| Chain sequence(s) |
A: TLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAA P: AVPI B: LPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAA |
| Distance of aggregation | 10 Å |
| Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 5 | T | A | -0.6026 | |
| 6 | L | A | 0.0000 | |
| 7 | P | A | -0.0880 | |
| 8 | P | A | -0.3135 | |
| 9 | A | A | -0.1067 | |
| 10 | W | A | -0.0789 | |
| 11 | Q | A | -0.6246 | |
| 12 | P | A | -0.4646 | |
| 13 | F | A | 0.0000 | |
| 14 | L | A | -1.2159 | |
| 15 | K | A | -2.4266 | |
| 16 | D | A | -2.6030 | |
| 17 | H | A | -1.2997 | |
| 18 | R | A | 0.0000 | |
| 19 | I | A | -1.5909 | |
| 20 | S | A | -1.1384 | |
| 21 | T | A | -0.8024 | |
| 22 | F | A | 0.0000 | |
| 23 | K | A | -2.3354 | |
| 24 | N | A | -2.1635 | |
| 25 | W | A | 0.0000 | |
| 26 | P | A | -0.9988 | |
| 27 | F | A | -0.7152 | |
| 28 | L | A | -0.5876 | |
| 29 | E | A | -1.6054 | |
| 30 | G | A | -1.3107 | |
| 31 | C | A | -1.4887 | |
| 32 | A | A | -1.8075 | |
| 33 | C | A | 0.0000 | |
| 34 | T | A | -1.5420 | |
| 35 | P | A | 0.0000 | |
| 36 | E | A | -2.8410 | |
| 37 | R | A | -2.5152 | |
| 38 | M | A | 0.0000 | |
| 39 | A | A | 0.0000 | |
| 40 | E | A | -2.8474 | |
| 41 | A | A | 0.0000 | |
| 42 | G | A | 0.0000 | |
| 43 | F | A | 0.0000 | |
| 44 | I | A | -0.0977 | |
| 45 | H | A | 0.0000 | |
| 46 | C | A | -0.3296 | |
| 47 | P | A | -1.4570 | |
| 48 | T | A | -1.6813 | |
| 49 | E | A | -2.7355 | |
| 50 | N | A | -2.4885 | |
| 51 | E | A | -1.7107 | |
| 52 | P | A | -1.8087 | |
| 53 | D | A | -1.5309 | |
| 54 | L | A | 0.0000 | |
| 55 | A | A | 0.0000 | |
| 56 | Q | A | -0.3727 | |
| 57 | C | A | 0.0000 | |
| 58 | F | A | 0.0000 | |
| 59 | F | A | 0.0000 | |
| 60 | C | A | 0.0000 | |
| 61 | F | A | 0.0000 | |
| 62 | K | A | -0.6001 | |
| 63 | E | A | -0.0942 | |
| 64 | L | A | 0.0000 | |
| 65 | E | A | -0.1491 | |
| 66 | G | A | -0.4264 | |
| 67 | W | A | 0.0000 | |
| 68 | E | A | -2.7165 | |
| 69 | P | A | -2.0992 | |
| 70 | D | A | -2.6878 | |
| 71 | D | A | -2.3639 | |
| 72 | D | A | -2.2512 | |
| 73 | P | A | 0.0000 | |
| 74 | I | A | -1.7263 | |
| 75 | E | A | -2.9911 | |
| 76 | E | A | -2.0418 | |
| 77 | H | A | 0.0000 | |
| 78 | K | A | -2.9735 | |
| 79 | K | A | -2.9202 | |
| 80 | H | A | -1.6808 | |
| 81 | S | A | -1.6407 | |
| 82 | S | A | -1.7697 | |
| 83 | G | A | -0.9617 | |
| 84 | C | A | 0.0000 | |
| 85 | A | A | -0.1260 | |
| 86 | F | A | 0.0741 | |
| 87 | L | A | -0.1075 | |
| 88 | S | A | -0.4769 | |
| 89 | V | A | -0.9956 | |
| 90 | K | A | -2.3149 | |
| 91 | K | A | -3.0946 | |
