Chain sequence(s) |
A: EGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFM E: IPF |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
2 | E | A | -2.2583 | |
3 | G | A | -1.4910 | |
4 | W | A | -0.8778 | |
5 | Q | A | 0.0000 | |
6 | R | A | -1.1198 | |
7 | A | A | 0.0000 | |
8 | F | A | 0.0000 | |
9 | V | A | 0.0000 | |
10 | L | A | 0.0000 | |
11 | H | A | -1.1367 | |
12 | S | A | -1.4516 | |
13 | R | A | -1.9270 | |
14 | P | A | -1.1618 | |
15 | W | A | -0.3821 | |
16 | S | A | -1.1763 | |
17 | E | A | -2.1014 | |
18 | T | A | -1.8072 | |
19 | S | A | 0.0000 | |
20 | L | A | 0.0000 | |
21 | M | A | 0.0000 | |
22 | L | A | 0.0000 | |
23 | D | A | 0.0000 | |
24 | V | A | 0.0000 | |
25 | F | A | 0.0000 | |
26 | T | A | 0.0000 | |
27 | E | A | -1.3589 | |
28 | E | A | -2.6901 | |
29 | S | A | -2.1975 | |
30 | G | A | 0.0000 | |
31 | R | A | 0.0000 | |
32 | V | A | 0.0000 | |
33 | R | A | -0.9751 | |
34 | L | A | 0.0000 | |
35 | V | A | -0.4920 | |
36 | A | A | 0.0000 | |
37 | K | A | -2.1475 | |
38 | G | A | -2.1265 | |
39 | A | A | 0.0000 | |
40 | R | A | -2.6295 | |
41 | S | A | -2.6528 | |
42 | K | A | -3.0290 | |
43 | R | A | -3.0044 | |
44 | S | A | -2.1412 | |
45 | T | A | -1.4293 | |
46 | L | A | -1.5749 | |
47 | K | A | -2.0473 | |
48 | G | A | -0.7561 | |
49 | A | A | -0.3497 | |
50 | L | A | 0.0000 | |
51 | Q | A | -0.5397 | |
52 | P | A | -0.1914 | |
53 | F | A | 0.0000 | |
54 | T | A | 0.0000 | |
55 | P | A | 0.0449 | |
56 | L | A | 0.0000 | |
57 | L | A | -0.2995 | |
58 | L | A | 0.0000 | |
59 | R | A | -1.6221 | |
60 | F | A | 0.0000 | |
61 | G | A | -1.6218 | |
62 | G | A | -1.6766 | |
63 | R | A | -2.5401 | |
64 | G | A | -2.0703 | |
65 | E | A | -2.4040 | |
66 | V | A | -0.7882 | |
67 | K | A | 0.0000 | |
68 | T | A | -1.2384 | |
69 | L | A | -1.2443 | |
70 | R | A | -2.1239 | |
71 | S | A | -1.2485 | |
72 | A | A | -1.1768 | |
73 | E | A | -1.2039 | |
74 | A | A | 0.2914 | |
75 | V | A | 1.7458 | |
76 | S | A | 1.4440 | |
77 | L | A | 1.9117 | |
78 | A | A | 1.5975 | |
79 | L | A | 1.7737 | |
80 | P | A | 0.6910 | |
81 | L | A | 0.0000 | |
82 | S | A | 0.2339 | |
83 | G | A | 0.5213 | |
84 | I | A | 1.1104 | |
85 | T | A | 0.0000 | |
86 | L | A | 0.8125 | |
87 | Y | A | 0.8856 | |
88 | S | A | 0.0000 | |
89 | G | A | 0.0000 | |
90 | L | A | 0.3324 | |
91 | Y | A | 0.0000 | |
92 | I | A | 0.0000 | |
93 | N | A | 0.0000 | |
94 | E | A | 0.0000 | |
95 | L | A | 0.0000 | |
96 | L | A | 0.0000 | |
97 | S | A | -0.5971 | |
98 | R | A | -1.0357 | |
99 | V | A | 0.0000 | |
100 | L | A | 0.0000 | |
101 | E | A | -2.2778 | |
102 | Y | A | -1.9519 | |
103 | E | A | -3.0007 | |
104 | T | A | -2.2782 | |
105 | R | A | -3.0165 | |
106 | F | A | -1.7712 | |
107 | S | A | -1.3557 | |
108 | E | A | -1.4910 | |
109 | L | A | 0.0000 | |
110 | F | A | 0.0000 | |
111 | F | A | 0.6472 | |
112 | D | A | -0.5180 | |
113 | Y | A | 0.0000 | |
114 | L | A | -0.2604 | |
115 | H | A | -1.1592 | |
116 | C | A | 0.0000 | |
117 | I | A | 0.0000 | |
118 | Q | A | -1.5931 | |
119 | S | A | -0.9208 | |
120 | L | A | 0.0000 | |
121 | A | A | -0.3931 | |
122 | G | A | -0.6016 | |
123 | V | A | -0.0473 | |
124 | T | A | -0.1075 | |
125 | G | A | -0.3935 | |
126 | T | A | -0.2895 | |
127 | P | A | 0.0000 | |
128 | E | A | -0.9629 | |
129 | P | A | -1.2111 | |
130 | A | A | -1.1604 | |
131 | L | A | 0.0000 | |
132 | R | A | 0.0000 | |
133 | R | A | -2.0920 | |
134 | F | A | 0.0000 | |
135 | E | A | 0.0000 | |
136 | L | A | 0.0000 | |
137 | A | A | -0.9714 | |
138 | L | A | 0.0000 | |
139 | L | A | 0.0000 | |
140 | G | A | -0.7215 | |
141 | H | A | -0.8777 | |
142 | L | A | -0.3582 | |
143 | G | A | -0.6033 | |
144 | Y | A | -0.8367 | |
145 | G | A | -1.0538 | |
146 | V | A | -1.8180 | |
147 | N | A | -1.7970 | |
148 | F | A | 0.0000 | |
149 | T | A | -1.9060 | |
150 | H | A | -1.8694 | |
151 | C | A | 0.0000 | |
152 | A | A | -1.5087 | |
153 | G | A | -1.2340 | |
154 | S | A | -1.2851 | |
155 | G | A | -1.7428 | |
156 | E | A | -2.5525 | |
157 | P | A | -1.7850 | |
158 | V | A | -1.6705 | |
159 | D | A | -2.0792 | |
160 | D | A | -1.8277 | |
161 | T | A | -0.7695 | |
162 | M | A | 0.0176 | |
163 | T | A | 0.7786 | |
164 | Y | A | 0.0000 | |
165 | R | A | -0.7570 | |
166 | Y | A | 0.0000 | |
167 | R | A | -3.5919 | |
168 | E | A | -4.0538 | |
169 | E | A | -3.9145 | |
170 | K | A | -3.9002 | |
171 | G | A | -2.6763 | |
172 | F | A | 0.0000 | |
173 | I | A | -0.4657 | |
174 | A | A | 0.3417 | |
175 | S | A | 1.7296 | |
176 | V | A | 2.9917 | |
177 | V | A | 2.7338 | |
178 | I | A | 2.3063 | |
179 | D | A | -0.2619 | |
180 | N | A | -1.6578 | |
181 | K | A | -1.8113 | |
182 | T | A | 0.0000 | |
183 | F | A | 0.0000 | |
184 | T | A | -1.1925 | |
185 | G | A | 0.0000 | |
186 | R | A | -2.9256 | |
187 | Q | A | 0.0000 | |
188 | L | A | 0.0000 | |
189 | K | A | -2.9462 | |
190 | A | A | 0.0000 | |
191 | L | A | 0.0000 | |
192 | N | A | -2.5847 | |
193 | A | A | -2.0412 | |
194 | R | A | -2.5843 | |
195 | E | A | -2.9676 | |
196 | F | A | 0.0000 | |
197 | P | A | -1.5961 | |
198 | D | A | -2.2536 | |
199 | A | A | -1.8858 | |
200 | D | A | -2.9262 | |
201 | T | A | 0.0000 | |
202 | L | A | -2.1978 | |
203 | R | A | -2.5578 | |
204 | A | A | 0.0000 | |
205 | A | A | 0.0000 | |
206 | K | A | -1.5757 | |
207 | R | A | -1.8170 | |
208 | F | A | 0.0000 | |
209 | T | A | 0.0000 | |
210 | R | A | -2.0101 | |
211 | M | A | -1.7674 | |
212 | A | A | 0.0000 | |
213 | L | A | 0.0000 | |
214 | K | A | -2.3435 | |
215 | P | A | -1.3737 | |
216 | Y | A | -0.4293 | |
217 | L | A | -1.2249 | |
218 | G | A | -1.5363 | |
219 | G | A | -1.8146 | |
220 | K | A | -2.5985 | |
221 | P | A | -2.1518 | |
222 | L | A | 0.0000 | |
223 | K | A | -2.8707 | |
224 | S | A | 0.0000 | |
225 | R | A | -2.4229 | |
226 | E | A | -3.2380 | |
227 | L | A | -1.4761 | |
228 | F | A | -0.7477 | |
229 | R | A | -2.2718 | |
230 | Q | A | -1.2687 | |
231 | F | A | 1.2548 | |
232 | M | A | 1.2976 | |
7 | I | E | 1.8361 | |
8 | P | E | 0.9394 | |
9 | F | E | 0.3885 |