Project name: ea80d8e95d1ac3a

Status: done

submitted: 2018-04-12 18:10:23, status changed: 2018-04-16 01:02:00
Settings
Chain sequence(s) A: NYCFAGKTSSISDLKEVPRKNITLIRGLVYEGQVSPLQVAVKTLPEVCSEQDELDFLREALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEY
Distance of aggregation 10 Å
Dynamic mode No
Show buried residues

Minimal score value
-3.437
Maximal score value
1.4748
Average score
-0.5624
Total score value
-159.1558

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
1095 N A -0.9632
1096 Y A 0.0000
1097 C A -0.3212
1098 F A 0.0000
1099 A A -1.1494
1100 G A -1.2544
1101 K A -1.8015
1102 T A -1.2314
1103 S A 0.0000
1104 S A -0.1307
1105 I A 0.4836
1106 S A -0.4761
1107 D A -1.4420
1108 L A 0.0000
1109 K A -2.0653
1110 E A -1.7192
1111 V A -1.1066
1112 P A -1.3767
1113 R A -1.3915
1114 K A -1.9828
1115 N A -1.2678
1116 I A -0.4359
1117 T A -0.2610
1118 L A 0.8647
1119 I A 0.6309
1120 R A -0.5939
1121 G A 0.3177
1122 L A 1.4748
1130 V A 1.2232
1131 Y A 0.8884
1132 E A -0.0928
1133 G A 0.0000
1134 Q A -0.6386
1135 V A -0.5250
1136 S A -0.6398
1144 P A -0.3826
1145 L A -0.0917
1146 Q A -1.0663
1147 V A 0.0000
1148 A A 0.0000
1149 V A 0.0000
1150 K A -0.3820
1151 T A -0.2939
1152 L A 0.0000
1153 P A -0.6710
1154 E A -0.9437
1155 V A 0.5545
1156 C A -0.6317
1157 S A -1.6203
1158 E A -2.5610
1159 Q A -2.4781
1160 D A -2.1978
1161 E A -2.0885
1162 L A -0.8910
1163 D A -1.3987
1164 F A 0.0000
1165 L A -0.0450
1166 R A -0.5077
1167 E A -1.0676
1168 A A 0.0000
1169 L A 0.0000
1170 I A 0.0000
1171 I A 0.0000
1172 S A -1.1228
1173 K A -1.2448
1174 F A 0.0000
1175 N A -1.8857
1176 H A -1.5070
1177 Q A -1.5837
1178 N A 0.0000
1179 I A 0.0000
1180 V A 0.0000
1181 R A -1.4464
1182 C A -0.5899
1183 I A -0.0940
1184 G A 0.0000
1185 V A 0.0000
1186 S A 0.0000
1187 L A -0.5118
1188 Q A -1.1152
1189 S A -0.2852
1190 L A 0.5681
1191 P A -0.0114
1192 R A -0.7035
1193 F A 0.0000
1194 I A 0.0000
1195 L A 0.0000
1196 L A -0.2740
1197 E A -0.5091
1198 L A -0.2380
1199 M A 0.0000
1200 A A 0.2045
1201 G A -0.0094
1202 G A -0.2708
1203 D A -1.1323
1204 L A 0.0000
1205 K A -1.5746
1206 S A -1.7078
1207 F A 0.0000
1208 L A 0.0000
1209 R A -2.6145
1210 E A -2.8791
1211 T A -1.9945
1212 R A -1.6484
1213 P A 0.0000
1214 R A -0.9084
1215 P A -0.6665
1216 S A -1.0609
1217 Q A -1.7137
1218 P A -0.9991
1219 S A -0.7400
1220 S A -0.9686
1221 L A 0.0000
1222 A A -0.1748
1223 M A 0.0000
1224 L A -0.1150
1225 D A -0.6013
1226 L A 0.0000
1227 L A 0.0000
1228 H A -1.2401
1229 V A 0.0000
1230 A A 0.0000
1231 R A -1.2616
1232 D A 0.0000
1233 I A 0.0000
1234 A A 0.0000
1235 C A -0.2325
1236 G A 0.0000
1237 C A 0.0000
1238 Q A -0.8416
1239 Y A -1.1595
1240 L A 0.0000
1241 E A -1.6986
1242 E A -2.4501
1243 N A -1.6614
1244 H A -1.7431
1245 F A 0.0000
1246 I A 0.0068
1247 H A 0.0000
1248 R A 0.0705
1249 D A 0.0000
1250 I A 0.0000
1251 A A 0.0000
1252 A A 0.0000
1253 R A -2.2124
1254 N A 0.0000
1255 C A 0.0000
1256 L A -0.2828
1257 L A 0.0000
1258 T A 0.1865
1259 C A 0.2571
1260 P A -0.2407
1261 G A -0.3810
1262 P A -0.5888
1263 G A -0.6911
1264 R A -0.3206
1265 V A 0.0714
1266 A A 0.0000
1267 K A 0.0000
1268 I A 0.0000
1269 G A -0.8618
1270 D A -1.1525
1271 F A 0.0000
1272 G A -0.6446
1273 M A -0.0204
1274 A A 0.0000
1275 R A 0.0000
1276 D A -0.7918
1277 I A 1.2013
1278 Y A 1.4464
1289 A A 0.5674
1290 M A 1.4109
1291 L A 1.3619
1292 P A 0.6119
1293 V A 0.2743
1294 K A 0.0000
1295 W A 0.2506
1296 M A 0.0000
1297 P A 0.0000
1298 P A 0.0000
1299 E A -0.3324
1300 A A 0.0000
1301 F A 0.4437
1302 M A 0.2930
1303 E A -1.1263
1304 G A -0.4267
1305 I A 0.5526
1306 F A 0.4241
1307 T A 0.0883
1308 S A -0.7004
1309 K A -1.2242
1310 T A 0.0000
1311 D A 0.0000
1312 T A 0.0000
1313 W A 0.0000
1314 S A 0.0000
1315 F A 0.0000
1316 G A 0.0000
1317 V A 0.0000
1318 L A 0.0000
1319 L A 0.0000
1320 W A 0.0000
1321 E A 0.0000
1322 I A 0.0000
1323 F A 0.0000
1324 S A -0.3070
1325 L A 0.0000
1326 G A 0.0000
1327 Y A 1.1699
1328 M A 1.0256
1329 P A 0.0000
1330 Y A 0.0000
1331 P A -0.0447
1332 S A -0.8215
1333 K A -1.5640
1334 S A -1.8659
1335 N A -2.2380
1336 Q A -2.8423
1337 E A -3.2419
1338 V A 0.0000
1339 L A -1.6187
1340 E A -2.5982
1341 F A -1.4330
1342 V A 0.0000
1343 T A -0.6204
1344 S A -0.8480
1345 G A -0.9422
1346 G A -0.8080
1347 R A -0.9345
1348 M A 0.0000
1349 D A -2.1289
1350 P A -1.7879
1351 P A 0.0000
1352 K A -2.2047
1353 N A -1.3949
1354 C A -1.2223
1355 P A 0.0000
1356 G A -1.2495
1357 P A -1.2030
1358 V A 0.0000
1359 Y A -1.2935
1360 R A -2.1712
1361 I A 0.0000
1362 M A 0.0000
1363 T A -1.2700
1364 Q A -1.4589
1365 C A 0.0000
1366 W A 0.0000
1367 Q A -1.9913
1368 H A -1.9424
1369 Q A -2.7092
1370 P A -2.4443
1371 E A -3.3143
1372 D A -3.4370
1373 R A 0.0000
1374 P A 0.0000
1375 N A -1.0674
1376 F A 0.0000
1377 A A -0.4442
1378 I A -0.2809
1379 I A 0.0000
1380 L A -0.9678
1381 E A -1.7164
1382 R A -1.4643
1383 I A 0.0000
1384 E A -2.1979
1385 Y A -0.6817
1386 C A 0.0000
1387 T A -1.4664
1388 Q A -1.6566
1389 D A -1.9171
1390 P A -1.9967
1391 D A -2.6275
1392 V A 0.0000
1393 I A -1.0525
1394 N A -1.7103
1395 T A -0.9588
1396 A A -0.1762
1397 L A 0.0000
1398 P A -0.1543
1399 I A 0.6093
1400 E A 0.1105
1401 Y A 1.0630

 

Laboratory of Theory of Biopolymers 2015