| Chain sequence(s) |
A: QGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGL C: RAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLP B: RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG E: QGWLKEIRKLQKSTHLLIRKLPFSRLAREICVKFTRGVDFNWQAQALLALQEAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGL D: RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA G: RAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLP F: RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG H: RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA N: MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQRQRKESVVQHLIHLCEEKRSDAALLDIIYMQFHQHQKMKQFKNSFKKVTVSFRETAVWIRIAWGTKPNQYKPTYVVYYSQRRNTPLLGQALTIASKH |
| Distance of aggregation | 5 Å |
| Dynamic mode | No |
| Mutated residues | AB34T |
| Energy difference between WT (input) and mutated protein (by FoldX) | -0.520732 kcal/mol
Changes in protein stability upon mutation are calculated using the FoldX forcefield. Computational prediction of protein stability is used with the intention of preventing the experimental characterization of proteins bearing mutations that significantly destabilize their structure. Mutations resulting in a predicted reduction in protein stability ≥ 1 kcal/mol are considered disruptive. |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 45 | Q | A | -1.2848 | |
| 46 | G | A | -0.8167 | |
| 47 | W | A | -0.0170 | |
| 48 | L | A | 0.0565 | |
| 49 | K | A | -1.5327 | |
| 50 | E | A | -1.2412 | |
| 51 | I | A | 0.0000 | |
| 52 | R | A | -2.1584 | |
| 53 | K | A | -2.0410 | |
| 54 | L | A | 0.0000 | |
| 55 | Q | A | 0.0000 | |
| 56 | K | A | -1.7151 | |
| 57 | S | A | -0.3982 | |
| 58 | T | A | -0.2197 | |
| 59 | H | A | -0.9352 | |
| 60 | L | A | 0.1203 | |
| 61 | L | A | 0.0000 | |
| 62 | I | A | 0.0000 | |
| 63 | R | A | -0.6641 | |
| 64 | K | A | -0.6983 | |
| 65 | L | A | 0.6133 | |
| 66 | P | A | 0.0000 | |
| 67 | F | A | 0.0000 | |
| 68 | S | A | -0.2020 | |
| 69 | R | A | -0.9758 | |
| 70 | L | A | 0.0000 | |
| 71 | A | A | 0.0000 | |
| 72 | R | A | -0.5379 | |
| 73 | E | A | -0.9338 | |
| 74 | I | A | 0.0000 | |
| 75 | C | A | 0.0000 | |
| 76 | V | A | 0.8411 | |
| 77 | K | A | -1.4248 | |
| 78 | F | A | 0.0207 | |
| 79 | T | A | -0.1078 | |
| 80 | R | A | -0.8721 | |
| 81 | G | A | -0.0333 | |
| 82 | V | A | 0.0012 | |
| 83 | D | A | -0.9782 | |
| 84 | F | A | 0.0000 | |
| 85 | N | A | -0.2558 | |
| 86 | W | A | 0.0000 | |
| 87 | Q | A | -0.3098 | |
| 88 | A | A | -0.1339 | |
| 89 | Q | A | -0.7008 | |
| 90 | A | A | 0.0000 | |
| 91 | L | A | 0.0000 | |
| 92 | L | A | 0.2802 | |
| 93 | A | A | 0.0000 | |
| 94 | L | A | 0.0000 | |
| 95 | Q | A | 0.0000 | |
| 96 | E | A | 0.0000 | |
| 97 | A | A | 0.0000 | |
| 98 | A | A | 0.0000 | |
| 99 | E | A | 0.0000 | |
| 100 | A | A | 0.0871 | |
| 101 | F | A | 0.4007 | |
| 102 | L | A | 0.0000 | |
| 103 | V | A | 0.0000 | |
| 104 | H | A | -0.7473 | |
| 105 | L | A | 0.0000 | |
| 106 | F | A | 0.0000 | |
| 107 | E | A | -1.1586 | |
| 108 | D | A | -0.4407 | |
| 109 | A | A | 0.0000 | |
| 110 | Y | A | 0.0000 | |
| 111 | L | A | 0.1781 | |
