Project name: 6bah:B
Status: done
submitted: 2019-03-21 13:12:01, status changed: 2019-03-21 13:23:31
Settings
|
Chain sequence(s)
|
B: EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQSPGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAIYYCCSRWGGDGFYAMDYWGQGTLVTVSSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKKDYFPEPVTVSWNSGALTSGVHTFPCVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC
|
| Distance of aggregation |
10 Å |
| Dynamic mode |
No
|
Drag cursor over the plot to display residue labels.
-
Minimal score value
-
-2.9101
-
Maximal score value
-
2.6143
-
Average score
-
-0.5375
-
Total score value
-
-119.8544
The table below lists A3D score for protein residues.
Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index |
residue name |
chain |
Aggrescan3D score |
mutation |
| residue index |
residue name |
chain |
Aggrescan3D score |
|
| 1 |
E |
B |
-2.0189 |
|
| 2 |
V |
B |
-1.1561 |
|
| 3 |
Q |
B |
-0.8404 |
|
| 4 |
L |
B |
0.0000 |
|
| 5 |
V |
B |
0.4815 |
|
| 6 |
E |
B |
0.0000 |
|
| 7 |
S |
B |
-0.5342 |
|
| 8 |
G |
B |
-0.9026 |
|
| 9 |
G |
B |
-0.4334 |
|
| 10 |
G |
B |
-0.4357 |
|
| 11 |
L |
B |
-0.0825 |
|
| 12 |
V |
B |
0.0000 |
|
| 13 |
Q |
B |
-1.6210 |
|
| 14 |
P |
B |
-1.6491 |
|
| 15 |
G |
B |
-1.4077 |
|
| 16 |
G |
B |
-1.1225 |
|
| 17 |
S |
B |
-1.1656 |
|
| 18 |
L |
B |
-1.1427 |
|
| 19 |
R |
B |
-2.0181 |
|
| 20 |
L |
B |
0.0000 |
|
| 21 |
S |
B |
-0.4594 |
|
| 22 |
C |
B |
0.0000 |
|
| 23 |
A |
B |
-0.2089 |
|
| 24 |
A |
B |
0.0000 |
|
| 25 |
S |
B |
-1.1028 |
|
| 26 |
G |
B |
-1.3389 |
|
| 27 |
F |
B |
-1.5397 |
|
| 28 |
N |
B |
-2.1925 |
|
| 29 |
I |
B |
0.0000 |
|
| 30 |
K |
B |
-2.6793 |
|
| 31 |
D |
B |
-2.8597 |
|
| 32 |
T |
B |
0.0000 |
|
| 33 |
Y |
B |
0.0546 |
|
| 34 |
I |
B |
0.0000 |
|
| 35 |
H |
B |
0.0000 |
|
| 36 |
W |
B |
0.0000 |
|
| 37 |
V |
B |
0.0000 |
|
| 38 |
R |
B |
0.0000 |
|
| 39 |
Q |
B |
-0.1281 |
|
| 40 |
S |
B |
-0.6876 |
|
| 41 |
P |
B |
-0.8246 |
|
| 42 |
G |
B |
-1.2435 |
|
| 43 |
K |
B |
-1.1006 |
|
| 44 |
G |
B |
-0.2452 |
|
| 45 |
L |
B |
0.9146 |
|
| 46 |
E |
B |
0.1172 |
|
| 47 |
W |
B |
0.2858 |
|
| 48 |
V |
B |
0.0000 |
|
| 49 |
A |
B |
0.0000 |
|
| 50 |
R |
B |
-1.1284 |
|
| 51 |
I |
B |
0.0000 |
|
| 52 |
Y |
B |
-0.4869 |
|
| 53 |
P |
B |
-1.0953 |
|
| 54 |
T |
B |
-1.1630 |
|
