Chain sequence(s) |
A: LNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICTDS X: DKESIV C: TMDTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNINESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDT B: YRKDFIDTMTRELYDAFLHERLYLIYMDSRAELKRNSTLKKKFFEKWQAS |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
13 | L | A | -0.5122 | |
14 | N | A | -1.5459 | |
15 | S | A | -1.4734 | |
16 | E | A | -2.0155 | |
17 | L | A | 0.0000 | |
18 | L | A | -1.0116 | |
19 | E | A | -2.5664 | |
20 | E | A | -1.9985 | |
21 | Q | A | -1.3584 | |
22 | K | A | -1.6315 | |
23 | Q | A | -1.7495 | |
24 | E | A | 0.0000 | |
25 | I | A | 0.0000 | |
26 | Y | A | 0.5452 | |
27 | E | A | -0.3918 | |
28 | A | A | 0.0000 | |
29 | F | A | 0.0000 | |
30 | S | A | -0.2076 | |
31 | L | A | -0.0058 | |
32 | F | A | 0.0000 | |
33 | D | A | -1.0550 | |
34 | M | A | -0.4945 | |
35 | N | A | -2.0604 | |
36 | N | A | -2.4628 | |
37 | D | A | -2.6896 | |
38 | G | A | -1.6258 | |
39 | F | A | -1.0268 | |
40 | L | A | 0.0000 | |
41 | D | A | -1.2835 | |
42 | Y | A | -0.8903 | |
43 | H | A | -1.2315 | |
44 | E | A | -0.6518 | |
45 | L | A | 0.0000 | |
46 | K | A | -1.6903 | |
47 | V | A | 0.0000 | |
48 | A | A | 0.0000 | |
49 | M | A | 0.0000 | |
50 | K | A | -1.2673 | |
51 | A | A | 0.0000 | |
52 | L | A | 0.0000 | |
53 | G | A | -0.8662 | |
54 | F | A | -1.0118 | |
55 | E | A | -2.2591 | |
56 | L | A | -1.9257 | |
57 | P | A | -2.6099 | |
58 | K | A | -3.6099 | |
59 | R | A | -3.6681 | |
60 | E | A | -3.6173 | |
61 | I | A | 0.0000 | |
62 | L | A | -2.8360 | |
63 | D | A | -3.8289 | |
64 | L | A | -2.2820 | |
65 | I | A | 0.0000 | |
66 | D | A | -3.8480 | |
67 | E | A | -2.9700 | |
68 | Y | A | -1.8129 | |
69 | D | A | -2.8366 | |
70 | S | A | -2.1772 | |
71 | E | A | -3.0518 | |
72 | G | A | -2.7893 | |
73 | R | A | -3.3117 | |
74 | H | A | -2.2721 | |
75 | L | A | -1.4704 | |
76 | M | A | 0.0000 | |
77 | K | A | -1.2570 | |
78 | Y | A | -0.6817 | |
79 | D | A | -1.5960 | |
80 | D | A | -0.8042 | |
81 | F | A | 0.0000 | |
82 | Y | A | -0.0275 | |
83 | I | A | 0.2795 | |
84 | V | A | 0.0000 | |
85 | M | A | 0.0000 | |
86 | G | A | 0.0000 | |
87 | E | A | -1.4378 | |
88 | K | A | -1.2671 | |
89 | I | A | 0.0000 | |
90 | L | A | -1.2095 | |
91 | K | A | -2.4216 | |
92 | R | A | -2.3386 | |
93 | D | A | -2.8475 | |
94 | P | A | -1.8451 | |
95 | L | A | -1.4282 | |
96 | D | A | -2.8159 | |
97 | E | A | -1.9806 | |
98 | I | A | 0.0000 | |
99 | K | A | -2.3391 | |
100 | R | A | -1.8877 | |
101 | A | A | 0.0000 | |
102 | F | A | 0.0000 | |
103 | Q | A | -2.7129 | |
104 | L | A | -1.6283 | |
105 | F | A | 0.0000 | |
106 | D | A | 0.0000 | |
107 | D | A | -3.4223 | |
108 | D | A | -3.5970 | |
109 | H | A | -2.9247 | |
110 | T | A | -1.9431 | |
111 | G | A | -2.1254 | |
112 | K | A | -2.5897 | |
113 | I | A | 0.0000 | |
114 | S | A | 0.0000 | |
115 | I | A | -1.3624 | |
116 | K | A | -2.3646 | |
117 | N | A | 0.0000 | |
118 | L | A | 0.0000 | |
119 | R | A | -2.9937 | |
120 | R | A | -2.6544 | |
121 | V | A | 0.0000 | |
122 | A | A | 0.0000 | |
123 | K | A | -3.1008 | |
124 | E | A | -2.8997 | |
125 | L | A | -1.9560 | |
126 | G | A | -1.8604 | |
127 | E | A | -1.9751 | |
128 | T | A | -0.8506 | |
129 | L | A | -1.2948 | |
130 | T | A | -1.7486 | |
131 | D | A | -2.6092 | |
132 | E | A | -3.0879 | |
133 | E | A | -2.8452 | |
134 | L | A | 0.0000 | |
135 | R | A | -2.7941 | |
136 | A | A | -2.6271 | |
137 | M | A | 0.0000 | |
138 | I | A | 0.0000 | |
139 | E | A | -3.3267 | |
140 | E | A | -2.5107 | |
141 | F | A | -1.3400 | |
142 | D | A | -1.9383 | |
143 | L | A | -0.7416 | |
144 | D | A | -2.3245 | |
145 | G | A | -2.2457 | |
146 | D | A | -3.0062 | |
147 | G | A | -2.1236 | |
148 | E | A | -2.2010 | |
149 | I | A | 0.0000 | |
150 | N | A | -2.4321 | |
151 | E | A | -2.5037 | |
152 | N | A | -1.9250 | |
153 | E | A | 0.0000 | |
154 | F | A | 0.0000 | |
155 | I | A | -0.9049 | |
156 | A | A | -0.7674 | |
157 | I | A | 0.0000 | |
158 | C | A | 0.0000 | |
159 | T | A | -0.9443 | |
160 | D | A | -1.9934 | |
161 | S | A | -1.2123 | |
756 | Y | B | -0.1236 | |
757 | R | B | -1.5845 | |
758 | K | B | -2.4691 | |
759 | D | B | -2.2626 | |
760 | F | B | -1.3124 | |
761 | I | B | 0.0000 | |
762 | D | B | -2.5024 | |
763 | T | B | -2.1460 | |
764 | M | B | 0.0000 | |
765 | T | B | 0.0000 | |
766 | R | B | -3.3535 | |
767 | E | B | -3.3839 | |
768 | L | B | 0.0000 | |
769 | Y | B | 0.0000 | |
770 | D | B | -2.8565 | |
771 | A | B | -1.8378 | |
772 | F | B | 0.0000 | |
773 | L | B | 0.0000 | |
774 | H | B | -1.2526 | |
775 | E | B | -0.8778 | |
776 | R | B | -0.6099 | |
777 | L | B | 0.0000 | |
778 | Y | B | 0.2563 | |
779 | L | B | 0.2249 | |
780 | I | B | -0.0844 | |
781 | Y | B | 0.0000 | |
782 | M | B | 0.0000 | |
783 | D | B | -0.3733 | |
784 | S | B | 0.0000 | |
785 | R | B | 0.0000 | |
786 | A | B | 0.0000 | |
787 | E | B | -0.8305 | |
788 | L | B | -0.6363 | |
789 | K | B | -0.5946 | |
790 | R | B | -0.5955 | |
791 | N | B | -0.7969 | |
792 | S | B | -0.8237 | |
793 | T | B | 0.0000 | |
794 | L | B | 0.0000 | |
795 | K | B | 0.0000 | |
796 | K | B | -2.0976 | |
797 | K | B | -1.8385 | |
798 | F | B | 0.0000 | |
799 | F | B | 0.0000 | |
800 | E | B | -2.9902 | |
801 | K | B | -2.4772 | |
802 | W | B | 0.0000 | |
803 | Q | B | -1.8622 | |
804 | A | B | -1.2011 | |
805 | S | B | -1.4070 | |
2 | T | C | -1.4528 | |
3 | M | C | -1.9409 | |
4 | D | C | -2.8151 | |
5 | T | C | -1.9072 | |
6 | A | C | -1.2184 | |
7 | Q | C | -1.6954 | |
8 | L | C | 0.0000 | |
9 | K | C | -2.1152 | |
10 | S | C | -1.5450 | |
11 | Q | C | -1.1623 | |
12 | I | C | 0.0000 | |
13 | Q | C | -1.6823 | |
14 | Q | C | -1.6846 | |
15 | Y | C | -0.7915 | |
16 | L | C | 0.0000 | |
17 | V | C | -0.1846 | |
18 | E | C | -1.7534 | |
19 | S | C | -0.9855 | |
20 | G | C | -0.6012 | |
21 | N | C | -0.4268 | |
22 | Y | C | -0.3449 | |
23 | E | C | -1.2352 | |
24 | L | C | -0.3890 | |
25 | I | C | 0.0000 | |
26 | S | C | 0.0000 | |
27 | N | C | -2.0888 | |
28 | E | C | -2.4186 | |
29 | L | C | 0.0000 | |
30 | K | C | -1.4973 | |
31 | A | C | -1.3090 | |
32 | R | C | -1.6251 | |
33 | L | C | 0.0000 | |
34 | L | C | 0.0996 | |
35 | Q | C | -1.0499 | |
36 | E | C | -1.1612 | |
37 | G | C | -1.1573 | |
38 | W | C | 0.0000 | |
39 | V | C | -1.4646 | |
40 | D | C | -2.7891 | |
41 | K | C | -3.0023 | |
42 | V | C | 0.0000 | |
43 | K | C | -2.6628 | |
44 | D | C | -3.3012 | |
45 | L | C | -2.2976 | |
46 | T | C | 0.0000 | |
47 | K | C | -2.1675 | |
48 | S | C | -1.9228 | |
49 | E | C | -2.0344 | |
50 | M | C | 0.0000 | |
51 | N | C | -1.4885 | |
52 | I | C | -0.0944 | |
53 | N | C | -1.9392 | |
54 | E | C | -2.8449 | |
55 | S | C | -1.7520 | |
56 | T | C | -1.3621 | |
57 | N | C | -1.5166 | |
58 | F | C | -0.7421 | |
59 | T | C | -0.6105 | |
60 | Q | C | -1.2126 | |
61 | I | C | -0.6338 | |
62 | L | C | 0.0000 | |
63 | S | C | -0.8632 | |
64 | T | C | -0.9001 | |
65 | V | C | 0.0000 | |
66 | E | C | -1.3232 | |
67 | P | C | -1.5021 | |
68 | K | C | -2.3622 | |
69 | A | C | 0.0000 | |
70 | L | C | -1.6178 | |
71 | E | C | -2.5753 | |
72 | M | C | -1.5992 | |
73 | V | C | 0.0000 | |
74 | S | C | -1.8174 | |
75 | D | C | -2.8586 | |
76 | S | C | -1.9222 | |
77 | T | C | 0.0000 | |
78 | R | C | -2.5285 | |
79 | E | C | -3.0995 | |
80 | T | C | -2.2690 | |
81 | V | C | 0.0000 | |
82 | L | C | -2.4841 | |
83 | K | C | -3.2558 | |
84 | Q | C | -2.5472 | |
85 | I | C | 0.0000 | |
86 | R | C | -3.7468 | |
87 | E | C | -3.6541 | |
88 | F | C | 0.0000 | |
89 | L | C | 0.0000 | |
90 | E | C | -3.0723 | |
91 | E | C | -2.6598 | |
92 | I | C | -1.0155 | |
93 | V | C | 0.0000 | |
94 | D | C | -1.7505 | |
95 | T | C | -0.9733 | |
325 | D | X | -2.9536 | |
326 | K | X | -3.0215 | |
327 | E | X | -2.2161 | |
328 | S | X | -1.2198 | |
329 | I | X | 0.0000 | |
330 | V | X | 1.1596 |