| 112 | L | A | 0.0000 | |
| 113 | T | A | 0.0000 | |
| 114 | L | A | 0.3154 | |
| 115 | H | A | -0.0482 | |
| 116 | A | A | -0.1008 | |
| 117 | G | A | -0.5478 | |
| 118 | R | A | -0.4616 | |
| 119 | V | A | 0.2996 | |
| 120 | T | A | 0.0000 | |
| 121 | L | A | 0.0000 | |
| 122 | F | A | 0.3527 | |
| 123 | P | A | -0.2826 | |
| 124 | K | A | -1.7062 | |
| 125 | D | A | 0.0000 | |
| 126 | V | A | 0.0000 | |
| 127 | Q | A | -1.0418 | |
| 128 | L | A | 0.0000 | |
| 129 | A | A | 0.0000 | |
| 130 | R | A | -1.0643 | |
| 131 | R | A | -1.9592 | |
| 132 | I | A | 0.0000 | |
| 133 | R | A | -0.7678 | |
| 134 | G | A | -0.3067 | |
| 135 | L | A | 1.4617 | |
| 24 | R | B | -2.1682 | |
| 25 | D | B | -2.1518 | |
| 26 | N | B | -0.5629 | |
| 27 | I | B | -0.0124 | |
| 28 | Q | B | -1.1662 | |
| 29 | G | B | -0.3373 | |
| 30 | I | B | 0.0000 | |
| 31 | T | B | -0.2612 | |
| 32 | K | B | -1.3614 | |
| 33 | P | B | -0.3442 | |
| 34 | T | B | 0.0000 | mutated: AB34T |
| 35 | I | B | 0.0000 | |
| 36 | R | B | -0.5640 | |
| 37 | R | B | -0.5256 | |
| 38 | L | B | 0.0000 | |
| 39 | A | B | 0.0000 | |
| 40 | R | B | 0.0000 | |
| 41 | R | B | 0.0000 | |
| 42 | G | B | -0.0515 | |
| 43 | G | B | 0.0000 | |
| 44 | V | B | 0.0000 | |
| 45 | K | B | -0.3127 | |
| 46 | R | B | -0.2418 | |
| 47 | I | B | 0.0000 | |
| 48 | S | B | 0.0000 | |
| 49 | G | B | 0.0624 | |
| 50 | L | B | 1.5056 | |
| 51 | I | B | 0.0000 | |
| 52 | Y | B | 0.0000 | |
| 53 | E | B | -1.8698 | |
| 54 | E | B | -0.6305 | |
| 55 | T | B | 0.0000 | |
| 56 | R | B | -0.2722 | |
| 57 | G | B | -0.2953 | |
| 58 | V | B | 0.0000 | |
| 59 | L | B | 0.0000 | |
| 60 | K | B | -0.6086 | |
| 61 | V | B | 1.4630 | |
| 62 | F | B | 0.0000 | |
| 63 | L | B | 0.0000 | |
| 64 | E | B | -1.5754 | |
| 65 | N | B | -1.2336 | |
| 66 | V | B | 0.0000 | |
| 67 | I | B | 0.0000 | |
| 68 | R | B | -0.3463 | |
| 69 | D | B | 0.0000 | |
| 70 | A | B | 0.0000 | |
| 71 | V | B | 0.0000 | |
| 72 | T | B | 0.0000 | |
| 73 | Y | B | 0.0000 | |
| 74 | T | B | 0.0000 | |
| 75 | E | B | -0.3638 | |
| 76 | H | B | 0.0000 | |
| 77 | A | B | -0.3082 | |
| 78 | K | B | -1.7425 | |
| 79 | R | B | -0.6557 | |
| 80 | K | B | -0.5905 | |
| 81 | T | B | 0.0000 | |
| 82 | V | B | 0.0000 | |
| 83 | T | B | -0.0105 | |
| 84 | A | B | 0.0437 | |
| 85 | M | B | 0.2151 | |
| 86 | D | B | 0.0000 | |
| 87 | V | B | 0.0000 | |
| 88 | V | B | 0.0000 | |
| 89 | Y | B | 0.1372 | |
| 90 | A | B | 0.0000 | |
| 91 | L | B | 0.0000 | |
| 92 | K | B | -0.8087 | |
| 93 | R | B | -0.9203 | |
| 94 | Q | B | -0.3742 | |
| 95 | G | B | -0.2234 | |
| 96 | R | B | -0.3649 | |
| 97 | T | B | 0.0000 | |
| 98 | L | B | 0.0000 | |
| 99 | Y | B | 0.0000 | |
| 100 | G | B | -0.0118 | |
| 101 | F | B | 0.2751 | |
| 102 | G | B | -0.1211 | |
| 103 | G | B | -0.4830 | |
| 12 | R | C | -1.8332 | |
| 13 | A | C | -0.5995 | |
| 14 | K | C | -1.6840 | |
| 15 | A | C | -0.5676 | |
| 16 | K | C | -1.5219 | |
| 17 | T | C | -0.3593 | |
| 18 | R | C | -0.3099 | |
| 19 | S | C | 0.0000 | |
| 20 | S | C | -0.2068 | |
| 21 | R | C | -0.3844 | |
| 22 | A | C | 0.0000 | |
| 23 | G | C | -0.4424 | |
