| Chain sequence(s) |
A: MQDPYVKEAENLKKYFNAGHSDVADNGALFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTA B: MQDPYVKEAENLKKYFNAGHSDVADNGALFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKT |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 0 | M | A | 0.0540 | |
| 1 | Q | A | -1.6000 | |
| 2 | D | A | -2.0596 | |
| 3 | P | A | -1.4323 | |
| 4 | Y | A | 0.0000 | |
| 5 | V | A | -1.5168 | |
| 6 | K | A | -2.1742 | |
| 7 | E | A | 0.0000 | |
| 8 | A | A | 0.0000 | |
| 9 | E | A | -2.2123 | |
| 10 | N | A | -1.9429 | |
| 11 | L | A | 0.0000 | |
| 12 | K | A | -2.2740 | |
| 13 | K | A | -2.6005 | |
| 14 | Y | A | -0.7789 | |
| 15 | F | A | -1.1100 | |
| 16 | N | A | -2.1447 | |
| 17 | A | A | 0.0000 | |
| 18 | G | A | -2.1327 | |
| 19 | H | A | -2.1077 | |
| 20 | S | A | -1.6189 | |
| 21 | D | A | -2.2259 | |
| 22 | V | A | 0.0000 | |
| 23 | A | A | -1.8579 | |
| 24 | D | A | -2.8423 | |
| 25 | N | A | -2.4949 | |
| 26 | G | A | -1.5483 | |
| 27 | A | A | 0.0000 | |
| 28 | L | A | 0.0000 | |
| 29 | F | A | 0.0000 | |
| 30 | L | A | -0.7067 | |
| 31 | G | A | -0.9261 | |
| 32 | I | A | 0.0000 | |
| 33 | L | A | 0.0000 | |
| 34 | K | A | -2.5294 | |
| 35 | N | A | -2.3182 | |
| 36 | W | A | 0.0000 | |
| 37 | K | A | -3.8642 | |
| 38 | E | A | -3.7707 | |
| 39 | E | A | -3.4922 | |
| 40 | S | A | -2.2818 | |
| 41 | D | A | -1.9174 | |
| 42 | R | A | -2.4473 | |
| 43 | K | A | 0.0000 | |
| 44 | I | A | 0.0000 | |
| 45 | M | A | 0.0000 | |
| 46 | Q | A | 0.0000 | |
| 47 | S | A | 0.0000 | |
| 48 | Q | A | 0.0000 | |
| 49 | I | A | 0.0000 | |
| 50 | V | A | 0.0000 | |
| 51 | S | A | -0.6345 | |
| 52 | F | A | 0.0000 | |
| 53 | Y | A | 0.0000 | |
| 54 | F | A | -1.3394 | |
| 55 | K | A | -2.2478 | |
| 56 | L | A | 0.0000 | |
| 57 | F | A | 0.0000 | |
| 58 | K | A | -3.3292 | |
| 59 | N | A | -2.9860 | |
| 60 | F | A | -2.6121 | |
| 61 | K | A | -3.2876 | |
| 62 | D | A | -3.3344 | |
| 63 | D | A | -2.7222 | |
| 64 | Q | A | -2.5860 | |
| 65 | S | A | -1.5223 | |
| 66 | I | A | 0.0000 | |
| 67 | Q | A | -2.4900 | |
| 68 | K | A | -2.6405 | |
| 69 | S | A | 0.0000 | |
| 70 | V | A | 0.0000 | |
| 71 | E | A | -3.2215 | |
| 72 | T | A | -2.3551 | |
| 73 | I | A | 0.0000 | |
| 74 | K | A | -2.1865 | |
| 75 | E | A | -2.3627 | |
| 76 | D | A | -1.4547 | |
| 77 | M | A | 0.0000 | |
| 78 | N | A | -1.1844 | |
| 79 | V | A | -0.0627 | |
| 80 | K | A | -0.6642 | |
| 81 | F | A | 0.0000 | |
| 82 | F | A | 0.0000 | |
| 83 | N | A | -1.4601 | |
| 84 | S | A | -1.5336 | |
| 85 | N | A | -2.5111 | |
| 86 | K | A | -3.3151 | |
| 87 | K | A | -3.4174 | |
| 88 | K | A | 0.0000 | |
| 89 | R | A | -2.9485 | |
| 90 | D | A | -3.3889 | |
| 91 | D | A | 0.0000 | |
| 92 | F | A | 0.0000 | |
| 93 | E | A | -2.9640 | |
| 94 | K | A | -2.8978 | |
| 95 | L | A | 0.0000 | |
| 96 | T | A | -1.7971 | |
| 97 | N | A | -1.9930 | |
| 98 | Y | A | -1.0028 | |
| 99 | S | A | -0.5089 | |
| 100 | V | A | -0.5251 | |
| 101 | T | A | -0.4310 | |
| 102 | D | A | -0.5730 | |
| 103 | L | A | 0.4217 | |
| 104 | N | A | -1.0067 | |
| 105 | V | A | -0.4052 | |
| 106 | Q | A | 0.0000 | |
| 107 | R | A | -1.2928 | |
| 108 | K | A | -1.3512 | |
| 109 | A | A | 0.0000 | |
| 110 | I | A | 0.0000 | |
| 111 | H | A | -1.4614 | |
| 112 | E | A | 0.0000 | |
| 113 | L | A | 0.0000 | |
| 114 | I | A | -0.8709 | |
| 115 | Q | A | -1.2996 | |
| 116 | V | A | 0.0000 | |
| 117 | M | A | 0.0000 | |
| 118 | A | A | -1.1129 | |
| 119 | E | A | -1.5088 | |
| 120 | L | A | 0.0000 | |
| 121 | S | A | -0.6804 | |
| 122 | P | A | -0.8079 | |
| 123 | A | A | -1.1937 | |
| 124 | A | A | -1.3059 | |
| 125 | K | A | -1.6946 | |
| 126 | T | A | -0.8800 | |
| 0 | M | B | -0.0139 | |
| 1 | Q | B | -1.9076 | |
| 2 | D | B | -2.5178 | |
| 3 | P | B | -1.7276 | |
| 4 | Y | B | 0.0000 | |
| 5 | V | B | -1.9274 | |
| 6 | K | B | -2.6548 | |
| 7 | E | B | 0.0000 | |
| 8 | A | B | 0.0000 | |
| 9 | E | B | -2.2864 | |
| 10 | N | B | -1.8719 | |
| 11 | L | B | 0.0000 | |
| 12 | K | B | 0.0000 | |
| 13 | K | B | -2.4657 | |
| 14 | Y | B | -0.6962 | |
| 15 | F | B | 0.0000 | |
| 16 | N | B | -2.3129 | |
| 17 | A | B | 0.0000 | |
| 18 | G | B | -2.1561 | |
| 19 | H | B | -2.2645 | |
| 20 | S | B | -1.6900 | |
| 21 | D | B | -2.6374 | |
| 22 | V | B | 0.0000 | |
| 23 | A | B | -1.9975 | |
| 24 | D | B | -2.9543 | |
| 25 | N | B | -2.5288 | |
| 26 | G | B | -1.5217 | |
| 27 | A | B | -0.7841 | |
| 28 | L | B | 0.0000 | |
| 29 | F | B | 0.0000 | |
| 30 | L | B | -0.7645 | |
| 31 | G | B | -0.9131 | |
| 32 | I | B | 0.0000 | |
| 33 | L | B | 0.0000 | |
| 34 | K | B | -2.3761 | |
| 35 | N | B | -2.3116 | |
| 36 | W | B | 0.0000 | |
| 37 | K | B | -3.2200 | |
| 38 | E | B | -2.9574 | |
| 39 | E | B | -2.0798 | |
| 40 | S | B | -1.8473 | |
| 41 | D | B | -1.5025 | |
| 42 | R | B | 0.0000 | |
| 43 | K | B | 0.0000 | |
| 44 | I | B | 0.0000 | |
| 45 | M | B | 0.0000 | |
| 46 | Q | B | 0.0000 | |
| 47 | S | B | 0.0000 | |
| 48 | Q | B | 0.0000 | |
| 49 | I | B | 0.0000 | |
| 50 | V | B | 0.0000 | |
| 51 | S | B | -0.5456 | |
| 52 | F | B | 0.0000 | |
| 53 | Y | B | 0.0000 | |
| 54 | F | B | -1.1566 | |
| 55 | K | B | -2.0336 | |
| 56 | L | B | 0.0000 | |
| 57 | F | B | 0.0000 | |
| 58 | K | B | -3.3316 | |
| 59 | N | B | -2.7916 | |
| 60 | F | B | -2.6891 | |
| 61 | K | B | -3.9037 | |
| 62 | D | B | -3.5086 | |
| 63 | D | B | -2.7635 | |
| 64 | Q | B | -2.6011 | |
| 65 | S | B | -1.5070 | |
| 66 | I | B | 0.0000 | |
| 67 | Q | B | -2.6916 | |
| 68 | K | B | -2.7072 | |
| 69 | S | B | 0.0000 | |
| 70 | V | B | 0.0000 | |
| 71 | E | B | -3.3994 | |
| 72 | T | B | -2.4846 | |
| 73 | I | B | 0.0000 | |
| 74 | K | B | -2.3281 | |
| 75 | E | B | -2.4444 | |
| 76 | D | B | -1.5523 | |
| 77 | M | B | 0.0000 | |
| 78 | N | B | -1.2270 | |
| 79 | V | B | -0.0664 | |
| 80 | K | B | -0.6540 | |
| 81 | F | B | 0.0000 | |
| 82 | F | B | 0.0000 | |
| 83 | N | B | -1.4822 | |
| 84 | S | B | -1.5629 | |
| 85 | N | B | -2.6031 | |
| 86 | K | B | -3.4045 | |
| 87 | K | B | -3.5507 | |
| 88 | K | B | 0.0000 | |
| 89 | R | B | -2.8909 | |
| 90 | D | B | -3.2545 | |
| 91 | D | B | 0.0000 | |
| 92 | F | B | 0.0000 | |
| 93 | E | B | -2.6355 | |
| 94 | K | B | -2.5543 | |
| 95 | L | B | 0.0000 | |
| 96 | T | B | -1.6026 | |
| 97 | N | B | -1.8335 | |
| 98 | Y | B | -0.8814 | |
| 99 | S | B | -0.4706 | |
| 100 | V | B | -0.5675 | |
| 101 | T | B | -0.4641 | |
| 102 | D | B | -0.5301 | |
| 103 | L | B | 0.4460 | |
| 104 | N | B | -0.9289 | |
| 105 | V | B | -0.4322 | |
| 106 | Q | B | -0.3625 | |
| 107 | R | B | -1.2752 | |
| 108 | K | B | -1.3309 | |
| 109 | A | B | 0.0000 | |
| 110 | I | B | 0.0000 | |
| 111 | H | B | -1.4209 | |
| 112 | E | B | 0.0000 | |
| 113 | L | B | 0.0000 | |
| 114 | I | B | -0.7230 | |
| 115 | Q | B | -1.0823 | |
| 116 | V | B | 0.0000 | |
| 117 | M | B | 0.0000 | |
| 118 | A | B | -1.0071 | |
| 119 | E | B | -1.8450 | |
| 120 | L | B | 0.0000 | |
| 121 | S | B | -0.8968 | |
| 122 | P | B | -1.6659 | |
| 123 | A | B | -1.4734 | |
| 124 | A | B | -0.8173 | |
| 125 | K | B | -1.7182 | |
| 126 | T | B | -1.9154 | |
| 27 | A | A | 0.0000 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine