Chain sequence(s) |
A: SSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLTSEELTIAGMTFTTFDLRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID B: SVLQFLGLYKKSGKLVFLGLDNAGKKTTLLHMLKVPTLHPTSEELTIAGMTFTTFDLRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID |
Distance of aggregation | 10 Å |
Dynamic mode | No |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
13 | S | A | -0.4123 | |
14 | S | A | -0.1756 | |
15 | V | A | 0.4098 | |
16 | L | A | 0.0000 | |
17 | Q | A | -0.8660 | |
18 | F | A | 0.1543 | |
19 | L | A | 0.0000 | |
20 | G | A | -0.8691 | |
21 | L | A | 0.0000 | |
22 | Y | A | -0.5649 | |
23 | K | A | -2.0339 | |
24 | K | A | -1.6811 | |
25 | S | A | -1.4174 | |
26 | G | A | -1.3010 | |
27 | K | A | -0.9687 | |
28 | L | A | 0.0000 | |
29 | V | A | 0.0000 | |
30 | F | A | 0.0000 | |
31 | L | A | 0.0000 | |
32 | G | A | 0.0000 | |
33 | L | A | 0.0000 | |
34 | D | A | -2.1483 | |
35 | N | A | -2.1444 | |
36 | A | A | 0.0000 | |
37 | G | A | -0.6171 | |
38 | K | A | 0.0000 | |
39 | T | A | -0.7593 | |
40 | T | A | -0.3233 | |
41 | L | A | 0.0000 | |
42 | L | A | 0.0000 | |
43 | H | A | -0.8772 | |
44 | M | A | -0.5659 | |
45 | L | A | 0.0195 | |
60 | T | A | -0.6150 | |
61 | S | A | 0.0000 | |
62 | E | A | -0.3696 | |
63 | E | A | 0.0000 | |
64 | L | A | 0.0000 | |
65 | T | A | -0.0765 | |
66 | I | A | 0.4184 | |
67 | A | A | -0.1926 | |
68 | G | A | -0.6994 | |
69 | M | A | 0.0000 | |
70 | T | A | -0.3493 | |
71 | F | A | 0.0000 | |
72 | T | A | 0.0000 | |
73 | T | A | 0.0000 | |
74 | F | A | 0.0000 | |
75 | D | A | -2.0121 | |
76 | L | A | -0.9469 | |
84 | R | A | -2.2026 | |
85 | V | A | -0.7160 | |
86 | W | A | 0.0000 | |
87 | K | A | -1.6296 | |
88 | N | A | -1.5056 | |
89 | Y | A | -0.6078 | |
90 | L | A | 0.0000 | |
91 | P | A | -0.5793 | |
92 | A | A | -0.4133 | |
93 | I | A | 0.0000 | |
94 | N | A | -1.2019 | |
95 | G | A | 0.0000 | |
96 | I | A | 0.0000 | |
97 | V | A | 0.0000 | |
98 | F | A | 0.0000 | |
99 | L | A | 0.0000 | |
100 | V | A | 0.0000 | |
101 | D | A | -0.9049 | |
102 | C | A | 0.0000 | |
103 | A | A | -1.6296 | |
104 | D | A | -1.9582 | |
105 | H | A | -1.4451 | |
106 | S | A | -0.7486 | |
107 | R | A | -0.5532 | |
108 | L | A | 0.0000 | |
109 | V | A | 1.4378 | |
110 | E | A | 0.1567 | |
111 | S | A | 0.0000 | |
112 | K | A | 0.4558 | |
113 | V | A | 1.3222 | |
114 | E | A | 0.2137 | |
115 | L | A | 0.0000 | |
116 | N | A | -0.4158 | |
117 | A | A | -0.2437 | |
118 | L | A | 0.0000 | |
119 | M | A | -0.5193 | |
120 | T | A | -0.8193 | |
121 | D | A | -1.2842 | |
122 | E | A | -2.2080 | |
123 | T | A | -1.3612 | |
124 | I | A | 0.0000 | |
125 | S | A | -1.5076 | |
126 | N | A | -1.5758 | |
127 | V | A | -0.8699 | |
128 | P | A | 0.0000 | |
129 | I | A | 0.0000 | |
130 | L | A | 0.0000 | |
131 | I | A | 0.0000 | |
132 | L | A | 0.0000 | |
133 | G | A | 0.0000 | |
134 | N | A | 0.0000 | |
135 | K | A | -0.9216 | |
136 | I | A | -0.5306 | |
