Andrzej Kolinski Research Group

Coarse-grained protein modeling

Modeling Software & Servers

Biomolecules — dynamics & interactions


Prediction of protein secondary structure by an enhanced neural network


Acta Biochimica Polonica, Polish Biochemical Society, 38, 1991


Computational model of neural network is used for prediction of secondary structure of globular proteins of known sequence. In contrast to earlier works some information about expected tertiary interactions were built in into the neural network. As a result the prediction accuracy was improved by 3% to 5%. Possible applications of this new approach are briefly discussed.