Project name: 3o0e_modified_chains-AL.pdb_stat_DIBS

Chain sequence(s)	A: AEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVATYRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF; L: SGGDGRGHNTGAHST
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.0885
• Maximal score value: 2.6132
• Average score: -0.414
• Total score value: -146.9675

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	0.2848
2	E	A	-0.7193
3	I	A	1.1375
4	Y	A	-0.3532
5	N	A	-2.7951
6	K	A	-3.4800
7	D	A	-3.4728
8	G	A	-2.8882
9	N	A	-2.6983
10	K	A	-2.7369
11	V	A	-0.8948
12	D	A	-0.4780
13	L	A	0.8149
14	Y	A	0.6484
15	G	A	0.0000
16	K	A	-0.0064
17	A	A	0.3818
18	V	A	0.0000
19	G	A	0.1123
20	L	A	0.0000
21	H	A	-0.2624
22	Y	A	0.0000
23	F	A	0.5938
24	S	A	-1.3037
25	K	A	-2.6988
26	G	A	-2.4802
27	N	A	-2.7850
28	G	A	0.0000
29	E	A	-3.2860
30	N	A	-2.7067
31	S	A	-1.9555
32	Y	A	-0.6762
33	G	A	-0.4802
34	G	A	-1.7088
35	N	A	-1.7114
36	G	A	-1.3196
37	D	A	-2.0997
38	M	A	-1.1144
39	T	A	-0.6450
40	Y	A	-0.3670
41	A	A	0.1567
42	R	A	0.0819
43	L	A	0.9621
44	G	A	0.0000
45	F	A	0.4526
46	K	A	-1.3377
47	G	A	-1.4980
48	E	A	-2.0024
49	T	A	-1.7991
50	Q	A	-1.8690
51	I	A	-0.0003
52	N	A	-1.0342
53	S	A	-0.9388
54	D	A	-0.9842
55	L	A	0.0546
56	T	A	-0.2752
57	G	A	0.0000
58	Y	A	-0.6462
59	G	A	-0.1875
60	Q	A	-0.3835
61	W	A	0.2270
62	E	A	0.0320
63	Y	A	0.1314
64	N	A	0.0000
65	F	A	0.1210
66	Q	A	-0.7318
67	G	A	-1.3263
68	N	A	-1.7927
69	N	A	-2.0498
70	S	A	-2.0866
71	E	A	-2.7126
72	G	A	-1.9658
73	A	A	-1.4263
74	D	A	-2.2379
75	A	A	-2.2456
76	Q	A	-2.3107
77	T	A	-1.5033
78	G	A	-1.1934
79	N	A	-1.2625
80	K	A	-1.6619
81	T	A	-0.6603
82	R	A	-0.6575
83	L	A	0.0000
84	A	A	0.1364
85	F	A	0.5092
86	A	A	0.5433
87	G	A	0.9462
88	L	A	1.5325
89	K	A	0.7585
90	Y	A	1.0408
91	A	A	-0.1228
92	D	A	-0.5288
93	V	A	1.1681
94	G	A	0.8062
95	S	A	0.0000
96	F	A	2.1101
97	D	A	0.0000
98	Y	A	1.7450
99	G	A	0.4676
100	R	A	-0.0806
101	N	A	0.0163
102	Y	A	-0.0614
103	G	A	0.0000
104	V	A	0.0000
105	V	A	0.0000
106	Y	A	0.0000
107	D	A	-0.4751
108	A	A	0.0000
109	L	A	0.0000
110	G	A	0.0000
111	Y	A	0.1934
112	T	A	0.0000
113	D	A	0.0000
114	M	A	0.0911
115	L	A	0.0000
116	P	A	0.0000
117	E	A	0.2038
118	F	A	0.0000
119	G	A	0.0000
120	G	A	0.0000
121	D	A	0.0000
122	T	A	0.0000
123	A	A	0.0000
124	Y	A	0.0000
125	S	A	-0.5006
126	D	A	-0.8308
127	D	A	0.0000
128	F	A	0.0000
129	F	A	0.0000
130	V	A	0.0000
131	G	A	0.0000
132	R	A	0.0000
133	V	A	0.0000
134	G	A	0.0000
135	G	A	-0.1276
136	V	A	0.0000
137	A	A	1.3383
138	T	A	0.0000
139	Y	A	1.3235
140	R	A	0.4119
141	N	A	0.0000
142	S	A	-0.1741
143	N	A	0.1358
144	F	A	1.3477
145	F	A	1.1398
146	G	A	0.3732
147	L	A	1.5032
148	V	A	0.9032
149	D	A	-0.9320
150	G	A	-0.5583
151	L	A	0.6611
152	N	A	0.2879
153	F	A	0.8861
154	A	A	0.0000
155	V	A	1.4949
156	Q	A	0.0000
157	Y	A	1.3213
158	L	A	0.0000
159	G	A	-1.3182
160	K	A	-3.1174
161	N	A	-2.8649
162	E	A	-3.3924
163	R	A	-3.1133
164	D	A	-2.7835
165	T	A	-1.7927
166	A	A	-1.6180
167	R	A	-1.2817
168	R	A	-2.4527
169	S	A	0.0000
170	N	A	0.0000
171	G	A	0.0000
172	D	A	-2.3047
173	G	A	-0.6949
174	V	A	1.6329
175	G	A	0.0000
176	G	A	1.2051
177	S	A	0.0000
178	I	A	1.7408
179	S	A	0.0000
180	Y	A	0.9228
181	E	A	-0.6168
182	Y	A	0.0907
183	E	A	-1.4116
184	G	A	-0.9698
185	F	A	0.6696
186	G	A	0.0000
187	I	A	1.7365
188	V	A	0.0000
189	G	A	0.9953
190	A	A	0.0000
191	Y	A	1.3852
192	G	A	0.0000
193	A	A	-0.6395
194	A	A	0.0000
195	D	A	-3.4734
196	R	A	0.0000
197	T	A	0.0000
198	N	A	-2.2176
199	L	A	-1.1453
200	Q	A	0.0000
201	E	A	-3.0119
202	A	A	-1.2890
203	Q	A	-1.2314
204	P	A	-1.0052
205	L	A	0.0000
206	G	A	0.0000
207	N	A	-2.8940
208	G	A	-2.9089
209	K	A	-3.8243
210	K	A	-4.0885
211	A	A	0.0000
212	E	A	-1.6432
213	Q	A	0.0000
214	W	A	0.4525
215	A	A	0.0000
216	T	A	0.7775
217	G	A	0.0000
218	L	A	1.7906
219	K	A	0.9034
220	Y	A	0.3781
221	D	A	-1.4065
222	A	A	-1.2761
223	N	A	-1.6659
224	N	A	-1.4080
225	I	A	0.0075
226	Y	A	0.0000
227	L	A	1.6268
228	A	A	0.0000
229	A	A	1.1292
230	N	A	0.0000
231	Y	A	0.5811
232	G	A	0.0000
233	E	A	-0.7666
234	T	A	0.0000
235	R	A	-2.5468
236	N	A	0.0000
237	A	A	0.0000
238	T	A	0.0000
239	P	A	-0.3081
240	I	A	0.0000
241	T	A	-0.6031
242	N	A	0.0000
243	K	A	-1.4792
244	F	A	0.4154
245	T	A	-0.2691
246	N	A	-1.3763
247	T	A	-0.8946
248	S	A	-0.8547
249	G	A	0.0000
250	F	A	0.0000
251	A	A	0.0000
252	N	A	-2.0933
253	K	A	-2.3098
254	T	A	0.0000
255	Q	A	-0.9610
256	D	A	0.0000
257	V	A	0.2961
258	L	A	0.0000
259	L	A	1.3520
260	V	A	0.0000
261	A	A	1.2364
262	Q	A	0.0000
263	Y	A	0.6260
264	Q	A	0.0965
265	F	A	0.7173
266	D	A	-0.5414
267	F	A	1.6138
268	G	A	0.0000
269	L	A	1.2300
270	R	A	0.3520
271	P	A	0.7893
272	S	A	0.0000
273	I	A	2.0982
274	A	A	0.0000
275	Y	A	1.3002
276	T	A	0.0000
277	K	A	-0.4637
278	S	A	0.0000
279	K	A	-1.3965
280	A	A	0.0000
281	K	A	-2.8027
282	D	A	-3.0493
283	V	A	0.0000
284	E	A	-1.8463
285	G	A	-1.2808
286	I	A	-1.3317
287	G	A	-2.2688
288	D	A	-3.0301
289	V	A	0.0000
290	D	A	-1.8340
291	L	A	-0.6846
292	V	A	0.0000
293	N	A	-0.6807
294	Y	A	0.0000
295	F	A	1.8614
296	E	A	0.0000
297	V	A	2.6132
298	G	A	1.5140
299	A	A	0.9970
300	T	A	0.0000
301	Y	A	1.6466
302	Y	A	1.0646
303	F	A	1.2810
304	N	A	-0.8448
305	K	A	-1.7721
306	N	A	-0.6960
307	M	A	0.5331
308	S	A	0.0000
309	T	A	1.6555
310	Y	A	0.0000
311	V	A	2.1491
312	D	A	0.0000
313	Y	A	2.1809
314	I	A	0.0000
315	I	A	1.0359
316	N	A	-0.6336
317	Q	A	-1.7033
318	I	A	0.0000
319	D	A	-3.2816
320	S	A	-2.6076
321	D	A	-3.0163
322	N	A	-2.5140
323	K	A	-2.6720
324	L	A	0.0000
325	G	A	-1.3332
326	V	A	-1.3609
327	G	A	-1.5984
328	S	A	-1.9909
329	D	A	-2.1291
330	D	A	-0.8500
331	T	A	0.0000
332	V	A	1.5659
333	A	A	0.0000
334	V	A	1.9080
335	G	A	0.0000
336	I	A	1.8217
337	V	A	0.0000
338	Y	A	0.8440
339	Q	A	0.2048
340	F	A	0.6995
2	S	L	-0.0956
3	G	L	0.0098
4	G	L	-0.6948
5	D	L	-0.5522
6	G	L	-1.8600
7	R	L	-2.5128
8	G	L	-1.5743
9	H	L	-1.0867
10	N	L	-0.8855
11	T	L	-0.3463
12	G	L	-0.2918
13	A	L	-0.2472
14	H	L	-0.2920
15	S	L	-0.5238
16	T	L	-0.4934