Project name: f80477436141b4f

Chain sequence(s)	A: ETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGAGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNTNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKV
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.4774
• Maximal score value: 2.5549
• Average score: -0.7797
• Total score value: -185.5679

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	E	A	-2.2898
3	T	A	-2.0566
4	N	A	-2.6779
5	N	A	-2.8223
6	E	A	-2.4250
7	C	A	-0.4096
8	S	A	0.5547
9	I	A	1.6032
10	K	A	0.0879
11	V	A	1.3197
12	L	A	0.2314
13	C	A	0.4558
14	R	A	-0.3306
15	F	A	-0.3494
16	R	A	-1.0619
17	P	A	-0.6257
18	L	A	-0.0739
19	N	A	-0.9008
20	Q	A	-0.8107
21	A	A	-0.3342
22	E	A	-0.4829
23	I	A	0.9960
24	L	A	0.9151
25	R	A	-1.3733
26	G	A	-0.8416
27	D	A	-0.9985
28	K	A	-1.1320
29	F	A	1.0932
30	I	A	2.1823
31	P	A	1.8454
32	I	A	2.1238
33	F	A	0.4900
34	Q	A	-1.1506
35	G	A	-1.8648
36	D	A	-2.6636
37	D	A	-1.6940
38	S	A	-0.2654
39	V	A	0.0000
40	V	A	0.8791
41	I	A	1.1496
42	G	A	0.2467
43	A	A	-0.5269
44	G	A	-0.9530
45	K	A	-1.5068
46	P	A	-0.1786
47	Y	A	0.9218
48	V	A	1.2086
49	F	A	0.3579
50	D	A	-1.3451
51	R	A	-1.4263
52	V	A	0.0000
53	F	A	0.0000
54	P	A	-0.6351
55	P	A	-0.9269
56	N	A	-1.5252
57	T	A	-1.1575
58	T	A	-0.9719
59	Q	A	0.0000
60	E	A	-1.4102
61	Q	A	-1.7272
62	V	A	0.0000
63	Y	A	0.0000
64	H	A	-1.5604
65	A	A	-1.1596
66	C	A	-0.6464
67	A	A	0.0000
68	M	A	-1.0596
69	Q	A	-1.4894
70	I	A	-0.6567
71	V	A	0.0000
72	K	A	-1.3822
73	D	A	-0.8920
74	V	A	0.0000
75	L	A	0.0000
76	A	A	-0.1073
77	G	A	-0.3028
78	Y	A	0.3890
79	N	A	-0.8402
80	G	A	-0.5525
81	T	A	0.7357
82	I	A	1.6205
83	F	A	2.5549
84	A	A	1.5966
85	Y	A	1.5119
86	G	A	-0.3153
87	Q	A	-1.6284
88	T	A	-1.2483
89	S	A	-0.9399
90	S	A	-0.8287
91	G	A	-0.8649
92	K	A	-0.3988
93	T	A	-0.8599
94	H	A	-1.5322
95	T	A	-0.7564
96	M	A	0.0000
97	E	A	-1.0636
98	G	A	-1.5681
99	K	A	-2.1807
100	L	A	-1.5389
101	H	A	-1.9735
102	D	A	-1.6612
103	P	A	-1.4167
104	Q	A	-1.6272
105	L	A	-1.1460
106	M	A	-1.4028
107	G	A	0.0000
108	I	A	0.0000
109	I	A	0.0000
110	P	A	0.0000
111	R	A	-1.1753
112	I	A	0.0000
113	A	A	0.0000
114	R	A	-2.6837
115	D	A	-1.6690
116	I	A	0.0000
117	F	A	0.0000
118	N	A	-1.4440
119	H	A	-0.7639
120	I	A	-0.1858
121	Y	A	0.4430
122	S	A	-0.3468
123	M	A	-0.9000
124	D	A	-2.6830
125	E	A	-3.0088
126	N	A	-2.8045
127	L	A	-2.8868
128	E	A	-2.8371
129	F	A	-1.5621
130	H	A	-1.3241
131	I	A	0.0000
132	K	A	-0.6293
133	V	A	0.0000
134	S	A	0.0000
135	Y	A	0.0000
136	F	A	0.0000
137	E	A	0.0000
138	I	A	-0.4925
139	Y	A	-0.3271
140	L	A	0.2208
141	D	A	-1.8382
142	K	A	-2.3061
143	I	A	0.0000
144	R	A	-1.3140
145	D	A	0.0000
146	L	A	0.0000
147	L	A	0.0000
148	D	A	-1.1317
149	V	A	-0.5342
150	T	A	-0.6324
151	K	A	-1.4124
152	T	A	-1.4836
153	N	A	-2.0679
154	L	A	-1.0959
155	S	A	-0.3527
156	V	A	0.6105
157	H	A	-1.3001
158	E	A	-3.0756
159	D	A	-2.8810
160	K	A	-3.3479
161	N	A	-3.1988
162	R	A	-3.4774
163	V	A	-1.5299
164	P	A	-1.2495
165	F	A	-0.2860
166	V	A	-0.1269
167	K	A	-1.2493
168	G	A	-1.1598
169	C	A	-1.1773
170	T	A	-1.5357
171	E	A	-1.7582
172	R	A	-0.7307
173	F	A	0.6712
174	V	A	0.0000
175	S	A	-0.5224
176	S	A	-1.3274
177	P	A	0.0000
178	E	A	-3.2214
179	E	A	-2.3779
180	I	A	0.0000
181	L	A	0.0000
182	D	A	-3.0685
183	V	A	0.0000
184	I	A	0.0000
185	D	A	-2.0480
186	E	A	-1.9212
187	G	A	0.0000
188	K	A	-1.9900
189	S	A	-1.2676
190	N	A	-0.8876
191	R	A	-0.8456
192	H	A	-0.7927
193	V	A	0.9009
194	A	A	0.4788
195	V	A	-0.3458
196	T	A	-0.8234
197	N	A	-2.2229
198	T	A	-1.8887
199	N	A	-2.5130
200	E	A	-2.6721
201	H	A	0.0000
202	S	A	-1.5912
203	S	A	-1.5720
204	R	A	-1.1125
205	S	A	0.0000
206	H	A	-0.0336
207	S	A	-0.0252
208	I	A	0.0000
209	F	A	0.0000
210	L	A	-0.1146
211	I	A	0.0000
212	N	A	-0.9292
213	I	A	0.0000
214	K	A	-1.8765
215	Q	A	0.0000
216	E	A	-3.3854
217	N	A	-3.1715
218	M	A	-2.1668
219	E	A	-2.6463
220	T	A	-2.4336
221	E	A	-3.4185
222	Q	A	-3.2940
223	K	A	-3.2431
224	L	A	-1.0563
225	S	A	-0.9334
226	G	A	0.0000
227	K	A	-0.7477
228	L	A	0.0000
229	Y	A	0.4040
230	L	A	0.0000
231	V	A	1.1686
232	D	A	0.5816
233	L	A	0.5804
234	A	A	-0.3984
235	G	A	-1.0779
236	S	A	-0.9138
237	E	A	-1.6867
238	K	A	-1.3833
239	V	A	0.7526