Project name: 10%_ap_2osl

Chain sequence(s)	A: QIVLSQSPAILSASPGEKVTMTCRASSSVSYIHWFQQKPGSSPKPWIYATSNLASGVPVRFSGSGSGTSYSLTISRVEAEDAATYYCQQWTSNPPTFGGGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECQVQLQQPGAELVKPGASVKMSCKASGYTFTSYNMHWVKQTPGRGLEWIGAIYPGNGDTSYNQKFKGKATLTADKSSSTAYMQLSSLTSEDSAVYYCARSTYYGGDWYFNVWGAGTTVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.7195
• Maximal score value: 1.7475
• Average score: -0.6533
• Total score value: -284.2063

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.0205
2	I	A	-0.0187
3	V	A	1.0894
4	L	A	0.0000
5	S	A	-0.6360
6	Q	A	-0.7384
7	S	A	-0.5053
8	P	A	0.1166
9	A	A	0.2834
10	I	A	1.1922
11	L	A	0.5667
12	S	A	-0.3444
13	A	A	0.0000
14	S	A	-1.9148
15	P	A	-2.0266
16	G	A	-2.2301
17	E	A	-2.9883
18	K	A	-2.9582
19	V	A	0.0000
20	T	A	-0.4342
21	M	A	0.0000
22	T	A	-0.7082
23	C	A	0.0000
24	R	A	-1.8933
25	A	A	0.0000
26	S	A	-0.3179
27	S	A	-0.5152
28	S	A	-0.6619
29	V	A	0.0000
30	S	A	-0.1857
31	Y	A	0.1546
32	I	A	0.0000
33	H	A	0.0000
34	W	A	0.0000
35	F	A	0.0000
36	Q	A	0.0000
37	Q	A	-0.7869
38	K	A	0.0000
39	P	A	-0.8638
40	G	A	-0.6247
41	S	A	-0.6833
42	S	A	-0.5084
43	P	A	0.0000
44	K	A	-1.3904
45	P	A	-0.6819
46	W	A	0.0000
47	I	A	0.0000
48	Y	A	-0.0110
49	A	A	-0.1417
50	T	A	-0.2534
51	S	A	-0.5685
52	N	A	-0.8887
53	L	A	0.0772
54	A	A	0.0000
55	S	A	-0.4661
56	G	A	-0.2227
57	V	A	0.0000
58	P	A	0.5742
59	V	A	1.2999
60	R	A	-0.5402
61	F	A	0.0000
62	S	A	-0.0608
63	G	A	-0.4627
64	S	A	-0.5909
65	G	A	-0.7314
66	S	A	-0.6749
67	G	A	-0.6724
68	T	A	-0.9872
69	S	A	-1.0320
70	Y	A	0.0000
71	S	A	-0.6120
72	L	A	0.0000
73	T	A	-0.7741
74	I	A	0.0000
75	S	A	-2.0496
76	R	A	-3.1641
77	V	A	0.0000
78	E	A	-2.9633
79	A	A	0.0000
80	E	A	-2.7769
81	D	A	0.0000
82	A	A	-1.7958
83	A	A	0.0000
84	T	A	-0.5128
85	Y	A	0.0000
86	Y	A	-0.3224
87	C	A	0.0000
88	Q	A	0.0000
89	Q	A	0.0000
90	W	A	-0.0536
91	T	A	-0.3987
92	S	A	-0.9557
93	N	A	-1.6648
94	P	A	-1.5161
95	P	A	0.0000
96	T	A	0.0000
97	F	A	0.1908
98	G	A	0.0000
99	G	A	-0.8542
100	G	A	-0.4673
101	T	A	0.0000
102	K	A	-0.8374
103	L	A	0.0000
104	E	A	-1.1649
105	I	A	0.0000
106	K	A	-1.4046
107	R	A	-1.0053
108	T	A	0.1186
109	V	A	0.9140
110	A	A	0.0939
111	A	A	-0.0497
112	P	A	0.0000
113	S	A	-0.2248
114	V	A	0.0000
115	F	A	0.0286
116	I	A	0.0000
117	F	A	0.0000
118	P	A	-0.5058
119	P	A	-0.7677
120	S	A	-1.4832
121	D	A	-2.7176
122	E	A	-2.6010
123	Q	A	0.0000
124	L	A	-1.5188
125	K	A	-1.9627
126	S	A	-1.3541
