Project name: 3ade_a_Valen

Chain sequence(s)	A: GRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0318
• Maximal score value: 1.771
• Average score: -0.6125
• Total score value: -177.0073

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
325	G	A	-1.6520
326	R	A	-2.5050
327	L	A	0.0000
328	I	A	0.0000
329	Y	A	0.0000
330	T	A	0.0000
331	A	A	0.0000
332	G	A	0.0000
333	G	A	0.0000
334	Y	A	-0.1096
335	F	A	-0.4056
336	R	A	-1.8348
337	Q	A	-1.5197
338	S	A	0.0000
339	L	A	0.0000
340	S	A	-0.3577
341	Y	A	-0.5607
342	L	A	0.0000
343	E	A	0.0000
344	A	A	0.0000
345	Y	A	0.0000
346	N	A	-1.2621
347	P	A	-1.0364
348	S	A	-1.3064
349	N	A	-1.5726
350	G	A	-1.1109
351	S	A	-0.6930
352	W	A	-0.4448
353	L	A	-0.3876
354	R	A	-1.5725
355	L	A	-1.1055
356	A	A	-1.4939
357	D	A	-1.7804
358	L	A	0.0000
359	Q	A	-1.1242
360	V	A	0.2877
361	P	A	-0.1623
362	R	A	0.0000
363	S	A	-0.5090
364	G	A	-0.7981
365	L	A	0.0000
366	A	A	-0.1758
367	G	A	0.1321
368	C	A	0.0000
369	V	A	0.5455
370	V	A	-0.0480
371	G	A	-0.3024
372	G	A	0.1238
373	L	A	0.4046
374	L	A	0.0000
375	Y	A	0.0000
376	A	A	0.0000
377	V	A	0.0000
378	G	A	0.0000
379	G	A	0.0000
380	R	A	-1.1727
381	N	A	-1.2138
382	N	A	-1.9232
383	S	A	-1.9268
384	P	A	-1.8675
385	D	A	-2.3916
386	G	A	-2.0436
387	N	A	-2.3168
388	T	A	-1.4947
389	D	A	-1.2031
390	S	A	-0.5346
391	S	A	-0.2241
392	A	A	-0.0258
393	L	A	0.0000
394	D	A	0.0000
395	C	A	-0.1152
396	Y	A	0.0000
397	N	A	-0.2407
398	P	A	0.0000
399	M	A	0.6764
400	T	A	-0.0373
401	N	A	-0.7737
402	Q	A	-1.6139
403	W	A	-1.1885
404	S	A	-0.7418
405	P	A	-0.4011
406	C	A	-0.4752
407	A	A	-1.1073
408	S	A	-0.5840
409	M	A	0.0000
410	S	A	-0.0420
411	V	A	0.0547
412	P	A	-0.3090
413	R	A	0.0000
414	N	A	0.0000
415	R	A	-1.3981
416	I	A	0.0000
417	G	A	0.0000
418	V	A	0.2526
419	G	A	0.0000
420	V	A	-0.1907
421	I	A	0.0000
422	D	A	-2.1918
423	G	A	-1.3922
424	H	A	-1.2457
425	I	A	0.0000
426	Y	A	0.0000
427	A	A	0.0000
428	V	A	0.0000
429	G	A	0.0000
430	G	A	0.0000
431	S	A	0.0000
432	H	A	-0.0131
433	G	A	0.0785
434	C	A	1.2880
435	I	A	1.7710
436	H	A	0.2298
437	H	A	-0.1287
438	S	A	-0.2557
439	S	A	0.0213
440	V	A	0.0000
441	E	A	0.0000
442	R	A	-0.8697
443	Y	A	0.0000
444	E	A	-3.1021
445	P	A	-2.7801
446	E	A	-3.6206
447	R	A	-4.0318
448	D	A	-3.6593
449	E	A	-3.6747
450	W	A	-1.8389
451	H	A	-1.0179
452	L	A	0.5939
453	V	A	0.0000
454	A	A	-0.5780
455	P	A	-0.2577
456	M	A	0.0000
457	L	A	0.7672
458	T	A	0.1732
459	R	A	-0.7704
460	R	A	0.0000
461	I	A	-0.3654
462	G	A	-0.4266
463	V	A	0.0000
464	G	A	0.0000
465	V	A	0.0000
466	A	A	0.0000
467	V	A	-0.0827
468	L	A	-0.9498
469	N	A	-2.0713
470	R	A	-2.4349
471	L	A	-0.9379
472	L	A	0.0000
473	Y	A	0.0000
474	A	A	0.0000
475	V	A	0.0000
476	G	A	0.0000
477	G	A	0.0000
478	F	A	-0.6332
479	D	A	-0.8552
480	G	A	-0.4271
481	T	A	-0.9163
482	N	A	-1.6623
483	R	A	-1.1815
484	L	A	-0.5427
485	N	A	-0.6847
486	S	A	-0.2190
487	A	A	0.0000
488	E	A	0.0000
489	C	A	0.0000
490	Y	A	0.0000
491	Y	A	-2.1444
492	P	A	-2.3735
493	E	A	-3.1679
494	R	A	-3.6682
495	N	A	-3.1037
496	E	A	-3.3277
497	W	A	0.0000
498	R	A	-1.5684
499	M	A	0.0726
500	I	A	-0.2508
501	T	A	-0.4720
502	P	A	-0.5302
503	M	A	0.0000
504	N	A	-1.0429
505	T	A	-0.3939
506	I	A	-0.4037
507	R	A	0.0000
508	S	A	0.0000
509	G	A	-0.2785
510	A	A	0.0483
511	G	A	0.0000
512	V	A	0.0000
513	C	A	0.0000
514	V	A	-0.0876
515	L	A	0.0000
516	H	A	-1.4491
517	N	A	-1.6605
518	C	A	0.0000
519	I	A	0.0000
520	Y	A	0.0000
521	A	A	0.0000
522	A	A	0.0000
523	G	A	0.0000
524	G	A	0.0000
525	Y	A	-0.8864
526	D	A	-1.4733
527	G	A	-1.7893
528	Q	A	-2.2283
529	D	A	-2.5726
530	Q	A	-1.6110
531	L	A	-0.9256
532	N	A	-1.2153
533	S	A	-0.1838
534	V	A	0.0000
535	E	A	0.0000
536	R	A	-0.2218
537	Y	A	0.0000
538	D	A	-1.7631
539	V	A	-1.6725
540	E	A	-2.4588
541	T	A	-1.7714
542	E	A	-2.2531
543	T	A	-1.4230
544	W	A	0.0000
545	T	A	0.3761
546	F	A	1.3396
547	V	A	0.6158
548	A	A	-0.2143
549	P	A	-0.6024
550	M	A	0.0000
551	R	A	-2.4969
552	H	A	-1.6931
553	H	A	-1.4832
554	R	A	0.0000
555	S	A	0.0000
556	A	A	-0.0580
557	L	A	0.0000
558	G	A	0.0000
559	I	A	0.3637
560	T	A	0.3429
561	V	A	0.0752
562	H	A	0.0000
563	Q	A	-1.6515
564	G	A	-1.4918
565	K	A	-1.3450
566	I	A	0.0000
567	Y	A	0.0000
568	V	A	0.0000
569	L	A	0.0000
570	G	A	0.0000
571	G	A	0.0000
572	Y	A	0.0518
573	D	A	-1.0639
574	G	A	-1.0904
575	H	A	-1.0914
576	T	A	-0.3892
577	F	A	0.0552
578	L	A	-0.2805
579	D	A	-0.7591
580	S	A	0.0000
581	V	A	0.0000
582	E	A	0.0000
583	C	A	0.0000
584	Y	A	0.0000
585	D	A	-1.7500
586	P	A	-1.8102
587	D	A	-2.4404
588	S	A	-1.6572
589	D	A	-1.6913
590	T	A	-1.1812
591	W	A	-1.1542
592	S	A	-1.2417
593	E	A	-2.1635
594	V	A	-0.6357
595	T	A	-1.2011
596	R	A	-2.1237
597	M	A	0.0000
598	T	A	-0.7502
599	S	A	-0.4327
600	G	A	0.0000
601	R	A	0.0000
602	S	A	0.0000
603	G	A	-0.0983
604	V	A	0.0000
605	G	A	0.0000
606	V	A	0.3336
607	A	A	0.0000
608	V	A	-0.1617
609	T	A	0.0000
610	M	A	-1.0439
611	E	A	-1.8643
612	P	A	0.0000
613	C	A	0.6087