| Chain sequence(s) |
A: HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE I: VNV B: MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 58 | H | A | -0.8533 | |
| 59 | P | A | -0.5823 | |
| 60 | W | A | 0.0000 | |
| 61 | F | A | 0.4180 | |
| 62 | F | A | 0.2881 | |
| 63 | G | A | -0.5158 | |
| 64 | K | A | -2.3435 | |
| 65 | I | A | 0.0000 | |
| 66 | P | A | -2.5538 | |
| 67 | R | A | -3.2872 | |
| 68 | A | A | -2.0467 | |
| 69 | K | A | -2.7288 | |
| 70 | A | A | 0.0000 | |
| 71 | E | A | -2.8504 | |
| 72 | E | A | -3.1127 | |
| 73 | M | A | -1.9292 | |
| 74 | L | A | 0.0000 | |
| 75 | S | A | -3.1105 | |
| 76 | K | A | -2.9676 | |
| 77 | Q | A | -2.7928 | |
| 78 | R | A | -3.3002 | |
| 79 | H | A | -3.2693 | |
| 80 | D | A | -2.4876 | |
| 81 | G | A | 0.0000 | |
| 82 | A | A | 0.0000 | |
| 83 | F | A | 0.0000 | |
| 84 | L | A | 0.0000 | |
| 85 | I | A | 0.0000 | |
| 86 | R | A | 0.0000 | |
| 87 | E | A | -1.7585 | |
| 88 | S | A | 0.0000 | |
| 89 | E | A | -2.8969 | |
| 90 | S | A | -1.5374 | |
| 91 | A | A | -1.0930 | |
| 92 | P | A | -1.1704 | |
| 93 | G | A | -1.0290 | |
| 94 | D | A | -1.1010 | |
| 95 | F | A | -0.7603 | |
| 96 | S | A | -0.8563 | |
| 97 | L | A | 0.0000 | |
| 98 | S | A | 0.0000 | |
| 99 | V | A | 0.0000 | |
| 100 | K | A | -2.0232 | |
| 101 | F | A | -1.8053 | |
| 102 | G | A | -2.1387 | |
| 103 | N | A | -2.6524 | |
| 104 | D | A | -2.7741 | |
| 105 | V | A | 0.0000 | |
| 106 | Q | A | -0.5199 | |
| 107 | H | A | -0.2593 | |
| 108 | F | A | 0.0000 | |
| 109 | K | A | -0.0997 | |
| 110 | V | A | 0.0000 | |
| 111 | L | A | -0.3408 | |
| 112 | R | A | -1.9084 | |
| 113 | D | A | -1.5504 | |
| 114 | G | A | -1.1137 | |
| 115 | A | A | -0.9300 | |
| 116 | G | A | -1.3271 | |
| 117 | K | A | -1.6489 | |
| 118 | Y | A | -1.1290 | |
| 119 | F | A | 0.0000 | |
| 120 | L | A | 0.0000 | |
| 121 | W | A | 0.9416 | |
| 122 | V | A | 2.1131 | |
| 123 | V | A | 1.2432 | |
| 124 | K | A | -0.2085 | |
| 125 | F | A | -1.1872 | |
| 126 | N | A | -1.9202 | |
| 127 | S | A | -1.4996 | |
| 128 | L | A | -1.0699 | |
| 129 | N | A | -2.0833 | |
| 130 | E | A | -2.6902 | |
| 131 | L | A | 0.0000 | |
| 132 | V | A | 0.0000 | |
| 133 | D | A | -2.4969 | |
| 134 | Y | A | -1.0631 | |
| 135 | H | A | 0.0000 | |
| 136 | R | A | -1.2722 | |
| 137 | S | A | -0.6310 | |
| 138 | T | A | -0.3956 | |
| 139 | S | A | -0.9340 | |
| 140 | V | A | 0.0000 | |
| 141 | S | A | -1.6885 | |
| 142 | R | A | -2.7456 | |
| 143 | N | A | -2.7115 | |
| 144 | Q | A | -2.2198 | |
| 145 | Q | A | -2.0908 | |
| 146 | I | A | 0.0000 | |
| 147 | F | A | -0.8956 | |
| 148 | L | A | 0.0000 | |
| 149 | R | A | -2.6147 | |
| 150 | D | A | -2.2316 | |
| 151 | I | A | -1.8220 | |
| 152 | E | A | -2.4020 | |
| 55 | M | B | 0.0937 | |