| 92 | Q | A | -2.9996 | |
| 93 | F | A | 0.0000 | |
| 94 | E | A | -2.4627 | |
| 95 | E | A | -3.1536 | |
| 96 | L | A | 0.0000 | |
| 97 | T | A | -2.0201 | |
| 98 | L | A | 0.0000 | |
| 99 | G | A | -1.8981 | |
| 100 | E | A | -2.1644 | |
| 101 | F | A | 0.0000 | |
| 102 | L | A | 0.0000 | |
| 103 | K | A | -2.9032 | |
| 104 | L | A | 0.0000 | |
| 105 | D | A | -2.4182 | |
| 106 | R | A | -3.7028 | |
| 107 | E | A | -3.1913 | |
| 108 | R | A | -2.1567 | |
| 109 | A | A | -2.0309 | |
| 110 | K | A | -2.5813 | |
| 111 | N | A | -1.9204 | |
| 112 | K | A | -1.8260 | |
| 113 | I | A | -0.2126 | |
| 114 | A | A | -1.2592 | |
| 115 | K | A | -2.4767 | |
| 116 | E | A | -3.3199 | |
| 117 | T | A | -2.8548 | |
| 118 | N | A | -3.5161 | |
| 119 | N | A | -4.4537 | |
| 120 | K | A | -4.9124 | |
| 121 | K | A | -4.8542 | |
| 122 | K | A | -5.0523 | |
| 123 | E | A | -4.5324 | |
| 124 | F | A | -2.4265 | |
| 125 | E | A | -3.9625 | |
| 126 | E | A | -4.0478 | |
| 127 | T | A | -2.3822 | |
| 128 | A | A | -2.2363 | |
| 129 | K | A | -3.1008 | |
| 130 | K | A | -3.0614 | |
| 131 | V | A | -1.0703 | |
| 132 | R | A | -2.4819 | |
| 133 | R | A | -3.0572 | |
| 134 | A | A | -1.0265 | |
| 135 | I | A | 0.1906 | |
| 136 | E | A | -1.9288 | |
| 137 | Q | A | -1.2099 | |
| 138 | L | A | 0.6718 | |
| 139 | A | A | 0.1503 | |
| 140 | A | A | 0.0450 | |
| 6 | L | B | 1.2664 | |
| 7 | P | B | 0.4573 | |
| 8 | P | B | -0.0505 | |
| 9 | A | B | -0.0313 | |
| 10 | W | B | 0.0000 | |
| 11 | Q | B | -0.6583 | |
| 12 | P | B | -0.6124 | |
| 13 | F | B | 0.0000 | |
| 14 | L | B | -1.4404 | |
| 15 | K | B | -2.3300 | |
| 16 | D | B | -2.5977 | |
| 17 | H | B | -1.3725 | |
| 18 | R | B | 0.0000 | |
| 19 | I | B | -1.3509 | |
| 20 | S | B | -1.0505 | |
| 21 | T | B | -0.6895 | |
| 22 | F | B | -1.0200 | |
| 23 | K | B | -2.2311 | |
| 24 | N | B | -2.1282 | |
| 25 | W | B | 0.0000 | |
| 26 | P | B | -0.5148 | |
| 27 | F | B | -0.3301 | |
| 28 | L | B | -0.1874 | |
| 29 | E | B | -1.5245 | |
| 30 | G | B | -1.2032 | |
| 31 | C | B | -1.1854 | |
| 32 | A | B | -1.4861 | |
| 33 | C | B | 0.0000 | |
| 34 | T | B | -1.1731 | |
| 35 | P | B | 0.0000 | |
| 36 | E | B | -2.3513 | |
| 37 | R | B | -1.9269 | |
| 38 | M | B | 0.0000 | |
| 39 | A | B | 0.0000 | |
| 40 | E | B | -2.5732 | |
| 41 | A | B | 0.0000 | |
| 42 | G | B | 0.0000 | |
| 43 | F | B | 0.0000 | |
| 44 | I | B | -0.0914 | |
| 45 | H | B | 0.0000 | |
| 46 | C | B | -0.3630 | |
| 47 | P | B | -1.5405 | |
| 48 | T | B | -1.6603 | |
| 49 | E | B | -2.7516 | |
| 50 | N | B | -2.5494 | |
| 51 | E | B | -2.3842 | |
| 52 | P | B | -2.2262 | |
| 53 | D | B | -1.9380 | |
| 54 | L | B | 0.0000 | |
| 55 | A | B | 0.0000 | |
| 56 | Q | B | -1.1601 | |
| 57 | C | B | 0.0000 | |
| 58 | F | B | 0.0000 | |
| 59 | F | B | 0.0000 | |
| 60 | C | B | 0.0000 | |
| 61 | F | B | -1.2336 | |
| 62 | K | B | -1.7324 | |
| 63 | E | B | -2.4219 | |
| 64 | L | B | 0.0000 | |
| 65 | E | B | -2.9575 | |
| 66 | G | B | -2.0046 | |
| 67 | W | B | 0.0000 | |
| 68 | E | B | -2.8843 | |
| 69 | P | B | -1.8745 | |
| 70 | D | B | -2.6661 | |
| 71 | D | B | -2.4205 | |
| 72 | D | B | -2.0412 | |
| 73 | P | B | 0.0000 | |
| 74 | I | B | -1.5548 | |
| 75 | E | B | -2.9262 | |
| 76 | E | B | -2.3383 | |
| 77 | H | B | 0.0000 | |
| 78 | K | B | -2.9746 | |
| 79 | K | B | -3.1856 | |
| 80 | H | B | -2.4135 | |
| 81 | S | B | -1.8998 | |
| 82 | S | B | -1.8060 | |
| 83 | G | B | -1.0073 | |
| 84 | C | B | 0.0000 | |
| 85 | A | B | -0.1824 | |
| 86 | F | B | -0.0894 | |
| 87 | L | B | -0.2164 | |
| 88 | S | B | -0.4462 | |
| 89 | V | B | -0.8447 | |
| 90 | K | B | -2.0398 | |
| 91 | K | B | -2.4829 | |
| 92 | Q | B | -2.7329 | |
| 93 | F | B | 0.0000 | |
| 94 | E | B | -2.7438 | |
| 95 | E | B | -2.8914 | |
| 96 | L | B | 0.0000 | |
| 97 | T | B | -2.0667 | |
| 98 | L | B | 0.0000 | |
| 99 | G | B | -1.9122 | |
| 100 | E | B | -2.0706 | |
| 101 | F | B | 0.0000 | |
| 102 | L | B | -1.8079 | |
| 103 | K | B | -2.8986 | |
| 104 | L | B | 0.0000 | |
| 105 | D | B | -2.4073 | |
| 106 | R | B | -3.7906 | |
| 107 | E | B | -3.2789 | |
| 108 | R | B | -2.2629 | |
| 109 | A | B | -1.9384 | |
| 110 | K | B | -2.6328 | |
| 111 | N | B | -2.1914 | |
| 112 | K | B | -2.0176 | |
| 113 | I | B | -0.4985 | |
| 114 | A | B | -1.4423 | |
| 115 | K | B | -2.7915 | |
| 116 | E | B | -3.3112 | |
| 117 | T | B | -2.6873 | |
| 118 | N | B | -3.4412 | |
| 119 | N | B | -4.4633 | |
| 120 | K | B | -4.8295 | |
| 121 | K | B | -4.5267 | |
| 122 | K | B | -5.0098 | |
| 123 | E | B | -4.2700 | |
| 124 | F | B | -2.4941 | |
| 125 | E | B | -4.1832 | |
| 126 | E | B | -4.5422 | |
| 127 | T | B | -2.7794 | |
| 128 | A | B | -2.9027 | |
| 129 | K | B | -3.8662 | |
| 130 | K | B | -3.6382 | |
| 131 | V | B | -2.1627 | |
| 132 | R | B | -3.3594 | |
| 133 | R | B | -3.5548 | |
| 134 | A | B | -1.4359 | |
| 135 | I | B | -0.1433 | |
| 136 | E | B | -2.1148 | |
| 137 | Q | B | -1.2946 | |
| 138 | L | B | 0.6838 | |
| 139 | A | B | 0.3107 | |
| 140 | A | B | 0.1435 | |
| 1 | A | P | -0.0020 | |
| 2 | V | P | 1.6402 | |
| 3 | P | P | 1.2738 | |
| 4 | I | P | 1.9364 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine