Project name: b45517792ce4b67

Chain sequence(s)	A: IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVSHLVGITSWGEGCAQRERPGVYTNVVEYVDWILEKTQV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.4037
• Maximal score value: 1.6007
• Average score: -1.0065
• Total score value: -238.5304

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
16	I	A	0.0000
17	V	A	-1.7878
18	G	A	-1.5682
19	G	A	-1.0860
20	T	A	-0.3939
21	A	A	0.2079
22	S	A	0.0000
23	V	A	0.6132
24	R	A	-1.4900
25	G	A	-1.7892
26	E	A	-0.9872
27	W	A	0.0000
28	P	A	-1.5846
29	W	A	0.0000
30	Q	A	0.0000
31	V	A	0.0000
32	T	A	0.0000
33	L	A	0.0000
34	H	A	0.0000
35	T	A	0.0000
36	T	A	-1.0053
37	S	A	-0.7387
37A	P	A	-0.6529
37B	T	A	-0.7937
37C	Q	A	-1.2727
37D	R	A	-1.3510
38	H	A	-0.5851
39	L	A	-0.1065
40	C	A	0.0000
41	G	A	0.0000
42	G	A	0.0000
43	S	A	0.0000
44	I	A	0.0000
45	I	A	-0.0700
46	G	A	-0.5655
47	N	A	-1.3296
48	Q	A	-1.4214
51	W	A	-1.0009
52	I	A	0.0000
53	L	A	0.0000
54	T	A	0.0000
55	A	A	0.0000
56	A	A	0.0000
57	H	A	-0.0416
58	C	A	0.0000
59	F	A	0.0000
59A	Y	A	0.8694
59B	G	A	-0.1861
59C	V	A	-0.6203
60	E	A	-1.8934
61	S	A	-1.7935
62	P	A	-1.9925
63	K	A	-2.5150
64	I	A	0.0000
65	L	A	0.0000
66	R	A	-0.9429
67	V	A	0.0000
68	Y	A	0.0000
69	S	A	-0.1301
70	G	A	-0.7586
71	I	A	-0.4039
72	L	A	-0.4570
73	N	A	-0.9477
74	Q	A	-1.2046
75	S	A	-1.3550
76	E	A	-1.8731
77	I	A	-1.9007
78	K	A	-3.4623
79	E	A	-3.6187
80	D	A	-3.1775
81	T	A	-2.0814
81A	S	A	-0.8203
82	F	A	0.3244
83	F	A	-0.3803
84	G	A	-1.5256
85	V	A	0.0000
86	Q	A	-3.0154
87	E	A	-2.4677
88	I	A	-0.4432
89	I	A	-0.2683
90	I	A	-0.1432
91	H	A	-1.1090
92	D	A	-2.3829
93	Q	A	-2.2498
94	Y	A	-1.5746
95	K	A	-2.1710
96	M	A	-1.1102
97	A	A	0.0000
98	E	A	-2.2035
99	S	A	-1.7199
100	G	A	0.0000
101	Y	A	-0.8574
102	D	A	0.0000
103	I	A	0.0000
104	A	A	0.0000
105	L	A	0.0000
106	L	A	0.0000
107	K	A	-2.0555
108	L	A	0.0000
109	E	A	-2.6523
110	T	A	-1.3748
111	T	A	-1.0958
112	V	A	0.0000
113	N	A	-1.4584
114	Y	A	-1.1554
115	T	A	-1.5158
116	D	A	-2.5900
117	S	A	-2.0219
118	Q	A	-1.8241
119	R	A	-2.3520
121	P	A	-0.7238
122	I	A	0.0000
123	C	A	0.5305
124	L	A	0.3360
125	P	A	0.0000
126	S	A	-1.8309
127	K	A	-3.1470
128	G	A	-2.4638
129	D	A	-2.5653
130	R	A	-3.2691
131	N	A	-1.9568
132	V	A	-0.0124
132A	I	A	1.6007
133	Y	A	0.0000
134	T	A	-0.2013
135	D	A	-1.1267
136	C	A	0.0000
137	W	A	-0.5602
138	V	A	0.0000
139	T	A	0.0000
140	G	A	0.0000
141	W	A	0.0000
142	G	A	0.0000
143	Y	A	-2.5113
144	R	A	-3.3846
145	K	A	-3.3121
146	L	A	-2.0484
147	R	A	-2.9204
148	D	A	-2.9998
149	K	A	-2.8857
151	I	A	-1.6122
152	Q	A	-1.3169
153	N	A	-1.3468
154	T	A	-0.6128
155	L	A	0.0000
156	Q	A	-0.4730
157	K	A	-0.4774
158	A	A	0.0000
159	K	A	-1.2054
160	I	A	0.0000
161	P	A	-0.4318
162	L	A	0.5447
163	V	A	-0.0921
164	T	A	-0.8907
165	N	A	-1.9726
166	E	A	-2.9594
167	E	A	-2.4956
168	C	A	0.0000
169	Q	A	-3.3233
170	K	A	-3.7030
171	R	A	-3.3052
172	Y	A	0.0000
173	R	A	-3.3246
173A	G	A	-2.3197
174	H	A	-2.8059
175	K	A	-2.8946
176	I	A	0.0000
177	T	A	-1.5340
178	H	A	-1.9589
179	K	A	-1.1169
180	M	A	0.0000
181	I	A	-0.1517
182	C	A	0.0000
183	A	A	0.0000
184	G	A	0.0000
184A	Y	A	-2.1742
185	R	A	-3.7070
186	E	A	-3.7370
187	G	A	-3.1949
188	G	A	-1.9000
188A	K	A	-1.9520
189	D	A	0.0000
190	A	A	-0.9625
191	C	A	0.0000
192	K	A	-2.5102
193	G	A	-1.1519
194	D	A	0.0000
195	S	A	-0.3560
196	G	A	0.0000
197	G	A	0.0000
198	P	A	0.0000
198A	L	A	0.0000
198B	S	A	0.0000
201	C	A	0.0000
202	K	A	-1.9410
202A	H	A	-2.1049
202B	N	A	-2.2884
202C	E	A	-2.3810
202D	V	A	-0.6897
203	S	A	-0.6525
204	H	A	-0.2059
209	L	A	0.0000
210	V	A	0.0000
211	G	A	0.0000
212	I	A	0.0000
213	T	A	0.0000
214	S	A	0.0000
215	W	A	-0.7010
216	G	A	-1.1995
217	E	A	-1.6070
218	G	A	-1.2831
219	C	A	-1.7373
220	A	A	-2.4951
221	Q	A	-3.2753
222	R	A	-4.4037
223	E	A	-4.3093
224	R	A	-3.2455
225	P	A	0.0000
226	G	A	0.0000
227	V	A	0.0000
228	Y	A	0.0000
229	T	A	0.0000
230	N	A	-0.7699
231	V	A	0.0000
232	V	A	0.0000
233	E	A	-1.6159
234	Y	A	0.0000
235	V	A	0.0000
236	D	A	-1.7161
237	W	A	-1.0811
238	I	A	0.0000
239	L	A	-0.2733
240	E	A	-2.0189
241	K	A	-1.6067
242	T	A	-0.8568
243	Q	A	-0.7413
244	V	A	1.0072