| 56 | K | B | -1.5019 | |
| 57 | P | B | -1.0575 | |
| 58 | H | B | -1.0564 | |
| 59 | P | B | -0.7865 | |
| 60 | W | B | 0.0000 | |
| 61 | F | B | 0.6418 | |
| 62 | F | B | 0.4134 | |
| 63 | G | B | -0.5231 | |
| 64 | K | B | -2.3119 | |
| 65 | I | B | -1.7266 | |
| 66 | P | B | -2.4564 | |
| 67 | R | B | -3.1875 | |
| 68 | A | B | -1.9138 | |
| 69 | K | B | -2.2515 | |
| 70 | A | B | 0.0000 | |
| 71 | E | B | -2.6928 | |
| 72 | E | B | -2.9484 | |
| 73 | M | B | -1.5989 | |
| 74 | L | B | 0.0000 | |
| 75 | S | B | -2.9404 | |
| 76 | K | B | -2.8362 | |
| 77 | Q | B | 0.0000 | |
| 78 | R | B | -2.9570 | |
| 79 | H | B | -2.5670 | |
| 80 | D | B | -2.5753 | |
| 81 | G | B | 0.0000 | |
| 82 | A | B | 0.0000 | |
| 83 | F | B | 0.0000 | |
| 84 | L | B | 0.0000 | |
| 85 | I | B | 0.0000 | |
| 86 | R | B | 0.0000 | |
| 87 | E | B | -1.9895 | |
| 88 | S | B | 0.0000 | |
| 89 | E | B | -2.9745 | |
| 90 | S | B | -1.6302 | |
| 91 | A | B | -1.3057 | |
| 92 | P | B | -1.5045 | |
| 93 | G | B | -1.1982 | |
| 94 | D | B | -1.4465 | |
| 95 | F | B | -0.9726 | |
| 96 | S | B | 0.0000 | |
| 97 | L | B | 0.0000 | |
| 98 | S | B | 0.0000 | |
| 99 | V | B | 0.0000 | |
| 100 | K | B | -2.0555 | |
| 101 | F | B | -1.8348 | |
| 102 | G | B | -2.1258 | |
| 103 | N | B | -2.6363 | |
| 104 | D | B | -2.7674 | |
| 105 | V | B | -1.7903 | |
| 106 | Q | B | -0.8328 | |
| 107 | H | B | -1.2245 | |
| 108 | F | B | -0.6396 | |
| 109 | K | B | -1.5264 | |
| 110 | V | B | 0.0000 | |
| 111 | L | B | -0.1503 | |
| 112 | R | B | -1.3638 | |
| 113 | D | B | -1.2351 | |
| 114 | G | B | -1.0153 | |
| 115 | A | B | -0.8548 | |
| 116 | G | B | -1.1316 | |
| 117 | K | B | -1.3650 | |
| 118 | Y | B | -0.8910 | |
| 119 | F | B | 0.0000 | |
| 120 | L | B | 0.0000 | |
| 121 | W | B | 1.2519 | |
| 122 | V | B | 2.4678 | |
| 123 | V | B | 1.3513 | |
| 124 | K | B | -0.2372 | |
| 125 | F | B | -1.0222 | |
| 126 | N | B | -1.9026 | |
| 127 | S | B | -1.2386 | |
| 128 | L | B | -0.8676 | |
| 129 | N | B | -1.5579 | |
| 130 | E | B | -1.9684 | |
| 131 | L | B | 0.0000 | |
| 132 | V | B | 0.0000 | |
| 133 | D | B | -2.0535 | |
| 134 | Y | B | -0.7940 | |
| 135 | H | B | 0.0000 | |
| 136 | R | B | -1.1543 | |
| 137 | S | B | -0.6600 | |
| 138 | T | B | -0.3601 | |
| 139 | S | B | -0.9176 | |
| 140 | V | B | 0.0000 | |
| 141 | S | B | 0.0000 | |
| 142 | R | B | -2.5658 | |
| 143 | N | B | -2.5247 | |
| 144 | Q | B | -2.2227 | |
| 145 | Q | B | -2.0115 | |
| 146 | I | B | 0.0000 | |
| 147 | F | B | -0.3906 | |
| 148 | L | B | 0.0000 | |
| 149 | R | B | -2.6633 | |
| 150 | D | B | -2.8246 | |
| 151 | I | B | -2.2806 | |
| 152 | E | B | -2.6296 | |
| 1 | V | I | 1.6720 | |
| 2 | N | I | 1.3808 | |
| 3 | V | I | 2.1232 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine