%0 Journal Article %J Protein Science, 29:211-222 %D 2020 %T Flexible docking of peptides to proteins using CABS-dock %A Mateusz Kurcinski %A Aleksandra E. Badaczewska-Dawid %A Michal Kolinski %A Andrzej Koliński %A Sebastian Kmiecik %K molecular modeling %K peptide drugs %K peptide therapeutics %K protein–peptide complex %K protein–peptide interactions %K structure prediction %X Molecular docking of peptides to proteins can be a useful tool in the exploration of the possible peptide binding sites and poses. CABS-dock is a method for protein–peptide docking that features significant conformational flexibility of both the peptide and the protein molecules during the peptide search for a binding site. The CABS-dock has been made available as a web server and a standalone package. The web server is an easy to use tool with a simple web interface. The standalone package is a command-line program dedicated to professional users. It offers a number of advanced features, analysis tools and support for large-sized systems. In this article, we outline the current status of the CABS-dock method, its recent developments, applications, and challenges ahead. %B Protein Science, 29:211-222 %G eng %U https://onlinelibrary.wiley.com/doi/abs/10.1002/pro.3771 %R 10.1002/pro.3771