| 24 | L | C | 0.0385 | |
| 25 | Q | C | -0.2863 | |
| 26 | F | C | 0.0000 | |
| 27 | P | C | 0.0000 | |
| 28 | V | C | 0.0000 | |
| 29 | G | C | 0.0000 | |
| 30 | R | C | -0.2133 | |
| 31 | V | C | 0.0000 | |
| 32 | H | C | -0.1669 | |
| 33 | R | C | -0.2571 | |
| 34 | L | C | 0.2002 | |
| 35 | L | C | 0.0000 | |
| 36 | R | C | -1.9338 | |
| 37 | K | C | -2.0147 | |
| 38 | G | C | -0.4812 | |
| 39 | N | C | -0.4457 | |
| 40 | Y | C | 0.0925 | |
| 41 | S | C | -0.3315 | |
| 42 | E | C | -1.8709 | |
| 43 | R | C | -0.5864 | |
| 44 | V | C | 0.0000 | |
| 45 | G | C | 0.0000 | |
| 46 | A | C | 0.0021 | |
| 47 | G | C | -0.1513 | |
| 48 | A | C | 0.0000 | |
| 49 | P | C | 0.0000 | |
| 50 | V | C | 0.0000 | |
| 51 | Y | C | 0.0000 | |
| 52 | L | C | 0.0000 | |
| 53 | A | C | 0.0000 | |
| 54 | A | C | 0.0000 | |
| 55 | V | C | 0.0000 | |
| 56 | L | C | 0.0000 | |
| 57 | E | C | -0.2526 | |
| 58 | Y | C | 0.0000 | |
| 59 | L | C | 0.0000 | |
| 60 | T | C | 0.0000 | |
| 61 | A | C | -0.1018 | |
| 62 | E | C | -0.6073 | |
| 63 | I | C | 0.0000 | |
| 64 | L | C | 0.0000 | |
| 65 | E | C | -1.4833 | |
| 66 | L | C | 0.1854 | |
| 67 | A | C | 0.0000 | |
| 68 | G | C | 0.0000 | |
| 69 | N | C | -0.7812 | |
| 70 | A | C | -0.1005 | |
| 71 | A | C | 0.0000 | |
| 72 | R | C | -2.2411 | |
| 73 | D | C | -2.2572 | |
| 74 | N | C | -1.3200 | |
| 75 | K | C | -1.8953 | |
| 76 | K | C | -0.7086 | |
| 77 | T | C | -0.1715 | |
| 78 | R | C | -0.3348 | |
| 79 | I | C | 0.0000 | |
| 80 | I | C | 0.3237 | |
| 81 | P | C | -0.0316 | |
| 82 | R | C | -0.3711 | |
| 83 | H | C | 0.0000 | |
| 84 | L | C | 0.0000 | |
| 85 | Q | C | -0.1202 | |
| 86 | L | C | 0.1919 | |
| 87 | A | C | 0.0000 | |
| 88 | I | C | 0.0000 | |
| 89 | R | C | -1.3539 | |
| 90 | N | C | -1.5576 | |
| 91 | D | C | -0.9941 | |
| 92 | E | C | -2.0030 | |
| 93 | E | C | -1.0812 | |
| 94 | L | C | 0.0000 | |
| 95 | N | C | -0.5889 | |
| 96 | K | C | -1.7688 | |
| 97 | L | C | -0.0937 | |
| 98 | L | C | 0.0000 | |
| 99 | G | C | -0.8097 | |
| 100 | R | C | -1.8939 | |
| 101 | V | C | -0.1419 | |
| 102 | T | C | 0.0257 | |
| 103 | I | C | 0.0000 | |
| 104 | A | C | 0.0000 | |
| 105 | Q | C | -0.2701 | |
| 106 | G | C | 0.0000 | |
| 107 | G | C | -0.0382 | |
| 108 | V | C | 0.3489 | |
| 109 | L | C | 0.3152 | |
| 110 | P | C | -0.3343 | |
| 111 | N | C | -0.7063 | |
| 112 | I | C | 0.2059 | |
| 113 | Q | C | -0.1752 | |
| 114 | A | C | 0.3361 | |
| 115 | V | C | 1.7835 | |
| 116 | L | C | 0.0000 | |
| 117 | L | C | 1.5009 | |
| 118 | P | C | 0.0289 | |
| 32 | R | D | -1.8835 | |
| 33 | S | D | -0.7296 | |
| 34 | R | D | -1.3007 | |
| 35 | K | D | -1.9733 | |
| 36 | E | D | -0.8526 | |
| 37 | S | D | -0.1484 | |
| 38 | Y | D | 0.0000 | |
| 39 | S | D | 0.1243 | |
| 40 | I | D | 1.0261 | |
| 41 | Y | D | 0.0000 | |
| 42 | V | D | 0.0000 | |
| 43 | Y | D | 0.2400 | |
| 44 | K | D | -0.7640 | |
| 45 | V | D | 0.0000 | |
| 46 | L | D | 0.0000 | |
| 47 | K | D | -1.9509 | |
| 48 | Q | D | -1.4510 | |
| 49 | V | D | 0.0843 | |
| 50 | H | D | -0.1519 | |
| 51 | P | D | -0.8056 | |
| 52 | D | D | -1.8359 | |
| 53 | T | D | 0.0000 | |
| 54 | G | D | -0.0957 | |
| 55 | I | D | 0.0000 | |
| 56 | S | D | -0.0753 | |
| 57 | S | D | -0.4014 | |
| 58 | K | D | -1.0280 | |
| 59 | A | D | 0.0000 | |
| 60 | M | D | 0.0982 | |
| 61 | G | D | -0.1043 | |
| 62 | I | D | 0.0000 | |
| 63 | M | D | 0.0000 | |
| 64 | N | D | -0.1612 | |
| 65 | S | D | -0.0491 | |
| 66 | F | D | 0.0000 | |
| 67 | V | D | 0.0000 | |
| 68 | N | D | -0.9140 | |
| 69 | D | D | -0.4515 | |
| 70 | I | D | 0.0000 | |
| 71 | F | D | 0.0000 | |
| 72 | E | D | -1.1245 | |
| 73 | R | D | -0.9686 | |
| 74 | I | D | 0.0000 | |
| 75 | A | D | 0.0000 | |
| 76 | G | D | -0.1986 | |
| 77 | E | D | -0.1909 | |
| 78 | A | D | 0.0000 | |
| 79 | S | D | -0.2335 | |
| 80 | R | D | -1.1718 | |
| 81 | L | D | 0.0000 | |
| 82 | A | D | -0.1220 | |
| 83 | H | D | -0.7684 | |
| 84 | Y | D | 0.0463 | |
| 85 | N | D | -0.4877 | |
| 86 | K | D | -2.0793 | |
| 87 | R | D | -2.1678 | |
| 88 | S | D | -0.3991 | |
| 89 | T | D | 0.0000 | |
| 90 | I | D | 0.0000 | |
| 91 | T | D | -0.0360 | |
| 92 | S | D | -0.1922 | |
| 93 | R | D | -0.6434 | |
| 94 | E | D | -0.3231 | |
| 95 | I | D | 0.0000 | |
| 96 | Q | D | -0.4361 | |
| 97 | T | D | 0.0000 | |
| 98 | A | D | 0.0000 | |
| 99 | V | D | 0.0000 | |
| 100 | R | D | -0.7257 | |
| 101 | L | D | 0.0000 | |
| 102 | L | D | 0.2115 | |
| 103 | L | D | 0.0000 | |
| 104 | P | D | -0.0992 | |
| 105 | G | D | -0.6609 | |
| 106 | E | D | -1.8499 | |
| 107 | L | D | -0.1789 | |
| 108 | A | D | 0.0000 | |
| 109 | K | D | -1.8369 | |
| 110 | H | D | -1.0647 | |
| 111 | A | D | 0.0000 | |
| 112 | V | D | 0.2151 | |
| 113 | S | D | -0.2877 | |
| 114 | E | D | -0.7142 | |
| 115 | G | D | 0.0000 | |
| 116 | T | D | -0.3479 | |
| 117 | K | D | -1.7039 | |
| 118 | A | D | 0.0000 | |
| 119 | V | D | 0.3269 | |
| 120 | T | D | -0.1834 | |
| 121 | K | D | -1.0581 | |
| 122 | Y | D | 0.0530 | |
| 123 | T | D | -0.0709 | |
| 124 | S | D | -0.3408 | |
| 125 | A | D | 0.0193 | |
| 45 | Q | E | -1.2568 | |
| 46 | G | E | -0.7069 | |
| 47 | W | E | 0.0272 | |
| 48 | L | E | 0.0624 | |
| 49 | K | E | -1.8505 | |
| 50 | E | E | -1.2707 | |
| 51 | I | E | 0.0000 | |
| 52 | R | E | -2.1584 | |
| 53 | K | E | -2.0410 | |
| 54 | L | E | 0.0000 | |
| 55 | Q | E | 0.0000 | |
| 56 | K | E | -1.7145 | |
| 57 | S | E | -0.3955 | |
| 58 | T | E | -0.2210 | |
| 59 | H | E | -0.9359 | |
| 60 | L | E | 0.1203 | |
| 61 | L | E | 0.0000 | |
| 62 | I | E | 0.0000 | |
| 63 | R | E | -0.6204 | |
| 64 | K | E | -0.7321 | |
| 65 | L | E | 0.6052 | |
| 66 | P | E | 0.0000 | |
| 67 | F | E | 0.0000 | |
| 68 | S | E | -0.2078 | |
| 69 | R | E | -1.0117 | |
| 70 | L | E | 0.0000 | |
| 71 | A | E | 0.0000 | |
| 72 | R | E | -0.6348 | |
| 73 | E | E | -0.9872 | |
| 74 | I | E | 0.0000 | |
| 75 | C | E | 0.0000 | |
| 76 | V | E | 0.8436 | |
| 77 | K | E | -1.4222 | |
| 78 | F | E | 0.0108 | |
| 79 | T | E | -0.2867 | |
| 80 | R | E | -1.8889 | |
| 81 | G | E | -0.0806 | |
| 82 | V | E | 1.4043 | |
| 83 | D | E | -1.4679 | |
| 84 | F | E | 0.0000 | |
| 85 | N | E | -0.2099 | |
| 86 | W | E | 0.0000 | |
| 87 | Q | E | -0.3098 | |
| 88 | A | E | -0.1388 | |
| 89 | Q | E | -0.7273 | |
| 90 | A | E | 0.0000 | |
| 91 | L | E | 0.0000 | |
| 92 | L | E | 0.3110 | |
| 93 | A | E | 0.0000 | |
| 94 | L | E | 0.0000 | |
| 95 | Q | E | 0.0000 | |
| 96 | E | E | 0.0000 | |
| 97 | A | E | 0.0000 | |
| 98 | A | E | 0.0000 | |
| 99 | E | E | 0.0000 | |
| 100 | A | E | 0.0502 | |
| 101 | F | E | 0.2098 | |
| 102 | L | E | 0.0000 | |
| 103 | V | E | 0.0000 | |
| 104 | H | E | -0.6067 | |
| 105 | L | E | 0.0000 | |
| 106 | F | E | 0.0000 | |
| 107 | E | E | -0.6380 | |
| 108 | D | E | -0.3320 | |
| 109 | A | E | 0.0000 | |
| 110 | Y | E | 0.0000 | |
| 111 | L | E | 0.1605 | |
| 112 | L | E | 0.0000 | |
| 113 | T | E | 0.0000 | |
| 114 | L | E | 0.2891 | |
| 115 | H | E | 0.0000 | |
| 116 | A | E | 0.0000 | |
| 117 | G | E | -0.5703 | |
| 118 | R | E | -0.5926 | |
| 119 | V | E | 0.1933 | |
| 120 | T | E | 0.0000 | |
| 121 | L | E | 0.0000 | |
| 122 | F | E | 0.3195 | |
| 123 | P | E | -0.3034 | |
| 124 | K | E | -1.7090 | |
| 125 | D | E | 0.0000 | |
| 126 | V | E | 0.0000 | |
| 127 | Q | E | -1.1821 | |
| 128 | L | E | 0.0000 | |
| 129 | A | E | 0.0000 | |
| 130 | R | E | -1.0629 | |
| 131 | R | E | -1.9563 | |
| 132 | I | E | 0.0000 | |
| 133 | R | E | -0.7400 | |
| 134 | G | E | -0.3017 | |
| 135 | L | E | 1.4617 | |
| 24 | R | F | -2.1633 | |
| 25 | D | F | -2.1241 | |
| 26 | N | F | -0.5596 | |
| 27 | I | F | -0.0301 | |
| 28 | Q | F | -1.1718 | |
| 29 | G | F | -0.3490 | |
| 30 | I | F | 0.0000 | |
| 31 | T | F | -0.2609 | |
| 32 | K | F | -1.3623 | |
| 33 | P | F | -0.3642 | |
| 34 | A | F | 0.0000 | |
| 35 | I | F | 0.0000 | |
| 36 | R | F | -0.6657 | |
| 37 | R | F | -0.4273 | |
| 38 | L | F | 0.0000 | |
| 39 | A | F | 0.0000 | |
| 40 | R | F | 0.0000 | |
| 41 | R | F | 0.0000 | |
| 42 | G | F | -0.0517 | |
| 43 | G | F | 0.0000 | |
| 44 | V | F | 0.0000 | |
| 45 | K | F | -0.3177 | |
| 46 | R | F | -0.2456 | |
| 47 | I | F | 0.0000 | |
| 48 | S | F | -0.0666 | |
| 49 | G | F | 0.0601 | |
| 50 | L | F | 1.5060 | |
| 51 | I | F | 0.0000 | |
| 52 | Y | F | 0.0000 | |
| 53 | E | F | -1.8651 | |
| 54 | E | F | -0.6046 | |
| 55 | T | F | 0.0000 | |
| 56 | R | F | -0.3066 | |
| 57 | G | F | -0.2967 | |
| 58 | V | F | 0.0000 | |
| 59 | L | F | 0.0000 | |
| 60 | K | F | -0.5541 | |
| 61 | V | F | 1.4010 | |
| 62 | F | F | 0.0000 | |
| 63 | L | F | 0.0000 | |
| 64 | E | F | -1.4712 | |
| 65 | N | F | -1.3912 | |
| 66 | V | F | 0.0000 | |
| 67 | I | F | 0.0000 | |
| 68 | R | F | -0.4310 | |
| 69 | D | F | 0.0000 | |
| 70 | A | F | 0.0000 | |
| 71 | V | F | 0.0000 | |
| 72 | T | F | 0.0000 | |
| 73 | Y | F | 0.0000 | |
| 74 | T | F | 0.0000 | |
| 75 | E | F | -0.3861 | |
| 76 | H | F | -0.1749 | |
| 77 | A | F | -0.3240 | |
| 78 | K | F | -1.7524 | |
| 79 | R | F | -0.7660 | |
| 80 | K | F | -0.8795 | |
| 81 | T | F | 0.0000 | |
| 82 | V | F | 0.0000 | |
| 83 | T | F | -0.0078 | |
| 84 | A | F | 0.0468 | |
| 85 | M | F | 0.2289 | |
| 86 | D | F | 0.0000 | |
| 87 | V | F | 0.0000 | |
| 88 | V | F | 0.0000 | |
| 89 | Y | F | 0.1109 | |
| 90 | A | F | 0.0000 | |
| 91 | L | F | 0.0000 | |
| 92 | K | F | -0.6664 | |
