Project name: 20p_arg
Status: done
submitted: 2018-08-06 15:57:42, status changed: 2018-08-06 16:08:49
Settings
Chain sequence(s)
|
A: SELTQDPAVSVALGQTVRVTCQGDSLRSYYASWYQQKPGQAPVLVIYGKNNRPSGIPDRFSGSSSGNTASLTITGAQAEDEADYYCSSRDSSGNHWVFGGGTELTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTVQLQQSGAEVKKPGSSVRVSCKASGGTFNNNAINWVRQAPGQGLEWMGGIIPMFGTAKYSQNFQGRVAITADESTGTASMELSSLRSEDTAVYYCARSRDLLLFPHHALSPWGRGTMVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPK
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.2542
-
Maximal score value
-
2.4446
-
Average score
-
-0.7242
-
Total score value
-
-312.1205
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
2 |
S |
A |
-1.6051 |
|
3 |
E |
A |
-2.4324 |
|
4 |
L |
A |
0.0000 |
|
5 |
T |
A |
-1.5214 |
|
6 |
Q |
A |
-1.5600 |
|
7 |
D |
A |
-2.4128 |
|
8 |
P |
A |
-1.7633 |
|
9 |
A |
A |
-1.3840 |
|
10 |
V |
A |
-0.9890 |
|
11 |
S |
A |
-0.3303 |
|
12 |
V |
A |
0.0000 |
|
13 |
A |
A |
-0.0887 |
|
14 |
L |
A |
-0.1483 |
|
15 |
G |
A |
-0.9927 |
|
16 |
Q |
A |
-1.3521 |
|
17 |
T |
A |
-1.1783 |
|
18 |
V |
A |
0.0000 |
|
19 |
R |
A |
-1.8950 |
|
20 |
V |
A |
0.0000 |
|
21 |
T |
A |
-1.1721 |
|
22 |
C |
A |
0.0000 |
|
23 |
Q |
A |
-2.2619 |
|
24 |
G |
A |
-2.5114 |
|
25 |
D |
A |
-3.2542 |
|
26 |
S |
A |
0.0000 |
|
27 |
L |
A |
0.0000 |
|
28 |
R |
A |
-2.8666 |
|
29 |
S |
A |
-1.4476 |
|
30 |
Y |
A |
-0.8773 |
|
31 |
Y |
A |
-0.4645 |
|
32 |
A |
A |
0.0000 |
|
33 |
S |
A |
0.0000 |
|
34 |
W |
A |
0.0000 |
|
35 |
Y |
A |
0.0000 |
|
36 |
Q |
A |
0.0000 |
|
37 |
Q |
A |
0.0000 |
|
38 |
K |
A |
-1.3550 |
|
39 |
P |
A |
-1.2237 |
|
40 |
G |
A |
-1.3079 |
|
41 |
Q |
A |
-1.3813 |
|
42 |
A |
A |
-0.8099 |
|
43 |
P |
A |
0.0000 |
|
44 |
V |
A |
0.8695 |
|
45 |
L |
A |
0.0000 |
|
46 |
V |
A |
0.0000 |
|
47 |
I |
A |
0.0000 |
|
48 |
Y |
A |
-1.1283 |
|
49 |
G |
A |
0.0000 |
|
50 |
K |
A |
-2.4833 |
|
51 |
N |
A |
-2.2205 |
|
52 |
N |
A |
-2.1119 |
|
53 |
R |
A |
-2.2268 |
|
54 |
P |
A |
-0.7935 |
|
55 |
S |
A |
-0.7504 |
|
56 |
G |
A |
-0.9059 |
|
57 |
I |
A |
-0.8455 |
|
58 |
P |
A |
-1.3590 |
|
59 |
D |
A |
-2.2109 |
|
60 |
R |
A |
-1.4341 |
|
61 |
F |
A |
0.0000 |
|
62 |
S |
A |
-1.4694 |
|
63 |
G |
A |
-1.3200 |
|
64 |
S |
A |
-1.0543 |
|
65 |
S |
A |
-1.1051 |
|
66 |
S |
A |
-1.1228 |
|
67 |
G |
A |
-1.9220 |
|
68 |
N |
A |
-2.2462 |
|
69 |
T |
A |
-1.5289 |
|
70 |
A |
A |
0.0000 |
|
71 |
S |
A |
0.0000 |
|
72 |
L |
A |
0.0000 |
|
73 |
T |
A |
-0.9592 |
|
74 |
I |
A |
0.0000 |
|
75 |
T |
A |
-1.2247 |
|
76 |
G |
A |
-0.9411 |
|
77 |
A |
A |
0.0000 |
|
78 |
Q |
A |
-1.3323 |
|
79 |
A |
A |
0.0000 |
|
80 |
E |
A |
-2.0712 |
|
81 |
D |
A |
0.0000 |
|
82 |
E |
A |
-1.8499 |
|
83 |
A |
A |
0.0000 |
|
84 |
D |
A |
-1.8016 |
|
85 |
Y |
A |
0.0000 |
|
86 |
Y |
A |
0.0000 |
|
87 |
C |
A |
0.0000 |
|
88 |
S |
A |
-0.0688 |
|
89 |
S |
A |
0.0000 |
|
90 |
R |
A |
-0.8357 |
|
91 |
D |
A |
-1.4755 |
|
92 |
S |
A |
-1.6548 |
|
93 |
S |
A |
-0.8419 |
|
94 |
G |
A |
-0.8867 |
|
95 |
N |
A |
-1.4819 |
|
96 |
H |
A |
-1.0477 |
|
97 |
W |
A |
0.0000 |
|
98 |
V |
A |
-0.4569 |
|
99 |
F |
A |
0.0000 |
|
100 |
G |
A |
0.0000 |
|
101 |
G |
A |
-1.3809 |
|
102 |
G |
A |
-1.5383 |
|
103 |
T |
A |
0.0000 |
|
104 |
E |
A |
-2.4566 |
|
105 |
L |
A |
0.0000 |
|
106 |
T |
A |
-0.5057 |
|
107 |
V |
A |
0.0000 |
|
108 |
L |
A |
0.5323 |
|
109 |
G |
A |
-0.2396 |
|
110 |
Q |
A |
0.0000 |
|
111 |
P |
A |
-0.9959 |
|
112 |
K |
A |
-2.1788 |
|
113 |
A |
A |
-1.3004 |
|
114 |
A |
A |
-0.8074 |
|
115 |
P |
A |
-0.4168 |
|
116 |
S |
A |
-0.3603 |
|
117 |
V |
A |
0.0000 |
|
118 |
T |
A |
-0.3940 |
|
119 |
L |
A |
-0.3026 |
|
120 |
F |
A |
0.0000 |
|
121 |
P |
A |
-0.1612 |
|
122 |
P |
A |
0.0000 |
|
123 |
S |
A |
-1.1692 |
|
124 |
S |
A |
-1.6785 |
|
125 |
E |
A |
-2.6103 |
|
126 |
E |
A |
0.0000 |
|
127 |
L |
A |
-2.1865 |
|
128 |
Q |
A |
-2.5428 |
|
129 |
A |
A |
-2.1169 |
|
130 |
N |
A |
-2.8301 |
|
131 |
K |
A |
-2.8847 |
|
132 |
A |
A |
0.0000 |
|
133 |
T |
A |
0.0000 |
|
134 |
L |
A |
0.0000 |
|
135 |
V |
A |
0.0000 |
|
136 |
C |
A |
0.0000 |
|
137 |
L |
A |
0.0000 |
|
138 |
I |
A |
0.0000 |
|
139 |
S |
A |
-0.6029 |
|
140 |
D |
A |
-1.1386 |
|
141 |
F |
A |
0.0000 |
|
142 |
Y |
A |
-1.1510 |
|
143 |
P |
A |
-1.0745 |
|
144 |
G |
A |
-0.6943 |
|
145 |
A |
A |
-0.2709 |
|
146 |
V |
A |
-0.0290 |
|
147 |
T |
A |
-0.0370 |
|
148 |
V |
A |
0.3609 |
|
149 |
A |
A |
-0.2210 |
|
150 |
W |
A |
0.0000 |
|
151 |
K |
A |
-1.0625 |
|
152 |
A |
A |
-1.1397 |
|
153 |
D |
A |
-1.5281 |
|
154 |
S |
A |
-0.9759 |
|
155 |
S |
A |
-0.8596 |
|
156 |
P |
A |
-0.9298 |
|
157 |
V |
A |
-0.5921 |
|
158 |
K |
A |
-1.5993 |
|
159 |
A |
