0000
34 P C 0.0000
35 A C 0.0000
36 H C -0.5803
37 S C -0.9112
38 M C 0.0000
39 G C -1.4411
40 P C -1.2617
41 Q C -0.7922
42 V C -0.2591
43 I C -0.7384
44 R C -1.2117
45 A C -1.0376
46 D C -2.0574
47 G C -1.2112
48 L C -0.6629
49 L C -0.4690
50 V C 0.0000
51 S C -0.8887
52 D C -0.8556
53 L C 0.0000
54 L C 0.0000
55 Q C -1.3777
56 A C -0.3432
57 I C 0.0000
58 I C -0.1344
59 P C -0.1114
60 L C 0.4218
61 F C 0.0000
62 E C -0.8107
63 L C -0.3434
64 D C 0.0000
65 S C -0.2566
66 Y C 0.2271
67 A C -0.0920
68 P C -0.4309
69 P C 0.0000
70 L C 0.0000
71 V C 0.0000
72 M C 0.0000
73 M C 0.0000
74 A C -0.2524
75 A C -0.2125
76 V C 0.2165
77 Y C 0.6456 mutated: EC77Y
78 G C -0.1619
79 D C -0.0660
80 T C -0.2660
81 L C -0.6900
82 D C -2.0499
83 P C -2.1221
84 E C -3.0080
85 V C 0.0000
86 E C -2.3349
87 R C -3.4049
88 R C -2.4836
89 Y C 0.0000
90 R C -2.3325
91 N C -2.3609
92 A C 0.0000
93 L C 0.0000
94 S C -0.8986
97 A C -0.0999
98 P C -0.6828
99 C C -0.8388
100 P C -1.0092
101 D C -1.7402
102 I C 0.0000
103 I C 0.2032
104 R C -0.2837
105 I C -0.4964
106 N C -1.3818
107 R C -1.0662
108 F C 0.0000
109 A C -1.1115
110 F C 0.0000
111 Y C 0.0000
112 E C -1.9107
113 R C -2.1629
114 A C 0.0000
115 Q C -2.6731
116 K C -2.8191
117 A C 0.0000
118 F C -0.8652
119 A C 0.0000
120 I C 0.0000
121 V C 0.0000
122 I C 0.0000
123 T C 0.0000
124 G C 0.0000
125 E C 0.0000
126 R C -1.8822
127 A C -1.5233
128 K C -1.2019
129 Y C -0.6213
130 G C 0.0000
131 N C 0.0000
132 I C 0.0000
133 L C 0.0000
134 L C 0.0000
135 K C -0.5140
136 K C 0.0000
137 G C 0.0000
138 V C -0.4292
139 T C -0.5775
140 P C -0.7530
1 M D 1.3770
2 L D 1.1057
3 K D -0.7081
4 T D -0.2075
5 I D 0.6558
6 S D 0.2063
7 P D 0.4179
8 L D 0.2806
9 I D 0.0000
10 S D -0.7290
11 P D -1.1279
12 E D -2.4169
13 L D 0.0000
14 L D -1.2027
15 K D -2.4215
16 V D 0.0000
17 L D 0.0000
18 A D -0.8353
19 E D -1.1456
20 M D 0.0000
21 G D 0.0000
22 H D 0.0000
23 G D -0.1705
24 D D 0.0000
25 E D -0.6232
26 I D 0.0000
27 I D 0.0000
28 F D 0.0000
29 S D 0.0000
30 D D 0.0000
31 A D -1.0573
32 H D 0.0000
33 F D 0.0000
34 P D 0.0000
35 A D 0.0000
36 H D -0.5933
37 S D -0.7886
38 M D -1.0448
39 G D -1.3194
40 P D -1.2512
41 Q D -0.8997
42 V D -0.4700
43 I D -0.7421
44 R D -1.2965
45 A D -0.9499
46 D D -1.9606
47 G D -1.2856
48 L D -0.5116
49 L D -0.1631
50 V D 0.0000
51 S D 0.0000
52 D D -1.2373
53 L D 0.0000
54 L D 0.0000
55 Q D -1.5511
56 A D -0.4519
57 I D 0.0000
58 I D -0.1275
59 P D -0.1441
60 L D 0.4640
61 F D 0.0000
62 E D -0.5226
63 L D -0.0778
64 D D 0.0000
65 S D -0.0521
66 Y D 0.2603
67 A D -0.0171
68 P D -0.3018
69 P D 0.0000
70 L D 0.0000
71 V D 0.0000
72 M D 0.0000
73 M D 0.0000
74 A D -0.2356
75 A D -0.3623
76 V D 0.3746
77 Y D 1.0449 mutated: ED77Y
78 G D 0.0047
79 D D -0.5459
80 T D -0.5824
81 L D -1.1548
82 D D -2.5724
83 P D -2.4209
84 E D -3.2418
85 V D 0.0000
86 E D -2.4669
87 R D -3.5994
88 R D -2.8188
89 Y D 0.0000
90 R D -2.3433
91 N D -2.2329
92 A D 0.0000
93 L D 0.0000
94 S D -0.8990
95 L D -0.3402
96 Q D -0.9195
97 A D -0.5397
98 P D -0.8349
99 C D -0.8429
100 P D -1.0356
101 D D -1.8033
102 I D 0.0000
103 I D -0.0076
104 R D -0.4039
105 I D -0.4337
106 N D -1.1740
107 R D -0.6235
108 F D -0.1362
109 A D -0.4752
110 F D 0.0000
111 Y D -0.6546
112 E D -1.1737
113 R D -1.3261
114 A D 0.0000
115 Q D -2.1373
116 K D -2.4701
117 A D 0.0000
118 F D 0.0000
119 A D 0.0000
120 I D 0.0000
121 V D 0.0000
122 I D 0.0000
123 T D 0.0000
124 G D 0.0000
125 E D 0.0000
126 R D -1.9738
127 A D -1.6556
128 K D -1.5824
129 Y D 0.0000
130 G D 0.0000
131 N D 0.0000
132 I D 0.0000
133 L D 0.0000
134 L D 0.0000
135 K D -0.3280
136 K D 0.0000
137 G D 0.0000
138 V D -0.2587
139 T D -0.4134
140 P D -0.5818
1 M E 1.4346
2 L E 1.1616
3 K E -0.6994
4 T E -0.2496
5 I E 0.6095
6 S E 0.2000
7 P E 0.5644
8 L E 0.5648
9 I E 0.0000
10 S E -0.6880
11 P E -1.1027
12 E E -2.4376
13 L E 0.0000
14 L E -1.2261
15 K E -2.4387
16 V E 0.0000
17 L E 0.0000
18 A E -0.8383
19 E E -1.1673
20 M E 0.0000
21 G E 0.0000
22 H E 0.0000
23 G E -0.0987
24 D E 0.0000
25 E E -0.5441
26 I E 0.0000
27 I E 0.0000
28 F E 0.0000
29 S E 0.0000
30 D E 0.0000
31 A E -1.0665
32 H E -0.6142
33 F E 0.0000
34 P E 0.0000
35 A E 0.0000
36 H E -0.5744
37 S E -0.7745
38 M E 0.0000
39 G E -1.1665
40 P E -1.1244
41 Q E -0.9920
42 V E -0.3528
43 I E -0.8176
44 R E -1.2718
45 A E -1.1227
46 D E -2.0897
47 G E -1.2071
48 L E -0.6027
49 L E -0.2228
50 V E 0.0000
51 S E -0.9597
52 D E -0.6536
53 L E 0.0000
54 L E 0.0000
55 Q E -1.1387
56 A E 0.0000
57 I E 0.0000
58 I E 0.0000
59 P E 0.1355
60 L E 0.4480
61 F E 0.0000
62 E E -0.6793
63 L E -0.1944
64 D E 0.0000
65 S E -0.2310
66 Y E 0.0157
