Chain sequence(s) |
A: DFQGMLEEYKKEDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMMCVRHADYLNDDQKVRSLLTTSSTINSIKKVLKKRGDDFFETVSFWLSSNTCRFLHCLKQYSGEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSSDLAIQQIYQQQLVRVLENNILQPMIVSSGMLEHEGTTYTLDSILRQLNSSFHSSSVMCQHGMDPELIKQVVKQMMFYIIGAITLNNNLLLRKDMCSWSKGMQQIRYNVSQLEEWLRDKNLMMNSGAKETLEPLIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERVSVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPASLGLGFIISRV B: KKRLLSFRDVDF |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
1470 | D | A | -1.4800 | |
1471 | F | A | -0.4377 | |
1472 | Q | A | -1.3845 | |
1473 | G | A | 0.0000 | |
1474 | M | A | 0.0000 | |
1475 | L | A | 0.0000 | |
1476 | E | A | -1.6204 | |
1477 | Y | A | 0.0000 | |
1478 | K | A | -2.9806 | |
1479 | K | A | -3.2728 | |
1480 | E | A | -3.2958 | |
1481 | D | A | 0.0000 | |
1482 | E | A | 0.0000 | |
1483 | Q | A | -2.3939 | |
1484 | K | A | -2.1831 | |
1485 | L | A | 0.0000 | |
1486 | V | A | 0.0000 | |
1487 | K | A | -2.1280 | |
1488 | N | A | -2.0207 | |
1489 | L | A | 0.0000 | |
1490 | I | A | 0.0000 | |
1491 | L | A | -2.1920 | |
1492 | E | A | -2.5612 | |
1493 | L | A | 0.0000 | |
1494 | K | A | -2.7141 | |
1495 | P | A | -2.1997 | |
1496 | R | A | -2.4562 | |
1497 | G | A | -0.7161 | |
1498 | V | A | 1.1075 | |
1499 | A | A | 0.6174 | |
1500 | V | A | 0.0000 | |
1501 | N | A | -0.0946 | |
1502 | L | A | 1.4767 | |
1503 | I | A | 0.7118 | |
1504 | P | A | -0.0764 | |
1505 | G | A | 0.0000 | |
1506 | L | A | 0.0000 | |
1507 | P | A | 0.0000 | |
1508 | A | A | 0.0000 | |
1509 | Y | A | 0.0000 | |
1510 | I | A | 0.0000 | |
1511 | L | A | 0.0000 | |
1512 | F | A | 0.0000 | |
1513 | M | A | 0.0000 | |
1514 | C | A | 0.0000 | |
1515 | V | A | 0.0000 | |
1516 | R | A | 0.0000 | |
1517 | H | A | 0.0000 | |
1518 | A | A | 0.0000 | |
1519 | D | A | 0.0000 | |
1520 | Y | A | 1.2036 | |
1521 | L | A | 0.6522 | |
1522 | N | A | -0.8591 | |
1523 | D | A | -1.3886 | |
1524 | D | A | -1.7805 | |
1525 | Q | A | -2.0129 | |
1526 | K | A | 0.0000 | |
1527 | V | A | 0.0000 | |
1528 | R | A | -1.0948 | |
1529 | S | A | -0.7830 | |
1530 | L | A | 0.0000 | |
1531 | L | A | 0.0000 | |
1532 | T | A | -0.1706 | |
1533 | S | A | -0.5851 | |
1534 | T | A | 0.0000 | |
1535 | I | A | 0.0000 | |
1536 | N | A | -1.2136 | |
1537 | S | A | 0.0000 | |
1538 | I | A | 0.0000 | |
1539 | K | A | -2.5768 | |
1540 | K | A | -2.9124 | |
1541 | V | A | 0.0000 | |
1542 | L | A | 0.0000 | |
1543 | K | A | -3.6679 | |
1544 | K | A | -3.7297 | |
1545 | R | A | -3.3575 | |
1546 | G | A | -3.1338 | |
1547 | D | A | -3.4508 | |
1548 | D | A | -2.5991 | |
1549 | F | A | 0.0000 | |
1550 | E | A | -2.2210 | |
1551 | T | A | 0.0000 | |
1552 | V | A | 0.0000 | |
1553 | S | A | 0.0000 | |
1554 | F | A | 0.0000 | |
1555 | W | A | 0.0000 | |
1556 | L | A | 0.0000 | |
1557 | S | A | 0.0000 | |
1558 | N | A | 0.0000 | |
1559 | T | A | 0.0000 | |
1560 | C | A | 0.0000 | |
1561 | R | A | -0.2648 | |
1562 | F | A | 0.0000 | |
1563 | L | A | 0.0000 | |
1564 | H | A | 0.0000 | |
1565 | C | A | 0.0000 | |
1566 | L | A | 0.0000 | |
1567 | K | A | -0.7817 | |
1568 | Q | A | 0.0000 | |
1569 | Y | A | 0.0000 | |
1570 | S | A | -1.1955 | |
1571 | G | A | -1.9623 | |
1572 | E | A | -2.9614 | |
1573 | E | A | -3.1490 | |
1574 | G | A | -2.0740 | |
1575 | F | A | -1.6155 | |
1576 | M | A | -2.2093 | |
1577 | K | A | -2.7687 | |
1578 | H | A | -2.0089 | |
1579 | N | A | -1.8275 | |
1580 | T | A | -1.7217 | |
1581 | S | A | -1.9045 | |
1582 | R | A | -2.9286 | |
1583 | Q | A | 0.0000 | |
1584 | N | A | -2.6393 | |
1585 | E | A | -2.9368 | |
1586 | H | A | 0.0000 | |
1587 | C | A | -1.1454 | |
1588 | L | A | 0.0000 | |
1589 | T | A | -0.7623 | |
1590 | N | A | -1.0831 | |
1591 | F | A | 0.0000 | |
1592 | D | A | -1.1467 | |
1593 | L | A | 0.0000 | |
1594 | A | A | -0.4270 | |
1595 | E | A | -0.9161 | |
1596 | Y | A | 0.0000 | |
1597 | R | A | -1.1599 | |
1598 | Q | A | -1.7133 | |
1599 | V | A | -1.4157 | |
1600 | L | A | 0.0000 | |
1601 | S | A | -1.2137 | |
1602 | D | A | -2.0375 | |
1603 | L | A | 0.0000 | |
1604 | A | A | 0.0000 | |
1605 | I | A | -0.6186 | |
1606 | Q | A | -1.6447 | |
1607 | I | A | 0.0000 | |
1608 | Y | A | 0.0000 | |
1609 | Q | A | -1.0272 | |
1610 | Q | A | -1.2526 | |
1611 | L | A | 0.0000 | |
1612 | V | A | 0.0000 | |
1613 | R | A | -1.4938 | |
1614 | V | A | 0.0000 | |
1615 | L | A | 0.0000 | |
1616 | E | A | 0.0000 | |
1617 | N | A | -1.5888 | |
1618 | I | A | -0.3607 | |
1619 | L | A | 0.0000 | |
1620 | Q | A | -0.9409 | |
1621 | P | A | -0.6227 | |
1622 | M | A | 0.0000 | |
1623 | I | A | 0.0000 | |
1624 | V | A | -0.3205 | |
1625 | S | A | -0.9123 | |
1626 | G | A | 0.0000 | |
1627 | M | A | 0.0000 | |
1628 | L | A | 0.0000 | |
1629 | E | A | -2.2955 | |
1630 | H | A | -2.2048 | |
1631 | E | A | -2.4956 | |
1655 | G | A | -0.4435 | |
1656 | T | A | -0.2386 | |
1657 | Y | A | -0.4003 | |
1658 | T | A | -1.2645 | |
1659 | L | A | 0.0000 | |
1660 | D | A | -2.2208 | |
1661 | S | A | -1.4536 | |
1662 | I | A | 0.0000 | |
1663 | L | A | -1.5354 | |
1664 | R | A | -2.4950 | |
1665 | Q | A | -1.3740 | |
1666 | L | A | 0.0000 | |
1667 | N | A | -1.2304 | |
1668 | S | A | -0.8998 | |
1669 | F | A | 0.0000 | |
1670 | H | A | 0.0000 | |
1671 | S | A | -0.3773 | |
1672 | V | A | 0.0000 | |
1673 | M | A | 0.0000 | |
1674 | C | A | -0.0803 | |
1675 | Q | A | -1.0452 | |
1676 | H | A | 0.0000 | |
1677 | G | A | -0.5469 | |
1678 | M | A | 0.0000 | |
1679 | D | A | 0.0000 | |
1680 | P | A | -0.8881 | |
1681 | E | A | -1.3646 | |
1682 | L | A | 0.0000 | |
1683 | I | A | 0.0000 | |
1684 | K | A | -1.3506 | |
1685 | Q | A | -0.7257 | |
1686 | V | A | 0.0000 | |
1687 | V | A | 0.0000 | |
1688 | K | A | -1.0165 | |
1689 | Q | A | 0.0000 | |
1690 | M | A | 0.0000 | |
1691 | F | A | 0.0000 | |
1692 | Y | A | -0.7731 | |
1693 | I | A | 0.0000 | |
1694 | I | A | 0.0000 | |
1695 | G | A | 0.0000 | |
1696 | A | A | 0.0000 | |
1697 | I | A | -0.2799 | |
1698 | T | A | 0.0000 | |
1699 | L | A | 0.0000 | |
1700 | N | A | 0.1843 | |
1701 | N | A | 0.0410 | |
1702 | L | A | 0.0000 | |
1703 | L | A | 0.0000 | |
1704 | L | A | 0.5840 | |
1705 | R | A | -1.2824 | |
1706 | K | A | -2.6511 | |
1707 | D | A | -2.7849 | |
1708 | M | A | 0.0000 | |
1709 | C | A | 0.0000 | |
1710 | S | A | 0.0800 | |
1711 | W | A | 1.0590 | |
1712 | S | A | 0.1754 | |
1713 | K | A | -0.6904 | |
1714 | G | A | 0.0000 | |
1715 | M | A | 0.1376 | |
1716 | Q | A | -0.6808 | |
1717 | I | A | 0.0000 | |
1718 | R | A | -1.2124 | |
1719 | Y | A | -0.0408 | |
1720 | N | A | 0.0000 | |
1721 | V | A | 0.0000 | |
1722 | S | A | -0.9392 | |
1723 | Q | A | -1.3965 | |
1724 | L | A | 0.0000 | |
1725 | E | A | -2.0563 | |
1726 | E | A | -3.3973 | |
1727 | W | A | 0.0000 | |
1728 | L | A | 0.0000 | |
1729 | R | A | -4.1486 | |
1730 | D | A | -3.8080 | |
1731 | K | A | -2.8739 | |
1732 | N | A | -3.0771 | |
1733 | L | A | 0.0000 | |
1734 | M | A | -2.2143 | |
1735 | N | A | -1.9669 | |
1736 | S | A | 0.0000 | |
1737 | G | A | -1.4105 | |
1738 | A | A | 0.0000 | |
1739 | K | A | -1.9830 | |
1740 | E | A | -2.5566 | |
1741 | T | A | -1.3934 | |
1742 | L | A | 0.0000 | |
1743 | E | A | -1.5431 | |
1744 | P | A | -0.7767 | |
1745 | L | A | 0.0000 | |
1746 | I | A | -0.8338 | |
1747 | Q | A | 0.0000 | |
1748 | A | A | 0.0000 | |
1749 | A | A | 0.0000 | |
1750 | Q | A | -0.7078 | |
1751 | L | A | 0.0000 | |
1752 | L | A | 0.0000 | |
1753 | Q | A | -0.3684 | |
1754 | V | A | -0.8283 | |
1755 | K | A | -2.3310 | |
1756 | K | A | -2.6489 | |
1757 | K | A | -3.2872 | |
1758 | T | A | -2.9663 | |
1759 | D | A | -3.5914 | |
1760 | D | A | -3.8740 | |
1761 | D | A | -3.1412 | |
1762 | A | A | 0.0000 | |
1763 | E | A | -3.2928 | |
1764 | A | A | -1.8205 | |
1765 | I | A | 0.0000 | |
1766 | C | A | -1.4427 | |
1767 | S | A | -0.8372 | |
1768 | M | A | -0.5640 | |
1769 | C | A | 0.0000 | |
1770 | N | A | -1.3340 | |
1771 | A | A | -0.7441 | |
1772 | L | A | 0.0000 | |
1773 | T | A | -0.8119 | |
1774 | T | A | -1.0575 | |
1775 | A | A | -0.3457 | |
1776 | Q | A | 0.0000 | |
1777 | I | A | 0.0000 | |
1778 | V | A | -0.4117 | |
1779 | K | A | -0.4055 | |
1780 | V | A | 0.0000 | |
1781 | L | A | 0.0000 | |
1782 | N | A | -1.2387 | |
1783 | L | A | 0.0000 | |
1784 | Y | A | 0.0000 | |
1785 | T | A | -1.2496 | |
1786 | P | A | -0.9530 | |
1787 | V | A | 0.1781 | |
1788 | N | A | -1.3018 | |
1789 | E | A | -1.7513 | |
1790 | F | A | 0.1951 | |
1791 | E | A | -1.4906 | |
1792 | E | A | -3.0565 | |
1793 | R | A | -2.6780 | |
1794 | V | A | -1.5696 | |
1795 | S | A | -0.5779 | |
1796 | V | A | 0.9214 | |
1797 | S | A | -0.1753 | |
1798 | F | A | 0.0000 | |
1799 | I | A | -0.5299 | |
1800 | R | A | -1.6827 | |
1801 | T | A | -1.9389 | |
1802 | I | A | 0.0000 | |
1803 | Q | A | -2.2032 | |
1804 | M | A | -2.2149 | |
1805 | R | A | -3.3871 | |
1806 | L | A | 0.0000 | |
1807 | R | A | -3.7993 | |
1808 | D | A | -3.7786 | |
1809 | R | A | -3.2172 | |
1810 | K | A | -2.9838 | |
1811 | D | A | -2.4565 | |
1812 | S | A | -1.3580 | |
1813 | P | A | -1.1263 | |
1814 | Q | A | -1.3009 | |
1815 | L | A | -0.1153 | |
1816 | L | A | 0.1688 | |
1817 | M | A | -0.8673 | |
1818 | D | A | -2.3040 | |
1819 | A | A | -1.6140 | |
1820 | K | A | -2.4119 | |
1821 | H | A | -1.5942 | |
1822 | I | A | -0.5727 | |
1823 | F | A | 0.0583 | |
1824 | P | A | 0.0937 | |
1825 | V | A | 0.3486 | |
1826 | T | A | 0.0976 | |
1827 | F | A | 0.0832 | |
1828 | P | A | -0.1183 | |
1829 | F | A | 0.0774 | |
1830 | N | A | -0.4869 | |
1831 | P | A | -0.5792 | |
1832 | S | A | -0.2752 | |
1833 | S | A | -0.2742 | |
1834 | L | A | 0.2540 | |
1835 | A | A | -0.2759 | |
1836 | L | A | 0.0000 | |
1837 | E | A | -0.9460 | |
1838 | T | A | -0.5122 | |
1839 | I | A | 0.0000 | |
1840 | Q | A | -1.2294 | |
1841 | I | A | -0.4993 | |
1842 | P | A | 0.0720 | |
1843 | A | A | -0.2725 | |
1844 | S | A | -0.0337 | |
1845 | L | A | -0.3803 | |
1846 | G | A | -0.5432 | |
1847 | L | A | 0.0000 | |
1848 | G | A | -0.4170 | |
1849 | F | A | -0.4345 | |
1850 | I | A | 0.0000 | |
1851 | S | A | -1.1060 | |
1852 | R | A | -1.3839 | |
1853 | V | A | -0.5760 | |
185 | K | B | -2.2445 | |
186 | K | B | -1.9803 | |
187 | R | B | -1.7594 | |
188 | L | B | -0.0303 | |
189 | L | B | 0.0000 | |
190 | S | B | -0.7695 | |
191 | F | B | 0.0000 | |
192 | R | B | -2.2261 | |
193 | D | B | -1.6851 | |
194 | V | B | 0.3770 | |
195 | D | B | -0.4502 | |
196 | F | B | 0.0474 |