Project name: 4JOB
Status: done
submitted: 2018-02-20 14:41:44, status changed: 2018-02-20 14:51:07
Settings
Chain sequence(s)
|
A: PVDRSLLKLKMVQVVFRHGARSPLKPLPLEEQVEWNPQLLEVPPQTQFDYTVTNLAGGPKPYSPYETTLKGGMFAGQLTKVGMQQMFALGERLRKNYVEDIPFLSPTFNPQEVFIRSTNIFRNLESTRCLLAGLFQCQKEGPIIIHTDEADSEVLYPNYQSCWSLRQRTRGRRQTASLQPGISEDLKKVKDRMGIDSSDKVDFFILLDNVAAEQAHNLPSCPMLKRRFARMIEQRAVDTSLYILPKEDRESLQMAVGPFLHILESNLLKAMDPDKIRKLYLYAAHDVTFIPLLMTLGIFDHKWPPFAVDLTMELYQHLESKEWFVQLYYHGKEQVPRGCPDGLCPLDMFLNAMSVYTLSPEKYHALCSQT
|
Distance of aggregation |
10 Å |
Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-4.0935
-
Maximal score value
-
1.9152
-
Average score
-
-0.8054
-
Total score value
-
-297.1962
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
residue index |
residue name |
chain |
Aggrescan3D score |
|
42 |
P |
A |
-0.2437 |
|
43 |
V |
A |
-0.0785 |
|
44 |
D |
A |
-1.6100 |
|
45 |
R |
A |
-2.0039 |
|
46 |
S |
A |
-1.1333 |
|
47 |
L |
A |
-1.0815 |
|
48 |
L |
A |
0.0000 |
|
49 |
K |
A |
-1.7430 |
|
50 |
L |
A |
0.0000 |
|
51 |
K |
A |
-1.3080 |
|
52 |
M |
A |
0.0000 |
|
53 |
V |
A |
0.0000 |
|
54 |
Q |
A |
0.0000 |
|
55 |
V |
A |
0.0000 |
|
56 |
V |
A |
0.0000 |
|
57 |
F |
A |
0.0000 |
|
58 |
R |
A |
0.0000 |
|
59 |
H |
A |
0.0000 |
|
60 |
G |
A |
0.0000 |
|
61 |
A |
A |
0.0000 |
|
62 |
R |
A |
0.0000 |
|
63 |
S |
A |
0.0000 |
|
64 |
P |
A |
0.0000 |
|
65 |
L |
A |
0.1301 |
|
66 |
K |
A |
-0.7607 |
|
67 |
P |
A |
-0.8029 |
|
68 |
L |
A |
0.0000 |
|
69 |
P |
A |
-1.5059 |
|
70 |
L |
A |
-1.7339 |
|
71 |
E |
A |
-2.7414 |
|
72 |
E |
A |
-3.2927 |
|
73 |
Q |
A |
-2.7064 |
|
74 |
V |
A |
-1.8473 |
|
75 |
E |
A |
-2.9451 |
|
76 |
W |
A |
0.0000 |
|
77 |
N |
A |
-1.4363 |
|
78 |
P |
A |
-1.0482 |
|
79 |
Q |
A |
-1.6856 |
|
80 |
L |
A |
-0.8227 |
|
81 |
L |
A |
-0.6300 |
|
82 |
E |
A |
-1.7553 |
|
83 |
V |
A |
-0.9795 |
|
84 |
P |
A |
-1.1117 |
|
85 |
P |
A |
-1.3031 |
|
86 |
Q |
A |
-1.7529 |
|
87 |
T |
A |
0.0000 |
|
88 |
Q |
A |
-1.9434 |
|
89 |
F |
A |
0.0000 |
|
90 |
D |
A |
-1.9813 |
|
91 |
Y |
A |
-0.6260 |
|