127	G	A	-0.9780
128	T	A	-0.8810
129	A	A	0.0000
130	S	A	0.0000
131	V	A	0.0000
132	V	A	0.0000
133	C	A	0.0000
134	L	A	0.0000
135	L	A	0.0000
136	N	A	0.0000
137	N	A	-0.9353
138	F	A	0.0000
139	Y	A	0.0000
140	P	A	-1.7584
141	R	A	-3.2467
142	E	A	-3.2603
143	A	A	-2.4139
144	K	A	-2.4273
145	V	A	0.0000
146	Q	A	-0.6319
147	W	A	0.0000
148	K	A	-0.7900
149	V	A	0.0000
150	D	A	-2.5939
151	N	A	-1.8464
152	A	A	-0.4225
153	L	A	0.7965
154	Q	A	0.0980
155	S	A	-0.2895
156	G	A	-0.9075
157	N	A	-0.7061
158	S	A	-0.8064
159	Q	A	-1.7917
160	E	A	-2.1479
161	S	A	-1.2372
162	V	A	-0.9650
163	T	A	-1.0788
164	E	A	-2.3525
165	Q	A	-2.2068
166	D	A	-2.4411
167	S	A	-2.6236
168	K	A	-2.7843
169	D	A	-1.8111
170	S	A	0.0000
171	T	A	0.0000
172	Y	A	-1.3021
173	S	A	0.0000
174	L	A	0.0000
175	S	A	0.0000
176	S	A	0.0000
177	T	A	-0.1026
178	L	A	0.8397
179	T	A	0.2812
180	L	A	-0.2886
181	S	A	-1.0816
182	K	A	-1.9566
183	A	A	-1.8327
184	D	A	-2.4406
185	Y	A	0.0000
186	E	A	-3.6862
187	K	A	-3.7195
188	H	A	-3.2219
189	K	A	-3.5996
190	V	A	0.0000
191	Y	A	0.0000
192	A	A	0.0000
193	C	A	0.0000
194	E	A	-0.9732
195	V	A	0.0000
196	T	A	-1.3114
197	H	A	0.0000
198	Q	A	-1.5018
199	G	A	-0.2994
200	L	A	-0.1529
201	S	A	-0.3905
202	S	A	-0.4073
203	P	A	-0.5792
204	V	A	0.0645
205	T	A	-0.3376
206	K	A	-0.4279
207	S	A	-0.4591
208	F	A	-0.9606
209	N	A	-2.0503
210	R	A	-2.6129
211	G	A	-2.3272
212	E	A	-2.5049
1	Q	A	-0.9065
2	V	A	0.1772
3	Q	A	-0.9250
4	L	A	0.0000
5	Q	A	-1.6203
6	Q	A	-0.9509
7	P	A	-0.7659
8	G	A	-0.8942
9	A	A	-0.7385
10	E	A	-0.5754
11	L	A	-0.2597
12	V	A	0.0000
13	K	A	-1.8385
14	P	A	-1.2195
15	G	A	-1.1287
16	A	A	-0.9918
17	S	A	-1.0471
18	V	A	-0.9317
19	K	A	-1.4077
20	M	A	0.0000
21	S	A	-0.7515
22	C	A	0.0000
23	K	A	-1.6041
24	A	A	0.0000
25	S	A	-0.7434
26	G	A	-0.4458
27	Y	A	-0.0349
28	T	A	-0.1020
29	F	A	0.0000
30	T	A	-0.7234
31	S	A	-0.0824
32	Y	A	0.3324
33	N	A	-0.2140
34	M	A	0.0000
35	H	A	0.0000
36	W	A	0.0000
37	V	A	0.0000
38	K	A	0.0000
39	Q	A	-0.5476
40	T	A	-1.1042
41	P	A	-1.0330
42	G	A	-1.5933
43	R	A	-2.3713
44	G	A	-1.4583
45	L	A	0.0000
46	E	A	-1.0205
47	W	A	0.0000
48	I	A	0.0000
49	G	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	Y	A	-0.6549
53	P	A	0.0000
54	G	A	-1.3946
55	N	A	-1.9286
56	G	A	-1.8688
57	D	A	-2.3021
58	T	A	-1.0963
59	S	A	-0.8932
60	Y	A	-1.0751
61	N	A	0.0000
62	Q	A	-2.7653
63	K	A	-2.8817
64	F	A	0.0000
65	K	A	-2.7791
66	G	A	-1.8692
67	K	A	-1.6384
68	A	A	0.0000
69	T	A	-0.7665
