Project name: 3giz:H

Chain sequence(s)	H: EVQLVESGGGLVQPGRSLRLSCAASGFTFNDYAMHWVRQAPGKGLEWVSTISWNSGSIGYADSVKGRFTISRDNAKKSLYLQMNSLRAEDTALYYCAKDIQYGNYYYGMDVWGQGTTVTVSSASTKGPSVFPLAPGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEP
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -2.9212
• Maximal score value: 2.5106
• Average score: -0.5198
• Total score value: -112.2787

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.8096
2	V	H	-0.6091
3	Q	H	-0.7457
4	L	H	0.0000
5	V	H	1.2427
6	E	H	0.0000
7	S	H	-0.4259
8	G	H	-1.0150
9	G	H	-0.6353
10	G	H	-0.2613
11	L	H	0.0936
12	V	H	-0.6309
13	Q	H	-1.3756
14	P	H	-1.9184
15	G	H	-2.0668
16	R	H	-2.5918
17	S	H	-2.0260
18	L	H	-1.4355
19	R	H	-2.1393
20	L	H	0.0000
21	S	H	-0.3574
22	C	H	0.0000
23	A	H	-0.0660
24	A	H	0.0000
25	S	H	-0.7961
26	G	H	-0.9833
27	F	H	-0.5019
28	T	H	-0.5717
29	F	H	0.0000
30	N	H	-2.0521
31	D	H	-0.7977
32	Y	H	-0.1539
33	A	H	0.0000
34	M	H	0.0000
35	H	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.6812
40	A	H	-1.2337
41	P	H	-1.2273
42	G	H	-1.5968
43	K	H	-2.1563
44	G	H	-1.0882
45	L	H	0.3517
46	E	H	-0.6986
47	W	H	0.0672
48	V	H	0.0000
49	S	H	0.0000
50	T	H	0.4532
51	I	H	0.0000
52	S	H	-0.4425
53	W	H	-0.9538
54	N	H	-1.6642
55	S	H	-0.8325
56	G	H	-0.7007
57	S	H	-0.0572
58	I	H	0.9620
59	G	H	0.2630
60	Y	H	-0.4517
61	A	H	-1.3065
62	D	H	-2.3511
63	S	H	-1.7997
64	V	H	0.0000
65	K	H	-2.5483
66	G	H	-1.7341
67	R	H	-1.3583
68	F	H	0.0000
69	T	H	-0.7089
70	I	H	0.0000
71	S	H	-0.1971
72	R	H	-1.1567
73	D	H	-1.6656
74	N	H	-2.0648
75	A	H	-1.5317
76	K	H	-2.4035
77	K	H	-2.0622
78	S	H	-1.0865
79	L	H	0.0000
80	Y	H	-0.5293
81	L	H	0.0000
82	Q	H	-1.2624
83	M	H	0.0000
84	N	H	-1.9827
85	S	H	-1.8135
86	L	H	0.0000
87	R	H	-2.6370
88	A	H	-1.7168
89	E	H	-2.3142
90	D	H	0.0000
91	T	H	-0.9005
92	A	H	0.0000
93	L	H	0.0670
94	Y	H	0.0000
95	Y	H	0.3771
96	C	H	0.0000
97	A	H	0.0000
98	K	H	0.0000
99	D	H	0.0000
100	I	H	0.9756
101	Q	H	1.3775
102	Y	H	1.4717
103	G	H	0.1584
104	N	H	0.5168
105	Y	H	1.9883
106	Y	H	2.5073
107	Y	H	2.2202
108	G	H	0.7676
109	M	H	-0.0323
110	D	H	-1.1797
111	V	H	-0.3177
112	W	H	0.0616
113	G	H	-0.0137
114	Q	H	-0.8393
115	G	H	-0.2610
116	T	H	-0.1981
117	T	H	-0.3845
118	V	H	0.0000
119	T	H	-0.4541
120	V	H	0.0000
121	S	H	-0.7195
122	S	H	-0.3590
123	A	H	-0.3508
124	S	H	-0.5206
125	T	H	-0.8732
126	K	H	-1.4401
127	G	H	-1.6598
128	P	H	-0.7617
129	S	H	-0.1233
130	V	H	0.0000
131	F	H	1.0570
132	P	H	0.1107
133	L	H	0.4989
134	A	H	-0.5295
135	P	H	0.0000
136	G	H	-0.6591
143	G	H	-0.6557
144	T	H	-0.4655
145	A	H	-0.3343
146	A	H	0.0227
147	L	H	0.0000
148	G	H	0.0000
149	C	H	0.0000
150	L	H	0.7262
151	V	H	0.0000
152	K	H	-0.2724
153	D	H	-0.7713
154	Y	H	0.0000
155	F	H	0.0000
156	P	H	0.0000
157	E	H	-1.0487
158	P	H	-1.2181
159	V	H	0.0000
160	T	H	-0.8586
161	V	H	-0.4768
162	S	H	-0.4767
163	W	H	0.0000
164	N	H	-0.8470
165	S	H	-0.6970
166	G	H	-0.5555
167	A	H	-0.2704
168	L	H	-0.0759
169	T	H	-0.3636
170	S	H	-0.4179
171	G	H	-0.5463
172	V	H	-0.1973
173	H	H	-0.6373
174	T	H	0.0467
175	F	H	0.8308
176	P	H	0.5921
177	A	H	1.1567
178	V	H	2.5106
179	L	H	2.0974
180	Q	H	0.7154
181	S	H	0.1044
182	S	H	-0.2310
183	G	H	0.1701
184	L	H	0.1689
185	Y	H	0.6074
186	S	H	0.0000
187	L	H	0.0000
188	S	H	0.6055
189	S	H	0.0000
190	V	H	0.2863
191	V	H	0.0000
192	T	H	-0.2759
193	V	H	0.0000
194	P	H	-0.6129
195	S	H	-0.5916
196	S	H	-0.6280
197	S	H	-0.6216
198	L	H	-0.8276
199	G	H	-0.9943
200	T	H	-0.7574
201	Q	H	-1.3230
202	T	H	-1.1489
203	Y	H	0.0000
204	I	H	-1.3825
205	C	H	0.0000
206	N	H	-1.6605
207	V	H	0.0000
208	N	H	-2.3835
209	H	H	0.0000
210	K	H	-2.9212
211	P	H	-1.7659
212	S	H	-1.9587
213	N	H	-2.6680
214	T	H	-2.2614
215	K	H	-2.8243
216	V	H	-1.7784
217	D	H	-2.7483
218	K	H	-2.1114
219	K	H	-2.5751
220	V	H	0.0000
221	E	H	-2.5023
222	P	H	-1.2096