137 | D | A | -1.5284 | |
138 | R | A | -2.2563 | |
139 | T | A | -1.6686 | |
140 | D | A | -2.4981 | |
141 | A | A | -1.7657 | |
142 | I | A | 0.0000 | |
143 | S | A | -2.0080 | |
144 | E | A | -2.6782 | |
145 | E | A | -3.4385 | |
146 | K | A | -3.2412 | |
147 | L | A | 0.0000 | |
148 | R | A | -2.2638 | |
149 | E | A | -2.7449 | |
150 | I | A | -1.0182 | |
151 | F | A | 0.0000 | |
152 | G | A | -1.0825 | |
153 | L | A | 0.0000 | |
154 | Y | A | 0.1784 | |
155 | G | A | -0.1806 | |
156 | Q | A | -0.4426 | |
157 | T | A | -0.4641 | |
158 | T | A | -0.6941 | |
159 | G | A | -1.3610 | |
160 | K | A | -2.4315 | |
161 | G | A | -1.9002 | |
162 | N | A | -1.8880 | |
163 | V | A | -1.2793 | |
164 | T | A | -1.1524 | |
165 | L | A | -0.9134 | |
166 | K | A | -2.2848 | |
167 | E | A | -2.6261 | |
168 | L | A | -1.5238 | |
169 | N | A | -1.8253 | |
170 | A | A | -1.1796 | |
171 | R | A | -0.6644 | |
172 | P | A | 0.0000 | |
173 | M | A | 0.0000 | |
174 | E | A | 0.0000 | |
175 | V | A | 0.0000 | |
176 | F | A | -0.4197 | |
177 | M | A | -0.2031 | |
178 | C | A | 0.0000 | |
179 | S | A | 0.0000 | |
180 | V | A | 0.0000 | |
181 | L | A | -0.8701 | |
182 | K | A | -2.6187 | |
183 | R | A | -2.9814 | |
184 | Q | A | -2.6945 | |
185 | G | A | -1.4971 | |
186 | Y | A | 0.0000 | |
187 | G | A | 0.0000 | |
188 | E | A | -1.8911 | |
189 | G | A | 0.0000 | |
190 | F | A | 0.0000 | |
191 | R | A | -1.5816 | |
192 | W | A | 0.0000 | |
193 | L | A | 0.0000 | |
194 | S | A | 0.0000 | |
195 | Q | A | -0.9456 | |
196 | Y | A | -0.5783 | |
197 | I | A | 0.0000 | |
198 | D | A | -2.3373 | |
14 | S | B | 0.0032 | |
15 | V | B | 0.2444 | |
16 | L | B | 0.0000 | |
17 | Q | B | -0.5937 | |
18 | F | B | 0.3478 | |
19 | L | B | 0.0000 | |
20 | G | B | -0.7154 | |
21 | L | B | 0.0000 | |
22 | Y | B | 0.0036 | |
23 | K | B | -1.7260 | |
24 | K | B | -1.5438 | |
25 | S | B | -1.2348 | |
26 | G | B | -1.1865 | |
27 | K | B | -0.7075 | |
28 | L | B | 0.0000 | |
29 | V | B | 0.0000 | |
30 | F | B | 0.0000 | |
31 | L | B | 0.0000 | |
32 | G | B | 0.0000 | |
33 | L | B | 0.0000 | |
34 | D | B | -2.1639 | |
35 | N | B | -2.1510 | |
36 | A | B | 0.0000 | |
37 | G | B | -0.6246 | |
38 | K | B | 0.0000 | |
39 | T | B | -0.3240 | |
40 | T | B | 0.2908 | |
41 | L | B | 0.0000 | |
42 | L | B | 0.0000 | |
43 | H | B | -0.4038 | |
44 | M | B | -0.5525 | |
45 | L | B | 0.0000 | |
46 | K | B | -1.3118 | |
54 | V | B | 1.6449 | |
55 | P | B | 1.0511 | |
56 | T | B | 0.8167 | |
57 | L | B | 1.6242 | |
58 | H | B | 0.5084 | |
59 | P | B | 0.0961 | |
60 | T | B | -0.3433 | |
61 | S | B | -0.2743 | |
62 | E | B | 0.0000 | |
63 | E | B | 0.0000 | |
64 | L | B | 0.0000 | |
65 | T | B | -0.2686 | |
66 | I | B | 0.2345 | |
67 | A | B | -0.0471 | |
68 | G | B | -0.5698 | |
69 | M | B | 0.0000 | |
70 | T | B | -0.2366 | |
71 | F | B | 0.0000 | |
72 | T | B | 0.0000 | |
73 | T | B | 0.0000 | |
74 | F | B | 0.0000 | |
75 | D | B | -1.2647 | |
