Project name: H3807-1

Chain sequence(s)	H: EVQLVQSGAEVKKPGASVKVSCKASGYTFTNYWLGWIKQAPGQGLEWIGDIYPGGDYIVYNEKFKGKATLTADTSISTAYMELSRLRSDDTAVYYCARPNLPKDHWGQGTTVTVSS; L: DIVMTQSPLSLPVTPGEPASISCRSSKSLLHSQGITYLYWYLQKPGQSPQLLIYQVSNLASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCAQYLELPWTFGGGTKVEIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5595
• Maximal score value: 1.0767
• Average score: -0.694
• Total score value: -158.2238

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.8291
2	I	L	0.0000
3	V	L	0.2460
4	M	L	0.0000
5	T	L	-0.6337
6	Q	L	-0.3770
7	S	L	-0.2643
8	P	L	0.2743
9	L	L	1.0463
10	S	L	-0.1277
11	L	L	-0.3780
12	P	L	-1.0681
13	V	L	0.0000
14	T	L	-1.5422
15	P	L	-1.7906
16	G	L	-2.0143
17	E	L	-2.3710
18	P	L	-2.1809
19	A	L	0.0000
20	S	L	-0.6247
21	I	L	0.0000
22	S	L	-1.1393
23	C	L	0.0000
24	R	L	-2.7110
25	S	L	-1.5977
26	S	L	-1.4038
27	K	L	-2.1045
28	S	L	-1.2274
29	L	L	0.0000
30	L	L	0.5158
30A	H	L	-0.3634
30B	S	L	-0.8277
30C	Q	L	-1.3647
30D	G	L	-0.7437
30E	I	L	0.0633
31	T	L	0.2902
32	Y	L	0.3778
33	L	L	0.0000
34	Y	L	0.0000
35	W	L	0.0000
36	Y	L	0.0000
37	L	L	0.0000
38	Q	L	-0.9048
39	K	L	-1.4566
40	P	L	-1.0222
41	G	L	-1.3211
42	Q	L	-1.9803
43	S	L	-1.3420
44	P	L	0.0000
45	Q	L	-0.9676
46	L	L	-0.4292
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	0.0872
50	Q	L	0.2007
51	V	L	0.0000
52	S	L	-0.4531
53	N	L	-0.4469
54	L	L	-0.2983
55	A	L	-0.5272
56	S	L	-0.5395
57	G	L	-0.6285
58	V	L	-0.5628
59	P	L	-1.1034
60	D	L	-2.0870
61	R	L	-2.0927
62	F	L	0.0000
63	S	L	-1.0379
64	G	L	0.0000
65	S	L	-0.8443
66	G	L	-1.2877
67	S	L	-0.7617
68	G	L	-0.9606
69	T	L	-1.9401
70	D	L	-2.9325
71	F	L	0.0000
72	T	L	-1.1446
73	L	L	0.0000
74	K	L	-1.5422
75	I	L	0.0000
76	S	L	-2.2487
77	R	L	-3.1022
78	V	L	0.0000
79	E	L	-2.6133
80	A	L	-1.5277
81	E	L	-2.3829
82	D	L	0.0000
83	V	L	-1.0916
84	G	L	0.0000
85	V	L	-0.4324
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	A	L	0.0000
90	Q	L	0.0000
91	Y	L	0.2504
92	L	L	-0.0769
93	E	L	-1.1227
94	L	L	0.2844
95	P	L	-0.3460
96	W	L	0.2331
97	T	L	0.0792
98	F	L	0.2528
99	G	L	0.0000
100	G	L	-0.4744
101	G	L	0.0000
102	T	L	0.0000
103	K	L	-1.1345
104	V	L	0.0000
105	E	L	-1.8634
106	I	L	-0.5335
107	K	L	-1.5314
1	E	H	-2.1038
2	V	H	-1.5208
3	Q	H	-1.8891
4	L	H	0.0000
5	V	H	-0.1356
6	Q	H	0.0000
7	S	H	-0.8749
8	G	H	-0.9619
9	A	H	-0.7406
10	E	H	-1.3526
11	V	H	0.1932
12	K	H	-1.3383
13	K	H	-2.3764
14	P	H	-2.4565
15	G	H	-2.2895
16	A	H	-1.7860
17	S	H	-1.8500
18	V	H	0.0000
19	K	H	-2.2233
20	V	H	0.0000
21	S	H	-0.7247
22	C	H	0.0000
23	K	H	-1.0478
24	A	H	0.0000
25	S	H	-0.8612
26	G	H	-1.1023
27	Y	H	-0.5520
28	T	H	-0.3898
29	F	H	0.0000
30	T	H	-0.9600
31	N	H	-1.3117
32	Y	H	-0.4209
33	W	H	-0.0841
34	L	H	0.0000
35	G	H	0.0000
36	W	H	0.0000
37	I	H	0.0000
38	K	H	-0.3143
39	Q	H	0.0000
40	A	H	-0.9370
41	P	H	-0.8462
42	G	H	-1.2430
43	Q	H	-1.6646
44	G	H	-1.0180
45	L	H	0.0000
46	E	H	-0.7513
47	W	H	0.0000
48	I	H	0.0000
49	G	H	0.0000
50	D	H	0.0000
51	I	H	0.0000
52	Y	H	-0.0389
52A	P	H	0.0000
53	G	H	-1.0402
54	G	H	-0.9796
55	D	H	-1.0869
56	Y	H	0.8422
57	I	H	1.0767
58	V	H	0.8148
59	Y	H	-0.6263
60	N	H	0.0000
61	E	H	-3.3108
62	K	H	-3.2027
63	F	H	0.0000
64	K	H	-3.1232
65	G	H	-2.1310
66	K	H	-2.0454
67	A	H	0.0000
68	T	H	-0.8568
69	L	H	0.0000
70	T	H	-0.3115
71	A	H	-0.5818
72	D	H	-0.7552
73	T	H	-0.3274
74	S	H	0.3287
75	I	H	1.0691
76	S	H	0.0640
77	T	H	0.0000
78	A	H	0.0000
79	Y	H	-0.7370
80	M	H	0.0000
81	E	H	-1.6039
82	L	H	0.0000
82A	S	H	-1.9295
82B	R	H	-2.8590
82C	L	H	0.0000
83	R	H	-3.5595
84	S	H	-2.4632
85	D	H	-2.6187
86	D	H	-1.9614
87	T	H	-0.9665
88	A	H	0.0000
89	V	H	-0.0016
90	Y	H	0.0000
91	Y	H	0.0000
92	C	H	0.0000
93	A	H	0.0000
94	R	H	0.0000
95	P	H	0.0000
96	N	H	-1.0939
97	L	H	0.0224
98	P	H	-0.4089
99	K	H	0.0000
101	D	H	-1.8952
102	H	H	-1.6119
103	W	H	0.0000
104	G	H	0.0000
105	Q	H	-1.3843
106	G	H	-0.6906
107	T	H	0.0000
108	T	H	-0.3115
109	V	H	0.0000
110	T	H	-0.7206
111	V	H	0.0000
112	S	H	-0.9347
113	S	H	-0.7574