Chain sequence(s) |
A: AIKCVVVGDGAVGKTCLLISYTTNAFPGDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLLSSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVVKYLECSALTQRGLKTVFDEAIRAVL B: MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKKTVFDEAIRAVL |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
3 | A | A | -0.7391 | |
4 | I | A | 0.0000 | |
5 | K | A | -0.9643 | |
6 | C | A | 0.0000 | |
7 | V | A | 0.0000 | |
8 | V | A | 0.0000 | |
9 | V | A | 0.0000 | |
10 | G | A | 0.0000 | |
11 | D | A | -1.0312 | |
12 | G | A | -1.0711 | |
13 | A | A | -0.3573 | |
14 | V | A | 0.0000 | |
15 | G | A | -0.0667 | |
16 | K | A | 0.0000 | |
17 | T | A | -0.1846 | |
18 | C | A | 0.6561 | |
19 | L | A | 0.0000 | |
20 | L | A | 0.0000 | |
21 | I | A | 0.2853 | |
22 | S | A | 0.0000 | |
23 | Y | A | -0.1859 | |
24 | T | A | -0.5109 | |
25 | T | A | -0.3427 | |
26 | N | A | -0.7843 | |
27 | A | A | 0.2043 | |
28 | F | A | 1.2414 | |
29 | P | A | 0.4286 | |
30 | G | A | -0.2040 | |
38 | D | A | -2.3505 | |
39 | N | A | -2.0134 | |
40 | Y | A | -0.8139 | |
41 | S | A | -0.8707 | |
42 | A | A | -0.9868 | |
43 | N | A | -1.5193 | |
44 | V | A | -1.1597 | |
45 | M | A | -0.6136 | |
46 | V | A | -1.2763 | |
47 | D | A | -2.1604 | |
48 | G | A | -1.7900 | |
49 | K | A | -2.1184 | |
50 | P | A | -1.4542 | |
51 | V | A | 0.0000 | |
52 | N | A | -1.7049 | |
53 | L | A | 0.0000 | |
54 | G | A | -0.9390 | |
55 | L | A | 0.0000 | |
56 | W | A | -0.8181 | |
57 | D | A | -0.9047 | |
58 | T | A | -0.5919 | |
59 | A | A | -1.0564 | |
60 | G | A | 0.0000 | |
61 | Q | A | -2.7381 | |
62 | E | A | -3.6530 | |
63 | D | A | -3.1999 | |
64 | Y | A | -1.7892 | |
65 | D | A | -2.6151 | |
66 | R | A | -2.1726 | |
67 | L | A | -0.2742 | |
68 | R | A | 0.0000 | |
69 | P | A | 0.0732 | |
70 | L | A | 1.0735 | |
71 | S | A | 0.5352 | |
72 | Y | A | 0.0000 | |
73 | P | A | -0.7371 | |
74 | Q | A | -1.5357 | |
75 | T | A | 0.0000 | |
76 | D | A | -0.8787 | |
77 | V | A | 0.0000 | |
78 | F | A | 0.0000 | |
79 | L | A | 0.0000 | |
80 | I | A | 0.0000 | |
81 | C | A | 0.0000 | |
82 | F | A | 0.0000 | |
83 | S | A | 0.0000 | |
84 | L | A | 0.0000 | |
85 | V | A | -0.0658 | |
86 | S | A | -0.0296 | |
87 | P | A | 0.0305 | |
88 | A | A | -0.2537 | |
89 | S | A | 0.0000 | |
90 | F | A | 0.0000 | |
91 | E | A | -0.7037 | |
92 | N | A | -0.6560 | |
93 | V | A | 0.0000 | |
94 | R | A | -1.1396 | |
95 | A | A | -0.6515 | |
96 | K | A | -0.6324 | |
97 | W | A | 0.0000 | |
98 | Y | A | -0.7687 | |
99 | P | A | -0.9012 | |
100 | E | A | -1.1770 | |
101 | V | A | 0.0000 | |
102 | R | A | -1.4903 | |
103 | H | A | -1.8870 | |
104 | H | A | -1.6737 | |
105 | C | A | -1.5664 | |
106 | P | A | -1.4471 | |
107 | H | A | -1.4896 | |
108 | T | A | -0.9701 | |
109 | P | A | -0.2843 | |
110 | I | A | 0.0000 | |
111 | L | A | 0.0000 | |
112 | L | A | 0.0000 | |
113 | V | A | 0.0000 | |
114 | G | A | 0.0000 | |
115 | T | A | 0.0000 | |
116 | K | A | -0.4314 | |
117 | L | A | -0.7590 | |
118 | D | A | -1.2045 | |
119 | L | A | -1.1932 | |
120 | R | A | -1.7036 | |
121 | D | A | -2.8522 | |
122 | D | A | -3.1891 | |
123 | K | A | -3.9657 | |
124 | D | A | -4.2639 | |
125 | T | A | -3.0518 | |
126 | I | A | -3.2825 | |
127 | E | A | -5.0971 | |
128 | R | A | -4.8614 | |
129 | L | A | -3.7663 | |
130 | R | A | -4.9153 | |
131 | D | A | -4.8508 | |
132 | K | A | -4.4548 | |
133 | K | A | -3.7974 | |
134 | L | A | -2.0194 | |
135 | A | A | -1.3016 | |
136 | P | A | -0.2021 | |
137 | I | A | 0.0000 | |
138 | T | A | 0.2222 | |
139 | Y | A | 0.9099 | |
140 | P | A | 0.1526 | |
141 | Q | A | -0.2559 | |
142 | G | A | 0.0000 | |
143 | L | A | -0.2983 | |
144 | A | A | -0.9911 | |
145 | M | A | 0.0000 | |
146 | A | A | 0.0000 | |
147 | R | A | -2.7119 | |
148 | E | A | -2.8601 | |
149 | I | A | 0.0000 | |
150 | G | A | -1.5872 | |
151 | S | A | -0.7443 | |
152 | V | A | 0.0565 | |
153 | K | A | -0.4362 | |
154 | Y | A | 0.0000 | |
155 | L | A | 0.0645 | |
156 | E | A | -0.3278 | |
157 | C | A | 0.0000 | |
158 | S | A | 0.0000 | |
159 | A | A | 0.0970 | |
160 | L | A | 1.1767 | |
161 | T | A | -0.0519 | |
162 | Q | A | -1.1623 | |
163 | R | A | -2.2395 | |
164 | G | A | -1.6204 | |
165 | L | A | 0.0000 | |
166 | K | A | -2.2542 | |
167 | T | A | -1.6878 | |
168 | V | A | 0.0000 | |
169 | F | A | 0.0000 | |
170 | D | A | -2.2257 | |
171 | E | A | 0.0000 | |
172 | A | A | 0.0000 | |
173 | I | A | 0.0000 | |
174 | R | A | -1.3912 | |
175 | A | A | -0.3581 | |
176 | V | A | 0.4431 | |
177 | L | A | 1.1021 | |
1 | M | B | 0.0386 | |
2 | Q | B | -0.9028 | |
3 | A | B | -0.7396 | |
4 | I | B | 0.0000 | |
5 | K | B | -1.0804 | |
6 | C | B | 0.0000 | |
7 | V | B | 0.0000 | |
8 | V | B | 0.0000 | |
9 | V | B | 0.0000 | |
10 | G | B | 0.0000 | |
11 | D | B | -0.9600 | |
12 | G | B | -0.8944 | |
13 | A | B | -0.2706 | |
14 | V | B | 0.0000 | |
15 | G | B | -0.0311 | |
16 | K | B | 0.0000 | |
17 | T | B | 0.5033 | |
18 | C | B | 1.0470 | |
19 | L | B | 0.0000 | |
20 | L | B | 0.0000 | |
21 | I | B | 0.5028 | |
22 | S | B | 0.0000 | |
23 | Y | B | -0.4474 | |
24 | T | B | -0.4877 | |
25 | T | B | -0.3989 | |
26 | N | B | -0.8352 | |
27 | A | B | 0.1393 | |
28 | F | B | 0.9604 | |
29 | P | B | 0.4633 | |
30 | G | B | -0.5493 | |
31 | E | B | -0.8165 | |
32 | Y | B | 1.3138 | |
33 | I | B | 1.9919 | |
38 | D | B | -2.0504 | |
39 | N | B | -2.0368 | |
40 | Y | B | -0.8615 | |
41 | S | B | -0.7504 | |
42 | A | B | -0.7499 | |
43 | N | B | -1.0320 | |
44 | V | B | -0.5938 | |
45 | M | B | -0.3257 | |
46 | V | B | -1.0946 | |
47 | D | B | -2.1450 | |
48 | G | B | -1.7624 | |
49 | K | B | -2.0475 | |
50 | P | B | -1.0970 | |
51 | V | B | 0.0000 | |
52 | N | B | -0.8490 | |
53 | L | B | 0.0000 | |
54 | G | B | -0.8412 | |
55 | L | B | 0.0000 | |
56 | W | B | -0.8198 | |
57 | D | B | 0.0000 | |
58 | T | B | -0.4522 | |
59 | A | B | -0.9870 | |
60 | G | B | 0.0000 | |