70	L	A	0.0000
71	T	A	-0.4601
72	A	A	-1.2184
73	D	A	-1.8145
74	K	A	-2.2598
75	S	A	-1.3265
76	S	A	-1.1797
77	S	A	-1.3376
78	T	A	0.0000
79	A	A	0.0000
80	Y	A	-0.4154
81	M	A	0.0000
82	Q	A	-1.1895
83	L	A	0.0000
84	S	A	-0.8330
85	S	A	-0.8036
86	L	A	0.0000
87	T	A	-1.2647
88	S	A	-1.3429
89	E	A	-1.9633
90	D	A	0.0000
91	S	A	-0.5915
92	A	A	0.0000
93	V	A	0.3512
94	Y	A	0.0000
95	Y	A	0.0000
96	C	A	0.0000
97	A	A	0.0000
98	R	A	0.0000
99	S	A	0.0000
100	T	A	0.0000
101	Y	A	1.7475
102	Y	A	1.6160
103	G	A	0.3570
104	G	A	0.0490
105	D	A	0.4906
106	W	A	0.9516
107	Y	A	0.0000
108	F	A	0.0000
109	N	A	-0.3154
110	V	A	-0.1433
111	W	A	0.0000
112	G	A	0.0000
113	A	A	-0.4690
114	G	A	-0.3157
115	T	A	0.0000
116	T	A	-0.1400
117	V	A	0.0000
118	T	A	-0.6014
119	V	A	0.0000
120	S	A	-0.6165
121	A	A	-0.5450
122	A	A	-0.3742
123	S	A	-0.5991
124	T	A	-0.9403
125	K	A	-1.1985
126	G	A	-1.4079
127	P	A	-0.6574
128	S	A	-0.5578
129	V	A	0.0000
130	F	A	0.0000
131	P	A	-1.2434
132	L	A	0.0000
133	A	A	-1.2265
134	P	A	0.0000
135	S	A	-1.2258
136	S	A	-1.0570
137	K	A	-0.9209
138	S	A	-0.6039
139	T	A	-0.6714
140	S	A	-0.8066
141	G	A	-1.0050
142	G	A	-0.9057
143	T	A	-0.6354
144	A	A	0.0000
145	A	A	0.0000
146	L	A	0.0000
147	G	A	0.0000
148	C	A	0.0000
149	L	A	0.0000
150	V	A	0.0000
151	K	A	-0.1821
152	D	A	-0.6685
153	Y	A	0.0000
154	F	A	-0.4009
155	P	A	0.0000
156	E	A	-1.0601
157	P	A	-1.0416
158	V	A	-0.4857
159	T	A	-0.5526
160	V	A	0.0573
161	S	A	-0.3607
162	W	A	0.0000
163	N	A	-0.8467
164	S	A	-0.6771
165	G	A	-0.5333
166	A	A	-0.2411
167	L	A	-0.0080
168	T	A	-0.1723
169	S	A	-0.2022
170	G	A	-0.2501
171	V	A	0.1789
172	H	A	-0.0846
173	T	A	-0.1757
174	F	A	0.0000
175	P	A	-0.2871
176	A	A	0.4004
177	V	A	0.6612
178	L	A	1.3146
179	Q	A	0.1923
180	S	A	-0.0789
181	S	A	-0.2939
182	G	A	-0.0198
183	L	A	0.0631
184	Y	A	0.3553
185	S	A	0.2654
186	L	A	0.3291
187	S	A	0.0000
188	S	A	0.0000
189	V	A	0.0000
190	V	A	0.0000
191	T	A	-0.1684
192	V	A	0.0000
193	P	A	-0.5025
194	S	A	-0.6449
195	S	A	-0.6311
196	S	A	-0.5607
197	L	A	-0.6803
198	G	A	-0.7113
199	T	A	-0.7199
200	Q	A	-1.0310
201	T	A	-1.1465
202	Y	A	0.0000
203	I	A	-1.4315
204	C	A	0.0000
205	N	A	-1.6244
206	V	A	0.0000
207	N	A	-1.7843
208	H	A	0.0000
209	K	A	-2.8292
210	P	A	-1.6609
211	S	A	-1.8165
212	N	A	-2.6474
213	T	A	-2.0799
214	K	A	-2.7755
215	V	A	-1.8281
216	D	A	-2.7537
217	K	A	-2.5099
218	K	A	-2.7196
219	V	A	0.0000
220	E	A	-2.7210
221	P	A	-2.0906
222	K	A	-2.3857
223	S	A	-1.3861