Project name: test10

Chain sequence(s)	A: GGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDKEGLLSMANAGSNTNGSQFFITTVPTPHLDGKHVVFGQVIKGMGVAKILENVEVKGEKPAKLCVIAECGELKEGDDWGIFPKDGSGDSHPDFPEDADVDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAELLKVKQKIKAQKDKEKAAY
Distance of aggregation	5 Å
Dynamic mode	No

• Minimal score value: -2.4514
• Maximal score value: 2.3637
• Average score: -0.4139
• Total score value: -183.3457

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-0.5546
2	G	A	-0.5947
3	S	A	0.0314
4	V	A	1.5075
5	Q	A	-0.4878
6	I	A	2.1176
7	V	A	2.3637
8	Y	A	1.1980
9	K	A	-1.4957
10	P	A	-0.0240
11	V	A	1.4309
12	D	A	-1.1658
13	L	A	1.1683
14	S	A	-0.2453
15	K	A	-1.4952
16	V	A	0.9621
17	T	A	0.1346
18	S	A	-0.5300
19	K	A	-1.6007
20	C	A	0.3278
21	G	A	-0.3691
22	S	A	-0.0637
23	L	A	1.1437
24	G	A	-0.4710
25	N	A	-1.2879
26	I	A	-0.0449
27	H	A	-1.0247
28	H	A	-1.0800
29	K	A	-1.8283
30	P	A	-0.5141
31	G	A	-0.5728
32	G	A	-0.6391
33	G	A	-0.7756
34	Q	A	-1.1039
35	V	A	0.4055
36	E	A	-1.4563
37	V	A	0.3128
38	K	A	-1.5569
39	S	A	-0.8626
40	E	A	-2.1769
41	K	A	-1.9680
42	L	A	-0.2790
43	D	A	-1.6537
44	F	A	-0.3209
45	K	A	-1.8552
46	D	A	-1.8402
47	R	A	-1.9758
48	V	A	-0.1004
49	Q	A	-1.1061
50	S	A	-0.5665
51	K	A	-1.4126
52	I	A	1.1473
53	G	A	-0.1425
54	S	A	-0.0000
55	L	A	1.1759
56	D	A	-1.5974
57	N	A	-0.4694
58	I	A	1.9176
59	T	A	0.0000
60	H	A	-0.9578
61	V	A	-0.0438
62	P	A	-0.1550
63	G	A	-0.3936
64	G	A	-0.6062
65	G	A	-0.6916
66	N	A	-1.1599
67	K	A	-2.1649
68	K	A	-1.6438
69	I	A	1.3547
70	E	A	-1.4586
71	T	A	-0.5962
72	H	A	-1.3241
73	K	A	-1.6681
74	L	A	0.8368
75	T	A	0.5121
76	F	A	1.5792
77	R	A	-1.8204
78	E	A	-2.4067
79	N	A	-1.6149
2	S	A	-0.3754
3	H	A	-0.9207
4	P	A	-0.2789
5	S	A	0.0000
6	P	A	-0.2506
7	Q	A	-1.1930
8	A	A	-0.4718
9	K	A	-1.7028
10	P	A	-0.5487
11	S	A	-0.1315
12	N	A	-0.3647
13	P	A	-0.3500
14	S	A	-0.2592
15	N	A	0.0000
16	P	A	-0.0891
17	R	A	-0.2624
18	V	A	0.0000
19	F	A	0.2044
20	F	A	0.0000
21	D	A	0.0000
22	V	A	0.0000
23	D	A	0.0000
24	I	A	0.0000
25	G	A	-0.1324
26	G	A	-0.8093
27	E	A	-2.2478
28	R	A	-2.1126
29	V	A	0.0009
30	G	A	-0.0984
31	R	A	-0.2492
32	I	A	0.0000
33	V	A	0.0000
34	L	A	0.0000
35	E	A	0.0000
36	L	A	0.0000
37	F	A	0.0000
38	A	A	-0.2910
39	D	A	-1.3315
40	I	A	0.2260
41	V	A	0.0000
42	P	A	-0.3974
43	K	A	-0.8372
44	T	A	0.0000
45	A	A	0.0000
46	E	A	-0.6572
47	N	A	0.0000
48	F	A	0.0000
49	R	A	-0.3040
50	A	A	0.0000
51	L	A	0.0000
52	C	A	0.0000
53	T	A	-0.0433
54	G	A	-0.4384
55	E	A	-2.1051
56	K	A	-1.8784
57	G	A	-0.1115
58	I	A	1.9503
59	G	A	0.0000
60	P	A	-0.2683
61	T	A	-0.1222
62	T	A	-0.0832
63	G	A	-0.5186
64	K	A	-1.3789
65	P	A	-0.1139
66	L	A	0.0000
67	H	A	-0.1943
68	F	A	0.0000
69	K	A	-1.4504
70	G	A	-0.5989
71	C	A	0.0000
72	P	A	0.0000
73	F	A	0.0000
74	H	A	0.0000
75	R	A	-0.6573
76	I	A	0.0000
77	I	A	0.1485
78	K	A	-1.9243
79	K	A	-1.9454
80	F	A	0.0510
81	M	A	0.0000
82	I	A	0.0000
83	Q	A	0.0000
84	G	A	0.0000
85	G	A	0.0000
86	D	A	0.0000
87	F	A	0.1890
88	S	A	-0.2478
89	N	A	-1.3189
90	Q	A	-0.4799
91	N	A	-0.3188
92	G	A	-0.2431
93	T	A	-0.1209
94	G	A	-0.1136
95	G	A	-0.0772
96	E	A	0.0000
97	S	A	0.0000
98	I	A	0.4141
99	Y	A	0.7194
100	G	A	-0.3107
101	E	A	-2.0634
102	K	A	-1.5625
103	F	A	0.0000
104	E	A	-2.0394
105	D	A	-0.8290
106	E	A	-0.6477
107	N	A	-0.4029
108	F	A	0.5275
109	H	A	-0.1976
110	Y	A	-0.1287
111	K	A	-0.5216
112	H	A	0.0000
113	D	A	-0.7154
114	K	A	-0.6425
115	E	A	-1.2789
116	G	A	0.0000
117	L	A	0.0000
118	L	A	0.0000
119	S	A	0.0000
120	M	A	0.0000
121	A	A	-0.0388
122	N	A	-0.2334
123	A	A	-0.0153
124	G	A	-0.1798
125	S	A	-0.4410
126	N	A	-1.4383
127	T	A	-0.2225
128	N	A	0.0000
129	G	A	0.0000
130	S	A	0.0000
131	Q	A	-0.1282
132	F	A	0.0000
133	F	A	0.0000
134	I	A	0.0000
135	T	A	0.0000
136	T	A	0.0000
137	V	A	0.0230
138	P	A	-0.2585
139	T	A	0.0000
140	P	A	-0.4361
141	H	A	-1.0367
142	L	A	0.0000
143	D	A	-0.7902
144	G	A	-0.8743
145	K	A	-1.6041
146	H	A	-0.3696
147	V	A	0.0000
148	V	A	0.0000
149	F	A	0.0000
150	G	A	0.0000
151	Q	A	0.0000
152	V	A	0.0000
153	I	A	0.0000
154	K	A	-0.2552
155	G	A	0.0000
156	M	A	0.1746
157	G	A	-0.1095
158	V	A	0.0000
159	A	A	0.0000
160	K	A	-0.4610
161	I	A	0.7830
162	L	A	0.0000
163	E	A	0.0000
164	N	A	-1.2370
165	V	A	-0.3796
166	E	A	-1.6702
167	V	A	0.1521
168	K	A	-0.6308
169	G	A	-0.7359
170	E	A	-0.9408
171	K	A	-0.4149
172	P	A	0.0000
173	A	A	-0.0774
174	K	A	-0.5906
175	L	A	-0.0428
176	C	A	0.0000
177	V	A	0.2019
178	I	A	0.0000
179	A	A	-0.1345
180	E	A	-0.7844
181	C	A	0.0000
182	G	A	-0.0989
183	E	A	-0.2762
184	L	A	0.0000
185	K	A	-2.0374
186	E	A	-2.2211
187	G	A	-1.0220
188	D	A	-1.6043
189	D	A	-1.9472
190	W	A	-0.0007
191	G	A	0.0275
192	I	A	0.4778
193	F	A	1.1944
194	P	A	-0.1365
195	K	A	-1.8364
196	D	A	-1.0993
197	G	A	-0.6014
198	S	A	-0.2154
199	G	A	-0.4743
200	D	A	0.0000
201	S	A	-0.2354
202	H	A	-0.1679
203	P	A	0.0060
204	D	A	-0.4308
205	F	A	0.1843
206	P	A	0.0000
207	E	A	-1.8598
208	D	A	-0.5502
209	A	A	-0.3658
210	D	A	-1.7545
211	V	A	-0.4763
212	D	A	-1.7197
213	L	A	-0.4458
214	K	A	-1.8937
215	D	A	-1.5725
216	V	A	0.0000
217	D	A	-1.9842
218	K	A	-1.3953
219	I	A	0.0000
220	L	A	0.5405
221	L	A	1.5948
222	I	A	0.0000
223	S	A	0.0000
224	E	A	-1.4461
225	D	A	-1.3212
226	L	A	0.0000
227	K	A	-0.5888
228	N	A	-1.2987
229	I	A	-0.0132
230	G	A	0.0000
231	N	A	-0.2742
232	T	A	-0.0769
233	F	A	0.3192
234	F	A	0.0458
235	K	A	-1.6481
236	S	A	-0.4155
237	Q	A	-0.1894
238	N	A	-0.1665
239	W	A	0.0000
240	E	A	-0.4113
241	M	A	-0.1285
242	A	A	0.0000
243	I	A	-0.0055
244	K	A	-1.6278
245	K	A	0.0000
246	Y	A	0.0000
247	T	A	-0.0263
248	K	A	0.0000
249	V	A	0.0000
250	L	A	0.1050
251	R	A	-0.4755
252	Y	A	0.0000
253	V	A	0.0000
254	E	A	-1.8321
255	G	A	-0.3999
256	S	A	0.0000
257	R	A	-1.8396
258	A	A	-0.2817
259	A	A	0.0277
260	A	A	-0.5316
261	E	A	-2.1467
262	D	A	-2.1123
263	A	A	-0.4224
264	D	A	-0.7932
265	G	A	-0.4088
266	A	A	-0.2814
267	K	A	-1.6343
268	L	A	0.0000
269	Q	A	-0.8780
270	P	A	-0.4048
271	V	A	0.0000
272	A	A	0.0000
273	L	A	0.2134
274	S	A	0.0022
275	C	A	0.0000
276	V	A	0.0000
277	L	A	0.1113
278	N	A	-0.2307
279	I	A	0.0000
280	G	A	0.0000
281	A	A	-0.0168
282	C	A	0.0000
283	K	A	-0.2074
284	L	A	-0.0461
285	K	A	-0.9960
286	M	A	-0.0902
287	S	A	-0.1965
288	D	A	-1.1402
289	W	A	-0.1778
290	Q	A	-1.0368
291	G	A	-0.2593
292	A	A	0.0000
293	V	A	0.0000
294	D	A	-1.2887
295	S	A	0.0000
296	C	A	0.0000
297	L	A	0.5322
298	E	A	-1.3190
299	A	A	0.0000
300	L	A	-0.2745
301	E	A	-1.6625
302	I	A	0.2860
303	D	A	-0.3393
304	P	A	-0.3517
305	S	A	-0.2744
306	N	A	-0.1935
307	T	A	-0.2884
308	K	A	-1.3471
309	A	A	0.0000
310	L	A	0.0000
311	Y	A	0.0902
312	R	A	-0.5507
313	R	A	-0.3078
314	A	A	0.0000
315	Q	A	-0.4606
316	G	A	0.0000
317	W	A	0.1639
318	Q	A	0.0000
319	G	A	0.0370
320	L	A	0.3225
321	K	A	-1.7374
322	E	A	-1.1534
323	Y	A	-0.3474
324	D	A	-1.8772
325	Q	A	-0.9510
326	A	A	0.0000
327	L	A	0.2920
328	A	A	0.0921
329	D	A	0.0000
330	L	A	0.0000
331	K	A	-1.4984
332	K	A	-1.0748
333	A	A	0.0000
334	Q	A	-0.5680
335	E	A	-1.6668
336	I	A	0.7127
337	A	A	0.1336
338	P	A	-0.6102
339	E	A	-1.9721
340	D	A	-1.2216
341	K	A	-1.8547
342	A	A	-0.2842
343	I	A	0.0000
344	Q	A	-0.7117
345	A	A	-0.0831
346	E	A	0.0000
347	L	A	0.0000
348	L	A	1.3039
349	K	A	-0.9972
350	V	A	0.0000
351	K	A	-1.0938
352	Q	A	-1.4928
353	K	A	-0.8515
354	I	A	0.1127
355	K	A	-1.5935
356	A	A	-0.3814
357	Q	A	-0.8009
358	K	A	-2.1195
359	D	A	-2.4138
360	K	A	-2.3682
361	E	A	-2.4514
362	K	A	-2.0257
363	A	A	-0.2366
364	A	A	0.3100
365	Y	A	1.3260