| 55 |
N |
B |
-0.9130 |
|
| 56 |
G |
B |
-0.4273 |
|
| 57 |
Y |
B |
0.3848 |
|
| 58 |
T |
B |
-0.6873 |
|
| 59 |
R |
B |
-2.2203 |
|
| 60 |
Y |
B |
-2.0145 |
|
| 61 |
A |
B |
-1.8470 |
|
| 62 |
D |
B |
-2.6963 |
|
| 63 |
S |
B |
-1.6463 |
|
| 64 |
V |
B |
0.0000 |
|
| 65 |
K |
B |
-2.9101 |
|
| 66 |
G |
B |
-1.8160 |
|
| 67 |
R |
B |
-1.4376 |
|
| 68 |
F |
B |
0.0000 |
|
| 69 |
T |
B |
-1.1769 |
|
| 70 |
I |
B |
0.0000 |
|
| 71 |
S |
B |
-0.1795 |
|
| 72 |
A |
B |
-0.7079 |
|
| 73 |
D |
B |
-1.2386 |
|
| 74 |
T |
B |
-1.5013 |
|
| 75 |
S |
B |
-1.5058 |
|
| 76 |
K |
B |
-2.1675 |
|
| 77 |
N |
B |
-1.7318 |
|
| 78 |
T |
B |
-0.8691 |
|
| 79 |
A |
B |
0.0000 |
|
| 80 |
Y |
B |
-0.4408 |
|
| 81 |
L |
B |
0.0000 |
|
| 82 |
Q |
B |
-1.1068 |
|
| 83 |
M |
B |
0.0000 |
|
| 84 |
N |
B |
-1.4389 |
|
| 85 |
S |
B |
-1.2612 |
|
| 86 |
L |
B |
0.0000 |
|
| 87 |
R |
B |
-2.2078 |
|
| 88 |
A |
B |
-1.6864 |
|
| 89 |
E |
B |
-2.3949 |
|
| 90 |
D |
B |
0.0000 |
|
| 91 |
T |
B |
-0.7767 |
|
| 92 |
A |
B |
0.0000 |
|
| 93 |
I |
B |
0.5523 |
|
| 94 |
Y |
B |
0.0000 |
|
| 95 |
Y |
B |
0.3755 |
|
| 96 |
C |
B |
0.0000 |
|
| 97 |
S |
B |
0.0000 |
|
| 98 |
R |
B |
0.0000 |
|
| 99 |
W |
B |
0.6646 |
|
| 100 |
G |
B |
0.3901 |
|
| 101 |
G |
B |
0.0000 |
|
| 102 |
D |
B |
-1.5227 |
|
| 103 |
G |
B |
-0.2219 |
|
| 104 |
F |
B |
1.7663 |
|
| 105 |
Y |
B |
1.9471 |
|
| 106 |
A |
B |
1.2910 |
|
| 107 |
M |
B |
0.9785 |
|
| 108 |
D |
B |
0.3781 |
|
| 109 |
Y |
B |
0.4248 |
|
| 110 |
W |
B |
0.4403 |
|
| 111 |
G |
B |
-0.0892 |
|
| 112 |
Q |
B |
-0.7975 |
|
| 113 |
G |
B |
-0.1907 |
|
| 114 |
T |
B |
0.0619 |
|
| 115 |
L |
B |
0.3669 |
|
| 116 |
V |
B |
0.0000 |
|
| 117 |
T |
B |
-0.3510 |
|
| 118 |
V |
B |
0.0000 |
|
| 119 |
S |
B |
-0.7616 |
|
| 120 |
S |
B |
-0.7096 |
|
| 121 |
A |
B |
-0.4470 |
|
| 122 |
S |
B |
-0.5479 |
|
| 123 |
T |
B |
-0.5570 |
|
| 124 |
K |
B |
-1.1033 |
|
| 125 |
G |
B |
-1.4027 |
|
| 126 |
P |
B |
0.0000 |
|
| 127 |
S |
B |
-0.0516 |
|
| 128 |
V |
B |
0.0000 |
|
| 129 |
F |
B |
0.9783 |
|
| 130 |
P |
B |
0.0928 |
|
| 131 |
L |
B |
0.3287 |
|
| 132 |
A |
B |
-1.0166 |
|
| 133 |
P |
B |
0.0000 |
|
| 134 |
S |
B |
-1.2565 |
|
| 135 |
S |
B |
-1.1259 |
|
| 136 |
K |
B |
-1.8788 |
|
| 137 |
S |
B |
-0.9738 |
|
| 138 |
T |
B |
-0.9812 |
|
| 139 |
S |
B |
-0.9491 |
|
| 140 |