92 |
T |
A |
-0.1718 |
|
93 |
V |
A |
-0.0080 |
|
94 |
T |
A |
-0.5338 |
|
95 |
N |
A |
-0.9344 |
|
96 |
L |
A |
-0.2100 |
|
97 |
A |
A |
-0.2436 |
|
98 |
G |
A |
-0.5532 |
|
99 |
G |
A |
-0.7820 |
|
100 |
P |
A |
-0.7415 |
|
101 |
K |
A |
-1.1912 |
|
102 |
P |
A |
-0.5898 |
|
103 |
Y |
A |
0.7292 |
|
104 |
S |
A |
0.7228 |
|
105 |
P |
A |
0.2705 |
|
106 |
Y |
A |
1.3337 |
|
112 |
E |
A |
-1.2250 |
|
113 |
T |
A |
-0.6038 |
|
114 |
T |
A |
-0.3714 |
|
115 |
L |
A |
0.0000 |
|
116 |
K |
A |
-2.6822 |
|
117 |
G |
A |
-1.9993 |
|
118 |
G |
A |
-1.0725 |
|
119 |
M |
A |
0.0000 |
|
120 |
F |
A |
0.7904 |
|
121 |
A |
A |
0.0752 |
|
122 |
G |
A |
0.0000 |
|
123 |
Q |
A |
0.5273 |
|
124 |
L |
A |
0.0000 |
|
125 |
T |
A |
0.0000 |
|
126 |
K |
A |
-0.8882 |
|
127 |
V |
A |
-0.0572 |
|
128 |
G |
A |
0.0000 |
|
129 |
M |
A |
0.0000 |
|
130 |
Q |
A |
-1.2561 |
|
131 |
Q |
A |
-0.8656 |
|
132 |
M |
A |
0.0000 |
|
133 |
F |
A |
-0.8342 |
|
134 |
A |
A |
-0.8417 |
|
135 |
L |
A |
0.0000 |
|
136 |
G |
A |
0.0000 |
|
137 |
E |
A |
-1.9689 |
|
138 |
R |
A |
-1.9262 |
|
139 |
L |
A |
0.0000 |
|
140 |
R |
A |
-2.4751 |
|
141 |
K |
A |
-3.4250 |
|
142 |
N |
A |
-2.3338 |
|
143 |
Y |
A |
0.0000 |
|
144 |
V |
A |
0.0000 |
|
145 |
E |
A |
-3.2984 |
|
146 |
D |
A |
-2.9345 |
|
147 |
I |
A |
-1.1370 |
|
148 |
P |
A |
-1.0383 |
|
149 |
F |
A |
0.0000 |
|
150 |
L |
A |
0.0000 |
|
151 |
S |
A |
-0.8932 |
|
152 |
P |
A |
-1.0208 |
|
153 |
T |
A |
-1.3999 |
|
154 |
F |
A |
0.0000 |
|
155 |
N |
A |
-1.7644 |
|
156 |
P |
A |
-1.2967 |
|
157 |
Q |
A |
-2.0453 |
|
158 |
E |
A |
-1.3705 |
|
159 |
V |
A |
0.0000 |
|
160 |
F |
A |
-0.0725 |
|
161 |
I |
A |
0.0000 |
|
162 |
R |
A |
0.0000 |
|
163 |
S |
A |
0.0000 |
|
164 |
T |
A |
0.0000 |
|
165 |
N |
A |
0.0000 |
|
166 |
I |
A |
0.0000 |
|
167 |
F |
A |
1.9152 |
|
168 |
R |
A |
0.5511 |
|
169 |
N |
A |
0.0000 |
|
170 |
L |
A |
0.0000 |
|
171 |
E |
A |
0.1845 |
|
172 |
S |
A |
0.0000 |
|
173 |
T |
A |
0.0000 |
|
174 |
R |
A |
0.0000 |
|
175 |
C |
A |
0.0000 |
|
176 |
L |
A |
0.0000 |
|
177 |
L |
A |
0.0000 |
|
178 |
A |
A |
0.0000 |
|
179 |
G |
A |
0.0000 |
|
180 |
L |
A |
0.0000 |
|
181 |
F |
A |
0.0000 |
|
182 |
Q |
A |
-1.4162 |
|
183 |
C |
A |
-1.4387 |
|
184 |
Q |
A |
-1.9234 |
|
185 |
K |
A |
-2.5845 |
|
186 |
E |
A |
-2.6149 |
|
187 |
G |
A |
-1.6532 |
|
188 |
P |
A |
-0.9905 |
|
189 |
I |
A |
0.0000 |
|
190 |
I |
A |
0.3912 |
|
191 |
I |
A |
0.0000 |
|
192 |
H |
A |
-0.1056 |
|
193 |
T |
A |
0.0000 |
|
194 |
D |
A |
-1.4886 |
|
195 |
E |
A |
-2.4726 |
|
196 |
A |
A |
-1.7316 |
|
197 |
D |
A |
-2.7561 |
|
198 |
S |
A |
-1.8316 |
|
199 |
E |
A |
0.0000 |
|
200 |
V |
A |
-0.2234 |
|
201 |
L |
A |
0.0000 |
|
202 |
Y |
A |
0.4024 |
|
203 |
P |
A |
0.0000 |
|
204 |
N |
A |
0.0000 |
|
205 |
Y |
A |
-1.1154 |
|
206 |
Q |
A |
-1.6210 |
|
207 |
S |
A |
-1.3671 |
|
208 |
C |
A |
0.0000 |
|
209 |
W |
A |
-1.0036 |
|
210 |
S |
A |
-1.6668 |
|
211 |
L |
A |
0.0000 |
|
212 |
R |
A |
-2.5366 |
|
213 |
Q |
A |
-3.0194 |
|
214 |
R |
A |
-3.5383 |
|
215 |
T |
A |
0.0000 |
|
216 |
R |
A |
-3.7869 |
|
217 |
G |
A |
-2.7797 |
|
218 |
R |
A |
-2.0462 |
|
219 |
R |
A |
-2.2779 |
|
220 |
Q |
A |
-2.0594 |
|
221 |
T |
A |
-0.7909 |
|
222 |
A |
A |
0.0000 |
|
223 |
S |
A |
-0.1766 |
|
224 |
L |
A |
0.7790 |
|
225 |
Q |
A |
0.0515 |
|
226 |
P |
A |
-0.4757 |
|
227 |
G |
A |
-1.0133 |
|
228 |
I |
A |
0.0000 |
|
229 |
S |
A |
-1.3663 |
|
230 |
E |
A |
-2.7422 |
|
231 |
D |
A |
-2.3394 |
|
232 |
L |
A |
0.0000 |
|
233 |
K |
A |
-3.9959 |
|
234 |
K |
A |
-3.7250 |
|
235 |
V |
A |
0.0000 |
|
236 |
K |
A |
0.0000 |
|
237 |
D |
A |
-4.0935 |
|
238 |
R |
A |
-3.2920 |
|
239 |
M |
A |
-2.0145 |
|
240 |
G |
A |
-2.2307 |
|
241 |
I |
A |
0.0000 |
|
242 |
D |
A |
-3.0465 |
|
243 |
S |
A |
-2.3819 |
|
244 |
S |
A |
-1.7289 |
|
245 |
D |
A |
-2.3326 |
|
246 |
K |
A |
-2.4607 |
|
247 |
V |
A |
0.0000 |
|
248 |
D |
A |
-0.7822 |
|
249 |
F |
A |
0.0000 |
|
250 |
F |
A |
0.5805 |
|
251 |
I |
A |
0.2685 |
|
252 |
L |
A |
0.0000 |
|
253 |
L |
A |
0.0000 |
|
254 |
D |
A |
0.0179 |
|
255 |
N |
A |
0.0000 |
|
256 |
V |
A |
