Project name: b9a774d099fd14a

Chain sequence(s)	H: EVQLQQSGAELVKPGASVKLSCTASGFNIKDTYVHWVKQRPEQGLEWIGRIDPANGYTKYDPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYYCVRPLYDYYAMDYWGQGTSVTVSS; L: DILMTQSPSSMSVSLGDTVSITCHASQGISSNIGWLQQKPGKSFKGLIYYGTNLVDGVPSRFSGSGSGADYSLTISSLESEDFADYYCVQYAQLPYTFGGGTKLEIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.901
• Maximal score value: 1.5255
• Average score: -0.6054
• Total score value: -136.814

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.7651
2	I	L	0.0000
3	L	L	0.6013
4	M	L	0.1327
5	T	L	-0.2995
6	Q	L	0.0000
7	S	L	-0.6356
8	P	L	-0.5611
9	S	L	-0.7809
10	S	L	-1.1474
11	M	L	-0.7536
12	S	L	-0.7826
13	V	L	-0.3216
14	S	L	-0.3023
15	L	L	0.1613
16	G	L	-0.6844
17	D	L	-0.9462
18	T	L	-0.7054
19	V	L	0.0000
20	S	L	-0.2112
21	I	L	0.0000
22	T	L	-0.6873
23	C	L	0.0000
24	H	L	-1.4343
25	A	L	-0.9400
26	S	L	-0.9487
27	Q	L	-1.9536
28	G	L	-1.7676
29	I	L	0.0000
30	S	L	-0.8700
31	S	L	-0.4649
32	N	L	-0.2350
33	I	L	0.0000
34	G	L	0.0000
35	W	L	0.0000
36	L	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	K	L	-1.9130
40	P	L	-1.6357
41	G	L	-1.5160
42	K	L	-2.5066
43	S	L	-1.6639
44	F	L	0.0000
45	K	L	-1.1461
46	G	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	0.6171
50	Y	L	0.8169
51	G	L	0.0000
52	T	L	-0.1341
53	N	L	-0.3073
54	L	L	-0.3085
55	V	L	0.0000
56	D	L	-1.7993
57	G	L	-1.4241
58	V	L	0.0000
59	P	L	-0.6796
60	S	L	-0.4857
61	R	L	-0.7849
62	F	L	0.0000
63	S	L	-0.4392
64	G	L	-0.2466
65	S	L	-0.7181
66	G	L	-1.3118
67	S	L	-1.3619
68	G	L	-1.7149
69	A	L	-2.0244
70	D	L	-2.6116
71	Y	L	0.0000
72	S	L	-0.7875
73	L	L	0.0000
74	T	L	-0.3114
75	I	L	0.0000
76	S	L	-0.9297
77	S	L	-0.9729
78	L	L	0.0000
79	E	L	-2.1181
80	S	L	-1.4916
81	E	L	-2.3984
82	D	L	0.0000
83	F	L	0.0000
84	A	L	0.0000
85	D	L	-1.2227
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	V	L	0.0000
90	Q	L	0.0000
91	Y	L	0.0000
92	A	L	-0.7526
93	Q	L	-1.1010
94	L	L	-0.6328
95	P	L	-0.7157
96	Y	L	0.0000
97	T	L	-0.0408
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-1.1687
101	G	L	-0.9569
102	T	L	0.0000
103	K	L	-2.0330
104	L	L	0.0000
105	E	L	-1.5610
106	I	L	0.0869
107	K	L	-1.1011
1	E	H	-1.9143
2	V	H	-1.1089
3	Q	H	-1.3710
4	L	H	0.0000
5	Q	H	-1.3576
6	Q	H	0.0000
7	S	H	-1.0222
8	G	H	-1.0239
9	A	H	-0.4403
10	E	H	-0.7764
11	L	H	0.6194
12	V	H	-0.3786
13	K	H	-1.6382
14	P	H	-1.3485
15	G	H	-1.0950
16	A	H	-0.7106
17	S	H	-0.9140
18	V	H	0.0000
19	K	H	-2.1316
20	L	H	0.0000
21	S	H	-0.6390
22	C	H	0.0000
23	T	H	-0.7517
24	A	H	0.0000
25	S	H	-1.1457
26	G	H	-1.2702
27	F	H	-1.5755
28	N	H	-2.3471
29	I	H	0.0000
30	K	H	-2.8581
31	D	H	-2.6852
32	T	H	-0.9422
33	Y	H	-0.0574
34	V	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	K	H	0.0000
39	Q	H	-0.7517
40	R	H	-1.6202
41	P	H	-1.6529
42	E	H	-2.9010
43	Q	H	-2.6364
44	G	H	0.0000
45	L	H	0.0000
46	E	H	-0.9007
47	W	H	0.0000
48	I	H	0.0000
49	G	H	0.0000
50	R	H	0.0000
51	I	H	0.0000
52	D	H	-1.0086
52A	P	H	0.0000
53	A	H	-1.5344
54	N	H	-1.2994
55	G	H	-0.6126
56	Y	H	0.4342
57	T	H	-0.2914
58	K	H	-1.2066
59	Y	H	-1.2515
60	D	H	0.0000
61	P	H	-1.7847
62	K	H	-2.2596
63	F	H	0.0000
64	Q	H	-2.2069
65	G	H	-1.4717
66	K	H	-1.3707
67	A	H	0.0000
68	T	H	-0.9188
69	I	H	0.0000
70	T	H	-0.1084
71	A	H	-0.6301
72	D	H	-0.9687
73	T	H	-1.4740
74	S	H	-0.8643
75	S	H	-0.7566
76	N	H	-1.1664
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.3977
80	L	H	0.0000
81	Q	H	-1.3538
82	L	H	0.0000
82A	S	H	-0.8852
82B	S	H	-0.8257
82C	L	H	0.0000
83	T	H	-1.2697
84	S	H	-1.4565
85	E	H	-2.3519
86	D	H	0.0000
87	T	H	-0.4566
88	A	H	0.0000
89	V	H	0.1030
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	V	H	0.0000
94	R	H	0.0940
95	P	H	0.0000
96	L	H	0.6567
97	Y	H	1.4317
98	D	H	1.0442
99	Y	H	1.5255
100	Y	H	0.0000
100A	A	H	0.0000
100B	M	H	0.0000
101	D	H	0.0000
102	Y	H	-0.2211
103	W	H	0.0000
104	G	H	0.0000
105	Q	H	-1.8735
106	G	H	-1.0392
107	T	H	0.0000
108	S	H	-0.2571
109	V	H	0.0000
110	T	H	-0.1923
111	V	H	0.0000
112	S	H	-0.5172
113	S	H	-0.6624