Project name: 11c602a8d6c1e6a

Chain sequence(s)	A: MSKGEELFTGVVPILVELDGDVNGHKFSVSGEGEGDATYGKLTLKFICTTGKLPVPWPTLVTTFVQCFSRYPDHMKRHDFFKSAMPEGYVQERTIFFKDDGNYKTRAEVKFEGDTLVNRIELKGIDFKEDGNILGHKLEYNFNSHNVYIMADKQKNGIKVNFKIRHNIEDGSVQLADHYQQNTPIGDGPVLLPDNHYLSTQSALSKDPNEKRDHMVLLEFVTAAGI
Distance of aggregation	10 Å
Dynamic mode	No

• Minimal score value: -4.1937
• Maximal score value: 1.2568
• Average score: -1.0281
• Total score value: -232.3498

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	-0.0157
2	S	A	-1.5597
3	K	A	-2.3167
4	G	A	0.0000
5	E	A	-2.6383
6	E	A	-2.6434
7	L	A	-1.4949
8	F	A	0.0000
9	T	A	-0.6644
10	G	A	0.2178
11	V	A	1.0103
12	V	A	0.0000
13	P	A	-1.0436
14	I	A	0.0000
15	L	A	-1.1551
16	V	A	0.0000
17	E	A	-2.1049
18	L	A	0.0000
19	D	A	-3.5583
20	G	A	0.0000
21	D	A	-2.6467
22	V	A	0.0000
23	N	A	-1.9747
24	G	A	-1.5789
25	H	A	-1.9215
26	K	A	-2.8557
27	F	A	0.0000
28	S	A	-1.7361
29	V	A	0.0000
30	S	A	-1.0627
31	G	A	0.0000
32	E	A	-2.2536
33	G	A	-1.5654
34	E	A	-1.7369
35	G	A	0.0000
36	D	A	-0.0461
37	A	A	0.0000
38	T	A	0.1876
39	Y	A	0.7297
40	G	A	0.0000
41	K	A	-0.5011
42	L	A	0.0000
43	T	A	-0.9146
44	L	A	0.0000
45	K	A	-1.2732
46	F	A	0.0000
47	I	A	-0.8944
48	C	A	0.0000
49	T	A	-0.7192
50	T	A	-1.1209
51	G	A	-1.5645
52	K	A	-2.2073
53	L	A	0.0000
54	P	A	-1.1433
55	V	A	0.0000
56	P	A	0.0000
57	W	A	0.0000
58	P	A	0.0000
59	T	A	0.0000
60	L	A	0.0000
61	V	A	0.0000
62	T	A	-0.0043
63	T	A	0.0000
64	F	A	0.0000
68	V	A	-0.0292
69	Q	A	-0.2379
70	C	A	0.0000
71	F	A	0.0000
72	S	A	0.0000
73	R	A	-1.3482
74	Y	A	0.0000
75	P	A	-1.8347
76	D	A	-3.0734
77	H	A	-2.2163
78	M	A	0.0000
79	K	A	-3.2260
80	R	A	-2.8764
81	H	A	-1.7254
82	D	A	0.0000
83	F	A	0.0000
84	F	A	0.0000
85	K	A	-1.1513
86	S	A	0.0000
87	A	A	0.0000
88	M	A	0.0000
89	P	A	-1.8756
90	E	A	-1.9665
91	G	A	0.0000
92	Y	A	0.0000
93	V	A	-0.8991
94	Q	A	0.0000
95	E	A	-2.2299
96	R	A	0.0000
97	T	A	-0.5136
98	I	A	0.0000
99	F	A	0.2156
100	F	A	0.0000
101	K	A	-2.0998
102	D	A	-2.9538
103	D	A	-2.6584
104	G	A	0.0000
105	N	A	-0.8444
106	Y	A	0.0000
107	K	A	-2.0232
108	T	A	0.0000
109	R	A	-3.3268
110	A	A	0.0000
111	E	A	-1.9177
112	V	A	0.0000
113	K	A	-1.8268
114	F	A	0.0000
115	E	A	-2.8153
116	G	A	-2.3531
117	D	A	-2.6207
118	T	A	-1.8544
119	L	A	0.0000
120	V	A	0.0000
121	N	A	0.0000
122	R	A	-3.1695
123	I	A	0.0000
124	E	A	-4.1937
125	L	A	0.0000
126	K	A	-2.9701
127	G	A	0.0000
128	I	A	-1.0480
129	D	A	-2.3967
130	F	A	0.0000
131	K	A	-3.9767
132	E	A	-3.9699
133	D	A	-3.6000
134	G	A	-2.8192
135	N	A	-2.3460
136	I	A	0.0000
137	L	A	-1.9749
138	G	A	-2.1877
139	H	A	-1.9727
140	K	A	-2.5836
141	L	A	-2.2433
142	E	A	-2.7564
143	Y	A	-1.4550
144	N	A	-1.7603
145	F	A	-1.7168
146	N	A	-2.0039
147	S	A	-1.5158
148	H	A	-1.5757
149	N	A	-1.2084
150	V	A	0.0000
151	Y	A	0.1852
152	I	A	0.0000
153	M	A	-0.9790
154	A	A	-1.8040
155	D	A	-2.1535
156	K	A	-3.0761
157	Q	A	-2.9880
158	K	A	-3.2896
159	N	A	-2.6926
160	G	A	0.0000
161	I	A	0.0000
162	K	A	-1.1041
163	V	A	0.0000
164	N	A	-0.4739
165	F	A	0.0000
166	K	A	-1.9042
167	I	A	0.0000
168	R	A	-2.4651
169	H	A	0.0000
170	N	A	-2.7950
171	I	A	0.0000
172	E	A	-3.6394
173	D	A	-3.2532
174	G	A	-2.2201
175	S	A	-1.4782
176	V	A	-1.2624
177	Q	A	0.0000
178	L	A	-1.4218
179	A	A	0.0000
180	D	A	0.0000
181	H	A	0.0000
182	Y	A	0.1922
183	Q	A	0.0000
184	Q	A	-1.6107
185	N	A	0.0000
186	T	A	-0.7773
187	P	A	-0.8311
188	I	A	-0.4068
189	G	A	-1.3773
190	D	A	-2.3955
191	G	A	-1.7595
192	P	A	-1.2844
193	V	A	-0.9425
194	L	A	-0.9668
195	L	A	-1.2765
196	P	A	0.0000
197	D	A	-2.1059
198	N	A	-1.2645
199	H	A	0.0000
200	Y	A	0.1738
201	L	A	0.0000
202	S	A	-0.7002
203	T	A	0.0000
204	Q	A	-1.4929
205	S	A	-0.8082
206	A	A	-0.3906
207	L	A	0.0000
208	S	A	-0.9266
209	K	A	-1.7854
210	D	A	-2.0568
211	P	A	-1.8066
212	N	A	-2.4294
213	E	A	-2.6006
214	K	A	-2.9824
215	R	A	-2.9222
216	D	A	-2.0946
217	H	A	0.0000
218	M	A	0.0000
219	V	A	-0.3834
220	L	A	0.0000
221	L	A	0.1196
222	E	A	-0.2965
223	F	A	-0.0881
224	V	A	0.0000
225	T	A	-0.5106
226	A	A	0.0000
227	A	A	0.1417
228	G	A	0.3523
229	I	A	1.2568