| Chain sequence(s) |
A: MKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSKSGVVYMSICGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVISFVCRPEAGPTNRPMLISLDKQTCTLFFSWHTPLACEPE B: AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1508 | M | A | 0.0909 | |
| 1509 | K | A | -1.6488 | |
| 1510 | S | A | -1.6128 | |
| 1511 | N | A | -1.6736 | |
| 1512 | E | A | -3.5586 | |
| 1513 | H | A | -3.6798 | |
| 1514 | D | A | -4.2911 | |
| 1515 | D | A | -3.7997 | |
| 1516 | C | A | 0.0000 | |
| 1517 | Q | A | -2.2398 | |
| 1518 | V | A | 0.0000 | |
| 1519 | T | A | -0.6232 | |
| 1520 | N | A | 0.0000 | |
| 1521 | P | A | -0.5094 | |
| 1522 | S | A | -0.5455 | |
| 1523 | T | A | -0.6802 | |
| 1524 | G | A | -0.5007 | |
| 1525 | H | A | -0.0843 | |
| 1526 | L | A | 0.6481 | |
| 1527 | F | A | 0.0000 | |
| 1528 | D | A | -0.5102 | |
| 1529 | L | A | 0.0000 | |
| 1530 | S | A | -0.8463 | |
| 1531 | S | A | -0.3113 | |
| 1532 | L | A | 0.0101 | |
| 1533 | S | A | -0.8001 | |
| 1534 | G | A | -1.5602 | |
| 1535 | R | A | -2.9671 | |
| 1536 | A | A | -1.6890 | |
| 1537 | G | A | -1.0793 | |
| 1538 | F | A | 0.0762 | |
| 1539 | T | A | 0.2416 | |
| 1540 | A | A | 0.2733 | |
| 1541 | A | A | 0.2777 | |
| 1542 | Y | A | 0.4383 | |
| 1543 | S | A | 0.0000 | |
| 1544 | K | A | -1.9558 | |
| 1545 | S | A | -1.1350 | |
| 1546 | G | A | 0.0000 | |
| 1547 | V | A | 0.5682 | |
| 1548 | V | A | 0.0000 | |
| 1549 | Y | A | -0.5344 | |
| 1550 | M | A | 0.0000 | |
| 1551 | S | A | 0.0000 | |
| 1552 | I | A | 0.0000 | |
| 1553 | C | A | -1.8805 | |
| 1554 | G | A | -1.9978 | |
| 1555 | E | A | -3.1994 | |
| 1556 | N | A | 0.0000 | |
| 1557 | E | A | -3.2439 | |
| 1558 | N | A | -2.3761 | |
| 1559 | C | A | 0.0000 | |
| 1560 | P | A | -1.4789 | |
| 1561 | P | A | -1.4534 | |
| 1562 | G | A | -1.4744 | |
| 1563 | V | A | 0.0000 | |
| 1564 | G | A | 0.0000 | |
| 1565 | A | A | 0.0000 | |
| 1566 | C | A | 0.0000 | |
| 1567 | F | A | 0.0000 | |
| 1568 | G | A | -0.5779 | |
| 1569 | Q | A | -0.5259 | |
| 1570 | T | A | -0.7656 | |
| 1571 | R | A | -1.5187 | |
| 1572 | I | A | -0.6599 | |
| 1573 | S | A | -0.9813 | |
| 1574 | V | A | 0.0000 | |
| 1575 | G | A | 0.0000 | |
| 1576 | K | A | -2.3620 | |
| 1577 | A | A | -1.9663 | |
| 1578 | N | A | -2.4231 | |
| 1579 | K | A | -3.1824 | |
| 1580 | R | A | -3.9597 | |
| 1581 | L | A | 0.0000 | |
| 1582 | R | A | -2.3877 | |
| 1583 | Y | A | -0.8161 | |
| 1584 | V | A | 0.0070 | |
| 1585 | D | A | -1.5229 | |
| 1586 | Q | A | -1.0008 | |
| 1587 | V | A | -0.1726 | |
| 1588 | L | A | 0.0000 | |
| 1589 | Q | A | -0.7940 | |
| 1590 | L | A | 0.0000 | |
| 1591 | V | A | 0.0000 | |
| 1592 | Y | A | 0.0000 | |
| 1593 | K | A | -2.3624 | |
| 1594 | D | A | -2.1682 | |
| 1595 | G | A | -1.5341 | |
| 1596 | S | A | -0.9799 | |
| 1597 | P | A | -1.0949 | |
| 1598 | C | A | 0.0000 | |
| 1599 | P | A | -1.1989 | |
| 1600 | S | A | 0.0000 | |
| 1601 | K | A | -2.4101 | |
| 1602 | S | A | -1.7558 | |
| 1603 | G | A | -1.1210 | |
| 1604 | L | A | -0.8653 | |
| 1605 | S | A | -1.0722 | |
| 1606 | Y | A | 0.0000 | |
