Project name: 6aJL2

Chain sequence(s)	A: NFMLTQPHSVSESPGKTVTISCTRSSGSIASNYVQWYQQRPGSSPTTVIYEDNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQSYDSSNHVVFGGGTKLTVL; B: NFMLTQPHSVSESPGKTVTISCTRSSGSIASNYVQWYQQRPGSSPTTVIYEDNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQSYDSSNHVVFGGGTKLTVL
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.5146
• Maximal score value: 2.0542
• Average score: -0.5977
• Total score value: -132.6806

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	N	A	-1.5297
2	F	A	0.0000
3	M	A	0.4877
4	L	A	0.0000
5	T	A	-0.1257
6	Q	A	0.0000
7	P	A	-1.1930
8	H	A	-1.8179
9	S	A	-1.3378
10	V	A	-0.8148
11	S	A	-0.4263
12	E	A	-0.7742
13	S	A	-0.4705
14	P	A	-1.1438
15	G	A	-1.5685
16	K	A	-1.7471
17	T	A	-1.1570
18	V	A	0.0000
19	T	A	-0.1877
20	I	A	0.0000
21	S	A	-0.2110
22	C	A	0.0000
23	T	A	-0.1762
24	R	A	0.0000
25	S	A	-0.2308
26	S	A	-0.7401
27	G	A	-0.8571
28	S	A	-0.5327
29	I	A	0.0000
30	A	A	-0.1258
31	S	A	-0.1572
32	N	A	-0.1210
33	Y	A	0.5707
34	V	A	0.0000
35	Q	A	0.0000
36	W	A	0.0000
37	Y	A	0.1207
38	Q	A	-1.0409
39	Q	A	-1.7114
40	R	A	-2.3893
41	P	A	-1.4115
42	G	A	-1.1094
43	S	A	-1.1714
44	S	A	-0.8431
45	P	A	-0.7779
46	T	A	-0.4166
47	T	A	-0.2137
48	V	A	0.0000
49	I	A	0.0000
50	Y	A	-0.8911
51	E	A	-1.6725
52	D	A	-1.4271
53	N	A	-2.1509
54	Q	A	-2.2268
55	R	A	-2.2408
56	P	A	-0.9464
57	S	A	-0.7519
58	G	A	-0.8916
59	V	A	-0.9719
60	P	A	-1.3245
61	D	A	-2.2121
62	R	A	-1.3678
63	F	A	0.0000
64	S	A	-1.3464
65	G	A	-1.1575
66	S	A	-0.8932
67	I	A	-0.4943
68	D	A	-1.3518
69	S	A	-0.9489
70	S	A	-0.9194
71	S	A	-0.9999
72	N	A	0.0000
73	S	A	0.0000
74	A	A	0.0000
75	S	A	-0.4921
76	L	A	0.0000
77	T	A	-0.4295
78	I	A	0.0000
79	S	A	-1.1735
80	G	A	-1.2108
81	L	A	0.0000
82	K	A	-2.1982
83	T	A	-1.6180
84	E	A	-2.5146
85	D	A	0.0000
86	E	A	-2.2204
87	A	A	0.0000
88	D	A	-1.9983
89	Y	A	0.0000
90	Y	A	0.0521
91	C	A	0.0000
92	Q	A	0.0000
93	S	A	0.0000
94	Y	A	0.0460
95	D	A	0.0000
96	S	A	-1.1614
97	S	A	-1.2830
98	N	A	-1.7722
99	H	A	-1.4085
100	V	A	0.2600
101	V	A	0.7668
102	F	A	1.6917
103	G	A	0.0000
104	G	A	-0.4668
105	G	A	0.0000
106	T	A	0.0000
107	K	A	-2.4110
108	L	A	0.0000
109	T	A	-0.4880
110	V	A	-0.4753
111	L	A	0.9680
1	N	B	-1.2112
2	F	B	-0.0253
3	M	B	1.1739
4	L	B	0.0000
5	T	B	0.0221
6	Q	B	0.0000
7	P	B	-0.9830
8	H	B	-1.7011
9	S	B	-1.3388
10	V	B	-0.6183
11	S	B	-0.4020
12	E	B	-0.7315
13	S	B	-0.3878
14	P	B	-1.0599
15	G	B	-1.4407
16	K	B	-1.8775
17	T	B	-1.1428
18	V	B	0.0000
19	T	B	-0.1747
20	I	B	0.0000
21	S	B	-0.2470
22	C	B	0.0000
23	T	B	-0.2387
24	R	B	0.0000
25	S	B	-0.1883
26	S	B	-0.5198
27	G	B	-0.8491
28	S	B	-0.6946
29	I	B	0.0000
30	A	B	-0.1946
31	S	B	-0.2037
32	N	B	-0.1897
33	Y	B	0.6415
34	V	B	0.0000
35	Q	B	0.0000
36	W	B	0.0000
37	Y	B	0.2761
38	Q	B	0.0000
39	Q	B	-1.0460
40	R	B	-1.0284
41	P	B	-0.8982
42	G	B	-1.0351
43	S	B	0.0000
44	S	B	-0.7468
45	P	B	-0.4398
46	T	B	-0.1107
47	T	B	-0.1047
48	V	B	0.0000
49	I	B	0.0000
50	Y	B	-0.6210
51	E	B	-1.3354
52	D	B	-1.2254
53	N	B	-2.0271
54	Q	B	-2.0078
55	R	B	-1.8581
56	P	B	-0.8739
57	S	B	-0.9040
58	G	B	-0.9019
59	V	B	0.0000
60	P	B	-1.4163
61	D	B	-2.1715
62	R	B	-1.5008
63	F	B	0.0000
64	S	B	-1.3267
65	G	B	-1.0764
66	S	B	-0.8869
67	I	B	-0.5265
68	D	B	-1.4015
69	S	B	-1.0231
70	S	B	-0.8796
71	S	B	-0.8423
72	N	B	-0.9393
73	S	B	-0.6909
74	A	B	0.0000
75	S	B	-0.4933
76	L	B	0.0000
77	T	B	-0.2814
78	I	B	0.0000
79	S	B	-1.2320
80	G	B	-1.2952
81	L	B	0.0000
82	K	B	-1.4846
83	T	B	-0.9032
84	E	B	-1.0695
85	D	B	0.0000
86	E	B	-1.9036
87	A	B	0.0000
88	D	B	-1.5741
89	Y	B	0.0000
90	Y	B	0.1232
91	C	B	0.0000
92	Q	B	0.0000
93	S	B	0.0000
94	Y	B	0.5037
95	D	B	-0.7125
96	S	B	-1.1308
97	S	B	-1.2159
98	N	B	-1.5635
99	H	B	-0.9074
100	V	B	1.3932
101	V	B	1.4880
102	F	B	2.0542
103	G	B	0.5707
104	G	B	-0.4008
105	G	B	0.0000
106	T	B	0.0000
107	K	B	-2.3948
108	L	B	0.0000
109	T	B	-0.7762
110	V	B	0.0000
111	L	B	0.7536