67 A E -0.1176
68 P E 0.0000
69 P E 0.0000
70 L E 0.0000
71 V E 0.0000
72 M E 0.0000
73 M E 0.0000
74 A E 0.1014
75 A E 0.1971
76 V E 0.9036
77 Y E 1.1696 mutated: EE77Y
78 G E 0.1454
79 D E -0.0046
80 T E -0.1631
81 L E -0.4584
82 D E -1.6947
83 P E -2.0378
84 E E -3.1227
85 V E 0.0000
86 E E -2.5209
87 R E -3.6003
88 R E -2.8066
89 Y E 0.0000
90 R E -2.4340
91 N E -2.1995
92 A E 0.0000
93 L E 0.0000
94 S E -0.2330
95 L E 1.0266
97 A E 0.4316
98 P E -0.3707
99 C E 0.0000
100 P E -0.9963
101 D E -1.9839
102 I E 0.0000
103 I E 0.0000
104 R E -0.7188
105 I E 0.0000
106 N E -0.1743
107 R E -0.1627
108 F E 0.1436
109 A E 0.0000
110 F E 0.0000
111 Y E 0.0000
112 E E 0.0000
113 R E -0.9078
114 A E 0.0000
115 Q E -1.3746
116 K E -2.0609
117 A E 0.0000
118 F E -0.7058
119 A E 0.0000
120 I E 0.0000
121 V E 0.0000
122 I E 0.0000
123 T E 0.0000
124 G E -1.2506
125 E E 0.0000
126 R E -1.8832
127 A E -1.3802
128 K E -1.0266
129 Y E 0.0000
130 G E 0.0000
131 N E 0.0000
132 I E 0.0000
133 L E 0.0000
134 L E 0.0000
135 K E -0.3720
136 K E 0.0000
137 G E 0.0000
138 V E -0.2029
139 T E -0.3805
140 P E -0.6337
1 M F 1.4339
2 L F 1.2034
3 K F -0.7059
4 T F -0.3081
5 I F 0.4546
6 S F 0.2550
7 P F 0.4706
8 L F 0.4193
9 I F 0.0000
10 S F -0.7346
11 P F -1.0901
12 E F -2.5023
13 L F 0.0000
14 L F -1.1967
15 K F -2.4051
16 V F 0.0000
17 L F 0.0000
18 A F -0.8332
19 E F -1.1726
20 M F 0.0000
21 G F 0.0000
22 H F 0.0000
23 G F -0.0777
24 D F 0.0000
25 E F 0.0000
26 I F 0.0000
27 I F 0.0000
28 F F 0.0000
29 S F 0.0000
30 D F 0.0000
31 A F -1.0864
32 H F 0.0000
33 F F 0.0000
34 P F 0.0000
35 A F 0.0000
36 H F -0.6691
37 S F -0.9321
38 M F 0.0000
39 G F -1.4557
40 P F -1.3495
41 Q F -0.9408
42 V F -0.3251
43 I F -0.8000
44 R F -1.4409
45 A F -1.0333
46 D F -2.0326
47 G F -1.3339
48 L F -0.5350
49 L F -0.2733
50 V F 0.0000
51 S F -1.1223
52 D F -0.9189
53 L F 0.0000
54 L F 0.0000
55 Q F -1.5718
56 A F 0.0000
57 I F 0.0000
58 I F -0.1086
59 P F -0.0923
60 L F 0.5025
61 F F 0.0000
62 E F -0.6537
63 L F -0.1567
64 D F 0.0000
65 S F -0.0051
66 Y F 0.3919
67 A F 0.0562
68 P F -0.2026
69 P F 0.0000
70 L F 0.0000
71 V F 0.0000
72 M F 0.0000
73 M F 0.0000
74 A F -0.1296
75 A F -0.4249
76 V F 0.0000
77 Y F 0.7421 mutated: EF77Y
78 G F -0.2848
79 D F -0.7500
80 T F -0.6411
81 L F -1.1461
82 D F -2.7017
83 P F -2.4519
84 E F -3.2894
85 V F 0.0000
86 E F -2.4467
87 R F -3.5434
88 R F -2.6089
89 Y F 0.0000
90 R F -2.7163
91 N F -2.5947
92 A F 0.0000
93 L F 0.0000
94 S F -1.3631
95 L F 0.0000
96 Q F -1.6845
97 A F -0.7068
98 P F -0.4685
99 C F -0.2932
100 P F -0.6359
101 D F -1.4855
102 I F -0.3769
103 I F 0.3307
104 R F -0.1055
105 I F -0.1941
106 N F -0.8249
107 R F 0.0000
108 F F -0.2785
109 A F -0.9373
110 F F 0.0000
111 Y F -1.3062
112 E F -2.6457
113 R F -2.1109
114 A F 0.0000
115 Q F -2.9181
116 K F -2.9088
117 A F 0.0000
118 F F 0.0000
119 A F 0.0000
120 I F 0.0000
121 V F 0.0000
122 I F 0.0000
123 T F 0.0000
124 G F 0.0000
125 E F 0.0000
126 R F -2.0252
127 A F -1.7845
128 K F -1.7360
129 Y F 0.0000
130 G F 0.0000
131 N F 0.0000
132 I F 0.0000
133 L F 0.0000
134 L F 0.0000
135 K F -0.3273
136 K F 0.0000
137 G F 0.0000
138 V F -0.2968
139 T F -0.4231
140 P F -0.6296
1 M G 1.4718
2 L G 1.2374
3 K G -0.6818
4 T G -0.2486
5 I G 0.5931
6 S G 0.2389
7 P G 0.5827
8 L G 0.5308
9 I G 0.0000
10 S G -0.5726
11 P G -0.8586
12 E G -1.9541
13 L G 0.0000
14 L G -0.9796
15 K G -2.2269
16 V G 0.0000
17 L G 0.0000
18 A G -0.6202
19 E G -1.0898
20 M G 0.0000
21 G G 0.0000
22 H G -0.2148
23 G G -0.2399
24 D G 0.0000
25 E G -0.6543
26 I G 0.0000
27 I G 0.0000
28 F G 0.0000
29 S G 0.0000
30 D G 0.0000
31 A G -1.1289
32 H G -0.6343
33 F G 0.0000
34 P G 0.0000
35 A G 0.0000
36 H G -0.6703
37 S G -0.8729
38 M G -1.2890
39 G G -1.3624
40 P G -1.3071
41 Q G -0.8916
42 V G -0.5210
43 I G 0.0000
44 R G -1.3273
45 A G -1.0594
46 D G -2.0511
47 G G -1.3526
48 L G -0.5110
49 L G -0.3240
50 V G 0.0000
51 S G -1.1244
52 D G -0.6775
53 L G 0.0000
54 L G 0.0000
55 Q G -1.6078
56 A G 0.0000
57 I G 0.0000
58 I G 0.0000
59 P G -0.3371
60 L G 0.3488
61 F G 0.0000
62 E G -0.6133
63 L G -0.1265
64 D G 0.0000
65 S G -0.0864
66 Y G 0.3115
67 A G 0.0473
68 P G -0.3708
69 P G 0.0000
70 L G 0.0000
71 V G 0.0000
72 M G 0.0000
73 M G 0.0000
74 A G 0.2061
75 A G -0.0401
76 V G 0.5965
77 Y G 1.0831 mutated: EG77Y
78 G G 0.0467
79 D G -0.2855
80 T G -0.2776
81 L G -0.5987
82 D G -1.9518
83 P G -2.1055
84 E G -3.1500
85 V G 0.0000
86 E G -2.5062
87 R G -3.6603
88 R G -2.7952
89 Y G 0.0000
90 R G -2.9223
91 N G -2.5588
92 A G 0.0000
93 L G 0.0000
94 S G -1.0524
95 L G -0.3976
96 Q G -1.0832
97 A G -0.5501
98 P G -0.8240
99 C G -0.8953
100 P G -1.0720
101 D G -1.9102
102 I G 0.0000
103 I G -0.0607
104 R G -0.4450
105 I G 0.1841
106 N G 0.0199
107 R G 0.3304
108 F G 1.3707
109 A G 0.0530
110 F G 0.0000
111 Y G -0.5255
112 E G -1.6374
113 R G -1.7355
114 A G 0.0000
115 Q G -2.6913
116 K G -2.7390
117 A G 0.0000
118 F G 0.0000
119 A G 0.0000
120 I G 0.0000
121 V G 0.0000
122 I G 0.0000
123 T G 0.0000
124 G G 0.0000
125 E G 0.0000
126 R G -2.0111
127 A G -1.6397
128 K G -1.3850
129 Y G 0.0000
130 G G 0.0000
131 N G 0.0000
132 I G 0.0000
133 L G 0.0000
134 L G 0.0000
135 K G -0.3950
136 K G 0.0000
137 G G 0.0000
138 V G -0.2980
139 T G -0.4298
140 P G -0.6081
1 M H 1.3804
2 L H 0.9596
3 K H -0.7956
4 T H -0.3032
5 I H 0.5921
6 S H 0.2936
7 P H 0.7071
8 L H 0.9835
9 I H 0.0000
10 S H -0.6235
11 P H -1.1019
12 E H -2.4278
13 L H 0.0000
14 L H -1.1828
15 K H -2.4078
16 V H 0.0000
17 L H 0.0000
18 A H -0.8038
19 E H -1.0860
20 M H 0.0000
21 G H 0.0000
22 H H 0.0000
23 G H -0.1365
24 D H 0.0000
25 E H 0.0000
26 I H 0.0000
27 I H 0.0000
28 F H 0.0000
29 S H 0.0000
30 D H 0.0000
31 A H -0.9927
32 H H -0.6189
33 F H 0.0000
34 P H 0.0000
35 A H 0.0000
36 H H -0.6634
37 S H -0.6303
38 M H 0.0000
39 G H -1.3116
40 P H -1.2907
41 Q H -1.1164
42 V H -0.3830
43 I H -0.7871
44 R H -1.2073
45 A H -0.8989
46 D H -1.7964
47 G H -1.0432
48 L H -0.3206
49 L H -0.2607
50 V H 0.0000
51 S H -1.0852
52 D H -0.7481
53 L H 0.0000
54 L H 0.0000
55 Q H -1.5052
56 A H 0.0000
57 I H 0.0000
58 I H 0.0000
59 P H -0.2527
60 L H 0.5313
61 F H 0.0000
62 E H -0.5884
63 L H -0.1940
64 D H 0.0000
65 S H -0.2934
66 Y H -0.0313
67 A H -0.1416
68 P H 0.0000
69 P H 0.0000
70 L H 0.0000
71 V H 0.0000
72 M H 0.0000
73 M H 0.0000
74 A H 0.0600
75 A H 0.0668
76 V H 0.7386
77 Y H 1.0344 mutated: EH77Y
78 G H -0.0398
79 D H -0.2648
80 T H -0.2964
81 L H -0.6169
82 D H -1.9427
83 P H -2.0509
84 E H -2.9778
85 V H 0.0000
86 E H -2.5417
87 R H -3.5173
88 R H -2.6181
89 Y H 0.0000
90 R H -2.5090
91 N H -2.3293
92 A H 0.0000
93 L H 0.0000
94 S H -0.9144
95 L H -0.4312
96 Q H -0.8990
97 A H -0.4820
98 P H -0.8365
99 C H 0.0000
100 P H -1.1668
101 D H -2.2651
102 I H 0.0000
103 I H 0.0000
104 R H -0.6506
105 I H 0.0000
106 N H -0.0493
107 R H -0.1968
108 F H 0.1406
109 A H 0.0000
110 F H 0.0000
111 Y H 0.0000
112 E H 0.0000
113 R H -0.9149
114 A H 0.0000
115 Q H -1.9028
116 K H -2.2176
117 A H 0.0000
118 F H -0.6897
119 A H 0.0000
120 I H 0.0000
121 V H 0.0000
122 I H 0.0000
123 T H 0.0000
124 G H 0.0000
125 E H 0.0000
126 R H -1.9352
127 A H -1.5388
128 K H -1.1977
129 Y H 0.0000
130 G H 0.0000
131 N H 0.0000
132 I H 0.0000
133 L H 0.0000
134 L H 0.0000
135 K H -0.3012
136 K H 0.0000
137 G H 0.0000
138 V H -0.3801
139 T H -0.4010
140 P H -0.6175
1 M I 1.3575
2 L I 1.0463
3 K I -0.7679
4 T I -0.2854
5 I I 0.5255
6 S I 0.2173
7 P I 0.4302
8 L I 0.4864
9 I I 0.0000
10 S I -0.6722
11 P I -1.0470
12 E I -2.3352
13 L I 0.0000
14 L I -1.0340
15 K I -2.3365
16 V I 0.0000
17 L I 0.0000
18 A I -0.8181
19 E I -1.1222
20 M I 0.0000
21 G I 0.0000
22 H I -0.2361
23 G I -0.1881
24 D I 0.0000
25 E I -0.6365
26 I I 0.0000
27 I I 0.0000
28 F I 0.0000
29 S I 0.0000
30 D I 0.0000
31 A I -1.1106
32 H I -0.6743
33 F I 0.0000
34 P I 0.0000
35 A I 0.0000
36 H I -0.5972
37 S I -0.8101
38 M I -1.3446
39 G I -1.3992
40 P I -1.2735
41 Q I -0.7945
42 V I -0.4539
43 I I -0.7661
44 R I -1.3738
45 A I -0.9902
46 D I -1.9893
47 G I -1.2885
48 L I -0.2610
49 L I -0.1081
50 V I 0.0000
51 S I 0.0000
52 D I -0.6918
53 L I 0.0000
54 L I 0.0000
55 Q I -1.0850
56 A I 0.0000
57 I I 0.0000
58 I I -0.0772
59 P I -0.1496
60 L I 0.4405
61 F I 0.0000
62 E I -0.6630
63 L I -0.2103
64 D I 0.0000
65 S I -0.2446
66 Y I -0.0421
67 A I -0.1793
68 P I -0.2764
69 P I -0.3550
70 L I 0.0000
71 V I 0.0000
72 M I 0.0000
73 M I 0.0000
74 A I -0.0277
75 A I -0.4500
76 V I 0.0000
77 Y I -0.0243 mutated: EI77Y
78 G I -0.2022
79 D I -0.3252
80 T I -0.5727
81 L I -1.3076
82 D I -2.7880
83 P I -2.5504
84 E I -3.1669
85 V I 0.0000
86 E I -2.7133
87 R I -3.7155
88 R I -2.6677
89 Y I 0.0000
90 R I -2.4567
91 N I -2.4664
92 A I 0.0000
93 L I 0.0000
94 S I -0.9277
95 L I -0.3467
96 Q I -1.0657
97 A I -0.6093
98 P I -0.8362
99 C I 0.0000
100 P I -0.6933
101 D I -0.9093
102 I I 0.0000
103 I I 0.1005
104 R I -0.2033
105 I I 0.0611
106 N I -0.4163
107 R I 0.0000
108 F I 0.3629
109 A I -0.5023
110 F I 0.0000
111 Y I -1.1299
112 E I -2.5448
113 R I -2.1626
114 A I 0.0000
115 Q I -2.9028
116 K I -2.9409
117 A I 0.0000
118 F I 0.0000
119 A I 0.0000
120 I I 0.0000
121 V I 0.0000
122 I I 0.0000
123 T I 0.0000
124 G I 0.0000
125 E I 0.0000
126 R I -2.0683
127 A I -1.7384
128 K I -1.6240
129 Y I 0.0000
130 G I 0.0000
131 N I 0.0000
132 I I 0.0000
133 L I 0.0000
134 L I 0.0000
135 K I -0.4310
136 K I 0.0000
137 G I 0.0000
138 V I -0.4197
139 T I -0.4586
140 P I -0.5838
1 M J 1.3116
2 L J 0.8562
3 K J -0.8513
4 T J -0.3226
5 I J 0.5681
6 S J 0.1749
7 P J 0.5419
8 L J 0.7487
9 I J 0.0000
10 S J -0.6595
11 P J -1.1148
12 E J -2.4240
13 L J 0.0000
14 L J -1.1766
15 K J -2.4256
16 V J 0.0000
17 L J 0.0000
18 A J -0.8245
19 E J -1.1554
20 M J 0.0000
21 G J 0.0000
22 H J 0.0000
23 G J -0.0415
24 D J 0.0000
25 E J -0.5748
26 I J 0.0000
27 I J 0.0000
28 F J 0.0000
29 S J 0.0000
30 D J 0.0000
31 A J -1.0839
32 H J -0.6618
33 F J 0.0000
34 P J 0.0000
35 A J 0.0000
36 H J -0.5218
37 S J -0.7056
38 M J -0.9060
39 G J -1.2340
40 P J -1.1150
41 Q J -0.8331
42 V J -0.2802
43 I J -0.8181
44 R J -1.3958
45 A J -1.1293
46 D J -2.1183
47 G J -1.2297
48 L J -0.4604
49 L J -0.2862
50 V J 0.0000
51 S J 0.0000
52 D J -0.7084
53 L J 0.0000
54 L J 0.0000
55 Q J -1.2770
56 A J 0.0000
57 I J 0.0000
58 I J 0.0000
59 P J -0.0452
60 L J 0.7670
61 F J 0.0000
62 E J -0.5029
63 L J -0.2200
64 D J 0.0000
65 S J -0.1293
66 Y J 0.5057
67 A J 0.1591
68 P J -0.4731
69 P J -0.5149
70 L J 0.0000
71 V J 0.0000
72 M J 0.0000
73 M J 0.0000
74 A J 0.2416
75 A J 0.1134
76 V J 0.9091
77 Y J 0.7072 mutated: EJ77Y
78 G J 0.0000
79 D J -0.1040
80 T J -0.0711
81 L J -0.4274
82 D J -1.9249
83 P J -1.9940
84 E J -3.0826
85 V J 0.0000
86 E J 0.0000
87 R J -3.4381
88 R J -2.5688
89 Y J 0.0000
90 R J -2.4159
91 N J -2.0122
92 A J 0.0000
93 L J 0.0000
94 S J -0.5657
95 L J 0.2838
96 Q J -0.6818
97 A J -0.3872
98 P J -0.2690
99 C J -0.6332
100 P J -1.0258
101 D J -1.8454
102 I J 0.0000
103 I J 0.0000
104 R J -0.3689
105 I J 0.0000
106 N J 0.1677
107 R J 0.5089
108 F J 1.3628
109 A J 0.0000
110 F J 0.0000
111 Y J 0.0151
112 E J -0.4567
113 R J 0.0000
114 A J 0.0000
115 Q J -1.9222
116 K J -2.2338
117 A J 0.0000
118 F J -0.7114
119 A J 0.0000
120 I J 0.0000
121 V J 0.0000
122 I J 0.0000
123 T J 0.0000
124 G J 0.0000
125 E J 0.0000
126 R J -1.9678
127 A J -1.6449
128 K J -1.4378
129 Y J -0.7284
130 G J 0.0000
131 N J 0.0000
132 I J 0.0000
133 L J 0.0000
134 L J 0.0000
135 K J -0.4674
136 K J -0.4661
137 G J 0.0000
138 V J -0.3455
139 T J -0.3739
140 P J -0.7013

 

Laboratory of Theory of Biopolymers 2015