| 1607 | K | A | -1.2789 | |
| 1608 | S | A | 0.0000 | |
| 1609 | V | A | 0.3365 | |
| 1610 | I | A | 0.0000 | |
| 1611 | S | A | 0.5207 | |
| 1612 | F | A | 0.0000 | |
| 1613 | V | A | 0.0463 | |
| 1614 | C | A | -0.3093 | |
| 1615 | R | A | -1.3706 | |
| 1616 | P | A | -1.4465 | |
| 1617 | E | A | -2.2822 | |
| 1618 | A | A | -1.5706 | |
| 1619 | G | A | -1.5438 | |
| 1620 | P | A | -1.0333 | |
| 1621 | T | A | -1.2358 | |
| 1622 | N | A | -1.8396 | |
| 1623 | R | A | -2.0766 | |
| 1624 | P | A | 0.0000 | |
| 1625 | M | A | 0.6091 | |
| 1626 | L | A | 1.7200 | |
| 1627 | I | A | 2.5008 | |
| 1628 | S | A | 1.0228 | |
| 1629 | L | A | -0.0771 | |
| 1630 | D | A | -1.3080 | |
| 1631 | K | A | -2.2644 | |
| 1632 | Q | A | -2.2581 | |
| 1633 | T | A | -1.4921 | |
| 1634 | C | A | 0.0000 | |
| 1635 | T | A | -0.8440 | |
| 1636 | L | A | 0.0000 | |
| 1637 | F | A | 1.4689 | |
| 1638 | F | A | 0.0000 | |
| 1639 | S | A | 0.5687 | |
| 1640 | W | A | 0.0000 | |
| 1641 | H | A | -1.0614 | |
| 1642 | T | A | 0.0000 | |
| 1643 | P | A | -0.6712 | |
| 1644 | L | A | 0.3593 | |
| 1645 | A | A | 0.0000 | |
| 1646 | C | A | -0.1706 | |
| 1647 | E | A | 0.0000 | |
| 1648 | P | A | -1.2065 | |
| 1649 | E | A | -1.9436 | |
| 1 | A | B | 0.2754 | |
| 2 | Y | B | 0.1300 | |
| 3 | R | B | -1.6323 | |
| 4 | P | B | -1.1779 | |
| 5 | S | B | -0.9262 | |
| 6 | E | B | -2.0407 | |
| 7 | T | B | -0.6791 | |
| 8 | L | B | 0.5690 | |
| 9 | C | B | 0.5445 | |
| 10 | G | B | 0.4203 | |
| 11 | G | B | 0.1447 | |
| 12 | E | B | -0.1100 | |
| 13 | L | B | 0.0000 | |
| 14 | V | B | 0.9030 | |
| 15 | D | B | 0.0000 | |
| 16 | T | B | 0.3290 | |
| 17 | L | B | 0.0000 | |
| 18 | Q | B | -0.2903 | |
| 19 | F | B | 0.2509 | |
| 20 | V | B | 0.1716 | |
| 21 | C | B | 0.0000 | |
| 22 | G | B | -1.5958 | |
| 23 | D | B | -2.7537 | |
| 24 | R | B | -2.3031 | |
| 25 | G | B | -0.8007 | |
| 26 | F | B | 0.5437 | |
| 27 | Y | B | 0.6534 | |
| 28 | F | B | -0.1186 | |
| 29 | S | B | -0.9977 | |
| 30 | R | B | -1.8724 | |
| 31 | P | B | -1.5915 | |
| 32 | A | B | -1.6642 | |
| 33 | S | B | -1.4043 | |
| 34 | R | B | -1.5746 | |
| 35 | V | B | 0.0184 | |
| 36 | S | B | -1.2779 | |
| 37 | R | B | -2.3940 | |
| 38 | R | B | -3.2122 | |
| 39 | S | B | -2.5727 | |
| 40 | R | B | -2.7476 | |
| 41 | G | B | -1.5870 | |
| 42 | I | B | 0.0000 | |
| 43 | V | B | -0.9295 | |
| 44 | E | B | -2.3574 | |
| 45 | E | B | -2.3962 | |
| 46 | C | B | 0.0000 | |
| 47 | C | B | -0.5227 | |
| 48 | F | B | 0.1110 | |
| 49 | R | B | -1.9950 | |
| 50 | S | B | -1.8643 | |
| 51 | C | B | -1.5967 | |
| 52 | D | B | -2.1194 | |
| 53 | L | B | -1.3825 | |
| 54 | A | B | -0.8162 | |
| 55 | L | B | -0.0304 | |
| 56 | L | B | 0.0000 | |
| 57 | E | B | -0.3076 | |
| 58 | T | B | -0.1047 | |
| 59 | Y | B | 0.3043 | |
| 60 | C | B | 0.0000 | |
| 61 | A | B | 0.0000 | |
| 62 | T | B | 0.0000 | |
| 63 | P | B | -1.0235 | |
| 64 | A | B | -1.5026 | |
| 65 | K | B | -2.6618 | |
| 66 | S | B | -2.2129 | |
| 67 | E | B | -2.5207 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine