Project name: OspC-C02

Chain sequence(s)	A: MKKNTLSAILMTLFLFISCNNSGKDGNASANSADESVKGPNLTEISKKITESNAVVLAVKEVETLLSSIDELAKAIGKKIENNGLGAVANHNGSLLAGAYAISTLITEKLSGLKNSEELKEKIEKAKKCSEKFTKKLKSSHADLGKQAATDDNAKKAILKTHANKDKGAKELEKLSESVESLSKAAQEMLANSVKELTSPVVAESPKKP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.4341
• Maximal score value: 2.3146
• Average score: -1.2101
• Total score value: -252.9153

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.3108
2	K	A	-0.9798
3	K	A	-1.8129
4	N	A	0.0210
5	T	A	0.0000
6	L	A	1.1172
7	S	A	1.4116
8	A	A	1.2176
9	I	A	1.1562
10	L	A	0.0000
11	M	A	-0.5180
12	T	A	-1.6646
13	L	A	0.0000
14	F	A	0.0000
15	L	A	1.3903
16	F	A	2.3146
17	I	A	1.3470
18	S	A	0.1910
19	C	A	-0.4954
20	N	A	-2.2640
21	N	A	-2.0908
22	S	A	-2.1794
23	G	A	-2.5436
24	K	A	-3.0407
25	D	A	-3.2594
26	G	A	0.0000
27	N	A	-1.5609
28	A	A	-0.9287
29	S	A	-1.4084
30	A	A	-1.1775
31	N	A	-2.0764
32	S	A	-1.9727
33	A	A	-2.3907
34	D	A	-3.2288
35	E	A	-3.1370
36	S	A	-2.0195
37	V	A	-1.3222
38	K	A	-1.7806
39	G	A	-0.5829
40	P	A	0.0000
41	N	A	-1.4886
42	L	A	-1.3157
43	T	A	-1.6655
44	E	A	-2.9345
45	I	A	0.0000
46	S	A	-2.0201
47	K	A	-3.2312
48	K	A	-2.8028
49	I	A	-1.8373
50	T	A	-1.9877
51	E	A	-2.7993
52	S	A	0.0000
53	N	A	-1.0908
54	A	A	-0.7137
55	V	A	0.0000
56	V	A	0.0000
57	L	A	0.7781
58	A	A	0.0000
59	V	A	0.0000
60	K	A	0.0000
61	E	A	0.6968
62	V	A	0.0000
63	E	A	0.0000
64	T	A	0.0000
65	L	A	0.0000
66	L	A	0.0000
67	S	A	0.0000
68	S	A	-0.5024
69	I	A	0.0000
70	D	A	-1.2775
71	E	A	-1.9053
72	L	A	-0.9772
73	A	A	0.0000
74	K	A	-1.9606
75	A	A	-1.0270
76	I	A	0.0000
77	G	A	-1.5102
78	K	A	-1.6217
79	K	A	-1.3932
80	I	A	0.0377
81	E	A	-2.1364
82	N	A	-2.4203
83	N	A	-2.0805
84	G	A	-1.2062
85	L	A	-0.2421
86	G	A	-0.7862
87	A	A	-0.4243
88	V	A	-0.6121
89	A	A	-1.1026
90	N	A	-1.8229
91	H	A	-2.1610
92	N	A	0.0000
93	G	A	-1.5695
94	S	A	-0.7848
95	L	A	-0.1800
96	L	A	0.0000
97	A	A	-0.1734
98	G	A	0.1752
99	A	A	0.0000
100	Y	A	0.0651
101	A	A	0.4851
102	I	A	0.4032
103	S	A	0.0000
104	T	A	-0.4756
105	L	A	-0.1114
106	I	A	0.0000
107	T	A	-1.5741
108	E	A	-2.0183
109	K	A	-1.4345
110	L	A	0.0000
111	S	A	-1.7544
112	G	A	-1.5853
113	L	A	0.0000
114	K	A	-2.8487
115	N	A	-3.2441
116	S	A	-3.1714
117	E	A	-3.9242
118	E	A	-3.6392
119	L	A	0.0000
120	K	A	-4.4341
121	E	A	-4.0452
122	K	A	-3.2843
123	I	A	0.0000
124	E	A	-3.5640
125	K	A	-3.4169
126	A	A	0.0000
127	K	A	-3.2391
128	K	A	-3.4631
129	C	A	-3.0277
130	S	A	0.0000
131	E	A	-3.3522
132	K	A	-3.6319
133	F	A	0.0000
134	T	A	0.0000
135	K	A	-3.5462
136	K	A	-3.3304
137	L	A	0.0000
138	K	A	-3.2602
139	S	A	-2.2781
140	S	A	-2.1208
141	H	A	-2.3220
142	A	A	-1.3088
143	D	A	-1.7104
144	L	A	0.0000
145	G	A	-2.0837
146	K	A	-2.2596
147	Q	A	-2.2709
148	A	A	-1.7486
149	A	A	0.0000
150	T	A	-1.6676
151	D	A	-1.6327
152	D	A	-1.8453
153	N	A	-1.6549
154	A	A	0.0000
155	K	A	-1.7037
156	K	A	-1.8481
157	A	A	0.0000
158	I	A	0.0000
159	L	A	-1.2036
160	K	A	-1.1849
161	T	A	-0.6899
162	H	A	-1.0761
163	A	A	-0.7941
164	N	A	-1.7293
165	K	A	-2.0626
166	D	A	-2.3204
167	K	A	-2.1796
168	G	A	0.0000
169	A	A	0.0000
170	K	A	-2.3867
171	E	A	-2.5580
172	L	A	0.0000
173	E	A	-2.3385
174	K	A	-2.7918
175	L	A	0.0000
176	S	A	0.0000
177	E	A	-3.0727
178	S	A	0.0000
179	V	A	0.0000
180	E	A	-3.0900
181	S	A	-2.2082
182	L	A	0.0000
183	S	A	0.0000
184	K	A	-2.6658
185	A	A	-1.8667
186	A	A	0.0000
187	Q	A	-1.5900
188	E	A	-1.9697
189	M	A	-1.5554
190	L	A	-1.2236
191	A	A	-1.4467
192	N	A	-1.8020
193	S	A	0.0000
194	V	A	-2.0049
195	K	A	-2.9517
196	E	A	-2.0494
197	L	A	-2.0186
198	T	A	-2.1705
199	S	A	-1.2043
200	P	A	-0.1464
201	V	A	1.1859
202	V	A	1.4589
203	A	A	0.1069
204	E	A	-1.9176
205	S	A	-0.9409
206	P	A	-1.6188
207	K	A	-3.0242
208	K	A	-3.1397
209	P	A	-1.7610