Project name: 3C Model
Status: done
submitted: 2018-11-17 07:18:35, status changed: 2018-11-17 07:24:24
Settings
|
Chain sequence(s)
|
A: MALGLLCLCFTLMGTLHSQAKYIPPMMIPAPPLSKIPLHPDFQDDQFQGKWFGIGIAGNSIWKRKGSSYEYSMYSDTYHLKDDHSYNFTTTIFRNDECVQWNQRFVPCGEPGQFSLDNETLSNGLDIYTVRVTVTDYTQFAMMYAVVKFENVIYFQTKLNGRTKKLNSEVKQRFIEFSKSLGLGDDNIVFFQPIGN
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-3.4857
-
Maximal score value
-
2.615
-
Average score
-
-0.614
-
Total score value
-
-120.3407
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
M |
A |
2.2962 |
|
| 2 |
A |
A |
1.9608 |
|
| 3 |
L |
A |
2.4955 |
|
| 4 |
G |
A |
1.5782 |
|
| 5 |
L |
A |
2.2184 |
|
| 6 |
L |
A |
2.6150 |
|
| 7 |
C |
A |
2.1671 |
|
| 8 |
L |
A |
1.7595 |
|
| 9 |
C |
A |
1.6666 |
|
| 10 |
F |
A |
1.3445 |
|
| 11 |
T |
A |
1.2678 |
|
| 12 |
L |
A |
0.0000 |
|
| 13 |
M |
A |
0.8022 |
|
| 14 |
G |
A |
0.0000 |
|
| 15 |
T |
A |
0.2754 |
|
| 16 |
L |
A |
0.0000 |
|
| 17 |
H |
A |
0.4822 |
|
| 18 |
S |
A |
0.3153 |
|
| 19 |
Q |
A |
-0.1632 |
|
| 20 |
A |
A |
0.0000 |
|
| 21 |
K |
A |
0.4482 |
|
| 22 |
Y |
A |
1.5290 |
|
| 23 |
I |
A |
1.6963 |
|
| 24 |
P |
A |
1.2195 |
|
| 25 |
P |
A |
1.0946 |
|
| 26 |
M |
A |
1.5971 |
|
| 27 |
M |
A |
1.3175 |
|
| 28 |
I |
A |
0.9801 |
|
| 29 |
P |
A |
0.0943 |
|
| 30 |
A |
A |
0.0593 |
|
| 31 |
P |
A |
0.0000 |
|
| 32 |
P |
A |
-0.6428 |
|
| 33 |
L |
A |
-0.6058 |
|
| 34 |
S |
A |
-0.9097 |
|
| 35 |
K |
A |
-1.5296 |
|
| 36 |
I |
A |
0.0000 |
|
| 37 |
P |
A |
-0.4095 |
|
| 38 |
L |
A |
-0.5642 |
|
| 39 |
H |
A |
-0.6255 |
|
| 40 |
P |
A |
-1.0858 |
|
| 41 |
D |
A |
-2.0377 |
|
| 42 |
F |
A |
-1.7722 |
|
| 43 |
Q |
A |
-2.2860 |
|
| 44 |
D |
A |
-2.4325 |
|
| 45 |
D |
A |
-2.6494 |
|
| 46 |
Q |
A |
-1.6796 |
|
| 47 |
F |
A |
0.0000 |
|
| 48 |
Q |
A |
-2.1415 |
|
| 49 |
G |
A |
-1.8853 |
|
| 50 |
K |
A |
-2.2406 |
|
| 51 |
W |
A |
0.0000 |
|
| 52 |
F |
A |
-0.8363 |
|
| 53 |
G |
A |
0.0000 |
|
| 54 |
I |
A |
0.0000 |
|
| 55 |
G |
A |
0.0000 |
|
| 56 |
I |
A |
0.0000 |
|
| 57 |
A |
A |
0.0000 |
|
| 58 |
G |
A |
0.0000 |
|
| 59 |
N |
A |
0.0000 |
|
| 60 |
S |
A |
0.0000 |
|
| 61 |
I |
A |
0.0000 |
|
| 62 |
W |
A |
-0.8500 |
|
| 63 |
K |
A |
0.0000 |
|
| 64 |
R |
A |
-2.1969 |
|
| 65 |
K |
A |
-3.1514 |
|
| 66 |
G |
A |
-2.1087 |
|
| 67 |
S |
A |
-1.7908 |
|
| 68 |
S |
A |
-1.2607 |
|
| 69 |
Y |
A |
0.0000 |
|
| 70 |
E |
A |
-2.1685 |
|
| 71 |
Y |
A |
-0.6706 |
|
| 72 |
S |
A |
-0.5103 |
|
| 73 |
M |
A |
0.0000 |
|
| 74 |
Y |
A |
0.3265 |
|
| 75 |
S |
A |
0.0000 |
|
| 76 |
D |
A |
0.0000 |
|
| 77 |
T |
A |
-1.2811 |
|
| 78 |
Y |
A |
0.0000 |
|
| 79 |
H |
A |
-2.1387 |
|
| 80 |
L |
A |
-2.6254 |
|
| 81 |
K |
A |
-3.4857 |
|
| 82 |
D |
A |
-3.4175 |
|
| 83 |
D |
A |
-3.3420 |
|
| 84 |
H |
A |
-2.9045 |
|
| 85 |
S |
A |
-2.0516 |
|
| 86 |
Y |
A |
0.0000 |
|
| 87 |
N |
A |
-1.6232 |
|
| 88 |
F |
A |
-1.1331 |
|
| 89 |
T |
A |
-1.3032 |
|
| 90 |
T |
A |
0.0000 |
|
| 91 |
T |
A |
-0.2444 |
|
| 92 |
I |
A |
0.0000 |
|
| 93 |
F |
A |
-1.1363 |
|
| 94 |
R |
A |
-2.9548 |
|
| 95 |
N |
A |
-3.0452 |
|
| 96 |
D |
A |
-3.2896 |
|
| 97 |
E |
A |
-2.4661 |
|
| 98 |
C |
A |
-0.8379 |
|
| 99 |
V |
A |
-0.5830 |
|
| 100 |
Q |
A |
-1.0653 |
|
| 101 |
W |
A |
-0.8900 |
|
| 102 |
N |
A |
-1.6815 |
|
| 103 |
Q |
A |
-1.3464 |
|
| 104 |
R |
A |
-1.5220 |
|
| 105 |
F |
A |
0.0000 |
|
| 106 |
V |
A |
-0.5070 |
|
| 107 |
P |
A |
-0.9956 |
|
| 108 |
C |
A |
-0.6576 |
|
| 109 |
G |
A |
-1.3175 |
|
| 110 |
E |
A |
-2.1039 |
|
| 111 |
P |
A |
-1.7541 |
|
| 112 |
G |
A |
0.0000 |
|
| 113 |
Q |
A |
-0.8825 |
|
| 114 |
F |
A |
0.0000 |
|
| 115 |
S |
A |
0.0000 |
|
| 116 |
L |
A |
0.0000 |
|
| 117 |
D |
A |
-0.6825 |
|
| 118 |
N |
A |
-0.2385 |
|
| 119 |
E |
A |
-0.3573 |
|
| 120 |
T |
A |
0.0992 |
|
| 121 |
L |
A |
0.8592 |
|
| 122 |
S |
A |
-0.4281 |
|
| 123 |
N |
A |
-1.4777 |
|
| 124 |
G |
A |
-1.5816 |
|
| 125 |
L |
A |
0.0000 |
|
| 126 |
D |
A |
-1.8053 |
|
| 127 |
I |
A |
-0.1623 |
|
| 128 |
Y |
A |
0.1347 |
|
| 129 |
T |
A |
0.1805 |
|
| 130 |
V |
A |
0.0000 |
|
| 131 |
R |
A |
-0.6074 |
|
| 132 |
V |
A |
0.0000 |
|
| 133 |
T |
A |
0.0000 |
|
| 134 |
V |
A |
0.3262 |
|
| 135 |
T |
A |
0.0000 |
|
| 136 |
D |
A |
-0.2479 |
|
| 137 |
Y |
A |
-0.3595 |
|
| 138 |
T |
A |
-0.2707 |
|
| 139 |
Q |
A |
-0.9568 |
|
| 140 |
F |
A |
-0.2493 |
|
| 141 |
A |
A |
0.0000 |
|
| 142 |
M |
A |
0.0000 |
|
| 143 |
M |
A |
0.0000 |
|
| 144 |
Y |
A |
0.0000 |
|
| 145 |
A |
A |
0.0000 |
|
| 146 |
V |
A |
0.0000 |
|
| 147 |
V |
A |
0.0000 |
|
| 148 |
K |
A |
-0.8585 |
|
| 149 |
F |
A |
0.0000 |
|
| 150 |
E |
A |
-2.7082 |
|
| 151 |
N |
A |
-2.0840 |
|
| 152 |
V |
A |
-0.5647 |
|
| 153 |
I |
A |
0.1227 |
|
| 154 |
Y |
A |
0.4485 |
|
| 155 |
F |
A |
0.0000 |
|
| 156 |
Q |
A |
-0.1530 |
|
| 157 |
T |
A |
0.0000 |
|
| 158 |
K |
A |
-0.0628 |
|
| 159 |
L |
A |
0.0000 |
|
| 160 |
N |
A |
0.0000 |
|
| 161 |
G |
A |
0.0000 |
|
| 162 |
R |
A |
-2.2412 |
|
| 163 |
T |
A |
-2.0113 |
|
| 164 |
K |
A |
-2.2306 |
|
| 165 |
K |
A |
-2.7726 |
|
| 166 |
L |
A |
0.0000 |
|
| 167 |
N |
A |
-2.5400 |
|
| 168 |
S |
A |
-2.2609 |
|
| 169 |
E |
A |
-2.6275 |
|
| 170 |
V |
A |
0.0000 |
|
| 171 |
K |
A |
-1.8774 |
|
| 172 |
Q |
A |
-2.7652 |
|
| 173 |
R |
A |
-2.7159 |
|
| 174 |
F |
A |
0.0000 |
|
| 175 |
I |
A |
-1.5711 |
|
| 176 |
E |
A |
-2.2099 |
|
| 177 |
F |
A |
-1.1200 |
|
| 178 |
S |
A |
0.0000 |
|
| 179 |
K |
A |
-1.8486 |
|
| 180 |
S |
A |
-1.0439 |
|
| 181 |
L |
A |
0.0000 |
|
| 182 |
G |
A |
-0.9126 |
|
| 183 |
L |
A |
0.0000 |
|
| 184 |
G |
A |
-1.9082 |
|
| 185 |
D |
A |
-3.1066 |
|
| 186 |
D |
A |
-3.1098 |
|
| 187 |
N |
A |
0.0000 |
|
| 188 |
I |
A |
0.0000 |
|
| 189 |
V |
A |
0.0000 |
|
| 190 |
F |
A |
0.7526 |
|
| 191 |
F |
A |
0.1662 |
|
| 192 |
Q |
A |
-0.7548 |
|
| 193 |
P |
A |
-0.7020 |
|
| 194 |
I |
A |
-0.4029 |
|
| 195 |
G |
A |
-0.9921 |
|
| 196 |
N |
A |
-1.6646 |
|