Project name: bb3ee14d43c0694

Chain sequence(s)	A: MTQGDLLSPKRLRGVLLDVDGTLADSNMAHARAWAAALRDEGFEQSPEAILPLIGMGGDKLVPELTGLDAESERGQRLTDGWARHFRALIPDLRPTPGARALLEGLRARGLRVALATSGEAEVVDALLQQIGLDDLELERVSSSDVENSKPDPDLVQAGLRTLGLPAEATLMVGDTPYDAEAARKAGVPCVLLRCGGHPGVEEHDPVYDHPQALLEALDQAFPVE
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5418
• Maximal score value: 1.079
• Average score: -1.0144
• Total score value: -228.2477

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.0000
2	T	A	-1.8256
3	Q	A	-1.9426
4	G	A	-1.6025
5	D	A	-1.8572
6	L	A	-0.4936
7	L	A	-0.4871
8	S	A	0.0000
9	P	A	-1.6975
10	K	A	-2.4403
11	R	A	-2.9409
12	L	A	0.0000
13	R	A	-2.0747
14	G	A	0.0000
15	V	A	0.0000
16	L	A	0.0000
17	L	A	0.0000
18	D	A	0.0000
19	V	A	0.0000
20	D	A	-0.2245
21	G	A	0.0000
22	T	A	0.0000
23	L	A	0.0000
24	A	A	0.0000
25	D	A	-0.9887
26	S	A	0.0000
27	N	A	0.0000
28	M	A	0.4335
29	A	A	0.0000
30	H	A	-0.2616
31	A	A	0.0000
32	R	A	-0.8632
33	A	A	0.0000
34	W	A	0.0000
35	A	A	0.0000
36	A	A	-1.7543
37	A	A	0.0000
38	L	A	0.0000
39	R	A	-3.5372
40	D	A	-3.2865
41	E	A	-2.5496
42	G	A	-2.3380
43	F	A	-2.0767
44	E	A	-2.5597
45	Q	A	0.0000
46	S	A	-1.5391
47	P	A	-1.2630
48	E	A	-1.9157
49	A	A	-1.0241
50	I	A	0.0000
51	L	A	-0.4503
52	P	A	-0.2948
53	L	A	-0.0550
54	I	A	0.0000
55	G	A	-0.0017
56	M	A	-0.5672
57	G	A	-1.1342
58	G	A	-1.4604
59	D	A	-3.3248
60	K	A	-2.7270
61	L	A	0.0000
62	V	A	0.0000
63	P	A	-2.0825
64	E	A	-2.3102
65	L	A	-1.0353
66	T	A	-0.5350
67	G	A	-0.6038
68	L	A	-0.0103
69	D	A	-2.2740
70	A	A	-2.6256
71	E	A	-3.0064
72	S	A	-2.9128
73	E	A	-3.4498
74	R	A	-3.1833
75	G	A	-3.3580
76	Q	A	-3.5418
77	R	A	-3.5374
78	L	A	0.0000
79	T	A	-2.1748
80	D	A	-2.4075
81	G	A	-2.1368
82	W	A	-1.5840
83	A	A	-2.1870
84	R	A	-2.5150
85	H	A	-1.6237
86	F	A	0.0000
87	R	A	-2.5081
88	A	A	-1.0743
89	L	A	-0.3919
90	I	A	-0.3599
91	P	A	-0.8581
92	D	A	-1.6285
93	L	A	0.0000
94	R	A	-1.7507
95	P	A	-1.3526
96	T	A	0.0000
97	P	A	-0.8790
98	G	A	-0.9596
99	A	A	0.0000
100	R	A	-1.1967
101	A	A	-0.9703
102	L	A	0.0000
103	L	A	0.0000
104	E	A	-1.1865
105	G	A	-1.3744
106	L	A	0.0000
107	R	A	-1.4895
108	A	A	-1.2073
109	R	A	-1.9711
110	G	A	-1.6009
111	L	A	0.0000
112	R	A	-1.1753
113	V	A	0.0000
114	A	A	0.0000
115	L	A	0.0000
116	A	A	0.0000
117	T	A	0.0000
118	S	A	-0.8848
119	G	A	-1.2566
120	E	A	-2.5669
121	A	A	-2.2468
122	E	A	-2.7905
123	V	A	-1.8495
124	V	A	0.0000
125	D	A	-2.7109
126	A	A	-1.8873
127	L	A	0.0000
128	L	A	-0.9093
129	Q	A	-1.6907
130	Q	A	-1.9017
131	I	A	0.0000
132	G	A	-0.1911
133	L	A	1.0790
134	D	A	0.0000
135	D	A	0.1750
136	L	A	0.3601
137	E	A	-1.0230
138	L	A	0.8011
139	E	A	0.0000
140	R	A	-0.4207
141	V	A	0.0000
142	S	A	-1.2730
143	S	A	-1.6733
144	S	A	-1.6361
145	D	A	-2.3101
146	V	A	-1.8875
147	E	A	-2.7745
148	N	A	-2.5042
149	S	A	-1.5205
150	K	A	0.0000
151	P	A	-1.3558
152	D	A	-2.0893
153	P	A	-2.0642
154	D	A	-1.9814
155	L	A	0.0000
156	V	A	0.0000
157	Q	A	-2.0355
158	A	A	-1.5514
159	G	A	0.0000
160	L	A	0.0000
161	R	A	-2.2130
162	T	A	-0.7741
163	L	A	-0.5130
164	G	A	-0.9818
165	L	A	-0.9092
166	P	A	-1.2046
167	A	A	-0.9980
168	E	A	-1.4354
169	A	A	0.0000
170	T	A	0.0000
171	L	A	0.0000
172	M	A	0.0000
173	V	A	0.0000
174	G	A	0.0000
175	D	A	0.0000
176	T	A	0.0000
177	P	A	-0.4322
178	Y	A	-0.2842
179	D	A	0.0000
180	A	A	0.0000
181	E	A	-2.6009
182	A	A	0.0000
183	A	A	0.0000
184	R	A	-3.4340
185	K	A	-2.8132
186	A	A	-2.0235
187	G	A	-1.8410
188	V	A	0.0000
189	P	A	-1.3928
190	C	A	0.0000
191	V	A	0.0000
192	L	A	0.0000
193	L	A	0.0000
194	R	A	-1.2733
195	C	A	-0.9657
196	G	A	-0.8893
197	G	A	-1.0271
198	H	A	-0.6332
199	P	A	-0.0840
200	G	A	-0.0060
201	V	A	0.9120
202	E	A	-1.0558
203	E	A	-2.3821
204	H	A	-1.9608
205	D	A	-2.3557
206	P	A	-0.5133
207	V	A	0.0516
208	Y	A	-0.4106
209	D	A	-1.9236
210	H	A	-1.4048
211	P	A	0.0000
212	Q	A	-1.4978
213	A	A	-1.2283
214	L	A	0.0000
215	L	A	-1.4375
216	E	A	-2.3412
217	A	A	-1.7559
218	L	A	0.0000
219	D	A	-2.7544
220	Q	A	-2.2774
221	A	A	-1.1340
222	F	A	-0.2855
223	P	A	-0.3771
224	V	A	0.4676
225	E	A	-1.1267