Project name: d22de8ccc0275fb

Chain sequence(s)	H: EVQLQQSGAELVKPGASVKLSCTASGFNIKDTYVHWVKQRPEQGLEWIGRIDPANGYTKYDPKFQGKATITADTSSNTAYLQLSSLTSEDTAVYYCVRPLYDYYAMDYWGQGTSVTVSS; L: DILMTQSPSSMSVSLGDTVSITCHASQGISSNIGWLQQKPGKSFKGLIYYGTNLVDGVPSRFSGSGSGADYSLTISSLESEDFADYYCVQYAQLPYTFGGGTKLEIK
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.901
• Maximal score value: 1.5255
• Average score: -0.6054
• Total score value: -136.814

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	L	-1.7651
2	I	L	0.0000
3	L	L	0.6013
4	M	L	0.1327
5	T	L	-0.2995
6	Q	L	0.0000
7	S	L	-0.6356
8	P	L	-0.5611
9	S	L	-0.7809
10	S	L	-1.1474
11	M	L	-0.7536
12	S	L	-0.7826
13	V	L	-0.3216
14	S	L	-0.3023
15	L	L	0.1613
16	G	L	-0.6844
17	D	L	-0.9462
18	T	L	-0.7054
19	V	L	0.0000
20	S	L	-0.2112
21	I	L	0.0000
22	T	L	-0.6873
23	C	L	0.0000
24	H	L	-1.4343
25	A	L	-0.9400
26	S	L	-0.9487
27	Q	L	-1.9536
28	G	L	-1.7676
29	I	L	0.0000
30	S	L	-0.8700
31	S	L	-0.4649
32	N	L	-0.2350
33	I	L	0.0000
34	G	L	0.0000
35	W	L	0.0000
36	L	L	0.0000
37	Q	L	0.0000
38	Q	L	0.0000
39	K	L	-1.9130
40	P	L	-1.6357
41	G	L	-1.5160
42	K	L	-2.5066
43	S	L	-1.6639
44	F	L	0.0000
45	K	L	-1.1461
46	G	L	0.0000
47	L	L	0.0000
48	I	L	0.0000
49	Y	L	0.6171
50	Y	L	0.8169
51	G	L	0.0000
52	T	L	-0.1341
53	N	L	-0.3073
54	L	L	-0.3085
55	V	L	0.0000
56	D	L	-1.7993
57	G	L	-1.4241
58	V	L	0.0000
59	P	L	-0.6796
60	S	L	-0.4857
61	R	L	-0.7849
62	F	L	0.0000
63	S	L	-0.4392
64	G	L	-0.2466
65	S	L	-0.7181
66	G	L	-1.3118
67	S	L	-1.3619
68	G	L	-1.7149
69	A	L	-2.0244
70	D	L	-2.6116
71	Y	L	0.0000
72	S	L	-0.7875
73	L	L	0.0000
74	T	L	-0.3114
75	I	L	0.0000
76	S	L	-0.9297
77	S	L	-0.9729
78	L	L	0.0000
79	E	L	-2.1181
80	S	L	-1.4916
81	E	L	-2.3984
82	D	L	0.0000
83	F	L	0.0000
84	A	L	0.0000
85	D	L	-1.2227
86	Y	L	0.0000
87	Y	L	0.0000
88	C	L	0.0000
89	V	L	0.0000
90	Q	L	0.0000
91	Y	L	0.0000
92	A	L	-0.7526
93	Q	L	-1.1010
94	L	L	-0.6328
95	P	L	-0.7157
96	Y	L	0.0000
97	T	L	-0.0408
98	F	L	0.0000
99	G	L	0.0000
100	G	L	-1.1687
101	G	L	-0.9569
102	T	L	0.0000
103	K	L	-2.0330
104	L	L	0.0000
105	E	L	-1.5610
106	I	L	0.0869
107	K	L	-1.1011
108	E	H	-1.9143
109	V	H	-1.1089
110	Q	H	-1.3710
111	L	H	0.0000
112	Q	H	-1.3576
113	Q	H	0.0000
114	S	H	-1.0222
115	G	H	-1.0239
116	A	H	-0.4403
117	E	H	-0.7764
118	L	H	0.6194
119	V	H	-0.3786
120	K	H	-1.6382
121	P	H	-1.3485
122	G	H	-1.0950
123	A	H	-0.7106
124	S	H	-0.9140
125	V	H	0.0000
126	K	H	-2.1316
127	L	H	0.0000
128	S	H	-0.6390
129	C	H	0.0000
130	T	H	-0.7517
131	A	H	0.0000
132	S	H	-1.1457
133	G	H	-1.2702
134	F	H	-1.5755
135	N	H	-2.3471
136	I	H	0.0000
137	K	H	-2.8581
138	D	H	-2.6852
139	T	H	-0.9422
140	Y	H	-0.0574
141	V	H	0.0000
142	H	H	0.0000
143	W	H	0.0000
144	V	H	0.0000
145	K	H	0.0000
146	Q	H	-0.7517
147	R	H	-1.6202
148	P	H	-1.6529
149	E	H	-2.9010
150	Q	H	-2.6364
151	G	H	0.0000
152	L	H	0.0000
153	E	H	-0.9007
154	W	H	0.0000
155	I	H	0.0000
156	G	H	0.0000
157	R	H	0.0000
158	I	H	0.0000
159	D	H	-1.0086
160	P	H	0.0000
161	A	H	-1.5344
162	N	H	-1.2994
163	G	H	-0.6126
164	Y	H	0.4342
165	T	H	-0.2914
166	K	H	-1.2066
167	Y	H	-1.2515
168	D	H	0.0000
169	P	H	-1.7847
170	K	H	-2.2596
171	F	H	0.0000
172	Q	H	-2.2069
173	G	H	-1.4717
174	K	H	-1.3707
175	A	H	0.0000
176	T	H	-0.9188
177	I	H	0.0000
178	T	H	-0.1084
179	A	H	-0.6301
180	D	H	-0.9687
181	T	H	-1.4740
182	S	H	-0.8643
183	S	H	-0.7566
184	N	H	-1.1664
185	T	H	0.0000
186	A	H	0.0000
187	Y	H	-0.3977
188	L	H	0.0000
189	Q	H	-1.3538
190	L	H	0.0000
191	S	H	-0.8852
192	S	H	-0.8257
193	L	H	0.0000
194	T	H	-1.2697
195	S	H	-1.4565
196	E	H	-2.3519
197	D	H	0.0000
198	T	H	-0.4566
199	A	H	0.0000
200	V	H	0.1030
201	Y	H	0.0000
202	Y	H	0.0000
203	C	H	0.0000
204	V	H	0.0000
205	R	H	0.0940
206	P	H	0.0000
207	L	H	0.6567
208	Y	H	1.4317
209	D	H	1.0442
210	Y	H	1.5255
211	Y	H	0.0000
212	A	H	0.0000
213	M	H	0.0000
214	D	H	0.0000
215	Y	H	-0.2211
216	W	H	0.0000
217	G	H	0.0000
218	Q	H	-1.8735
219	G	H	-1.0392
220	T	H	0.0000
221	S	H	-0.2571
222	V	H	0.0000
223	T	H	-0.1923
224	V	H	0.0000
225	S	H	-0.5172
226	S	H	-0.6624