Andrzej Kolinski Research Group

Coarse-grained protein modeling

Modeling Software & Servers

Biomolecules — dynamics & interactions

0
-1
-2
-3

Mechanical unfolding of DDFLN4 studied by the coarse-grained knowledge-based CABS model

Source:

TASK Quarterly, 18: 373–378, 2014

Abstract

Mechanical unfolding of the fourth domain of Distyostelium discoideum filamin (DDFLN4) was studied using a CABS – coarse-grained knowledge-based protein model. Our study demonstrates that CABS is capable of reproducing the unfolding free energy landscape of protein unfolding and highlights an important role of non-native interactions in the protein unfolding process. The obtained three peaks in the force-extension profile suggest a four-state picture of DDFLN4 protein unfolding and correspond reasonably to the results of the all-atom simulation in explicit solvent.

The buy online buy viagra jelly https://www.levitradosageus24.com/ quickest solution to freeing up valuable storage on your phone by automatically identifying unwanted photosGallery Doctor is the only app that automatically identifies photos with bad lighting, blurry shots, similar photos, and even photos that we think you may find boring.