Project name: b1b81e537fcfec

Chain sequence(s)	A: RMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCVASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0598
• Maximal score value: 1.5301
• Average score: -0.8466
• Total score value: -178.6391

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1649	R	A	-2.0380
1650	M	A	-1.1376
1651	S	A	-0.9232
1652	M	A	0.0000
1653	V	A	0.0000
1654	V	A	0.0000
1655	S	A	0.0000
1656	G	A	-1.0562
1657	L	A	-0.5854
1658	T	A	-0.8275
1659	P	A	-0.9227
1660	E	A	-1.4979
1661	E	A	-0.8377
1662	F	A	-0.1855
1663	M	A	0.3272
1664	L	A	0.0936
1665	V	A	0.0000
1666	Y	A	-0.3376
1667	K	A	-1.6545
1668	F	A	0.0000
1669	A	A	0.0000
1670	R	A	-3.2659
1671	K	A	-3.2664
1672	H	A	-2.4411
1673	H	A	-2.3796
1674	I	A	0.0000
1675	T	A	-0.6831
1676	L	A	-0.1339
1677	T	A	-0.0131
1678	N	A	-0.4607
1679	L	A	0.9043
1680	I	A	0.0000
1681	T	A	-1.3316
1682	E	A	-2.7204
1683	E	A	-2.9625
1684	T	A	0.0000
1685	T	A	-1.0542
1686	H	A	0.0000
1687	V	A	0.0000
1688	V	A	0.0000
1689	M	A	0.0000
1690	K	A	-1.0593
1691	T	A	0.0000
1692	D	A	-1.2621
1693	A	A	-1.0728
1694	E	A	-2.5777
1695	F	A	-1.6891
1696	V	A	0.0000
1697	C	A	0.0000
1698	E	A	-1.4398
1699	R	A	-0.6555
1700	T	A	-0.8364
1701	L	A	-0.3420
1702	K	A	-0.0453
1703	Y	A	0.0000
1704	F	A	0.0000
1705	L	A	0.0000
1706	G	A	0.0000
1707	I	A	0.0000
1708	A	A	0.0000
1709	G	A	-0.8673
1710	G	A	-0.9682
1711	K	A	0.0000
1712	W	A	-0.2739
1713	V	A	0.0000
1714	V	A	0.0000
1715	S	A	0.0000
1716	Y	A	0.0000
1717	F	A	0.1146
1718	W	A	0.0000
1719	V	A	0.0000
1720	T	A	-0.7941
1721	Q	A	-1.7520
1722	S	A	0.0000
1723	I	A	-2.3087
1724	K	A	-3.4481
1725	E	A	-4.0598
1726	R	A	-3.9054
1727	K	A	-3.3756
1728	M	A	-1.4545
1729	L	A	-1.6713
1730	N	A	-2.1745
1731	E	A	-1.7796
1732	H	A	-2.4410
1733	D	A	-2.6344
1734	F	A	0.0000
1735	E	A	0.0000
1736	V	A	0.0000
1737	R	A	-2.8736
1738	G	A	0.0000
1739	D	A	0.0000
1740	V	A	1.3129
1741	V	A	1.5301
1742	N	A	0.1108
1743	G	A	-0.9281
1744	R	A	-2.5643
1745	N	A	-2.9950
1746	H	A	-2.0147
1747	Q	A	-2.2084
1748	G	A	0.0000
1749	P	A	0.0000
1750	K	A	-2.3375
1751	R	A	-2.2866
1752	A	A	0.0000
1753	R	A	-2.1263
1754	E	A	-3.2169
1755	S	A	-2.9922
1756	Q	A	-2.6877
1757	D	A	-3.5027
1758	R	A	-3.5846
1759	K	A	-2.7526
1760	I	A	-1.3903
1761	F	A	0.0000
1762	R	A	-2.6560
1763	G	A	-1.4309
1764	L	A	-0.9120
1765	E	A	-0.5971
1766	I	A	0.0000
1767	C	A	0.0000
1768	C	A	0.0000
1769	Y	A	-0.4327
1770	G	A	-0.1113
1771	P	A	-0.3604
1772	F	A	-0.5087
1773	T	A	-0.8827
1774	N	A	-1.2482
1775	M	A	0.0000
1776	P	A	-1.1327
1777	T	A	-1.2384
1778	D	A	-1.9617
1779	Q	A	-1.2350
1780	L	A	0.0000
1781	E	A	-1.2784
1782	W	A	-0.7215
1783	M	A	0.0000
1784	V	A	0.0000
1785	Q	A	-1.0173
1786	L	A	-0.6890
1787	C	A	0.0000
1788	V	A	-1.4339
1789	A	A	0.0000
1790	S	A	-0.7295
1791	V	A	-0.7406
1792	V	A	0.0000
1793	K	A	-2.5239
1794	E	A	-2.6464
1795	L	A	0.0000
1796	S	A	-1.1201
1797	S	A	-0.9849
1798	F	A	-0.4670
1799	T	A	0.5387
1800	L	A	1.0441
1801	G	A	0.1588
1802	T	A	-0.1861
1803	G	A	-0.4022
1804	V	A	0.0203
1805	H	A	-0.4815
1806	P	A	-0.4412
1807	I	A	0.0000
1808	V	A	0.0000
1809	V	A	0.0000
1810	V	A	0.0000
1811	Q	A	0.0000
1812	P	A	-1.2394
1813	D	A	-1.7754
1814	A	A	-1.1030
1815	W	A	-1.4620
1816	T	A	-1.9270
1817	E	A	-2.7147
1818	D	A	-2.5633
1819	N	A	-2.3100
1820	G	A	-1.1953
1821	F	A	-0.3981
1822	H	A	-0.4476
1823	A	A	-0.2867
1824	I	A	0.0000
1825	G	A	-0.8688
1826	Q	A	-1.0486
1827	M	A	-0.3160
1828	C	A	0.0000
1829	E	A	-1.7719
1830	A	A	-1.1037
1831	P	A	-0.6316
1832	V	A	0.0000
1833	V	A	0.0000
1834	T	A	-0.4080
1835	R	A	-0.6657
1836	E	A	-1.1483
1837	W	A	0.0000
1838	V	A	0.0000
1839	L	A	0.0000
1840	D	A	-0.5163
1841	S	A	0.0000
1842	V	A	0.0000
1843	A	A	0.0000
1844	L	A	-0.7632
1845	Y	A	0.0000
1846	Q	A	-1.3522
1847	C	A	-0.9125
1848	Q	A	-1.5160
1849	E	A	-2.3179
1850	L	A	-1.3081
1851	D	A	-2.0188
1852	T	A	-1.0529
1853	Y	A	-0.5990
1854	L	A	-0.0481
1855	I	A	0.0000
1856	P	A	0.1347
1857	Q	A	0.1536
1858	I	A	1.1651
1859	P	A	0.1797