Project name: 2WCV [mutate: EA112L, EB112L, EC112L, ED112L, EE112L, EF112L, EG112L, EH112L, EI112L, EJ112L]

Status: done

submitted: 2017-09-13 11:09:50, status changed: 2017-09-13 11:59:40
Settings
Chain sequence(s) A: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
C: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
B: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
E: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
D: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
G: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
F: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
I: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
H: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
J: MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
Distance of aggregation 10 Å
Dynamic mode No
Mutated residues EA112L, EB112L, EC112L, ED112L, EE112L, EF112L, EG112L, EH112L, EI112L, EJ112L
Energy difference between WT (input) and mutated protein (by FoldX) -6.05692 kcal/mol
Show buried residues

Minimal score value
-3.6894
Maximal score value
1.6992
Average score
-0.524
Total score value
-731.0029

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
1 M A 1.4699
2 L A 1.2603
3 K A -0.6434
4 T A -0.2068
5 I A 0.6701
6 S A 0.3480
7 P A 0.5483
8 L A 0.5338
9 I A 0.0000
10 S A -0.7339
11 P A -1.1126
12 E A -2.4394
13 L A 0.0000
14 L A -1.1468
15 K A -2.4379
16 V A 0.0000
17 L A 0.0000
18 A A -0.8463
19 E A -1.1283
20 M A 0.0000
21 G A 0.0000
22 H A 0.0000
23 G A -0.1131
24 D A 0.0000
25 E A -0.5849
26 I A 0.0000
27 I A 0.0000
28 F A 0.0000
29 S A 0.0000
30 D A 0.0000
31 A A -1.1177
32 H A -0.5871
33 F A 0.0000
34 P A 0.0000
35 A A 0.0000
36 H A -0.5806
37 S A -0.6334
38 M A -0.7186
39 G A -1.2687
40 P A -1.2134
41 Q A -0.9209
42 V A -0.3518
43 I A -0.8162
44 R A -1.2640
45 A A -1.0882
46 D A -2.1028
47 G A -1.4398
48 L A -0.6711
49 L A -0.4332
50 V A 0.0000
51 S A 0.0000
52 D A -0.7999
53 L A 0.0000
54 L A 0.0000
55 Q A -1.5532
56 A A 0.0000
57 I A 0.0000
58 I A -0.0982
59 P A -0.0745
60 L A 0.5163
61 F A 0.0000
62 E A -0.6157
63 L A -0.1660
64 D A 0.0000
65 S A -0.2721
66 Y A 0.1362
67 A A 0.1258
68 P A -0.0665
69 P A 0.0000
70 L A 0.0000
71 V A 0.0000
72 M A 0.0000
73 M A 0.0000
74 A A -0.0093
75 A A -0.6349
76 V A 0.0000
77 E A -1.4305
78 G A -0.9365
79 D A -0.6986
80 T A -0.7684
81 L A -1.0077
82 D A -2.4804
83 P A -2.3162
84 E A -3.2265
85 V A 0.0000
86 E A -2.4906
87 R A -3.3642
88 R A -2.5913
89 Y A 0.0000
90 R A -2.6777
91 N A -2.4181
92 A A -1.7940
93 L A 0.0000
94 S A -0.9158
95 L A -0.5748
98 P A -0.0542
99 C A 0.0896
100 P A -0.3780
101 D A -1.4535
102 I A 0.0000
103 I A 0.5040
104 R A 0.0107
105 I A 0.3709
106 N A 0.1065
107 R A 0.0000
108 F A 1.5302
109 A A 0.9999
110 F A 0.0000
111 Y A 0.7957
112 L A 1.1110 mutated: EA112L
113 R A -0.2358
114 A A 0.0000
115 Q A -1.3752
116 K A -2.0003
117 A A 0.0000
118 F A -0.7557
119 A A 0.0000
120 I A 0.0000
121 V A 0.0000
122 I A 0.0000
123 T A 0.0000
124 G A -1.3940
125 E A 0.0000
126 R A -2.0233
127 A A -1.6667
128 K A -1.4036
129 Y A 0.0000
130 G A 0.0000
131 N A 0.0000
132 I A 0.0000
133 L A 0.0000
134 L A 0.0000
135 K A -0.4033
136 K A 0.0000
137 G A 0.0000
138 V A -0.3362
139 T A -0.3938
140 P A -0.6023
1 M B 1.1962
2 L B 0.7121
3 K B -0.9363
4 T B -0.3911
5 I B 0.3749
6 S B 0.1490
7 P B 0.4139
8 L B 0.4679
9 I B 0.0000
10 S B -0.7025
11 P B -1.1022
12 E B -2.3082
13 L B 0.0000
14 L B -1.1334
15 K B -2.3595
16 V B 0.0000
17 L B 0.0000
18 A B -0.6343
19 E B -1.1229
20 M B 0.0000
21 G B 0.0000
22 H B -0.2478
23 G B -0.4658
24 D B 0.0000
25 E B -0.6337
26 I B 0.0000
27 I B 0.0000
28 F B 0.0000
29 S B 0.0000
30 D B 0.0000
31 A B -1.1369
32 H B 0.0000
33 F B 0.0000
34 P B 0.0000
35 A B 0.0000
36 H B -0.6544
37 S B -0.7874
38 M B -0.9255
39 G B -1.3126
40 P B -1.2761
41 Q B -1.0129
42 V B -0.4002
43 I B -0.8385
44 R B -1.2937
45 A B -1.0696
46 D B -2.0651
47 G B -1.3639
48 L B -0.3429
49 L B -0.2622
50 V B 0.0000
51 S B -1.1783
52 D B -0.7518
53 L B 0.0000
54 L B 0.0000
55 Q B -1.6631
56 A B 0.0000
57 I B 0.0000
58 I B 0.0000
59 P B -0.3401
60 L B 0.2890
61 F B 0.0000
62 E B -0.7648
63 L B -0.2366
64 D B 0.0000
65 S B -0.0852
66 Y B 0.2814
67 A B 0.1583
68 P B -0.3489
69 P B 0.0000
70 L B 0.0000
71 V B 0.0000
72 M B 0.0000
73 M B 0.0000
74 A B 0.0000
75 A B -0.6466
76 V B -0.3706
77 E B -1.4511
78 G B -1.3595
79 D B -1.4874
80 T B -1.3775
81 L B -1.1313
82 D B -2.4449
83 P B -2.0307
84 E B -2.7283
85 V B 0.0000
86 E B -2.5307
87 R B -3.6572
88 R B -2.7930
89 Y B 0.0000
90 R B -3.1742
91 N B -2.7115
92 A B 0.0000
93 L B 0.0000
94 S B -1.1181
95 L B -0.5062
96 Q B -1.1063
97 A B -0.5519
98 P B -0.9230
99 C B -0.9919
100 P B -1.1338
101 D B -1.9930
102 I B 0.0000
103 I B -0.6711
104 R B -0.5036
105 I B 0.0000
106 N B 0.0016
107 R B 0.5077
108 F B 1.6992
109 A B 0.0000
110 F B 0.0000
111 Y B 0.2042
112 L B 0.0000 mutated: EB112L
113 R B -0.6437
114 A B 0.0000
115 Q B -1.8393
116 K B -2.4660
117 A B 0.0000
118 F B 0.0000
119 A B 0.0000
120 I B 0.0000
121 V B 0.0000
122 I B 0.0000
123 T B 0.0000
124 G B -1.2823
125 E B 0.0000
126 R B -2.0708
127 A B -1.5257
128 K B -1.5868
129 Y B 0.0000
130 G B 0.0000
131 N B 0.0000
132 I B 0.0000
133 L B 0.0000
134 L B 0.0000
135 K B -0.4467
136 K B 0.0000
137 G B 0.0000
138 V B -0.3027
139 T B -0.4352
140 P B -0.5413
1 M C 1.4930
2 L C 1.2700
3 K C -0.6383
4 T C -0.2041
5 I C 0.6572
6 S C 0.4281
7 P C 0.6455
8 L C 0.6550
9 I C 0.0000
10 S C -0.6862
11 P C -1.0904
12 E C -2.3816
13 L C 0.0000
14 L C -1.1561
15 K C -2.4117
16 V C 0.0000
17 L C 0.0000
18 A C -0.8139
19 E C -1.0594
20 M C 0.0000
21 G C 0.0000
22 H C 0.0000
23 G C -0.1574
24 D C 0.0000
25 E C -0.7002
26 I C 0.0000
27 I C 0.0000
28 F C 0.0000
29 S C 0.0000
30 D C 0.0000
31 A C -1.0835
32 H C -0.6072
33 F C 0.0000
34 P C 0.0000
35 A C 0.0000
36 H C -0.5749
37 S C -0.8995
38 M C 0.0000
39 G C -1.4379
40 P C -1.2601
41 Q C -0.7911
42 V C -0.2579
43 I C -0.7384
44 R C -1.2116
45 A C -1.0378
46 D C -2.0576
47 G C -1.2120
48 L C -0.6650
49 L C -0.4725
50 V C 0.0000
51 S C -0.9143
52 D C -0.8877
53 L C 0.0000
54 L C 0.0000
55 Q C -1.4637
56 A C -0.3937
57 I C 0.0000
58 I C -0.1507
59 P C -0.1193
60 L C 0.4381
61 F C 0.0000
62 E C -0.8019
63 L C -0.3146
64 D C 0.0000
65 S C -0.1594
66 Y C 0.0601
67 A C 0.0054
68 P C -0.3898
69 P C 0.0000
70 L C 0.0000
71 V C 0.0000
72 M C 0.0000
73 M C 0.0000
74 A C -0.6560
75 A C -0.9947
76 V C -1.3054
77 E C -2.4828
78 G C -1.6929
79 D C -1.1041
80 T C -0.7997
81 L C -0.6881
82 D C -2.0489
83 P C -2.1219
84 E C -3.0075
85 V C 0.0000
86 E C -2.3343
87 R C -3.4040
88 R C -2.4817
89 Y C 0.0000
90 R C -2.3417
91 N C -2.3734
92 A C 0.0000
93 L C 0.0000
94 S C -0.9140
97 A C -0.0999
98 P C -0.6828
99 C C -0.8388
100 P C -1.0092
101 D C -1.7402
102 I C 0.0000
103 I C 0.2032
104 R C -0.2836
105 I C -0.4817
106 N C -1.5858
107 R C -1.2392
108 F C 0.0000
109 A C -0.6511
110 F C 0.0000
111 Y C -1.0292
112 L C -1.0427 mutated: EC112L
113 R C -1.5558
114 A C 0.0000
115 Q C -2.2472
116 K C -2.5452
117 A C 0.0000
118 F C -0.8645
119 A C 0.0000
120 I C 0.0000
121 V C 0.0000
122 I C 0.0000
123 T C 0.0000
124 G C 0.0000
125 E C 0.0000
126 R C -1.9036
127 A C -1.5364
128 K C -1.2167
129 Y C -0.6314
130 G C 0.0000
131 N C 0.0000
132 I C 0.0000
133 L C 0.0000
134 L C 0.0000
135 K C -0.4912
136 K C 0.0000
137 G C 0.0000
138 V C -0.4045
139 T C -0.5724
140 P C -0.7530
1 M D 1.3532
2 L D 1.0625
3 K D -0.7431
4 T D -0.2503
5 I D 0.5801
6 S D 0.1682
7 P D 0.3942
8 L D 0.2700
9 I D 0.0000
10 S D -0.7260
11 P D -1.1266
12 E D -2.4135
13 L D 0.0000
14 L D -1.1967
15 K D -2.4139
16 V D 0.0000
17 L D 0.0000
18 A D -0.8239
19 E D -1.1397
20 M D 0.0000
21 G D 0.0000
22 H D 0.0000
23 G D -0.3646
24 D D 0.0000
25 E D -0.6237
26 I D 0.0000
27 I D 0.0000
28 F D 0.0000
29 S D 0.0000
30 D D 0.0000
31 A D -1.0573
32 H D 0.0000
33 F D 0.0000
34 P D 0.0000
35 A D 0.0000
36 H D -0.5938
37 S D -0.7920
38 M D -0.9391
39 G D -1.3251
40 P D -1.2603
41 Q D -0.8999
42 V D -0.4702
43 I D -0.7421
44 R D -1.2965
45 A D -0.9499
46 D D -1.9606
47 G D -1.2856
48 L D -0.5116
49 L D -0.1631
50 V D 0.0000
51 S D 0.0000
52 D D -1.2365
53 L D 0.0000
54 L D 0.0000
55 Q D -1.5436
56 A D -0.4563
57 I D 0.0000
58 I D -0.1057
59 P D -0.1172
60 L D 0.4990
61 F D 0.0000
62 E D -0.4949
63 L D -0.0769
64 D D 0.0000
65 S D -0.0836
66 Y D 0.2032
67 A D -0.0341
68 P D -0.3184
69 P D 0.0000
70 L D 0.0000
71 V D 0.0000
72 M D 0.0000
73 M D 0.0000
74 A D -0.6029
75 A D -1.0718
76 V D -1.0852
77 E D -2.0443
78 G D -1.5005
79 D D -1.4539
80 T D -0.9960
81 L D -1.1392
82 D D -2.5495
83 P D -2.4082
84 E D -3.2314
85 V D 0.0000
86 E D -2.4577
87 R D -3.5912
88 R D -2.8097
89 Y D 0.0000
90 R D -2.3399
91 N D -2.2294
92 A D 0.0000
93 L D 0.0000
94 S D -0.8962
95 L D -0.3370
96 Q D -0.9161
97 A D -0.5379
98 P D -0.8349
99 C D -0.8433
100 P D -1.0363
101 D D -1.8035
102 I D 0.0000
103 I D -0.0105
104 R D -0.4100
105 I D -0.4441
106 N D -1.1076
107 R D -0.5319
108 F D 0.0397
109 A D -0.2105
110 F D 0.0000
111 Y D -0.3170
112 L D -0.4478 mutated: ED112L
113 R D -0.9631
114 A D 0.0000
115 Q D -1.9042
116 K D -2.3259
117 A D 0.0000
118 F D 0.0000
119 A D 0.0000
120 I D 0.0000
121 V D 0.0000
122 I D 0.0000
123 T D 0.0000
124 G D 0.0000
125 E D 0.0000
126 R D -1.9738
127 A D -1.6518
128 K D -1.5788
129 Y D 0.0000
130 G D 0.0000
131 N D 0.0000
132 I D 0.0000
133 L D 0.0000
134 L D 0.0000
135 K D -0.3331
136 K D 0.0000
137 G D 0.0000
138 V D -0.2715
139 T D -0.3994
140 P D -0.5762
1 M E 1.4138
2 L E 1.1184
3 K E -0.7195
4 T E -0.2579
5 I E 0.6014
6 S E 0.1985
7 P E 0.5558
8 L E 0.5708
9 I E 0.0000
10 S E -0.6869
11 P E -1.1079
12 E E -2.4376
13 L E 0.0000
14 L E -1.2205
15 K E -2.4287
16 V E 0.0000
17 L E 0.0000
18 A E -0.8204
19 E E -1.1300
20 M E 0.0000
21 G E 0.0000
22 H E 0.0000
23 G E -0.0555
24 D E 0.0000
25 E E 0.0000
26 I E 0.0000
27 I E 0.0000
28 F E 0.0000
29 S E 0.0000
30 D E 0.0000
31 A E -1.0482
32 H E -0.6262
33 F E 0.0000
34 P E 0.0000
35 A E 0.0000
36 H E -0.5924
37 S E -0.8175
38 M E 0.0000
39 G E -1.1757
40 P E -1.1273
41 Q E -0.9960
42 V E -0.3552
43 I E -0.8131
44 R E -1.2568
45 A E -1.0882
46 D E -2.0526
47 G E -1.1664
48 L E -0.5249
49 L E -0.0807
50 V E 0.0000
51 S E -0.9078
52 D E -0.5819
53 L E 0.0000
54 L E 0.0000
55 Q E -1.1293
56 A E 0.0000
57 I E 0.0000
58 I E 0.0000
59 P E 0.1361
60 L E 0.4487
61 F E 0.0000
62 E E -0.6794
63 L E -0.1946
64 D E 0.0000
65 S E -0.2292
66 Y E 0.0180
67 A E -0.1172
68 P E 0.0000
69 P E 0.0000
70 L E 0.0000
71 V E 0.0000
72 M E 0.0000
73 M E 0.0000
74 A E -0.2727
75 A E -0.6099
76 V E -0.6643
77 E E -1.9861
78 G E -1.4053
79 D E -1.0100
80 T E -0.6726
81 L E -0.5503
82 D E -1.7480
83 P E -2.0530
84 E E -3.1330
85 V E 0.0000
86 E E -2.5318
87 R E -3.6064
88 R E -2.8157
89 Y E 0.0000
90 R E -2.4043
91 N E -2.2025
92 A E 0.0000
93 L E 0.0000
94 S E -0.2330
95 L E 1.0272
97 A E 0.4316
98 P E -0.3454
99 C E 0.0000
100 P E -0.8982
101 D E -1.7853
102 I E 0.0000
103 I E 0.0000
104 R E -0.7032
105 I E 0.0000
106 N E -0.1091
107 R E 0.0000
108 F E -0.2800
109 A E 0.0000
110 F E 0.0000
111 Y E 0.0000
112 L E 0.0000 mutated: EE112L
113 R E -1.0429
114 A E 0.0000
115 Q E -1.5775
116 K E -2.0261
117 A E 0.0000
118 F E -0.6434
119 A E 0.0000
120 I E 0.0000
121 V E 0.0000
122 I E 0.0000
123 T E 0.0000
124 G E 0.0000
125 E E 0.0000
126 R E -1.8814
127 A E -1.4313
128 K E -1.1630
129 Y E 0.0000
130 G E 0.0000
131 N E 0.0000
132 I E 0.0000
133 L E 0.0000
134 L E 0.0000
135 K E -0.3015
136 K E 0.0000
137 G E 0.0000
138 V E -0.2028
139 T E -0.3805
140 P E -0.6337
1 M F 1.4334
2 L F 1.2025
3 K F -0.7069
4 T F -0.3096
5 I F 0.4512
6 S F 0.2532
7 P F 0.4698
8 L F 0.4189
9 I F 0.0000
10 S F -0.7354
11 P F -1.0912
12 E F -2.5033
13 L F 0.0000
14 L F -1.2001
15 K F -2.4066
16 V F 0.0000
17 L F 0.0000
18 A F -0.8340
19 E F -1.1726
20 M F 0.0000
21 G F 0.0000
22 H F 0.0000
23 G F -0.0796
24 D F 0.0000
25 E F 0.0000
26 I F 0.0000
27 I F 0.0000
28 F F 0.0000
29 S F 0.0000
30 D F 0.0000
31 A F -1.0864
32 H F 0.0000
33 F F 0.0000
34 P F 0.0000
35 A F 0.0000
36 H F -0.6691
37 S F -0.9273
38 M F 0.0000
39 G F -1.4557
40 P F -1.3495
41 Q F -0.9408
42 V F -0.3251
43 I F -0.8000
44 R F -1.4409
45 A F -1.0333
46 D F -2.0326
47 G F -1.3339
48 L F -0.5350
49 L F -0.2733
50 V F 0.0000
51 S F -1.1241
52 D F -0.9189
53 L F 0.0000
54 L F 0.0000
55 Q F -1.5739
56 A F 0.0000
57 I F 0.0000
58 I F -0.1006
59 P F -0.0876
60 L F 0.5101
61 F F 0.0000
62 E F -0.6190
63 L F -0.1313
64 D F 0.0000
65 S F -0.0079
66 Y F 0.3753
67 A F 0.0485
68 P F -0.2065
69 P F 0.0000
70 L F 0.0000
71 V F 0.0000
72 M F 0.0000
73 M F 0.0000
74 A F -0.5885
75 A F -1.2556
76 V F 0.0000
77 E F -2.7105
78 G F -1.8761
79 D F -1.6937
80 T F -1.1550
81 L F -1.1832
82 D F -2.6474
83 P F -2.4277
84 E F -3.2712
85 V F 0.0000
86 E F -2.4377
87 R F -3.5346
88 R F -2.6128
89 Y F 0.0000
90 R F -2.7348
91 N F -2.6030
92 A F 0.0000
93 L F 0.0000
94 S F -1.3690
95 L F 0.0000
96 Q F -1.6897
97 A F -0.7084
98 P F -0.4701
99 C F -0.2967
100 P F -0.6388
101 D F -1.4978
102 I F -0.3986
103 I F 0.2963
104 R F -0.1647
105 I F -0.2072
106 N F -1.1698
107 R F 0.0000
108 F F -0.0562
109 A F 0.0550
110 F F 0.0000
111 Y F -0.1958
112 L F 0.1476 mutated: EF112L
113 R F -0.7395
114 A F 0.0000
115 Q F -1.9162
116 K F -2.2602
117 A F 0.0000
118 F F 0.0000
119 A F 0.0000
120 I F 0.0000
121 V F 0.0000
122 I F 0.0000
123 T F 0.0000
124 G F 0.0000
125 E F 0.0000
126 R F -2.0252
127 A F -1.7782
128 K F -1.7344
129 Y F 0.0000
130 G F 0.0000
131 N F 0.0000
132 I F 0.0000
133 L F 0.0000
134 L F 0.0000
135 K F -0.3213
136 K F 0.0000
137 G F 0.0000
138 V F -0.2937
139 T F -0.4147
140 P F -0.6261
1 M G 1.3690
2 L G 1.0294
3 K G -0.7903
4 T G -0.3160
5 I G 0.4897
6 S G 0.1777
7 P G 0.5237
8 L G 0.5240
9 I G 0.0000
10 S G -0.5750
11 P G -0.8842
12 E G -1.9570
13 L G 0.0000
14 L G -0.9968
15 K G -2.2313
16 V G 0.0000
17 L G 0.0000
18 A G -0.6261
19 E G -1.0993
20 M G 0.0000
21 G G 0.0000
22 H G -0.2079
23 G G -0.2313
24 D G 0.0000
25 E G -0.6613
26 I G 0.0000
27 I G 0.0000
28 F G 0.0000
29 S G 0.0000
30 D G 0.0000
31 A G -1.1289
32 H G -0.6350
33 F G 0.0000
34 P G 0.0000
35 A G 0.0000
36 H G -0.6998
37 S G -0.9012
38 M G 0.0000
39 G G -1.3724
40 P G -1.3093
41 Q G -0.9056
42 V G -0.5335
43 I G 0.0000
44 R G -1.3273
45 A G -1.0594
46 D G -2.0511
47 G G -1.3526
48 L G -0.5110
49 L G -0.3240
50 V G 0.0000
51 S G -1.1244
52 D G -0.6775
53 L G 0.0000
54 L G 0.0000
55 Q G -1.6106
56 A G 0.0000
57 I G 0.0000
58 I G 0.0000
59 P G -0.3568
60 L G 0.3148
61 F G 0.0000
62 E G -0.6175
63 L G -0.1157
64 D G 0.0000
65 S G -0.0814
66 Y G 0.3136
67 A G 0.0503
68 P G -0.3674
69 P G 0.0000
70 L G 0.0000
71 V G 0.0000
72 M G 0.0000
73 M G 0.0000
74 A G -0.3426
75 A G -0.8516
76 V G -0.9792
77 E G -2.0438
78 G G -1.4828
79 D G -1.2069
80 T G -0.7572
81 L G -0.5946
82 D G -1.9501
83 P G -2.1055
84 E G -3.1500
85 V G 0.0000
86 E G -2.5062
87 R G -3.6603
88 R G -2.7952
89 Y G 0.0000
90 R G -2.9223
91 N G -2.5588
92 A G 0.0000
93 L G 0.0000
94 S G -1.0524
95 L G -0.3976
96 Q G -1.0832
97 A G -0.5501
98 P G -0.8240
99 C G -0.8931
100 P G -1.0699
101 D G -1.9106
102 I G 0.0000
103 I G -0.0640
104 R G -0.4962
105 I G -0.0634
106 N G -0.4703
107 R G -0.0980
108 F G 0.8110
109 A G 0.1788
110 F G 0.0000
111 Y G -0.0140
112 L G -0.0520 mutated: EG112L
113 R G -0.9633
114 A G 0.0000
115 Q G -1.9812
116 K G -2.4591
117 A G 0.0000
118 F G 0.0000
119 A G 0.0000
120 I G 0.0000
121 V G 0.0000
122 I G 0.0000
123 T G 0.0000
124 G G 0.0000
125 E G 0.0000
126 R G -2.0106
127 A G -1.6381
128 K G -1.3804
129 Y G 0.0000
130 G G 0.0000
131 N G 0.0000
132 I G 0.0000
133 L G 0.0000
134 L G 0.0000
135 K G -0.3932
136 K G 0.0000
137 G G 0.0000
138 V G -0.2817
139 T G -0.4266
140 P G -0.6057
1 M H 1.2764
2 L H 0.7349
3 K H -0.9103
4 T H -0.3692
5 I H 0.5067
6 S H 0.2533
7 P H 0.6697
8 L H 1.0174
9 I H 0.0000
10 S H -0.6156
11 P H -1.1238
12 E H -2.4300
13 L H 0.0000
14 L H -1.1901
15 K H -2.4105
16 V H 0.0000
17 L H 0.0000
18 A H -0.8062
19 E H -1.0893
20 M H 0.0000
21 G H 0.0000
22 H H 0.0000
23 G H -0.1126
24 D H 0.0000
25 E H 0.0000
26 I H 0.0000
27 I H 0.0000
28 F H 0.0000
29 S H 0.0000
30 D H 0.0000
31 A H -0.9885
32 H H -0.6118
33 F H 0.0000
34 P H 0.0000
35 A H 0.0000
36 H H -0.6507
37 S H -0.7636
38 M H 0.0000
39 G H -1.1914
40 P H -1.1889
41 Q H -1.0731
42 V H -0.3914
43 I H -0.7909
44 R H -1.2093
45 A H -0.8947
46 D H -1.7972
47 G H -1.0409
48 L H -0.3192
49 L H -0.2662
50 V H 0.0000
51 S H -1.0870
52 D H -0.7560
53 L H 0.0000
54 L H 0.0000
55 Q H -1.5063
56 A H 0.0000
57 I H 0.0000
58 I H 0.0000
59 P H -0.2557
60 L H 0.5275
61 F H 0.0000
62 E H -0.5875
63 L H -0.1888
64 D H 0.0000
65 S H -0.2659
66 Y H 0.0009
67 A H -0.1331
68 P H 0.0000
69 P H 0.0000
70 L H 0.0000
71 V H 0.0000
72 M H 0.0000
73 M H 0.0000
74 A H -0.3489
75 A H -0.7440
76 V H -0.7987
77 E H -2.1079
78 G H -1.5800
79 D H -1.2607
80 T H -0.7726
81 L H -0.5560
82 D H -1.9044
83 P H -2.0308
84 E H -2.9659
85 V H 0.0000
86 E H -2.5159
87 R H -3.5013
88 R H -2.6070
89 Y H 0.0000
90 R H -2.4773
91 N H -2.3136
92 A H 0.0000
93 L H 0.0000
94 S H -0.9068
95 L H -0.4276
96 Q H -0.8990
97 A H -0.4824
98 P H -0.8331
99 C H 0.0000
100 P H -1.1668
101 D H -2.2286
102 I H 0.0000
103 I H 0.0000
104 R H -0.6177
105 I H 0.0000
106 N H -0.3807
107 R H -0.3716
108 F H -0.2589
109 A H 0.0000
110 F H 0.0000
111 Y H 0.0000
112 L H 0.0000 mutated: EH112L
113 R H -0.9347
114 A H 0.0000
115 Q H -1.6784
116 K H -2.0132
117 A H 0.0000
118 F H -0.6331
119 A H 0.0000
120 I H 0.0000
121 V H 0.0000
122 I H 0.0000
123 T H 0.0000
124 G H 0.0000
125 E H 0.0000
126 R H -1.9287
127 A H -1.5215
128 K H -1.1640
129 Y H 0.0000
130 G H 0.0000
131 N H 0.0000
132 I H 0.0000
133 L H 0.0000
134 L H 0.0000
135 K H -0.2883
136 K H 0.0000
137 G H 0.0000
138 V H -0.3757
139 T H -0.4010
140 P H -0.6175
1 M I 1.3135
2 L I 0.9720
3 K I -0.8073
4 T I -0.3113
5 I I 0.4783
6 S I 0.1781
7 P I 0.3871
8 L I 0.4335
9 I I 0.0000
10 S I -0.6895
11 P I -1.0664
12 E I -2.3406
13 L I 0.0000
14 L I -1.0581
15 K I -2.3448
16 V I 0.0000
17 L I 0.0000
18 A I -0.8226
19 E I -1.1243
20 M I 0.0000
21 G I 0.0000
22 H I -0.2417
23 G I -0.1940
24 D I 0.0000
25 E I -0.6386
26 I I 0.0000
27 I I 0.0000
28 F I 0.0000
29 S I 0.0000
30 D I 0.0000
31 A I -1.1131
32 H I -0.6723
33 F I 0.0000
34 P I 0.0000
35 A I 0.0000
36 H I -0.5959
37 S I -0.7980
38 M I -0.8138
39 G I -1.3800
40 P I -1.2597
41 Q I -0.7937
42 V I -0.4531
43 I I -0.7661
44 R I -1.3766
45 A I -1.0025
46 D I -1.9961
47 G I -1.2990
48 L I -0.2867
49 L I -0.1120
50 V I 0.0000
51 S I 0.0000
52 D I -0.6892
53 L I 0.0000
54 L I 0.0000
55 Q I -1.0858
56 A I 0.0000
57 I I 0.0000
58 I I -0.0772
59 P I -0.1519
60 L I 0.4358
61 F I 0.0000
62 E I -0.6658
63 L I -0.2140
64 D I 0.0000
65 S I -0.2489
66 Y I 0.1034
67 A I -0.0486
68 P I -0.2568
69 P I -0.3409
70 L I 0.0000
71 V I 0.0000
72 M I 0.0000
73 M I 0.0000
74 A I -0.2881
75 A I -0.8597
76 V I 0.0000
77 E I -1.5973
78 G I -0.8635
79 D I -0.7566
80 T I -0.7958
81 L I -1.2877
82 D I -2.7791
83 P I -2.5330
84 E I -3.1333
85 V I 0.0000
86 E I -2.6915
87 R I -3.6894
88 R I -2.6290
89 Y I 0.0000
90 R I -2.4326
91 N I -2.4542
92 A I 0.0000
93 L I 0.0000
94 S I -0.9267
95 L I -0.3462
96 Q I -1.0657
97 A I -0.6093
98 P I -0.8279
99 C I 0.0000
100 P I -0.6556
101 D I -0.8357
102 I I 0.0000
103 I I 0.2963
104 R I -0.0273
105 I I 0.1180
106 N I -0.2456
107 R I 0.0000
108 F I 1.1141
109 A I 0.6544
110 F I 0.0000
111 Y I 0.4986
112 L I 0.8190 mutated: EI112L
113 R I -0.5046
114 A I 0.0000
115 Q I -1.7035
116 K I -2.1906
117 A I 0.0000
118 F I 0.0000
119 A I 0.0000
120 I I 0.0000
121 V I 0.0000
122 I I 0.0000
123 T I 0.0000
124 G I 0.0000
125 E I 0.0000
126 R I -2.0679
127 A I -1.7355
128 K I -1.6240
129 Y I 0.0000
130 G I 0.0000
131 N I 0.0000
132 I I 0.0000
133 L I 0.0000
134 L I 0.0000
135 K I -0.4368
136 K I 0.0000
137 G I 0.0000
138 V I -0.4494
139 T I -0.4639
140 P I -0.5866
1 M J 1.3116
2 L J 0.8562
3 K J -0.8513
4 T J -0.3226
5 I J 0.5681
6 S J 0.1742
7 P J 0.5419
8 L J 0.7487
9 I J 0.0000
10 S J -0.6595
11 P J -1.1148
12 E J -2.4240
13 L J 0.0000
14 L J -1.1766
15 K J -2.4256
16 V J 0.0000
17 L J 0.0000
18 A J -0.8245
19 E J -1.1554
20 M J 0.0000
21 G J 0.0000
22 H J 0.0000
23 G J -0.4614
24 D J 0.0000
25 E J -0.5965
26 I J 0.0000
27 I J 0.0000
28 F J 0.0000
29 S J 0.0000
30 D J 0.0000
31 A J -1.1040
32 H J -0.6903
33 F J 0.0000
34 P J 0.0000
35 A J 0.0000
36 H J -0.5540
37 S J -0.7909
38 M J 0.0000
39 G J -1.3699
40 P J -1.2052
41 Q J -0.8729
42 V J -0.2937
43 I J -0.8181
44 R J -1.3958
45 A J -1.1293
46 D J -2.1183
47 G J -1.2297
48 L J -0.4604
49 L J -0.2862
50 V J 0.0000
51 S J 0.0000
52 D J -0.7100
53 L J 0.0000
54 L J 0.0000
55 Q J -1.2820
56 A J 0.0000
57 I J 0.0000
58 I J 0.0000
59 P J -0.0441
60 L J 0.7519
61 F J 0.0000
62 E J -0.5667
63 L J 0.0000
64 D J 0.0000
65 S J -0.1712
66 Y J -0.0567
67 A J -0.3031
68 P J -0.4848
69 P J -0.5532
70 L J 0.0000
71 V J 0.0000
72 M J 0.0000
73 M J 0.0000
74 A J -0.1705
75 A J -0.6750
76 V J -0.4485
77 E J -1.9591
78 G J 0.0000
79 D J -1.0060
80 T J -1.1902
81 L J -0.9609
82 D J -2.4987
83 P J -2.3807
84 E J -3.0629
85 V J 0.0000
86 E J 0.0000
87 R J -3.4290
88 R J -2.5647
89 Y J 0.0000
90 R J -2.4163
91 N J -2.0128
92 A J 0.0000
93 L J 0.0000
94 S J -0.5662
95 L J 0.2830
96 Q J -0.6824
97 A J -0.3864
98 P J -0.2847
99 C J -0.6531
100 P J -1.0515
101 D J -1.8453
102 I J 0.0000
103 I J 0.0000
104 R J -0.3557
105 I J 0.0000
106 N J -0.0900
107 R J 0.2954
108 F J 1.5456
109 A J 0.0000
110 F J 0.0000
111 Y J 0.1832
112 L J 0.1217 mutated: EJ112L
113 R J -0.4881
114 A J 0.0000
115 Q J -2.0608
116 K J -2.2964
117 A J 0.0000
118 F J -0.7437
119 A J 0.0000
120 I J 0.0000
121 V J 0.0000
122 I J 0.0000
123 T J 0.0000
124 G J 0.0000
125 E J 0.0000
126 R J -2.0019
127 A J -1.7081
128 K J -1.5723
129 Y J -0.7934
130 G J 0.0000
131 N J 0.0000
132 I J 0.0000
133 L J 0.0000
134 L J 0.0000
135 K J -0.4828
136 K J -0.5022
137 G J 0.0000
138 V J -0.3684
139 T J -0.3950
140 P J -0.6995

 

Laboratory of Theory of Biopolymers 2015