0.0000 |
|
257 |
A |
A |
-0.5113 |
|
258 |
A |
A |
0.0000 |
|
259 |
E |
A |
0.0000 |
|
260 |
Q |
A |
-1.3540 |
|
261 |
A |
A |
-0.6549 |
|
262 |
H |
A |
-0.8519 |
|
263 |
N |
A |
-1.5754 |
|
264 |
L |
A |
-0.9748 |
|
265 |
P |
A |
-0.8640 |
|
266 |
S |
A |
-0.8408 |
|
267 |
C |
A |
-0.3610 |
|
268 |
P |
A |
-0.6116 |
|
269 |
M |
A |
-0.8323 |
|
270 |
L |
A |
0.0000 |
|
271 |
K |
A |
-1.6777 |
|
272 |
R |
A |
-2.1945 |
|
273 |
F |
A |
-1.6109 |
|
274 |
A |
A |
-1.7856 |
|
275 |
R |
A |
-2.6256 |
|
276 |
M |
A |
-1.3503 |
|
277 |
I |
A |
0.0000 |
|
278 |
E |
A |
-1.6946 |
|
279 |
Q |
A |
-1.8469 |
|
280 |
R |
A |
-1.2735 |
|
281 |
A |
A |
0.0000 |
|
282 |
V |
A |
0.0000 |
|
283 |
D |
A |
-0.8589 |
|
284 |
T |
A |
0.0000 |
|
285 |
S |
A |
0.0564 |
|
286 |
L |
A |
-0.1513 |
|
287 |
Y |
A |
0.0316 |
|
288 |
I |
A |
0.0000 |
|
289 |
L |
A |
0.0000 |
|
290 |
P |
A |
-1.0671 |
|
291 |
K |
A |
-1.8062 |
|
292 |
E |
A |
-2.8198 |
|
293 |
D |
A |
-2.7401 |
|
294 |
R |
A |
-2.8779 |
|
295 |
E |
A |
-2.8993 |
|
296 |
S |
A |
0.0000 |
|
297 |
L |
A |
0.0000 |
|
298 |
Q |
A |
-1.0027 |
|
299 |
M |
A |
0.0000 |
|
300 |
A |
A |
0.0000 |
|
301 |
V |
A |
0.0000 |
|
302 |
G |
A |
0.0000 |
|
303 |
P |
A |
0.0000 |
|
304 |
F |
A |
0.0000 |
|
305 |
L |
A |
0.0000 |
|
306 |
H |
A |
-0.2437 |
|
307 |
I |
A |
0.1611 |
|
308 |
L |
A |
0.0000 |
|
309 |
E |
A |
-0.1964 |
|
310 |
S |
A |
-0.0333 |
|
311 |
N |
A |
0.0000 |
|
312 |
L |
A |
0.0000 |
|
313 |
L |
A |
0.3719 |
|
314 |
K |
A |
-0.5977 |
|
315 |
A |
A |
-0.3193 |
|
316 |
M |
A |
0.0982 |
|
317 |
D |
A |
-1.3248 |
|
322 |
P |
A |
-1.8740 |
|
323 |
D |
A |
-2.7253 |
|
324 |
K |
A |
-2.6767 |
|
325 |
I |
A |
-1.5848 |
|
326 |
R |
A |
-1.6494 |
|
327 |
K |
A |
-1.1816 |
|
328 |
L |
A |
0.0000 |
|
329 |
Y |
A |
0.0000 |
|
330 |
L |
A |
0.0000 |
|
331 |
Y |
A |
0.0000 |
|
332 |
A |
A |
0.0000 |
|
333 |
A |
A |
0.0000 |
|
334 |
H |
A |
0.1009 |
|
335 |
D |
A |
0.1735 |
|
336 |
V |
A |
0.7100 |
|
337 |
T |
A |
0.0000 |
|
338 |
F |
A |
0.0000 |
|
339 |
I |
A |
0.0000 |
|
340 |
P |
A |
0.0000 |
|
341 |
L |
A |
0.0000 |
|
342 |
L |
A |
0.0000 |
|
343 |
M |
A |
0.0000 |
|
344 |
T |
A |
0.0000 |
|
345 |
L |
A |
0.0000 |
|
346 |
G |
A |
-0.4912 |
|
347 |
I |
A |
0.0000 |
|
348 |
F |
A |
-0.5729 |
|
349 |
D |
A |
-1.3829 |
|
350 |
H |
A |
-1.6309 |
|
351 |
K |
A |
-2.4528 |
|
352 |
W |
A |
-0.9907 |
|
353 |
P |
A |
0.0000 |
|
354 |
P |
A |
-0.4039 |
|
355 |
F |
A |
0.0797 |
|
356 |
A |
A |
-0.2902 |
|
357 |
V |
A |
0.0000 |
|
358 |
D |
A |
0.0000 |
|
359 |
L |
A |
0.0000 |
|
360 |
T |
A |
0.0000 |
|
361 |
M |
A |
0.0000 |
|
362 |
E |
A |
0.0000 |
|
363 |
L |
A |
0.0000 |
|
364 |
Y |
A |
0.0000 |
|
365 |
Q |
A |
-1.6040 |
|
366 |
H |
A |
-1.9019 |
|
367 |
L |
A |
-1.1326 |
|
368 |
E |
A |
-2.1937 |
|
369 |
S |
A |
-2.0539 |
|
370 |
K |
A |
-2.7995 |
|
371 |
E |
A |
-2.3812 |
|
372 |
W |
A |
-1.2548 |
|
373 |
F |
A |
0.0000 |
|
374 |
V |
A |
0.0000 |
|
375 |
Q |
A |
0.0000 |
|
376 |
L |
A |
0.0000 |
|
377 |
Y |
A |
-1.2715 |
|
378 |
Y |
A |
0.0000 |
|
379 |
H |
A |
-1.9183 |
|
380 |
G |
A |
-2.0768 |
|
381 |
K |
A |
-2.9786 |
|
382 |
E |
A |
-2.4272 |
|
383 |
Q |
A |
-1.1472 |
|
384 |
V |
A |
0.1491 |
|
385 |
P |
A |
0.0000 |
|
386 |
R |
A |
-0.9676 |
|
387 |
G |
A |
-1.0136 |
|
388 |
C |
A |
-0.9220 |
|
389 |
P |
A |
-0.9626 |
|
390 |
D |
A |
-1.5752 |
|
391 |
G |
A |
0.0000 |
|
392 |
L |
A |
-0.3647 |
|
393 |
C |
A |
0.0000 |
|
394 |
P |
A |
-0.8342 |
|
395 |
L |
A |
0.0000 |
|
396 |
D |
A |
-1.9221 |
|
397 |
M |
A |
-1.0050 |
|
398 |
F |
A |
0.0000 |
|
399 |
L |
A |
-0.8762 |
|
400 |
N |
A |
-1.4893 |
|
401 |
A |
A |
-0.8988 |
|
402 |
M |
A |
0.0000 |
|
403 |
S |
A |
-0.3060 |
|
404 |
V |
A |
-0.0642 |
|
405 |
Y |
A |
0.0000 |
|
406 |
T |
A |
-0.3198 |
|
407 |
L |
A |
0.0000 |
|
408 |
S |
A |
-1.3766 |
|
409 |
P |
A |
-1.6934 |
|
410 |
E |
A |
-2.8701 |
|
411 |
K |
A |
-2.5630 |
|
412 |
Y |
A |
-1.6106 |
|
413 |
H |
A |
-2.0333 |
|
414 |
A |
A |
-1.4220 |
|
415 |
L |
A |
-0.8799 |
|
416 |
C |
A |
0.0000 |
|
417 |
S |
A |
-0.7393 |
|
418 |
Q |
A |
-1.3325 |
|
419 |
T |
A |
-0.6198 |
|