Project name: 5wt9:H
Status: done
submitted: 2019-03-21 17:13:15, status changed: 2019-03-21 17:21:04
Settings
Chain sequence(s)
|
H: QVQLVESGGGVVQPGRSLRLDCKASGITFSNSGMHWVRQAPGKGLEWVAVIWYDGSKRYYADSVKGRFTISRDNSKNTLFLQMNSLRAEDTAVYYCATNDDYWGQGTLVTVSSASTKGPSVFPLAPCSTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESK
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.0741
-
Maximal score value
-
2.4372
-
Average score
-
-0.6642
-
Total score value
-
-138.1576
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
1 |
Q |
H |
-1.3167 |
|
2 |
V |
H |
-0.5099 |
|
3 |
Q |
H |
-1.3064 |
|
4 |
L |
H |
0.0000 |
|
5 |
V |
H |
-0.3204 |
|
6 |
E |
H |
0.0000 |
|
7 |
S |
H |
-0.6508 |
|
8 |
G |
H |
-0.8509 |
|
9 |
G |
H |
-0.4159 |
|
10 |
G |
H |
0.1400 |
|
11 |
V |
H |
0.4579 |
|
12 |
V |
H |
0.0000 |
|
13 |
Q |
H |
-1.4006 |
|
14 |
P |
H |
-1.8751 |
|
15 |
G |
H |
-1.9831 |
|
16 |
R |
H |
-2.6246 |
|
17 |
S |
H |
-2.0159 |
|
18 |
L |
H |
-1.3941 |
|
19 |
R |
H |
-2.0854 |
|
20 |
L |
H |
0.0000 |
|
21 |
D |
H |
-1.1337 |
|
22 |
C |
H |
0.0000 |
|
23 |
K |
H |
-1.6313 |
|
24 |
A |
H |
0.0000 |
|
25 |
S |
H |
-0.9888 |
|
26 |
G |
H |
-0.7551 |
|
27 |
I |
H |
-0.3486 |
|
28 |
T |
H |
-0.5786 |
|
29 |
F |
H |
0.0000 |
|
30 |
S |
H |
-1.3469 |
|
31 |
N |
H |
-1.4800 |
|
32 |
S |
H |
-1.4397 |
|
33 |
G |
H |
-1.1176 |
|
34 |
M |
H |
0.0000 |
|
35 |
H |
H |
-0.3450 |
|
36 |
W |
H |
0.0000 |
|
37 |
V |
H |
0.0000 |
|
38 |
R |
H |
0.0000 |
|
39 |
Q |
H |
-0.4751 |
|
40 |
A |
H |
-1.0948 |
|
41 |
P |
H |
-0.9027 |
|
42 |
G |
H |
-1.4446 |
|
43 |
K |
H |
-2.0827 |
|
44 |
G |
H |
-0.9524 |
|
45 |
L |
H |
0.5769 |
|
46 |
E |
H |
-0.1977 |
|
47 |
W |
H |
0.2536 |
|
48 |
V |
H |
0.0000 |
|
49 |
A |
H |
0.0000 |
|
50 |
V |
H |
0.0000 |
|
51 |
I |
H |
0.0000 |
|
52 |
W |
H |
-0.7857 |
|
53 |
Y |
H |
-0.7549 |
|
54 |
D |
H |
-1.9861 |
|
55 |
G |
H |
-1.4152 |
|
56 |
S |
H |
-1.3420 |
|
57 |
K |
H |
-1.5093 |
|
58 |
R |
H |
-1.0032 |
|
59 |
Y |
H |
0.0107 |
|
60 |
Y |
H |
-0.5676 |
|
61 |
A |
H |
-1.1234 |
|
62 |
D |
H |
-2.2572 |
|
63 |
S |
H |
-1.7643 |
|
64 |
V |
H |
0.0000 |
|
65 |
K |
H |
-2.4513 |
|
66 |
G |
H |
-1.8031 |
|
67 |
R |
H |
-1.4172 |
|
68 |
F |
H |
0.0000 |
|
69 |
T |
H |
-0.8275 |
|
70 |
I |
H |
0.0000 |
|
71 |
S |
H |
-0.4043 |
|
72 |
R |
H |
-1.0385 |
|
73 |
D |
H |
-1.6563 |
|
74 |
N |
H |
-2.0416 |
|
75 |
S |
H |
-1.6659 |
|
76 |
K |
H |
-2.5756 |
|
77 |
N |
H |
-1.9963 |
|
78 |
T |
H |
-1.5892 |
|
79 |
L |
H |
0.0000 |
|
80 |
F |
H |
-0.6330 |
|
81 |
L |
H |
0.0000 |
|
82 |
Q |
H |
-1.1429 |
|
83 |
M |
H |
0.0000 |
|
84 |
N |
H |
-1.9031 |
|
85 |
S |
H |
-1.6901 |
|
86 |
L |
H |
0.0000 |
|
87 |
R |
H |
-2.5397 |
|
88 |
A |
H |
-1.6854 |
|
89 |
E |
H |
-2.2678 |
|
90 |
D |
H |
0.0000 |
|
91 |
T |
H |
-0.7074 |
|
92 |
A |
H |
0.0000 |
|
93 |
V |
H |
0.3293 |
|
94 |
Y |
H |
0.0000 |
|
95 |
Y |
H |
0.2884 |
|
96 |
C |
H |
0.0000 |
|
97 |
A |
H |
0.0000 |
|
98 |
T |
H |
0.0000 |
|
99 |
N |
H |
-2.5914 |
|
100 |
D |
H |
-3.0741 |
|
101 |
D |
H |
-2.6525 |
|
102 |
Y |
H |
-0.9380 |
|
103 |
W |
H |
-0.3435 |
|
104 |
G |
H |
-0.5184 |
|
105 |
Q |
H |
-0.9968 |
|
106 |
G |
H |
-0.2951 |
|
107 |
T |
H |
-0.0331 |
|
108 |
L |
H |
0.4789 |
|
109 |
V |
H |
0.0000 |
|
110 |
T |
H |
0.0000 |
|
111 |
V |
H |
0.0000 |
|
112 |
S |
H |
-0.6754 |
|
113 |
S |
H |
-0.4038 |
|
114 |
A |
H |
-0.3552 |
|
115 |
S |
H |
-0.4673 |
|
116 |
T |
H |
-0.6423 |
|
117 |
K |
H |
-1.2860 |
|
118 |
G |
H |
-1.4402 |
|
119 |
P |
H |
-0.5330 |
|
120 |
S |
H |
-0.0378 |
|
121 |
V |
H |
0.0000 |
|
122 |
F |
H |
1.0712 |
|
123 |
P |
H |
0.1182 |
|
124 |
L |
H |
0.4706 |
|
125 |
A |
H |
-0.6885 |
|
126 |
P |
H |
0.0000 |
|
127 |
C |
H |
0.2858 |
|
134 |
S |
H |
-0.3639 |
|
135 |
T |
H |
-0.2261 |
|
136 |
A |
H |
0.0000 |
|
137 |
A |
H |
0.2412 |
|
138 |
L |
H |
0.0000 |
|
139 |
G |
H |
0.0000 |
|
140 |
C |
H |
0.0000 |
|
141 |
L |
H |
0.7764 |
|
142 |
V |
H |
0.0000 |
|
143 |
K |
H |
-0.1769 |
|
144 |
D |
H |
-0.5983 |
|
145 |
Y |
H |
0.0000 |
|
146 |
F |
H |
0.0000 |
|
147 |
P |
H |
0.0000 |
|
148 |
E |
H |
-0.3406 |
|
149 |
P |
H |
-0.8009 |
|
150 |
V |
H |
-0.5444 |
|
151 |
T |
H |
-0.5523 |
|
152 |
V |
H |
-0.1574 |
|
153 |
S |
H |
-0.4577 |
|
154 |
W |
H |
0.0000 |
|
155 |
N |
H |
-0.9884 |
|
156 |
S |
H |
-0.7462 |
|
157 |
G |
H |
-0.5489 |
|
158 |
A |
H |
-0.2496 |
|
159 |
L |
H |
-0.1323 |
|
160 |
T |
H |
-0.3681 |
|
161 |
S |
H |
-0.4374 |
|
162 |
G |
H |
-0.5656 |
|
163 |
V |
H |
-0.1870 |
|
164 |
H |
H |
-0.6195 |
|
165 |
T |
H |
0.0743 |
|
166 |
F |
H |
0.8691 |
|
167 |
P |
H |
0.5787 |
|
168 |
A |
H |
1.1956 |
|
169 |
V |
H |
2.4372 |
|
170 |
L |
H |
2.1738 |
|
171 |
Q |
H |
0.7955 |
|
172 |
S |
H |
0.1675 |
|
173 |
S |
H |
-0.1457 |
|
174 |
G |
H |
0.2592 |
|
175 |
L |
H |
0.2993 |
|
176 |
Y |
H |
0.7545 |
|
177 |
S |
H |
0.0000 |
|
178 |
L |
H |
0.0000 |
|
179 |
S |
H |
0.6238 |
|
180 |
S |
H |
0.0000 |
|
181 |
V |
H |
0.3064 |
|
182 |
V |
H |
0.0000 |
|
183 |
T |
H |
-0.2635 |
|
184 |
V |
H |
0.0000 |
|
185 |
P |
H |
-0.5048 |
|
186 |
S |
H |
-0.2533 |
|
187 |
S |
H |
-0.5478 |
|
188 |
S |
H |
-0.6435 |
|
189 |
L |
H |
-0.6840 |
|
190 |
G |
H |
-1.0033 |
|
191 |
T |
H |
-0.8847 |
|
192 |
K |
H |
-1.6539 |
|
193 |
T |
H |
-1.4309 |
|
194 |
Y |
H |
0.0000 |
|
195 |
T |
H |
-1.8894 |
|
196 |
C |
H |
0.0000 |
|
197 |
N |
H |
-1.6417 |
|
198 |
V |
H |
0.0000 |
|
199 |
D |
H |
-1.7997 |
|
200 |
H |
H |
0.0000 |
|
201 |
K |
H |
-2.7547 |
|
202 |
P |
H |
-1.7490 |
|
203 |
S |
H |
-1.8919 |
|
204 |
N |
H |
-2.5600 |
|
205 |
T |
H |
-2.0653 |
|
206 |
K |
H |
-2.6273 |
|
207 |
V |
H |
-1.8264 |
|
208 |
D |
H |
-2.8235 |
|
209 |
K |
H |
-2.3124 |
|
210 |
R |
H |
-2.8952 |
|
211 |
V |
H |
0.0000 |
|
212 |
E |
H |
-2.8842 |
|
213 |
S |
H |
-1.7135 |
|
214 |
K |
H |
-2.0979 |
|