A |
-0.5504 |
|
160 |
G |
A |
-0.1002 |
|
161 |
V |
A |
0.4683 |
|
162 |
E |
A |
0.2366 |
|
163 |
T |
A |
0.2560 |
|
164 |
T |
A |
0.0113 |
|
165 |
T |
A |
-0.1447 |
|
166 |
P |
A |
-0.2143 |
|
167 |
S |
A |
-0.5435 |
|
168 |
K |
A |
-1.2500 |
|
169 |
Q |
A |
-1.3068 |
|
170 |
S |
A |
-1.1559 |
|
171 |
N |
A |
-1.5695 |
|
172 |
N |
A |
-1.7224 |
|
173 |
K |
A |
-1.6438 |
|
174 |
Y |
A |
-0.7420 |
|
175 |
A |
A |
0.0000 |
|
176 |
A |
A |
0.0000 |
|
177 |
S |
A |
0.0000 |
|
178 |
S |
A |
0.0000 |
|
179 |
Y |
A |
0.0000 |
|
180 |
L |
A |
1.2888 |
|
181 |
S |
A |
0.2115 |
|
182 |
L |
A |
-0.5545 |
|
183 |
T |
A |
-1.8086 |
|
184 |
P |
A |
-2.4359 |
|
185 |
E |
A |
-3.1179 |
|
186 |
Q |
A |
-2.1677 |
|
187 |
W |
A |
0.0000 |
|
188 |
K |
A |
-3.0367 |
|
189 |
S |
A |
0.0000 |
|
190 |
H |
A |
-2.3442 |
|
191 |
R |
A |
-2.5553 |
|
192 |
S |
A |
-1.5730 |
|
193 |
Y |
A |
0.0000 |
|
194 |
S |
A |
0.0000 |
|
195 |
C |
A |
0.0000 |
|
196 |
Q |
A |
-1.1516 |
|
197 |
V |
A |
0.0000 |
|
198 |
T |
A |
-0.6700 |
|
199 |
H |
A |
0.0000 |
|
200 |
E |
A |
-2.2463 |
|
201 |
G |
A |
-1.3731 |
|
202 |
S |
A |
-0.9006 |
|
203 |
T |
A |
-0.7798 |
|
204 |
V |
A |
-0.9102 |
|
205 |
E |
A |
-2.2896 |
|
206 |
K |
A |
-1.9920 |
|
207 |
T |
A |
-1.1517 |
|
208 |
V |
A |
0.0000 |
|
209 |
A |
A |
-0.8754 |
|
210 |
P |
A |
-0.9037 |
|
2 |
V |
A |
1.1017 |
|
3 |
Q |
A |
-0.9512 |
|
4 |
L |
A |
0.0000 |
|
5 |
Q |
A |
-1.9402 |
|
6 |
Q |
A |
-1.3367 |
|
7 |
S |
A |
-1.2931 |
|
8 |
G |
A |
-1.1146 |
|
9 |
A |
A |
-0.8689 |
|
10 |
E |
A |
-1.2706 |
|
11 |
V |
A |
-0.7562 |
|
12 |
K |
A |
-1.5053 |
|
13 |
K |
A |
-2.3714 |
|
14 |
P |
A |
-1.9628 |
|
15 |
G |
A |
-1.4444 |
|
16 |
S |
A |
-1.1829 |
|
17 |
S |
A |
-1.3354 |
|
18 |
V |
A |
0.0000 |
|
19 |
R |
A |
-2.3130 |
|
20 |
V |
A |
0.0000 |
|
21 |
S |
A |
-1.0618 |
|
22 |
C |
A |
0.0000 |
|
23 |
K |
A |
-1.4224 |
|
24 |
A |
A |
0.0000 |
|
25 |
S |
A |
-0.7014 |
|
26 |
G |
A |
-0.5615 |
|
27 |
G |
A |
-0.9545 |
|
28 |
T |
A |
-1.0512 |
|
29 |
F |
A |
0.0000 |
|
30 |
N |
A |
-1.9480 |
|
31 |
N |
A |
-1.0687 |
|
32 |
N |
A |
-0.9675 |
|
33 |
A |
A |
-0.2764 |
|
34 |
I |
A |
0.0000 |
|
35 |
N |
A |
0.0000 |
|
36 |
W |
A |
0.0000 |
|
37 |
V |
A |
0.0000 |
|
38 |
R |
A |
-0.5176 |
|
39 |
Q |
A |
-0.7778 |
|
40 |
A |
A |
-1.0430 |
|
41 |
P |
A |
-0.8487 |
|
42 |
G |
A |
-1.2575 |
|
43 |
Q |
A |
-1.7899 |
|
44 |
G |
A |
-1.3328 |
|
45 |
L |
A |
0.0000 |
|
46 |
E |
A |
-0.8037 |
|
47 |
W |
A |
-0.2282 |
|
48 |
M |
A |
0.0000 |
|
49 |
G |
A |
0.0000 |
|
50 |
G |
A |
0.0000 |
|
51 |
I |
A |
0.3667 |
|
52 |
I |
A |
0.1221 |
|
53 |
P |
A |
-0.5505 |
|
54 |
M |
A |
0.1718 |
|
55 |
F |
A |
1.3060 |
|
56 |
G |
A |
0.3197 |
|
57 |
T |
A |
-0.0617 |
|
58 |
A |
A |
-0.2313 |
|
59 |
K |
A |
-1.1197 |
|
60 |
Y |
A |
-0.4242 |
|
61 |
S |
A |
-1.1403 |
|
62 |
Q |
A |
-2.0990 |
|
63 |
N |
A |
-2.1884 |
|
64 |
F |
A |
0.0000 |
|
65 |
Q |
A |
-2.1097 |
|
66 |
G |
A |
-1.4024 |
|
67 |
R |
A |
-0.9422 |
|
68 |
V |
A |
-0.5949 |
|
69 |
A |
A |
-0.5629 |
|
70 |
I |
A |
0.0000 |
|
71 |
T |
A |
-0.6116 |
|
72 |
A |
A |
-1.1722 |
|
73 |
D |
A |
-2.5731 |
|
74 |
E |
A |
-2.4381 |
|
75 |
S |
A |
-1.6016 |
|
76 |
T |
A |
-1.3281 |
|
77 |
G |
A |
0.0000 |
|
78 |
T |
A |
-1.3034 |
|
79 |
A |
A |
0.0000 |
|
80 |
S |
A |
0.0000 |
|
81 |
M |
A |
0.0000 |
|
82 |
E |
A |
-1.5892 |
|
83 |
L |
A |
0.0000 |
|
84 |
S |
A |
-1.0993 |
|
85 |
S |
A |
-1.0576 |
|
86 |
L |
A |
0.0000 |
|
87 |
R |
A |
-2.4500 |
|
88 |
S |
A |
-2.0513 |
|
89 |
E |
A |
-2.3935 |
|
90 |
D |
A |
0.0000 |
|
91 |
T |
A |
-0.9087 |
|
92 |
A |
A |
0.0000 |
|
93 |
V |
A |
-0.0123 |
|
94 |
Y |
A |
0.0000 |
|
95 |
Y |
A |
0.0000 |
|
96 |
C |
A |
0.0000 |
|
97 |
A |
A |
0.0000 |
|
98 |
R |
A |
-0.6310 |
|
99 |
S |
A |
-0.7386 |
|
100 |
R |
A |
-1.0894 |
|
101 |
D |
A |
0.2473 |
|
102 |
L |
A |
1.3026 |
|
103 |
L |
A |
2.4446 |
|
104 |
L |
A |
2.2483 |
|
105 |
F |
A |
1.1196 |
|
106 |
P |
A |
0.6471 |
|
107 |
H |
A |
-0.7442 |
|
108 |
H |
A |
-0.7500 |
|
109 |
A |
A |
0.0000 |
|
110 |
L |
A |
0.0000 |
|
111 |
S |
A |
-0.1258 |
|
112 |
P |
A |
-0.0927 |
|
113 |
W |
A |
-0.3642 |
|
114 |
G |
A |
0.0000 |
|
115 |
R |
A |
-2.3100 |
|
116 |
G |
A |
0.0000 |
|
117 |
T |
A |
0.0000 |
|
118 |
M |
A |
-0.2858 |
|
119 |
V |
A |
0.0000 |
|
120 |
T |
A |
-0.8336 |
|
121 |
V |
A |
0.0000 |
|
122 |
S |
A |
-1.0267 |
|
123 |
S |
A |
-0.9645 |
|
124 |
A |
A |
-0.5397 |
|
125 |
S |
A |
-0.6620 |
|
126 |
T |
A |
-0.6109 |
|
127 |
K |
A |
-0.8327 |
|
128 |
G |
A |
-1.2213 |
|
129 |
P |
A |
-0.5827 |
|
130 |
S |
A |
-0.2791 |
|
131 |
V |
A |
0.0000 |
|
132 |
F |
A |
-0.6493 |
|
133 |
P |
A |
-1.1743 |
|
134 |
L |
A |
0.0000 |
|
135 |
A |
A |
-1.0007 |
|
136 |
P |
A |
0.0000 |
|
137 |
S |
A |
-0.9602 |
|
138 |
S |
A |
-1.2412 |
|
139 |
K |
A |
-2.1009 |
|
140 |
S |
A |
-1.4776 |
|
141 |
T |
A |
-0.8927 |
|
142 |
S |
A |
-0.8596 |
|
143 |
G |
A |
-1.0862 |
|
144 |
G |
A |
-1.2163 |
|
145 |
T |
A |
-0.9579 |
|
146 |
A |
A |
0.0000 |
|
147 |
A |
A |
0.0000 |
|
148 |
L |
A |
0.0000 |
|
149 |
G |
A |
0.0000 |
|
150 |
C |
A |
0.0000 |
|
151 |
L |
A |
0.0000 |
|
152 |
V |
A |
0.0000 |
|
153 |
K |
A |
-0.3550 |
|
154 |
D |
A |
-0.4555 |
|
155 |
Y |
A |
0.0000 |
|
156 |
F |
A |
-0.1848 |
|
157 |
P |
A |
0.0000 |
|
158 |
E |
A |
-0.6889 |
|
159 |
P |
A |
-0.8245 |
|
160 |
V |
A |
0.0000 |
|
161 |
T |
A |
-0.5828 |
|
162 |
V |
A |
-0.3321 |
|
163 |
S |
A |
-0.3460 |
|
164 |
W |
A |
0.0000 |
|
165 |
N |
A |
-0.7075 |
|
166 |
S |
A |
-0.5717 |
|
167 |
G |
A |
-0.4200 |
|
168 |
A |
A |
-0.1711 |
|
169 |
L |
A |
0.0873 |
|
170 |
T |
A |
-0.1486 |
|
171 |
S |
A |
-0.2506 |
|
172 |
G |
A |
-0.3238 |
|
173 |
V |
A |
0.1541 |
|
174 |
H |
A |
-0.1310 |
|
175 |
T |
A |
0.0255 |
|
176 |
F |
A |
0.0000 |
|
177 |
P |
A |
-0.3187 |
|
178 |
A |
A |
0.1308 |
|
179 |
V |
A |
0.0000 |
|
180 |
L |
A |
0.9302 |
|
181 |
Q |
A |
0.1280 |
|
182 |
S |
A |
-0.1703 |
|
183 |
S |
A |
-0.2350 |
|
184 |
G |
A |
-0.0004 |
|
185 |
L |
A |
0.1387 |
|
186 |
Y |
A |
0.2234 |
|
187 |
S |
A |
0.0000 |
|
188 |
L |
A |
0.0000 |
|
189 |
S |
A |
0.0000 |
|
190 |
S |
A |
0.0000 |
|
191 |
V |
A |
0.1711 |
|
192 |
V |
A |
0.0000 |
|
193 |
T |
A |
-0.1748 |
|
194 |
V |
A |
0.0000 |
|
195 |
P |
A |
-0.7325 |
|
196 |
S |
A |
-0.9971 |
|
197 |
S |
A |
-0.8034 |
|
198 |
S |
A |
-0.5612 |
|
199 |
L |
A |
-0.9383 |
|
200 |
G |
A |
-1.0227 |
|
201 |
T |
A |
-0.7823 |
|
202 |
Q |
A |
-1.4074 |
|
203 |
T |
A |
-1.2378 |
|
204 |
Y |
A |
0.0000 |
|
205 |
I |
A |
-1.2224 |
|
206 |
C |
A |
0.0000 |
|
207 |
N |
A |
-1.3584 |
|
208 |
V |
A |
0.0000 |
|
209 |
N |
A |
-1.7680 |
|
210 |
H |
A |
0.0000 |
|
211 |
K |
A |
-2.6857 |
|
212 |
P |
A |
-1.6114 |
|
213 |
S |
A |
-1.7226 |
|
214 |
N |
A |
-2.3617 |
|
215 |
T |
A |
-1.9784 |
|
216 |
K |
A |
-2.4789 |
|
217 |
V |
A |
-1.2901 |
|
218 |
D |
A |
-2.1534 |
|
219 |
K |
A |
-2.0073 |
|
220 |
K |
A |
-2.5322 |
|
221 |
V |
A |
0.0000 |
|
222 |
E |
A |
-2.4303 |
|
223 |
P |
A |
-1.1869 |
|