| 93 | R | F | -0.8981 | |
| 94 | Q | F | -0.5349 | |
| 95 | G | F | -0.2279 | |
| 96 | R | F | -0.3210 | |
| 97 | T | F | -0.0417 | |
| 98 | L | F | 0.0000 | |
| 99 | Y | F | 0.0000 | |
| 100 | G | F | -0.0131 | |
| 101 | F | F | 0.2923 | |
| 102 | G | F | -0.1183 | |
| 103 | G | F | -0.4831 | |
| 12 | R | G | -1.8332 | |
| 13 | A | G | -0.5995 | |
| 14 | K | G | -1.6848 | |
| 15 | A | G | -0.4811 | |
| 16 | K | G | -1.0299 | |
| 17 | T | G | -0.3186 | |
| 18 | R | G | -0.6707 | |
| 19 | S | G | 0.0000 | |
| 20 | S | G | -0.3737 | |
| 21 | R | G | -1.2204 | |
| 22 | A | G | 0.0000 | |
| 23 | G | G | -0.4445 | |
| 24 | L | G | 0.0385 | |
| 25 | Q | G | -0.2911 | |
| 26 | F | G | 0.0000 | |
| 27 | P | G | 0.0000 | |
| 28 | V | G | 0.0000 | |
| 29 | G | G | -0.0820 | |
| 30 | R | G | -0.1951 | |
| 31 | V | G | 0.0000 | |
| 32 | H | G | -0.6006 | |
| 33 | R | G | -1.7062 | |
| 34 | L | G | 0.2376 | |
| 35 | L | G | 0.0000 | |
| 36 | R | G | -1.7274 | |
| 37 | K | G | -1.8522 | |
| 38 | G | G | -0.4358 | |
| 39 | N | G | -0.3878 | |
| 40 | Y | G | 0.0000 | |
| 41 | S | G | -0.3641 | |
| 42 | E | G | -1.8718 | |
| 43 | R | G | -0.5929 | |
| 44 | V | G | 0.0000 | |
| 45 | G | G | 0.0000 | |
| 46 | A | G | 0.0169 | |
| 47 | G | G | -0.0926 | |
| 48 | A | G | 0.0000 | |
| 49 | P | G | 0.0000 | |
| 50 | V | G | 0.0000 | |
| 51 | Y | G | 0.0000 | |
| 52 | L | G | 0.0000 | |
| 53 | A | G | 0.0000 | |
| 54 | A | G | 0.0000 | |
| 55 | V | G | 0.0000 | |
| 56 | L | G | 0.0000 | |
| 57 | E | G | -0.2395 | |
| 58 | Y | G | 0.0943 | |
| 59 | L | G | 0.0000 | |
| 60 | T | G | 0.0000 | |
| 61 | A | G | -0.0746 | |
| 62 | E | G | -0.4443 | |
| 63 | I | G | 0.0000 | |
| 64 | L | G | 0.0000 | |
| 65 | E | G | -1.1158 | |
| 66 | L | G | 0.2890 | |
| 67 | A | G | 0.0000 | |
| 68 | G | G | 0.0000 | |
| 69 | N | G | -1.4521 | |
| 70 | A | G | -0.2297 | |
| 71 | A | G | 0.0000 | |
| 72 | R | G | -2.0702 | |
| 73 | D | G | -2.2579 | |
| 74 | N | G | -1.5748 | |
| 75 | K | G | -1.9373 | |
| 76 | K | G | -0.6824 | |
| 77 | T | G | -0.1503 | |
| 78 | R | G | -0.3214 | |
| 79 | I | G | 0.0000 | |
| 80 | I | G | 0.4512 | |
| 81 | P | G | 0.0000 | |
| 82 | R | G | -0.1942 | |
| 83 | H | G | 0.0000 | |
| 84 | L | G | 0.0000 | |
| 85 | Q | G | 0.0000 | |
| 86 | L | G | 0.2194 | |
| 87 | A | G | 0.0000 | |
| 88 | I | G | 0.0000 | |
| 89 | R | G | -0.5182 | |
| 90 | N | G | -1.4115 | |
| 91 | D | G | -1.0399 | |
| 92 | E | G | -1.9620 | |
| 93 | E | G | -0.8147 | |
| 94 | L | G | 0.0000 | |
| 95 | N | G | -0.8799 | |
| 96 | K | G | -1.8029 | |
| 97 | L | G | -0.1362 | |
| 98 | L | G | 0.0000 | |
| 99 | G | G | -0.8098 | |
| 100 | R | G | -1.9309 | |
| 101 | V | G | 0.0000 | |
| 102 | T | G | -0.0091 | |
| 103 | I | G | 0.0000 | |
| 104 | A | G | 0.0000 | |
| 105 | Q | G | -0.2383 | |
| 106 | G | G | 0.0000 | |
| 107 | G | G | -0.0534 | |
| 108 | V | G | 0.3135 | |
| 109 | L | G | 0.3361 | |
| 110 | P | G | -0.3899 | |
| 111 | N | G | -1.0186 | |
| 112 | I | G | 0.1954 | |
| 113 | Q | G | -0.3323 | |
| 114 | A | G | 0.3039 | |
| 115 | V | G | 1.7835 | |
| 116 | L | G | 0.0000 | |
| 117 | L | G | 1.5010 | |
| 118 | P | G | 0.0287 | |
| 32 | R | H | -1.8830 | |
| 33 | S | H | -0.6684 | |
| 34 | R | H | -0.9957 | |
| 35 | K | H | -2.1569 | |
| 36 | E | H | -2.1459 | |
| 37 | S | H | -0.3947 | |
| 38 | Y | H | 0.0000 | |
| 39 | S | H | -0.0225 | |
| 40 | I | H | 0.6992 | |
| 41 | Y | H | 0.0000 | |
| 42 | V | H | 0.0000 | |
| 43 | Y | H | 0.0796 | |
| 44 | K | H | -0.8151 | |
| 45 | V | H | 0.0000 | |
| 46 | L | H | 0.0000 | |
| 47 | K | H | -1.1450 | |
| 48 | Q | H | -1.2371 | |
| 49 | V | H | 0.4959 | |
| 50 | H | H | 0.0000 | |
| 51 | P | H | -0.5870 | |
| 52 | D | H | -1.8367 | |
| 53 | T | H | 0.0000 | |
| 54 | G | H | -0.1077 | |
| 55 | I | H | 0.0000 | |
| 56 | S | H | -0.0623 | |
| 57 | S | H | -0.4166 | |
| 58 | K | H | -1.1143 | |
| 59 | A | H | 0.0000 | |
| 60 | M | H | 0.1214 | |
| 61 | G | H | -0.0541 | |
| 62 | I | H | 0.0000 | |
| 63 | M | H | 0.0000 | |
| 64 | N | H | -0.1641 | |
| 65 | S | H | -0.0515 | |
| 66 | F | H | 0.0000 | |
| 67 | V | H | 0.0000 | |
| 68 | N | H | -1.2020 | |
| 69 | D | H | -0.4469 | |
| 70 | I | H | 0.0000 | |
| 71 | F | H | 0.0000 | |
| 72 | E | H | -1.1840 | |
| 73 | R | H | -0.6367 | |
| 74 | I | H | 0.0000 | |
| 75 | A | H | 0.0000 | |
| 76 | G | H | -0.0718 | |
| 77 | E | H | 0.0000 | |
| 78 | A | H | 0.0000 | |
| 79 | S | H | -0.2277 | |
| 80 | R | H | -1.0999 | |
| 81 | L | H | 0.0000 | |
| 82 | A | H | 0.0000 | |
| 83 | H | H | -0.7333 | |
| 84 | Y | H | 0.0613 | |
| 85 | N | H | -0.5051 | |
| 86 | K | H | -1.9538 | |
| 87 | R | H | -1.1897 | |
| 88 | S | H | -0.2345 | |
| 89 | T | H | 0.0000 | |
| 90 | I | H | 0.0000 | |
| 91 | T | H | -0.0186 | |
| 92 | S | H | -0.1990 | |
| 93 | R | H | -0.7672 | |
| 94 | E | H | 0.0000 | |
| 95 | I | H | 0.0000 | |
| 96 | Q | H | -0.5763 | |
| 97 | T | H | -0.2127 | |
| 98 | A | H | 0.0000 | |
| 99 | V | H | 0.0000 | |
| 100 | R | H | -0.8276 | |
| 101 | L | H | 0.0000 | |
| 102 | L | H | 0.0000 | |
| 103 | L | H | 0.0000 | |
| 104 | P | H | -0.0644 | |
| 105 | G | H | -0.5442 | |
| 106 | E | H | -1.8574 | |
| 107 | L | H | 0.0000 | |
| 108 | A | H | 0.0000 | |
| 109 | K | H | -1.8851 | |
| 110 | H | H | -1.3079 | |
| 111 | A | H | 0.0000 | |
| 112 | V | H | 0.3862 | |
| 113 | S | H | -0.1332 | |
| 114 | E | H | -0.7258 | |
| 115 | G | H | 0.0000 | |
| 116 | T | H | -0.3506 | |
| 117 | K | H | -1.7052 | |
| 118 | A | H | 0.0000 | |
| 119 | V | H | 0.2205 | |
| 120 | T | H | -0.2686 | |
| 121 | K | H | -1.2665 | |
| 122 | Y | H | -0.0176 | |
| 123 | T | H | -0.0667 | |
| 124 | S | H | -0.2151 | |
| 125 | A | H | 0.0192 | |
| 1 | M | N | 0.7175 | |
| 2 | D | N | -0.9909 | |
| 3 | E | N | -1.7317 | |
| 4 | T | N | -0.1905 | |
| 5 | V | N | 0.0000 | |
| 6 | A | N | -0.1723 | |
| 7 | E | N | 0.0000 | |
| 8 | F | N | 0.0000 | |
| 9 | I | N | 0.0000 | |
| 10 | K | N | -0.8327 | |
| 11 | R | N | -0.6457 | |
| 12 | T | N | 0.0000 | |
| 13 | I | N | 0.0000 | |
| 14 | L | N | 0.3985 | |
| 15 | K | N | -1.5686 | |
| 16 | I | N | 0.0000 | |
| 17 | P | N | 0.0173 | |
| 18 | M | N | 0.0789 | |
| 19 | N | N | -1.3848 | |
| 20 | E | N | -1.1157 | |
| 21 | L | N | 0.0113 | |
| 22 | T | N | -0.0547 | |
| 23 | T | N | -0.0779 | |
| 24 | I | N | 0.0000 | |
| 25 | L | N | 0.0000 | |
| 26 | K | N | -1.4465 | |
| 27 | A | N | -0.1985 | |
| 28 | W | N | -0.1615 | |
| 29 | D | N | -1.7156 | |
| 30 | F | N | -0.0827 | |
| 31 | L | N | 0.0000 | |
| 32 | S | N | -0.3841 | |
| 33 | E | N | -2.0641 | |
| 34 | N | N | -1.6564 | |
| 35 | Q | N | -0.3817 | |
| 36 | L | N | 0.2979 | |
| 37 | Q | N | -1.0936 | |
| 42 | R | N | -2.0642 | |
| 43 | Q | N | -1.8088 | |
| 44 | R | N | -1.7582 | |
| 45 | K | N | -0.7430 | |
| 46 | E | N | -1.3006 | |
| 47 | S | N | -0.3292 | |
| 48 | V | N | 0.2769 | |
| 49 | V | N | 0.0000 | |
| 50 | Q | N | -1.2101 | |
| 51 | H | N | -1.1777 | |
| 52 | L | N | 0.0000 | |
| 53 | I | N | 0.1525 | |
| 54 | H | N | -0.8665 | |
| 55 | L | N | 0.1739 | |
| 56 | C | N | -0.1601 | |
| 57 | E | N | -2.3312 | |
| 58 | E | N | -2.4682 | |
| 59 | K | N | -2.3678 | |
| 60 | R | N | -2.3375 | |
| 64 | S | N | -0.5449 | |
| 65 | D | N | -1.8289 | |
| 66 | A | N | 0.0000 | |
| 67 | A | N | 0.0000 | |
| 68 | L | N | 0.4526 | |
| 69 | L | N | 0.0000 | |
| 70 | D | N | -0.2786 | |
| 71 | I | N | 0.0000 | |
| 72 | I | N | 0.0000 | |
| 73 | Y | N | 0.0000 | |
| 74 | M | N | 0.0916 | |
| 75 | Q | N | 0.0023 | |
| 76 | F | N | 1.2472 | |
| 77 | H | N | -0.2934 | |
| 78 | Q | N | -1.4431 | |
| 79 | H | N | -1.4277 | |
| 80 | Q | N | -1.6886 | |
| 81 | K | N | -1.9190 | |
| 101 | M | N | 0.8986 | |
| 102 | K | N | -0.8795 | |
| 103 | Q | N | -1.3206 | |
| 104 | F | N | -0.0285 | |
| 105 | K | N | 0.0000 | |
| 106 | N | N | -0.7682 | |
| 107 | S | N | -0.2996 | |
| 108 | F | N | -0.0935 | |
| 109 | K | N | -1.9629 | |
| 110 | K | N | -2.0110 | |
| 119 | V | N | 0.2558 | |
| 120 | T | N | 0.0617 | |
| 121 | V | N | 0.2067 | |
| 122 | S | N | 0.0981 | |
| 123 | F | N | 0.3140 | |
| 124 | R | N | -0.9884 | |
| 125 | E | N | -1.9650 | |
| 126 | T | N | -0.3840 | |
| 130 | A | N | 0.3862 | |
| 131 | V | N | 1.8270 | |
| 132 | W | N | 0.5816 | |
| 133 | I | N | 0.1934 | |
| 134 | R | N | -0.2055 | |
| 135 | I | N | 0.0000 | |
| 136 | A | N | 0.0000 | |
| 137 | W | N | 0.0000 | |
| 138 | G | N | 0.0000 | |
| 139 | T | N | -0.0259 | |
| 143 | K | N | -1.7468 | |
| 144 | P | N | -0.6757 | |
| 145 | N | N | -0.6691 | |
| 146 | Q | N | -0.1988 | |
| 147 | Y | N | 0.0064 | |
| 148 | K | N | -0.6482 | |
| 149 | P | N | -0.3739 | |
| 150 | T | N | 0.0725 | |
| 151 | Y | N | 0.7393 | |
| 152 | V | N | 0.3912 | |
| 153 | V | N | 0.5964 | |
| 154 | Y | N | 1.4883 | |
| 155 | Y | N | 0.8417 | |
| 156 | S | N | -0.2085 | |
| 157 | Q | N | -1.2225 | |
| 169 | R | N | -1.3787 | |
| 170 | R | N | -2.0943 | |
| 171 | N | N | -0.6730 | |
| 172 | T | N | -0.1763 | |
| 173 | P | N | -0.1322 | |
| 174 | L | N | 0.5737 | |
| 175 | L | N | 0.0000 | |
| 176 | G | N | -0.6885 | |
| 177 | Q | N | -1.2074 | |
| 178 | A | N | -0.2104 | |
| 179 | L | N | 0.0000 | |
| 180 | T | N | 0.2982 | |
| 181 | I | N | 1.9891 | |
| 182 | A | N | 0.3908 | |
| 183 | S | N | -0.4458 | |
| 184 | K | N | -1.9035 | |
| 185 | H | N | -1.2942 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine