Project name: 6bi0:L
Status: done
submitted: 2019-03-21 14:55:05, status changed: 2019-03-21 15:08:07
Settings
Chain sequence(s)
|
L: IQMTQSPSSLSASVGDRRVTITCRASQDVNTAVVAWYQQKPGKAPKLLIYSASFLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCCQQHYTTPPTFGQGTKVEIKRTVAAPSVFIFPPSDEEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGASQESVTEQDSKDSTYSLSSTLTLSKAAYEKHAVYACEVTHQGLSSPVTKSFNRGE
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4245
-
Maximal score value
-
2.5622
-
Average score
-
-0.7387
-
Total score value
-
-156.5967
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
2 |
I |
L |
-0.4491 |
|
3 |
Q |
L |
-1.3723 |
|
4 |
M |
L |
0.0000 |
|
5 |
T |
L |
-1.1918 |
|
6 |
Q |
L |
0.0000 |
|
7 |
S |
L |
-0.9226 |
|
8 |
P |
L |
-0.7137 |
|
9 |
S |
L |
-1.0251 |
|
10 |
S |
L |
-1.0690 |
|
11 |
L |
L |
-0.7052 |
|
12 |
S |
L |
-0.9489 |
|
13 |
A |
L |
0.0000 |
|
14 |
S |
L |
-0.6540 |
|
15 |
V |
L |
0.2522 |
|
16 |
G |
L |
-0.4952 |
|
17 |
D |
L |
-1.5653 |
|
18 |
R |
L |
-2.2325 |
|
19 |
V |
L |
0.0000 |
|
20 |
T |
L |
-0.6154 |
|
21 |
I |
L |
0.0000 |
|
22 |
T |
L |
-0.8401 |
|
23 |
C |
L |
0.0000 |
|
24 |
R |
L |
-2.9379 |
|
25 |
A |
L |
0.0000 |
|
26 |
S |
L |
-1.8035 |
|
27 |
Q |
L |
-2.5386 |
|
28 |
D |
L |
-2.7902 |
|
29 |
V |
L |
0.0000 |
|
30 |
N |
L |
-2.1339 |
|
31 |
T |
L |
-1.2337 |
|
32 |
A |
L |
-0.4600 |
|
33 |
V |
L |
0.0000 |
|
34 |
A |
L |
0.6999 |
|
35 |
W |
L |
0.0000 |
|
36 |
Y |
L |
0.0190 |
|
37 |
Q |
L |
0.0000 |
|
38 |
Q |
L |
-1.5803 |
|
39 |
K |
L |
-1.7572 |
|
40 |
P |
L |
-1.5055 |
|
41 |
G |
L |
-1.5580 |
|
42 |
K |
L |
-2.4257 |
|
43 |
A |
L |
-1.4751 |
|
44 |
P |
L |
-1.4340 |
|
45 |
K |
L |
-1.5469 |
|
46 |
L |
L |
0.0174 |
|
47 |
L |
L |
0.0000 |
|
48 |
I |
L |
0.0000 |
|
49 |
Y |
L |
1.7490 |
|
50 |
S |
L |
0.4192 |
|
51 |
A |
L |
0.0000 |
|
52 |
S |
L |
0.7326 |
|
53 |
F |
L |
2.5622 |
|
54 |
L |
L |
1.9764 |
|
55 |
Y |
L |
1.5295 |
|
56 |
S |
L |
0.4232 |
|
57 |
G |
L |
-0.1930 |
|
58 |
V |
L |
-0.0013 |
|
59 |
P |
L |
-0.1897 |
|
60 |
S |
L |
-0.3046 |
|
61 |
R |
L |
-0.7430 |
|
62 |
F |
L |
0.0000 |
|
63 |
S |
L |
0.2256 |
|
64 |
G |
L |
-0.0377 |
|
65 |
S |
L |
-1.0648 |
|
66 |
R |
L |
-2.7089 |
|
67 |
S |
L |
-1.7561 |
|
68 |
G |
L |
-2.1517 |
|
69 |
T |
L |
-2.4785 |
|
70 |
D |
L |
-2.3279 |
|
71 |
F |
L |
0.0000 |
|
72 |
T |
L |
-1.0316 |
|
73 |
L |
L |
0.0000 |
|
74 |
T |
L |
-0.6262 |
|
75 |
I |
L |
0.0000 |
|
76 |
S |
L |
-1.3438 |
|
77 |
S |
L |
-0.9996 |
|
78 |
L |
L |
0.0000 |
|
79 |
Q |
L |
-0.8474 |
|
80 |
P |
L |
-1.4150 |
|
81 |
E |
L |
-2.1428 |
|
82 |
D |
L |
0.0000 |
|
83 |
F |
L |
-1.3143 |
|
84 |
A |
L |
0.0000 |
|
85 |
T |
L |
-1.0867 |
|
86 |
Y |
L |
0.0000 |
|
87 |
Y |
L |
-0.1004 |
|
88 |
C |
L |
0.0000 |
|
89 |
Q |
L |
0.1769 |
|
90 |
Q |
L |
0.0000 |
|
91 |
H |
L |
-0.5346 |
|
92 |
Y |
L |
0.0406 |
|
93 |
T |
L |
0.1430 |
|
94 |
T |
L |
-0.2096 |
|
95 |
P |
L |
-0.1904 |
|
96 |
P |
L |
-0.2603 |
|
97 |
T |
L |
0.0497 |
|
98 |
F |
L |
0.6855 |
|
99 |
G |
L |
0.0000 |
|
100 |
Q |
L |
-1.2189 |
|
101 |
G |
L |
0.0000 |
|
102 |
T |
L |
0.0000 |
|
103 |
K |
L |
-1.9832 |
|
104 |
V |
L |
0.0000 |
|
105 |
E |
L |
-1.2767 |
|
106 |
I |
L |
0.0000 |
|
107 |
K |
L |
-1.2793 |
|
108 |
R |
L |
-0.8585 |
|
109 |
T |
L |
-0.1973 |
|
110 |
V |
L |
0.0925 |
|
111 |
A |
L |
-0.2666 |
|
112 |
A |
L |
-0.2934 |
|
113 |
P |
L |
0.0000 |
|
114 |
S |
L |
-0.1758 |
|
115 |
V |
L |
0.0000 |
|
116 |
F |
L |
1.2671 |
|
117 |
I |
L |
1.2413 |
|
118 |
F |
L |
1.4450 |
|
119 |
P |
L |
-0.0495 |
|
120 |
P |
L |
-0.7039 |
|
121 |
S |
L |
-1.7789 |
|
122 |
D |
L |
-3.2185 |
|
123 |
E |
L |
-3.4245 |
|
124 |
Q |
L |
-2.4294 |
|
125 |
L |
L |
-2.4979 |
|
126 |
K |
L |
-3.0473 |
|
127 |
S |
L |
-1.8932 |
|
128 |
G |
L |
-1.3562 |
|
129 |
T |
L |
-1.0335 |
|
130 |
A |
L |
0.0000 |
|
131 |
S |
L |
0.0284 |
|
132 |
V |
L |
0.0000 |
|
133 |
V |
L |
0.6740 |
|
134 |
C |
L |
0.0000 |
|
135 |
L |
L |
0.4799 |
|
136 |
L |
L |
0.0000 |
|
137 |
N |
L |
-0.6809 |
|
138 |
N |
L |
-1.4508 |
|
139 |
F |
L |
0.0000 |
|
140 |
Y |
L |
0.0000 |
|
141 |
P |
L |
-1.8812 |
|
142 |
R |
L |
-2.9915 |
|
143 |
E |
L |
-3.2701 |
|
144 |
A |
L |
-2.3847 |
|
145 |
K |
L |
-2.2429 |
|
146 |
V |
L |
-1.0866 |
|
147 |
Q |
L |
-0.5433 |
|
148 |
W |
L |
0.0000 |
|
149 |
K |
L |
-0.5760 |
|
150 |
V |
L |
0.0000 |
|
151 |
D |
L |
-1.7115 |
|
152 |
N |
L |
-1.4312 |
|
153 |
A |
L |
-0.3371 |
|
154 |
L |
L |
0.6478 |
|
155 |
Q |
L |
-0.2444 |
|
156 |
S |
L |
-0.3579 |
|
157 |
G |
L |
-0.8717 |
|
158 |
A |
L |
-0.6211 |
|
159 |
S |
L |
-1.2459 |
|
160 |
Q |
L |
-2.2127 |
|
161 |
E |
L |
-2.3221 |
|
162 |
S |
L |
-1.3173 |
|
163 |
V |
L |
-0.7855 |
|
164 |
T |
L |
-1.2924 |
|
165 |
E |
L |
-2.2721 |
|
166 |
Q |
L |
0.0000 |
|
167 |
D |
L |
-2.5677 |
|
168 |
S |
L |
-2.3005 |
|
169 |
K |
L |
-2.6194 |
|
170 |
D |
L |
-1.9419 |
|
171 |
S |
L |
0.0000 |
|
172 |
T |
L |
0.0000 |
|
173 |
Y |
L |
0.0000 |
|
174 |
S |
L |
-1.0976 |
|
175 |
L |
L |
0.0000 |
|
176 |
S |
L |
-0.4758 |
|
177 |
S |
L |
0.0000 |
|
178 |
T |
L |
-0.5651 |
|
179 |
L |
L |
0.0000 |
|
180 |
T |
L |
-0.2999 |
|
181 |
L |
L |
-0.3166 |
|
182 |
S |
L |
-0.7201 |
|
183 |
K |
L |
-1.7837 |
|
184 |
A |
L |
-1.3064 |
|
185 |
A |
L |
-1.3470 |
|
186 |
Y |
L |
0.0000 |
|
187 |
E |
L |
-2.7650 |
|
188 |
K |
L |
-2.8637 |
|
189 |
H |
L |
-1.9725 |
|
190 |
A |
L |
-1.6454 |
|
191 |
V |
L |
-0.7294 |
|
192 |
Y |
L |
0.0000 |
|
193 |
A |
L |
0.0000 |
|
194 |
C |
L |
0.0000 |
|
195 |
E |
L |
-0.6448 |
|
196 |
V |
L |
0.0000 |
|
197 |
T |
L |
-1.2034 |
|
198 |
H |
L |
0.0000 |
|
199 |
Q |
L |
-1.7757 |
|
200 |
G |
L |
-0.4794 |
|
201 |
L |
L |
-0.2370 |
|
202 |
S |
L |
-0.4439 |
|
203 |
S |
L |
-0.4395 |
|
204 |
P |
L |
-0.5673 |
|
205 |
V |
L |
-0.0704 |
|
206 |
T |
L |
-0.3635 |
|
207 |
K |
L |
-0.2644 |
|
208 |
S |
L |
-0.3164 |
|
209 |
F |
L |
-0.6389 |
|
210 |
N |
L |
-1.7418 |
|
211 |
R |
L |
-2.1166 |
|
212 |
G |
L |
-1.9596 |
|
213 |
E |
L |
-2.4403 |
|