61 | Q | B | -2.7427 | |
62 | E | B | -3.6295 | |
63 | D | B | -3.2073 | |
64 | Y | B | -1.8746 | |
65 | D | B | -2.6454 | |
66 | R | B | -2.1633 | |
67 | L | B | -0.3964 | |
68 | R | B | 0.0000 | |
69 | P | B | 0.0946 | |
70 | L | B | 1.2106 | |
71 | S | B | 0.5905 | |
72 | Y | B | 0.0000 | |
73 | P | B | -0.7567 | |
74 | Q | B | -1.5792 | |
75 | T | B | -1.1178 | |
76 | D | B | -0.9711 | |
77 | V | B | 0.0000 | |
78 | F | B | 0.0000 | |
79 | L | B | 0.0000 | |
80 | I | B | 0.0000 | |
81 | C | B | 0.0000 | |
82 | F | B | 0.0000 | |
83 | S | B | 0.0000 | |
84 | L | B | 0.0000 | |
85 | V | B | 0.0000 | |
86 | S | B | -0.2625 | |
87 | P | B | 0.0000 | |
88 | A | B | -0.6278 | |
89 | S | B | 0.0000 | |
90 | F | B | 0.0000 | |
91 | E | B | -2.5676 | |
92 | N | B | -1.9303 | |
93 | V | B | 0.0000 | |
94 | R | B | -2.8133 | |
95 | A | B | -1.6118 | |
96 | K | B | -1.2880 | |
97 | W | B | 0.0000 | |
98 | Y | B | -1.0992 | |
99 | P | B | -1.1017 | |
100 | E | B | -1.2740 | |
101 | V | B | 0.0000 | |
102 | R | B | -1.4640 | |
103 | H | B | -1.8735 | |
104 | H | B | -1.8205 | |
105 | C | B | -1.5674 | |
106 | P | B | -1.4334 | |
107 | H | B | -1.4924 | |
108 | T | B | -0.9830 | |
109 | P | B | -0.4691 | |
110 | I | B | 0.0000 | |
111 | L | B | 0.0000 | |
112 | L | B | 0.0000 | |
113 | V | B | 0.0000 | |
114 | G | B | 0.0000 | |
115 | T | B | 0.0000 | |
116 | K | B | -0.4825 | |
117 | L | B | -0.7554 | |
118 | D | B | -1.1312 | |
119 | L | B | -1.1333 | |
120 | R | B | -1.7298 | |
121 | D | B | -2.7981 | |
122 | D | B | -3.0480 | |
123 | K | B | -3.8323 | |
124 | D | B | -4.0990 | |
125 | T | B | 0.0000 | |
126 | I | B | -3.1804 | |
127 | E | B | -4.8403 | |
128 | R | B | -4.2589 | |
129 | L | B | 0.0000 | |
130 | R | B | -4.7953 | |
131 | D | B | -4.6759 | |
132 | K | B | -4.2358 | |
133 | K | B | -3.8204 | |
134 | L | B | -2.0528 | |
135 | A | B | -1.3761 | |
136 | P | B | -0.3594 | |
137 | I | B | 0.0000 | |
138 | T | B | -0.2000 | |
139 | Y | B | -0.0571 | |
140 | P | B | -0.4595 | |
141 | Q | B | -0.5652 | |
142 | G | B | 0.0000 | |
143 | L | B | 0.0000 | |
144 | A | B | -0.9515 | |
145 | M | B | -1.6194 | |
146 | A | B | 0.0000 | |
147 | R | B | -2.1569 | |
148 | E | B | -2.6248 | |
149 | I | B | 0.0000 | |
150 | G | B | -1.9223 | |
151 | S | B | -1.1807 | |
152 | V | B | -0.9353 | |
153 | K | B | -0.7985 | |
154 | Y | B | 0.0000 | |
155 | L | B | -0.1644 | |
156 | E | B | -0.5060 | |
157 | C | B | 0.0000 | |
158 | S | B | 0.0000 | |
159 | A | B | 0.0555 | |
160 | L | B | 1.1789 | |
161 | T | B | -0.0940 | |
162 | Q | B | -1.2852 | |
163 | R | B | -2.3246 | |
164 | G | B | -1.7414 | |
165 | L | B | 0.0000 | |
166 | K | B | -2.2774 | |
167 | T | B | -1.4659 | |
168 | V | B | 0.0000 | |
169 | F | B | 0.0000 | |
170 | D | B | -1.2705 | |
171 | E | B | -1.2690 | |
172 | A | B | 0.0000 | |
173 | I | B | 0.0000 | |
174 | R | B | -1.2837 | |
175 | A | B | -0.4598 | |
176 | V | B | 0.3723 | |
177 | L | B | 1.0697 |