Project name: Sophia

Chain sequence(s)	A: GESVVATQLIPINTALTPAMMEGKVTNPSSGIPFAEMMSQIVGKQVNTPVAKGQTLMPGMVKTYVP; B: GESVVATQLIPINTALTPAMMEGKVTNPSGIPFAEMMSQIVGKQVNTPVAKGQTLLMPGMVKTY
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -1.8262
• Maximal score value: 1.7566
• Average score: -0.2047
• Total score value: -25.7875

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	G	A	-0.7459
3	E	A	-1.5185
4	S	A	0.0000
5	V	A	0.0000
6	V	A	0.0000
7	A	A	0.0000
8	T	A	-0.1495
9	Q	A	-0.8568
10	L	A	0.4414
11	I	A	0.0000
12	P	A	0.1692
13	I	A	1.7366
14	N	A	-0.9078
15	T	A	-0.2446
16	A	A	-0.0535
17	L	A	0.0000
18	T	A	-0.0782
19	P	A	-0.2256
20	A	A	0.0364
21	M	A	0.1210
22	M	A	0.0000
23	E	A	-1.3599
24	G	A	-0.7134
25	K	A	-1.5729
26	V	A	1.2263
27	T	A	0.0821
28	N	A	-1.3480
29	P	A	-0.6620
30	S	A	-0.2718
31	G	A	-0.0588
32	I	A	0.0000
33	P	A	0.0047
34	F	A	0.6138
35	A	A	0.1104
36	E	A	-0.2986
37	M	A	0.0819
38	S	A	-0.3197
39	Q	A	-0.7972
40	I	A	0.0000
41	V	A	0.5968
42	G	A	-0.3974
43	K	A	-0.4880
44	Q	A	-0.5363
45	V	A	0.0000
46	N	A	-0.5525
47	T	A	0.1303
48	P	A	0.2202
49	V	A	0.0000
50	A	A	0.0000
51	K	A	-1.8238
52	G	A	-0.7784
53	Q	A	0.0000
54	T	A	-0.0110
55	L	A	0.0000
56	M	A	0.2695
57	P	A	-0.1468
58	G	A	-0.4564
59	M	A	0.0834
60	V	A	0.0000
61	K	A	-0.7252
62	T	A	-0.1718
63	Y	A	0.4758
64	V	A	1.7566
65	P	A	0.0653
2	G	B	-0.7429
3	E	B	-1.5042
4	S	B	0.0000
5	V	B	0.0000
6	V	B	0.0000
7	A	B	0.0000
8	T	B	-0.1162
9	Q	B	-0.7298
10	L	B	0.0037
11	I	B	0.0000
12	P	B	0.0177
13	I	B	0.4968
14	N	B	-1.1393
15	T	B	-0.2428
16	A	B	-0.1076
17	L	B	0.0000
18	T	B	-0.0788
19	P	B	-0.2340
20	A	B	0.0353
21	M	B	0.1210
22	M	B	0.0000
23	E	B	-1.6335
24	G	B	-0.6720
25	K	B	-1.5586
26	V	B	1.2208
27	T	B	0.0806
28	N	B	-1.3484
29	P	B	-0.6609
30	S	B	-0.2688
31	G	B	-0.0558
32	I	B	0.0000
33	P	B	-0.0215
34	F	B	0.4543
35	A	B	0.0545
36	E	B	-0.4400
37	M	B	0.0675
38	S	B	-0.3975
39	Q	B	-1.2375
40	I	B	0.0000
41	V	B	0.6798
42	G	B	-0.3965
43	K	B	-0.5962
44	Q	B	-0.6109
45	V	B	0.0000
46	N	B	-0.7581
47	T	B	-0.0614
48	P	B	0.0000
49	V	B	0.0000
50	A	B	0.0000
51	K	B	-1.8262
52	G	B	-0.8677
53	Q	B	-0.5713
54	T	B	-0.0980
55	L	B	0.0000
56	M	B	0.2183
57	P	B	-0.1810
58	G	B	-0.4627
59	M	B	0.0759
60	V	B	0.0000
61	K	B	-0.6349
62	T	B	-0.0002
63	Y	B	0.9901