G |
B |
-0.8577 |
|
| 141 |
G |
B |
-0.9190 |
|
| 142 |
T |
B |
-0.6356 |
|
| 143 |
A |
B |
0.0000 |
|
| 144 |
A |
B |
-0.1950 |
|
| 145 |
L |
B |
0.0000 |
|
| 146 |
G |
B |
0.0000 |
|
| 147 |
C |
B |
0.0000 |
|
| 148 |
L |
B |
0.7124 |
|
| 149 |
V |
B |
0.0000 |
|
| 150 |
K |
B |
-0.1676 |
|
| 151 |
D |
B |
-0.3728 |
|
| 152 |
Y |
B |
0.0000 |
|
| 153 |
F |
B |
0.0000 |
|
| 154 |
P |
B |
0.0000 |
|
| 155 |
E |
B |
-0.4247 |
|
| 156 |
P |
B |
-0.5413 |
|
| 157 |
V |
B |
-0.5679 |
|
| 158 |
T |
B |
-0.4917 |
|
| 159 |
V |
B |
-0.1151 |
|
| 160 |
S |
B |
-0.3266 |
|
| 161 |
W |
B |
0.0000 |
|
| 162 |
N |
B |
-0.7399 |
|
| 163 |
S |
B |
-0.6250 |
|
| 164 |
G |
B |
-0.5075 |
|
| 165 |
A |
B |
-0.2367 |
|
| 166 |
L |
B |
-0.0181 |
|
| 167 |
T |
B |
-0.2978 |
|
| 168 |
S |
B |
-0.3398 |
|
| 169 |
G |
B |
-0.4093 |
|
| 170 |
V |
B |
-0.0773 |
|
| 171 |
H |
B |
-0.5804 |
|
| 172 |
T |
B |
0.1004 |
|
| 173 |
F |
B |
0.9356 |
|
| 174 |
P |
B |
0.8032 |
|
| 175 |
C |
B |
1.5569 |
|
| 176 |
V |
B |
2.6143 |
|
| 177 |
L |
B |
2.2709 |
|
| 178 |
Q |
B |
0.7588 |
|
| 179 |
S |
B |
0.1032 |
|
| 180 |
S |
B |
-0.2155 |
|
| 181 |
G |
B |
0.1945 |
|
| 182 |
L |
B |
0.3473 |
|
| 183 |
Y |
B |
0.9906 |
|
| 184 |
S |
B |
0.0000 |
|
| 185 |
L |
B |
0.0000 |
|
| 186 |
S |
B |
0.6684 |
|
| 187 |
S |
B |
0.0000 |
|
| 188 |
V |
B |
0.3216 |
|
| 189 |
V |
B |
0.0000 |
|
| 190 |
T |
B |
-0.2301 |
|
| 191 |
V |
B |
0.0000 |
|
| 192 |
P |
B |
-0.6224 |
|
| 193 |
S |
B |
-0.5420 |
|
| 194 |
S |
B |
-0.5302 |
|
| 195 |
S |
B |
-0.5185 |
|
| 196 |
L |
B |
-0.6836 |
|
| 197 |
G |
B |
-1.0462 |
|
| 198 |
T |
B |
-0.6896 |
|
| 199 |
Q |
B |
-1.2266 |
|
| 200 |
T |
B |
-1.1320 |
|
| 201 |
Y |
B |
0.0000 |
|
| 202 |
I |
B |
-1.3274 |
|
| 203 |
C |
B |
0.0000 |
|
| 204 |
N |
B |
-1.3373 |
|
| 205 |
V |
B |
0.0000 |
|
| 206 |
N |
B |
-1.8114 |
|
| 207 |
H |
B |
0.0000 |
|
| 208 |
K |
B |
-2.7654 |
|
| 209 |
P |
B |
-1.5960 |
|
| 210 |
S |
B |
-1.8262 |
|
| 211 |
N |
B |
-2.5708 |
|
| 212 |
T |
B |
-2.0675 |
|
| 213 |
K |
B |
-2.6428 |
|
| 214 |
V |
B |
-1.5774 |
|
| 215 |
D |
B |
-2.2282 |
|
| 216 |
K |
B |
-1.9464 |
|
| 217 |
K |
B |
-2.4140 |
|
| 218 |
V |
B |
0.0000 |
|
| 219 |
E |
B |
-2.8521 |
|
| 220 |
P |
B |
-1.8310 |
|
| 221 |
K |
B |
-2.1108 |
|
| 222 |
S |
B |
-0.9559 |
|
| 223 |
C |
B |
0.1940 |
|