Project name: dcc2a216c17f024

Chain sequence(s)	A: IDFPFAHEDVVQKTVDDVRRTLSNMSAAADQGVHDVNHSSKTLAERYKDDITALAVLPPRVDEFAKSFNDILWAGRTSATHGVSRITDFVDVTVVGIVEDIKTPEDRDAVIELNAIAGQKSKPVDGFPGATRRLDGIWNTSSTDAANIAKVKTVKELTTAFSPAKAGYKKVQEALRAYASSITKLAA
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.425
• Maximal score value: 1.8497
• Average score: -0.469
• Total score value: -87.2375

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
5	I	A	1.6727
6	D	A	-1.4071
7	F	A	0.0000
8	P	A	-0.0602
9	F	A	0.0000
10	A	A	-0.1110
11	H	A	-0.8852
12	E	A	-2.2568
13	D	A	-2.0724
14	V	A	0.0003
15	V	A	0.0000
16	Q	A	-1.3754
17	K	A	-1.9015
18	T	A	-0.2838
19	V	A	-0.1413
20	D	A	-1.9683
21	D	A	-1.0040
22	V	A	0.0000
23	R	A	-1.0154
24	T	A	-0.2455
25	L	A	0.0000
26	S	A	-0.2562
27	N	A	-1.2121
28	M	A	0.1284
29	S	A	0.0000
30	A	A	0.0420
31	A	A	0.0682
32	A	A	0.0070
33	D	A	0.0000
34	Q	A	-1.2419
35	G	A	-0.4148
36	V	A	0.1069
37	H	A	-0.5840
38	D	A	-1.3822
39	V	A	1.4588
40	N	A	-0.0214
41	H	A	-1.2087
42	S	A	-0.3876
43	S	A	0.0000
44	K	A	-1.1392
45	T	A	-0.3624
46	L	A	0.5166
47	A	A	0.0000
48	E	A	-2.3328
49	R	A	-2.0846
50	Y	A	-0.1095
51	K	A	-2.1150
52	D	A	-2.4250
53	D	A	-1.9468
54	I	A	0.5862
55	T	A	0.1103
56	A	A	0.0964
57	L	A	0.3037
58	A	A	0.4031
59	V	A	1.8497
60	L	A	0.7132
61	P	A	0.0000
62	P	A	-0.6442
63	R	A	-1.8547
64	V	A	-0.2354
65	D	A	-0.8146
66	E	A	-1.6196
67	F	A	1.2412
68	A	A	0.0000
69	K	A	-1.7727
70	S	A	-0.3951
71	F	A	0.1711
72	N	A	-0.9409
73	D	A	-1.7535
74	I	A	0.1276
75	L	A	0.0000
76	W	A	0.1863
77	A	A	0.1476
78	G	A	0.0000
79	R	A	-0.4486
80	T	A	-0.1619
81	S	A	-0.0384
82	A	A	0.0000
83	T	A	-0.1921
84	H	A	-0.9003
85	G	A	-0.2057
86	V	A	0.0000
87	S	A	-0.1181
88	R	A	0.0000
89	I	A	0.0000
90	T	A	-0.3085
91	D	A	-1.2780
92	F	A	0.0000
93	V	A	0.0000
94	D	A	-1.5267
95	V	A	0.8285
96	T	A	0.0000
97	V	A	0.0000
98	V	A	0.7095
99	G	A	-0.0820
100	I	A	0.3212
101	V	A	0.0000
102	E	A	-1.6881
103	D	A	-1.9540
104	I	A	-0.1842
105	K	A	-1.6266
106	T	A	-0.3968
107	P	A	-0.5912
108	E	A	-2.2220
109	D	A	-1.4397
110	R	A	-1.5748
111	D	A	-2.1761
113	A	A	0.0000
114	V	A	0.6778
115	I	A	1.3886
116	E	A	-0.6442
117	L	A	0.0000
118	N	A	-1.0832
119	A	A	-0.1912
120	I	A	0.0000
121	A	A	-0.2116
122	G	A	-0.6284
123	Q	A	-1.2895
124	K	A	-1.8741
125	S	A	-0.6853
126	K	A	-1.7559
127	P	A	-0.5679
128	V	A	0.0000
129	D	A	-1.8721
130	G	A	-0.7478
131	F	A	0.0619
132	P	A	-0.2371
133	G	A	-0.1345
134	A	A	0.0000
135	T	A	-0.3728
136	R	A	-1.9343
137	R	A	-0.8201
138	L	A	0.0000
139	D	A	-0.5741
140	G	A	-0.5325
141	I	A	0.0000
142	W	A	0.0000
143	N	A	-1.2772
144	T	A	-0.2413
145	S	A	0.0000
146	S	A	-0.1810
147	T	A	-0.0565
148	D	A	0.0000
149	A	A	0.0000
150	A	A	-0.1800
151	N	A	-1.2628
152	I	A	0.0000
153	A	A	0.0000
154	K	A	-1.6089
155	V	A	-0.1738
164	K	A	-1.7104
165	T	A	-0.4969
166	V	A	0.0540
167	K	A	-1.9556
168	E	A	-2.1290
169	L	A	0.0000
170	T	A	-0.0350
171	T	A	-0.0722
172	A	A	0.0021
173	F	A	0.0000
174	S	A	-0.1586
175	P	A	-0.2080
176	A	A	0.0000
177	K	A	-0.8712
178	A	A	-0.1011
179	G	A	0.0000
180	Y	A	0.0000
181	K	A	-1.5522
182	K	A	-1.2617
183	V	A	0.0000
184	Q	A	0.0000
185	E	A	-2.0106
186	A	A	0.0000
187	L	A	0.0000
188	R	A	-2.0270
189	A	A	-0.3101
190	Y	A	0.0000
191	A	A	0.0000
192	S	A	-0.1773
193	S	A	-0.1080
194	I	A	0.0000
195	T	A	-0.3521
196	K	A	-1.6554
197	L	A	-0.0145
198	A	A	0.1206
199	A	A	0.1026