Project name: 65daec501601a6f

Chain sequence(s)	A: IVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:06)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:07)

• Minimal score value: -3.731
• Maximal score value: 1.148
• Average score: -0.5572
• Total score value: -124.2483

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
16	I	A	0.0000
17	V	A	0.0000
18	G	A	-1.1583
19	G	A	-0.5319
20	Y	A	0.5227
21	T	A	0.3163
22	C	A	0.1295
23	G	A	-0.0676
24	A	A	-0.6629
25	N	A	-0.9862
26	T	A	-0.5964
27	V	A	0.0000
28	P	A	-0.8742
29	Y	A	0.0000
30	Q	A	0.0000
31	V	A	0.0000
32	S	A	0.0000
33	L	A	0.0000
34	N	A	0.1355
37	S	A	-0.2163
38	G	A	0.0172
39	Y	A	0.9624
40	H	A	0.0000
41	F	A	0.3922
42	C	A	0.0000
43	G	A	0.0000
44	G	A	0.0000
45	S	A	0.0000
46	L	A	0.0000
47	I	A	-0.1094
48	N	A	-0.4705
49	S	A	-0.4130
50	Q	A	-1.1758
51	W	A	0.0000
52	V	A	0.0000
53	V	A	0.0000
54	S	A	0.0000
55	A	A	0.0000
56	A	A	0.0000
57	H	A	-0.1286
58	C	A	0.0000
59	Y	A	0.8539
60	K	A	-0.3795
61	S	A	-0.6726
62	G	A	-0.8865
63	I	A	0.0000
64	Q	A	-0.4409
65	V	A	0.0000
66	R	A	-0.0301
67	L	A	0.0000
69	G	A	0.0000
70	E	A	0.0000
71	D	A	-0.5822
72	N	A	-0.4145
73	I	A	-0.1377
74	N	A	-0.4121
75	V	A	1.1478
76	V	A	1.1480
77	E	A	-1.0511
78	G	A	-0.9978
79	N	A	-1.3935
80	E	A	-0.7547
81	Q	A	-0.0759
82	F	A	0.8198
83	I	A	-0.1007
84	S	A	-0.7082
85	A	A	-1.0774
86	S	A	-1.3896
87	K	A	-1.3058
88	S	A	-0.1366
89	I	A	0.4958
90	V	A	0.6631
91	H	A	-0.0353
92	P	A	-0.2878
93	S	A	-0.4847
94	Y	A	-0.6349
95	N	A	-1.3992
96	S	A	-1.2771
97	N	A	-1.5847
98	T	A	-1.1924
99	L	A	-0.8446
100	N	A	-0.9466
101	N	A	-0.6635
102	D	A	0.0000
103	I	A	0.0000
104	M	A	0.0000
105	L	A	0.0000
106	I	A	0.0000
107	K	A	-1.3640
108	L	A	0.0000
109	K	A	-2.1516
110	S	A	-1.2138
111	A	A	-0.6702
112	A	A	0.0000
113	S	A	-0.3312
114	L	A	-0.1801
115	N	A	-1.5163
116	S	A	-1.5669
117	R	A	-2.3602
118	V	A	0.0000
119	A	A	-0.6905
120	S	A	-0.3883
121	I	A	-0.1122
122	S	A	-0.3127
123	L	A	-0.1676
124	P	A	0.0000
125	T	A	-0.0076
127	S	A	-0.0067
128	C	A	0.3412
129	A	A	-0.0758
130	S	A	-0.4696
132	A	A	-0.6918
133	G	A	-0.7863
134	T	A	-0.8882
135	Q	A	-1.6755
136	C	A	0.0000
137	L	A	-0.6220
138	I	A	0.0000
139	S	A	0.0000
140	G	A	0.0000
141	W	A	0.0000
142	G	A	0.0000
143	N	A	0.0000
144	T	A	-1.0134
145	K	A	-1.9514
146	S	A	-1.6317
147	S	A	-1.1927
148	G	A	-1.0631
149	T	A	-0.8748
150	S	A	-0.5455
151	Y	A	-0.1276
152	P	A	-0.5151
153	D	A	-1.1984
154	V	A	-0.3729
155	L	A	0.0000
156	K	A	-0.1955
157	C	A	0.0000
158	L	A	0.0000
159	K	A	-1.8120
160	A	A	0.0000
161	P	A	-0.9287
162	I	A	0.0000
163	L	A	-0.4954
164	S	A	-1.2345
165	D	A	-2.2911
166	S	A	-1.6382
167	S	A	-1.3168
168	C	A	0.0000
169	K	A	-2.4361
170	S	A	-1.6951
171	A	A	-1.6573
172	Y	A	0.0000
173	P	A	-1.3425
174	G	A	-1.4360
175	Q	A	-1.6991
176	I	A	-1.2916
177	T	A	-0.8752
178	S	A	-0.6898
179	N	A	-0.6242
180	M	A	0.0000
181	F	A	-0.4997
182	C	A	0.0000
183	A	A	0.0000
184A	G	A	0.0000
184	Y	A	-1.0625
185	L	A	-1.8916
186	E	A	-2.9858
187	G	A	-2.8203
188A	G	A	-2.0361
188	K	A	-2.2018
189	D	A	0.0000
190	S	A	0.0000
191	C	A	-0.9682
192	Q	A	-1.2730
193	G	A	-0.4287
194	D	A	0.0000
195	S	A	-0.2851
196	G	A	0.0000
197	G	A	0.0000
198	P	A	0.0000
199	V	A	0.0000
200	V	A	-0.3912
201	C	A	0.0000
202	S	A	-0.7204
203	G	A	-0.7045
204	K	A	-0.6128
209	L	A	0.0000
210	Q	A	0.0000
211	G	A	0.0000
212	I	A	0.0000
213	V	A	0.0000
214	S	A	0.0000
215	W	A	-0.1550
216	G	A	-0.6650
217	S	A	-1.0558
219	G	A	-1.2525
220	C	A	-1.5513
221A	A	A	0.0000
221	Q	A	-3.0490
222	K	A	-3.7310
223	N	A	-2.9042
224	K	A	-2.2808
225	P	A	0.0000
226	G	A	0.0000
227	V	A	0.0000
228	Y	A	0.0000
229	T	A	0.0000
230	K	A	-0.5132
231	V	A	0.0000
232	C	A	-0.2589
233	N	A	-0.8792
234	Y	A	0.0000
235	V	A	-0.6140
236	S	A	-1.0151
237	W	A	-0.8410
238	I	A	0.0000
239	K	A	-2.0964
240	Q	A	-2.0764
241	T	A	-1.2277
242	I	A	-1.1452
243	A	A	-1.1223
244	S	A	-1.2381
245	N	A	-1.5558