76 | L | B | -0.4976 | |
84 | R | B | -1.3790 | |
85 | V | B | 0.3853 | |
86 | W | B | -0.3382 | |
87 | K | B | -1.1951 | |
88 | N | B | -1.2229 | |
89 | Y | B | -0.4417 | |
90 | L | B | 0.0000 | |
91 | P | B | -0.5434 | |
92 | A | B | -0.3412 | |
93 | I | B | 0.0000 | |
94 | N | B | -1.0280 | |
95 | G | B | 0.0000 | |
96 | I | B | 0.0000 | |
97 | V | B | 0.0000 | |
98 | F | B | 0.0000 | |
99 | L | B | 0.0000 | |
100 | V | B | 0.0000 | |
101 | D | B | -0.9227 | |
102 | C | B | 0.0000 | |
103 | A | B | -1.7542 | |
104 | D | B | -1.6911 | |
105 | H | B | -1.1921 | |
106 | S | B | -0.6345 | |
107 | R | B | -0.7016 | |
108 | L | B | 0.0000 | |
109 | V | B | 1.4011 | |
110 | E | B | 0.1919 | |
111 | S | B | 0.0000 | |
112 | K | B | 0.4374 | |
113 | V | B | 1.3616 | |
114 | E | B | 0.2603 | |
115 | L | B | 0.0000 | |
116 | N | B | -0.2746 | |
117 | A | B | -0.2168 | |
118 | L | B | 0.0000 | |
119 | M | B | -0.5481 | |
120 | T | B | -0.8113 | |
121 | D | B | -1.2683 | |
122 | E | B | -2.2133 | |
123 | T | B | -1.3815 | |
124 | I | B | 0.0000 | |
125 | S | B | -1.5573 | |
126 | N | B | -1.7354 | |
127 | V | B | 0.0000 | |
128 | P | B | 0.0000 | |
129 | I | B | 0.0000 | |
130 | L | B | 0.0000 | |
131 | I | B | 0.0000 | |
132 | L | B | 0.0000 | |
133 | G | B | 0.0000 | |
134 | N | B | 0.0000 | |
135 | K | B | -1.3300 | |
136 | I | B | -1.2140 | |
137 | D | B | -2.7950 | |
138 | R | B | -3.1120 | |
139 | T | B | -2.1210 | |
140 | D | B | -2.7035 | |
141 | A | B | -1.9979 | |
142 | I | B | 0.0000 | |
143 | S | B | -1.6439 | |
144 | E | B | -1.8762 | |
145 | E | B | -2.9896 | |
146 | K | B | -2.8956 | |
147 | L | B | 0.0000 | |
148 | R | B | -2.0051 | |
149 | E | B | -2.5630 | |
150 | I | B | -0.9725 | |
151 | F | B | 0.0000 | |
152 | G | B | -1.0646 | |
153 | L | B | 0.0000 | |
154 | Y | B | 0.0482 | |
155 | G | B | -0.3615 | |
156 | Q | B | -0.8414 | |
157 | T | B | -0.5722 | |
158 | T | B | -0.7155 | |
159 | G | B | -1.2203 | |
160 | K | B | -2.0500 | |
161 | G | B | -1.7825 | |
162 | N | B | -1.6171 | |
163 | V | B | -0.9538 | |
164 | T | B | -0.7444 | |
165 | L | B | -0.1574 | |
166 | K | B | -1.9665 | |
167 | E | B | -2.2954 | |
168 | L | B | -1.2959 | |
169 | N | B | -1.7279 | |
170 | A | B | -1.1974 | |
171 | R | B | -0.7261 | |
172 | P | B | 0.0000 | |
173 | M | B | 0.0000 | |
174 | E | B | 0.0000 | |
175 | V | B | 0.0000 | |
176 | F | B | 0.0000 | |
177 | M | B | -0.2035 | |
178 | C | B | 0.0000 | |
179 | S | B | 0.0000 | |
180 | V | B | 0.0000 | |
181 | L | B | -0.2948 | |
182 | K | B | -2.4414 | |
183 | R | B | -2.7204 | |
184 | Q | B | -2.7077 | |
185 | G | B | -1.6121 | |
186 | Y | B | 0.0000 | |
187 | G | B | 0.0000 | |
188 | E | B | -1.9985 | |
189 | G | B | 0.0000 | |
190 | F | B | 0.0000 | |
191 | R | B | -1.7776 | |
192 | W | B | 0.0000 | |
193 | L | B | 0.0000 | |
194 | S | B | 0.0000 | |
195 | Q | B | -0.8833 | |
196 | Y | B | -0.4411 | |
197 | I | B | 0.0000 | |
198 | D | B | -2.2090 |