Project name: 4XJV

Chain sequence(s)	A: ATFKLICFPWMGGGSTHFAKWGQDTHDLLEVHSLQLVDEVVCALQPVIQDKPFAFFGHSMGSYIAFRTALGLKENNQPEPLHLFLSSATPVHSKAWHRIPKDDELSEEQISHYLMEFAEAKEFVKQCSPIIRADLNIVRSCTSNVPSKAVLSCDLTCFVGSEDIAKDMEAWKDVTSGNAKIYQLPGGHFYLLDPANEKLIKNYIIKCLEVSSISNF
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -3.5653
• Maximal score value: 2.0849
• Average score: -0.7232
• Total score value: -156.2064

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
25	A	A	-0.3722
26	T	A	-0.3413
27	F	A	0.0000
28	K	A	0.0000
29	L	A	0.0000
30	I	A	0.0000
31	C	A	0.0000
32	F	A	0.0000
33	P	A	0.0000
34	W	A	0.0000
35	M	A	0.3123
36	G	A	-0.0783
37	G	A	-0.5496
38	G	A	-0.5373
39	S	A	-0.4143
40	T	A	-0.5818
41	H	A	-0.7153
42	F	A	0.0000
43	A	A	0.0406
44	K	A	-0.0366
45	W	A	0.3744
46	G	A	-0.9752
47	Q	A	-2.2070
48	D	A	-2.4166
49	T	A	-1.1918
50	H	A	-0.8965
51	D	A	-0.2322
52	L	A	0.6498
53	L	A	0.4922
54	E	A	-0.2666
55	V	A	-0.1153
56	H	A	-0.0095
57	S	A	0.2761
58	L	A	1.5723
77	Q	A	-1.4591
78	L	A	-0.7419
79	V	A	-0.9012
80	D	A	-1.9726
81	E	A	-2.0104
82	V	A	-0.8849
83	V	A	0.0000
84	C	A	-0.1497
85	A	A	-0.3127
86	L	A	0.0000
87	Q	A	-0.9011
88	P	A	-0.7150
89	V	A	-0.5061
90	I	A	-1.2870
91	Q	A	-2.4158
92	D	A	-2.9037
93	K	A	-2.2142
94	P	A	-1.1666
95	F	A	0.0000
96	A	A	0.0000
97	F	A	0.0000
98	F	A	0.0000
99	G	A	0.0000
100	H	A	0.0000
101	S	A	0.2154
102	M	A	0.0000
103	G	A	0.0000
104	S	A	0.0000
105	Y	A	0.0000
106	I	A	0.0000
107	A	A	0.0000
108	F	A	0.0000
109	R	A	-0.2256
110	T	A	0.0000
111	A	A	0.0000
112	L	A	0.0000
113	G	A	-1.8415
114	L	A	0.0000
115	K	A	-2.9312
116	E	A	-3.4080
117	N	A	-3.3835
118	N	A	-3.1183
119	Q	A	-2.3919
120	P	A	-1.4622
121	E	A	-1.1510
122	P	A	0.0000
123	L	A	0.0542
124	H	A	0.0000
125	L	A	0.0000
126	F	A	0.0000
127	L	A	0.0000
128	S	A	0.0000
129	S	A	0.0000
130	A	A	0.0000
131	T	A	-0.8951
132	P	A	0.0000
133	V	A	-1.0268
134	H	A	-1.5860
135	S	A	-2.0055
136	K	A	-2.2047
137	A	A	-1.5137
138	W	A	-1.6370
139	H	A	-2.0651
140	R	A	-2.4157
141	I	A	-1.7709
142	P	A	-2.4376
143	K	A	-3.5588
144	D	A	-3.1362
145	D	A	-3.5608
146	E	A	-3.5653
147	L	A	0.0000
148	S	A	-1.9748
149	E	A	-2.0585
150	E	A	-2.9746
151	Q	A	-2.2457
152	I	A	0.0000
153	S	A	-1.6324
154	H	A	-1.4375
155	Y	A	-0.5222
156	L	A	0.1109
157	M	A	0.7482
158	E	A	0.1958
166	F	A	1.2708
167	A	A	-0.2102
168	E	A	-1.6168
169	A	A	-1.1565
170	K	A	-2.7350
171	E	A	-2.5775
172	F	A	-0.5952
173	V	A	0.0000
174	K	A	-2.5094
175	Q	A	-1.4128
176	C	A	-0.2554
177	S	A	0.0000
178	P	A	0.0521
179	I	A	1.5472
180	I	A	0.0000
181	R	A	-0.3584
182	A	A	0.4031
183	D	A	0.0000
184	L	A	0.0000
185	N	A	-0.7710
186	I	A	0.2158
187	V	A	0.0000
188	R	A	-1.1657
189	S	A	-0.5360
190	C	A	0.0000
191	T	A	0.0000
192	S	A	-0.8716
193	N	A	-1.2614
194	V	A	-0.8520
195	P	A	-0.9601
196	S	A	-1.5345
197	K	A	-2.0055
198	A	A	-1.4314
199	V	A	-0.7991
200	L	A	0.0000
201	S	A	-0.6230
202	C	A	0.0000
203	D	A	-1.5135
204	L	A	0.0000
205	T	A	0.0000
206	C	A	0.0000
207	F	A	0.0000
208	V	A	-0.3837
209	G	A	0.0000
210	S	A	-1.4719
211	E	A	-1.9389
212	D	A	-0.6808
213	I	A	0.9433
214	A	A	-0.2041
215	K	A	-1.9326
216	D	A	-1.9844
217	M	A	0.0000
218	E	A	-2.6485
219	A	A	-2.3609
220	W	A	0.0000
221	K	A	-3.1681
222	D	A	-3.1319
223	V	A	-1.5826
224	T	A	0.0000
225	S	A	-1.4310
226	G	A	-1.6977
227	N	A	-2.1625
228	A	A	-2.1949
229	K	A	-1.5420
230	I	A	-0.3460
231	Y	A	-0.1914
232	Q	A	-1.0963
233	L	A	0.0000
234	P	A	-1.0508
235	G	A	-0.9966
236	G	A	-0.4892
237	H	A	0.1436
238	F	A	0.4696
239	Y	A	0.0000
240	L	A	0.0000
241	L	A	-0.0694
242	D	A	-0.9012
243	P	A	-0.9842
244	A	A	-0.7953
245	N	A	0.0000
246	E	A	-1.3354
247	K	A	-1.8667
248	L	A	-0.4808
249	I	A	0.0000
250	K	A	0.0000
251	N	A	-1.6882
252	Y	A	-0.9324
253	I	A	0.0000
254	I	A	-1.0242
255	K	A	-1.5275
256	C	A	-0.5259
257	L	A	0.0000
258	E	A	-0.2398
259	V	A	1.4245
260	S	A	0.5625
261	S	A	0.6109
262	I	A	2.0849
263	S	A	0.8813
264	N	A	0.0140
265	F	A	1.5551