Project name: OspC-N22

Chain sequence(s)	A: MKKNTLSAILMTLFLFISCNNSGKDGNASANSADESVKGPNLTEISKKITESNAVVLAVKEVEALLASIDELAKAIGKKIENNGLDAVANHNGSLLAGAYTISTLITEKINVLSKLKNEELKEKIETAKKCSEAFTKKLKSEHADLGIAQNATDDNAKKAILKTHNTKDKGAKELKKLSESVENLLKAAQEMLANSVKELTSPVVAESPKKP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.3327
• Maximal score value: 0.8181
• Average score: -1.1441
• Total score value: -242.5417

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	-0.1795
2	K	A	-2.0096
3	K	A	-2.3922
4	N	A	-1.7540
5	T	A	-0.9535
6	L	A	-0.5568
7	S	A	-1.0684
8	A	A	-0.9705
9	I	A	-0.4442
10	L	A	0.0000
11	M	A	0.1976
12	T	A	-0.2395
13	L	A	0.0000
14	F	A	0.2347
15	L	A	0.0830
16	F	A	-0.4019
17	I	A	0.0000
18	S	A	-0.3047
19	C	A	-0.0426
20	N	A	-0.9567
21	N	A	-1.7477
22	S	A	-1.1993
23	G	A	0.0000
24	K	A	0.0000
25	D	A	-2.5533
26	G	A	-1.7140
27	N	A	-1.8795
28	A	A	0.0000
29	S	A	-1.6234
30	A	A	0.0000
31	N	A	-2.3021
32	S	A	-2.2622
33	A	A	-2.5990
34	D	A	-3.1918
35	E	A	-3.0147
36	S	A	-1.6711
37	V	A	-0.6349
38	K	A	-1.1680
39	G	A	0.0122
40	P	A	0.0000
41	N	A	-0.8028
42	L	A	-0.5898
43	T	A	-0.9740
44	E	A	-1.7950
45	I	A	0.0000
46	S	A	-1.6501
47	K	A	-2.9164
48	K	A	-2.8254
49	I	A	-1.7922
50	T	A	-1.9851
51	E	A	-2.6940
52	S	A	0.0000
53	N	A	-1.1852
54	A	A	-0.7362
55	V	A	0.0000
56	V	A	0.0000
57	L	A	0.3217
58	A	A	0.0000
59	V	A	0.0000
60	K	A	0.0000
61	E	A	-0.0122
62	V	A	0.0000
63	E	A	-0.3199
64	A	A	0.0000
65	L	A	0.0000
66	L	A	0.0000
67	A	A	-0.7278
68	S	A	-0.8688
69	I	A	0.0000
70	D	A	-1.5791
71	E	A	-2.5269
72	L	A	-1.3270
73	A	A	0.0000
74	K	A	-2.3888
75	A	A	-1.1363
76	I	A	0.0000
77	G	A	-1.4297
78	K	A	-1.2012
79	K	A	-0.3666
80	I	A	0.8181
81	E	A	-1.0858
82	N	A	-1.8634
83	N	A	-1.7507
84	G	A	-0.8886
85	L	A	0.1492
86	D	A	-0.6506
87	A	A	-0.2861
88	V	A	-0.2568
89	A	A	-1.1483
90	N	A	-2.1444
91	H	A	-2.1656
92	N	A	0.0000
93	G	A	-1.2309
94	S	A	-0.6493
95	L	A	-0.2400
96	L	A	0.0000
97	A	A	-0.1193
98	G	A	0.0883
99	A	A	0.0000
100	Y	A	-0.1247
101	T	A	0.3163
102	I	A	0.2904
103	S	A	0.0000
104	T	A	-0.3886
105	L	A	-0.0967
106	I	A	0.0000
107	T	A	-1.3201
108	E	A	-1.8926
109	K	A	-1.0497
110	I	A	0.0000
111	N	A	-1.9370
112	V	A	-0.5224
113	L	A	0.0000
114	S	A	-1.1770
115	K	A	-2.2588
116	L	A	0.0000
117	K	A	-3.6236
118	N	A	-3.8806
119	E	A	-4.3327
120	E	A	-3.9091
121	L	A	0.0000
122	K	A	-4.0485
123	E	A	-3.6543
124	K	A	-2.4198
125	I	A	0.0000
126	E	A	-2.2175
127	T	A	-1.9258
128	A	A	0.0000
129	K	A	-2.1790
130	K	A	-2.0745
131	C	A	-1.9021
132	S	A	0.0000
133	E	A	-1.6346
134	A	A	-1.7328
135	F	A	0.0000
136	T	A	-1.6485
137	K	A	-2.7730
138	K	A	-2.5385
139	L	A	0.0000
140	K	A	-3.0539
141	S	A	-2.1537
142	E	A	-1.9567
143	H	A	-1.9800
144	A	A	-0.6466
145	D	A	-0.8423
146	L	A	0.0000
147	G	A	-0.9825
148	I	A	0.1415
149	A	A	-0.6612
150	Q	A	-1.9335
151	N	A	-2.1659
152	A	A	0.0000
153	T	A	-1.7811
154	D	A	-2.0805
155	D	A	-2.4240
156	N	A	-1.9191
157	A	A	0.0000
158	K	A	-2.1502
159	K	A	-2.3190
160	A	A	0.0000
161	I	A	0.0000
162	L	A	-1.7216
163	K	A	-1.7319
164	T	A	-1.1479
165	H	A	-1.7021
166	N	A	-1.7585
167	T	A	-2.0239
168	K	A	-2.6240
169	D	A	-2.5386
170	K	A	-2.1069
171	G	A	0.0000
172	A	A	0.0000
173	K	A	-3.3521
174	E	A	-2.8026
175	L	A	0.0000
176	K	A	-3.2376
177	K	A	-3.0860
178	L	A	0.0000
179	S	A	-2.2025
180	E	A	-2.5839
181	S	A	0.0000
182	V	A	0.0000
183	E	A	-2.2655
184	N	A	-1.8481
185	L	A	0.0000
186	L	A	0.0000
187	K	A	-2.1377
188	A	A	-1.6688
189	A	A	0.0000
190	Q	A	-1.7630
191	E	A	-2.1786
192	M	A	-1.6660
193	L	A	0.0000
194	A	A	0.0000
195	N	A	-1.7786
196	S	A	0.0000
197	V	A	0.0000
198	K	A	-2.6196
199	E	A	-2.1322
200	L	A	0.0000
201	T	A	-2.3005
202	S	A	-1.2175
203	P	A	-0.6824
204	V	A	0.6421
205	V	A	0.7964
206	A	A	-0.1423
207	E	A	-1.4224
208	S	A	-1.7921
209	P	A	-2.3619
210	K	A	-3.0366
211	K	A	-2.8178
212	P	A	-1.7234