Project name: fa8809ff5b47e65

Status: done

submitted: 2018-03-09 12:47:06, status changed: 2018-03-09 13:37:42
Settings
Chain sequence(s) A: PVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLMPVLKETEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVQNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
Distance of aggregation 10 Å
Dynamic mode No
Show buried residues

Minimal score value
-3.6038
Maximal score value
2.2228
Average score
-0.8697
Total score value
-349.6274

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index residue name chain Aggrescan3D score mutation
residue index residue name chain Aggrescan3D score
mutation
14 P A -0.4920
15 V A 0.2451
16 W A 0.0000
17 K A -0.9217
18 S A -0.5902
19 Y A -0.2176
20 L A 0.0000
21 Y A -0.6920
22 Q A -1.6179
23 L A 0.0000
24 Q A -1.1104
25 Q A -2.2869
26 E A -2.0138
27 A A -1.2493
28 P A -1.3782
29 H A -1.9597
30 P A -1.7981
31 R A -2.1399
32 R A -2.1018
33 I A -0.6592
34 T A -0.8882
35 C A -0.6200
36 T A -0.4042
37 C A -0.6440
38 E A -2.2879
39 V A -2.0647
40 E A -2.9506
41 N A -3.0826
42 R A -2.8820
43 P A -1.7863
44 K A -1.9897
45 Y A -0.7153
46 Y A 0.0000
47 G A -1.5736
48 R A -2.1494
49 E A 0.0000
50 F A 0.0000
51 H A -0.5048
52 G A 0.0000
53 M A -0.0369
54 I A -0.4958
55 S A -1.8115
56 R A -3.1905
57 E A -3.0883
58 A A -1.8068
59 A A 0.0000
60 D A -1.5584
61 Q A -0.9822
62 L A 0.4257
63 L A 0.0000
64 I A 1.9554
65 V A 2.2228
66 A A 0.7428
67 E A -0.9568
68 G A 0.0000
69 S A 0.0000
70 Y A 0.0000
71 L A 0.0000
72 I A 0.0000
73 R A -0.6525
74 E A -1.2804
75 S A -2.2203
76 Q A -2.7755
77 R A -3.1762
78 Q A -2.7458
79 P A -1.8987
80 G A -1.3667
81 T A -1.3160
82 Y A -0.6830
83 T A 0.0000
84 L A 0.0000
85 A A 0.0000
86 L A 0.0000
87 R A -0.8615
88 F A 0.0000
89 G A -1.0152
90 S A -0.7205
91 Q A -1.6318
92 T A -1.7502
93 R A -1.8463
94 N A -2.2694
95 F A -1.1030
96 R A -1.6429
97 L A 0.0000
98 Y A -0.0656
99 Y A -0.5278
100 D A -2.0963
101 G A -1.9050
102 K A -2.6807
103 H A 0.0000
104 F A -1.4235
105 V A -0.4006
106 G A -1.4786
107 E A -2.2501
108 K A -1.8263
109 R A -3.1554
110 F A 0.0000
111 E A -2.8297
112 S A -1.7299
113 I A 0.0000
114 H A -1.5423
115 D A -1.3304
116 L A 0.0000
117 V A 0.0000
118 T A -0.6878
119 D A 0.0000
120 G A -0.0928
121 L A 0.0000
122 I A 0.0000
123 T A -0.5935
124 L A -0.7725
125 Y A -1.0043
126 I A 0.0000
127 E A -2.3626
128 T A -1.8855
129 K A -2.3668
130 A A 0.0000
131 A A -1.9988
132 E A -2.5227
133 Y A -1.5179
134 I A -1.2869
135 A A -1.2013
136 K A -1.5754
137 M A 0.0000
138 T A 0.1068
139 I A 0.8520
140 N A -0.6732
141 P A -0.3642
142 I A -0.4503
143 Y A -1.3471
144 E A -2.6383
145 H A -2.3121
146 V A -0.9138
147 G A -0.6886
148 Y A -0.4721
149 T A -0.4173
150 T A 0.4699
151 L A 1.5405
161 M A 0.1437
162 P A -0.1833
163 V A 0.0000
164 L A -1.5870
165 K A -3.0719
166 E A -2.8832
167 T A -1.5123
203 E A -2.4285
204 K A -1.6777
205 I A 0.1760
206 H A 0.0000
207 N A -1.1923
208 F A -0.7343
209 K A -0.7508
210 V A 0.6332
211 H A -0.0900
212 T A -0.1776
213 F A 0.0000
214 R A -1.9187
215 G A -1.3107
216 P A -0.5903
217 H A -0.6381
218 W A 0.0000
219 C A 0.0000
220 E A -0.3877
221 Y A 0.0000
222 C A 0.0000
223 A A 0.0000
224 N A 0.0000
225 F A 0.0000
226 M A 0.0000
227 W A 0.0630
228 G A 0.0000
229 L A 0.2951
230 I A 0.0696
231 A A -0.2527
232 Q A 0.0581
233 G A 0.0000
234 V A 0.0000
235 K A -0.6853
236 C A 0.0000
237 A A -0.9404
238 D A -1.4764
239 C A 0.0000
240 G A -1.5081
241 L A -0.5620
242 N A -0.4848
243 V A 0.0000
244 H A 0.0000
245 K A -2.0780
246 Q A -1.9092
247 C A 0.0000
248 S A -1.8775
249 K A -2.2036
250 M A -1.0655
251 V A 0.0000
252 Q A -2.0298
253 N A -1.8244
254 D A -1.7627
255 C A 0.0000
256 K A -1.6072
257 P A -2.1419
258 D A -2.7361
259 L A -2.3742
260 K A -3.2036
261 H A -2.9862
262 V A -2.5844
263 K A -2.9090
264 K A -2.0893
265 V A 0.0000
266 Y A 0.0000
267 S A -0.1875
268 C A -0.0978
269 D A 0.0000
270 L A 0.0000
271 T A -0.6368
272 T A -0.9038
273 L A 0.0000
274 V A -1.1591
275 K A -1.8775
276 A A -1.0193
277 H A -0.9525
278 T A -1.1402
279 T A -1.3052
280 K A -2.3524
281 R A -1.5618
282 P A 0.0000
283 M A 0.0000
284 V A 0.0000
285 V A 0.0000
286 D A -1.3775
287 M A -1.2248
288 C A 0.0000
289 I A 0.0000
290 R A -2.4204
291 E A -1.3365
292 I A 0.0000
293 E A -2.0732
294 S A -1.3021
295 R A -0.9678
296 G A -1.3096
297 L A 0.0000
298 N A -2.7473
299 S A -1.9488
300 E A -2.7222
301 G A -1.4194
302 L A 0.0000
303 Y A 0.0000
304 R A -1.5304
305 V A -0.1415
306 S A 0.1323
307 G A 0.4590
308 F A 1.0819
309 S A -0.2836
310 D A -1.6081
311 L A -0.3515
312 I A 0.0000
313 E A -1.1852
314 D A -1.0308
315 V A 0.0000
316 K A -0.8615
317 M A -0.9402
318 A A 0.0000
319 F A 0.0000
320 D A 0.0000
321 R A -2.9273
322 D A -2.7492
323 G A -2.6189
324 E A -3.1778
325 K A -3.3185
326 A A 0.0000
327 D A -1.9746
328 I A 0.0000
329 S A -0.3745
330 V A 0.0738
331 N A -0.9234
332 M A -0.2739
333 Y A 0.0000
334 E A -1.7291
335 D A -1.0792
336 I A -0.5253
337 N A -0.5026
338 I A 0.0000
339 I A 0.0000
340 T A 0.0000
341 G A -0.0029
342 A A 0.0000
343 L A 0.0000
344 K A -0.3269
345 L A -0.3311
346 Y A 0.0000
347 F A 0.0000
348 R A -1.0152
349 D A 0.0000
350 L A 0.0000
351 P A 0.0000
352 I A 0.0000
353 P A 0.0000
354 L A 0.0000
355 I A 0.0000
356 T A 0.0000
357 Y A 0.0000
358 D A -1.9654
359 A A 0.0000
360 Y A 0.0000
361 P A -1.3606
362 K A -1.7794
363 F A 0.0000
364 I A 0.0000
365 E A -2.3949
366 S A 0.0000
367 A A 0.0000
368 K A -1.7497
369 I A -0.8960
370 M A -0.0828
371 D A -1.7786
372 P A -1.8437
373 D A -3.1721
374 E A -3.2213
375 Q A -2.6518
376 L A -2.1787
377 E A -3.6038
378 T A 0.0000
379 L A 0.0000
380 H A -2.1421
381 E A -2.7895
382 A A 0.0000
383 L A 0.0000
384 K A -1.9342
385 L A -0.7875
386 L A 0.0000
387 P A -0.5668
388 P A -0.8166
389 A A 0.0000
390 H A 0.0000
391 C A -0.8831
392 E A -1.7262
393 T A 0.0000
394 L A 0.0000
395 R A -1.5445
396 Y A -0.7535
397 L A 0.0000
398 M A 0.0000
399 A A -1.1915
400 H A 0.0000
401 L A 0.0000
402 K A -1.4543
403 R A -1.4079
404 V A 0.0000
405 T A -1.2863
406 L A -0.2596
407 H A -1.9505
408 E A -2.7192
409 K A -3.1030
410 E A -3.3049
411 N A 0.0000
412 L A -0.8170
413 M A 0.0000
414 N A -1.1470
415 A A -1.3991
416 E A -1.6165
417 N A -0.9449
418 L A 0.0000
419 G A 0.0000
420 I A -0.6662
421 V A -0.3732
422 F A 0.0000
423 G A 0.0000
424 P A -0.4457
425 T A 0.0000
426 L A 0.0000
427 M A 0.0000
428 R A -0.9918
429 S A -1.0363
430 P A -1.4425
431 E A -1.5746
432 L A 0.0718
433 D A -0.8229
434 A A -0.0779
435 M A 0.8418
436 A A 0.0178
437 A A -0.1781
438 L A 0.4865
439 N A -0.8787
440 D A -1.0880
441 I A -0.8505
442 R A -1.8764
443 Y A -1.5990
444 Q A 0.0000
445 R A -1.2698
446 L A -0.8840
447 V A 0.0000
448 V A 0.0000
449 E A -1.1485
450 L A 0.0000
451 L A 0.0000
452 I A 0.0000
453 K A -1.9570
454 N A -1.0231
455 E A -1.1272
456 D A -1.2694
457 I A 1.0160
458 L A 0.0000
459 F A 0.2938

 

Laboratory of Theory of Biopolymers 2015